Steven M Shapiro

Summary

Affiliation: Virginia Commonwealth University
Country: USA

Publications

  1. ncbi request reprint Somatosensory and brainstem auditory evoked potentials in the Gunn rat model of acute bilirubin neurotoxicity
    Steven M Shapiro
    Department of Neurology, Medical College of Virginia Campus, Virginia Commonwealth University Health System, Box 980599 MCV Station, Richmond, Virginia 23298 0599, USA
    Pediatr Res 52:844-9. 2002
  2. ncbi request reprint Minocycline blocks acute bilirubin-induced neurological dysfunction in jaundiced Gunn rats
    Angela S Geiger
    Department of Neurology and Physiology, Virginia Commonwealth University Medical Center, Virginia Commonwealth University, Richmond, VA, USA
    Neonatology 92:219-26. 2007
  3. ncbi request reprint NMDA channel antagonist MK-801 does not protect against bilirubin neurotoxicity
    Steven M Shapiro
    Department of Neurology, Virginia Commonwealth University, Richmond, VA 23298 0599, USA
    Neonatology 92:248-57. 2007
  4. doi request reprint A new animal model of hemolytic hyperbilirubinemia-induced bilirubin encephalopathy (kernicterus)
    Ann C Rice
    Department of Neurology, Virginia Commonwealth University, Richmond, Virginia 23298, USA
    Pediatr Res 64:265-9. 2008
  5. ncbi request reprint Immunohistochemical localization of calcium-binding proteins in the brainstem vestibular nuclei of the jaundiced Gunn rat
    Wayne T Shaia
    Department of Otolaryngology Head and Neck Surgery, School of Medicine, Medical College of Virginia Campus, Virginia Commonwealth University Health System, Richmond 23298 0599, USA
    Hear Res 173:82-90. 2002
  6. doi request reprint Quantification of gait in dystonic Gunn rats
    Kunal D Chaniary
    Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA 23298 0599, USA
    J Neurosci Methods 180:273-7. 2009
  7. pmc Profile of minocycline neuroprotection in bilirubin-induced auditory system dysfunction
    Ann C Rice
    Department of Neurology, Box 980599, Virginia Commonwealth University, Richmond, VA 23298 0599, USA
    Brain Res 1368:290-8. 2011
  8. ncbi request reprint Biliverdin-induced brainstem auditory evoked potential abnormalities in the jaundiced Gunn rat
    Ann C Rice
    Department of Neurology, Box 980599, Virginia Commonwealth University, Richmond, VA 23298 0599, USA
    Brain Res 1107:215-21. 2006
  9. pmc A novel stereotaxic apparatus for neuronal recordings in awake head-restrained rats
    Kunal D Chaniary
    Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA 23298 0599, USA
    J Neurosci Methods 198:29-35. 2011
  10. ncbi request reprint Bilirubin toxicity in the developing nervous system
    Steven M Shapiro
    Division of Pediatric Neurology, Department of Neurology, Medical College of Virginia Campus, Virginia Commonwealth University Health System, Virginia Commonwealth University, Richmond, Virginia 23298, USA
    Pediatr Neurol 29:410-21. 2003

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Somatosensory and brainstem auditory evoked potentials in the Gunn rat model of acute bilirubin neurotoxicity
    Steven M Shapiro
    Department of Neurology, Medical College of Virginia Campus, Virginia Commonwealth University Health System, Box 980599 MCV Station, Richmond, Virginia 23298 0599, USA
    Pediatr Res 52:844-9. 2002
    ..SEPs assess proprioception but not other somatosensory function or sensory integration. The results demonstrate the selectivity of acute bilirubin toxicity for the auditory nervous system...
  2. ncbi request reprint Minocycline blocks acute bilirubin-induced neurological dysfunction in jaundiced Gunn rats
    Angela S Geiger
    Department of Neurology and Physiology, Virginia Commonwealth University Medical Center, Virginia Commonwealth University, Richmond, VA, USA
    Neonatology 92:219-26. 2007
    ..Acute brainstem auditory evoked potential (BAEP) abnormalities occur after giving sulfadimethoxine to 16-day-old jaundiced Gunn rats to displace bilirubin into tissue including brain...
  3. ncbi request reprint NMDA channel antagonist MK-801 does not protect against bilirubin neurotoxicity
    Steven M Shapiro
    Department of Neurology, Virginia Commonwealth University, Richmond, VA 23298 0599, USA
    Neonatology 92:248-57. 2007
    ..The mechanism of bilirubin-induced neurotoxicity is not known. Many neurological insults are mediated through NMDA receptor activation...
  4. doi request reprint A new animal model of hemolytic hyperbilirubinemia-induced bilirubin encephalopathy (kernicterus)
    Ann C Rice
    Department of Neurology, Virginia Commonwealth University, Richmond, Virginia 23298, USA
    Pediatr Res 64:265-9. 2008
    ..This new model may be a more clinically relevant experimental model of kernicterus- and bilirubin-induced neurologic disorders...
  5. ncbi request reprint Immunohistochemical localization of calcium-binding proteins in the brainstem vestibular nuclei of the jaundiced Gunn rat
    Wayne T Shaia
    Department of Otolaryngology Head and Neck Surgery, School of Medicine, Medical College of Virginia Campus, Virginia Commonwealth University Health System, Richmond 23298 0599, USA
    Hear Res 173:82-90. 2002
    ....
  6. doi request reprint Quantification of gait in dystonic Gunn rats
    Kunal D Chaniary
    Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA 23298 0599, USA
    J Neurosci Methods 180:273-7. 2009
    ..This study demonstrates a valuable technique to objectively characterize dystonia in Gunn rats, which could have wide use for other experimental movement disorders as well...
  7. pmc Profile of minocycline neuroprotection in bilirubin-induced auditory system dysfunction
    Ann C Rice
    Department of Neurology, Box 980599, Virginia Commonwealth University, Richmond, VA 23298 0599, USA
    Brain Res 1368:290-8. 2011
    ..These studies indicate that minocycline has a graded neuroprotective effect when administered after acute bilirubin neurotoxicity...
  8. ncbi request reprint Biliverdin-induced brainstem auditory evoked potential abnormalities in the jaundiced Gunn rat
    Ann C Rice
    Department of Neurology, Box 980599, Virginia Commonwealth University, Richmond, VA 23298 0599, USA
    Brain Res 1107:215-21. 2006
    ....
  9. pmc A novel stereotaxic apparatus for neuronal recordings in awake head-restrained rats
    Kunal D Chaniary
    Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA 23298 0599, USA
    J Neurosci Methods 198:29-35. 2011
    ....
  10. ncbi request reprint Bilirubin toxicity in the developing nervous system
    Steven M Shapiro
    Division of Pediatric Neurology, Department of Neurology, Medical College of Virginia Campus, Virginia Commonwealth University Health System, Virginia Commonwealth University, Richmond, Virginia 23298, USA
    Pediatr Neurol 29:410-21. 2003
    ....
  11. pmc Multi-neuronal recordings in the Basal Ganglia in normal and dystonic rats
    Mark S Baron
    Department of Neurology, Virginia Commonwealth University Richmond, VA, USA
    Front Syst Neurosci 5:67. 2011
    ..Moreover, from our findings, we suggest that excessive movement related silencing of neuronal signaling in GP profoundly disinhibits EP and in turn contributes to sustained, unfocused dystonic muscle contractions...
  12. doi request reprint Auditory impairment in infants at risk for bilirubin-induced neurologic dysfunction
    Steven M Shapiro
    Division of Child Neurology, Department of Neurology, Medical College of Virginia Campus, Virginia Commonwealth University Medical Center, Richmond, VA 23298 0211, USA
    Semin Perinatol 35:162-70. 2011
    ..Intervention, including cochlear implants can be effective...
  13. ncbi request reprint Hyperbilirubinemia and kernicterus
    Steven M Shapiro
    Division of Child Neurology, Department of Neurology, Virginia Commonwealth University Medical Center, Virginia Commonwealth University, Richmond, 23298 0211, USA
    Clin Perinatol 33:387-410. 2006
    ....
  14. doi request reprint Chronic bilirubin encephalopathy: diagnosis and outcome
    Steven M Shapiro
    Divisions of Child Neurology and Clinical Neurophysiology, Department of Neurology, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 23298 0211, USA
    Semin Fetal Neonatal Med 15:157-63. 2010
    ..Proposed research definitions for kernicterus diagnosis in infants from 3 to 18 months are reviewed, as are treatments of auditory and motor deficits and other complications of bilirubin encephalopathy...
  15. ncbi request reprint Definition of the clinical spectrum of kernicterus and bilirubin-induced neurologic dysfunction (BIND)
    Steven M Shapiro
    Division of Child Neurology, Departments of Neurology and Pediatrics, Medical College of Virginia Campus, Virginia Commonwealth University Medical Center, Richmond, VA 33298, USA
    J Perinatol 25:54-9. 2005
    ....
  16. ncbi request reprint Changes in calcium-binding protein expression in the auditory brainstem nuclei of the jaundiced Gunn rat
    Robert F Spencer
    Department of Otolaryngology Head and Neck Surgery, School of Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, VA 23298, USA
    Hear Res 171:129-141. 2002
    ....
  17. ncbi request reprint The jaundiced gunn rat model of auditory neuropathy/dyssynchrony
    Wayne T Shaia
    Michigan Ear Institute, Providence Hospital, Farmington Hills, Michigan, USA
    Laryngoscope 115:2167-73. 2005
    ..We examined morphologic changes in the cochlea, spiral ganglion, and auditory nerve and relate these findings to current understanding of AN/AD...
  18. ncbi request reprint Toward understanding kernicterus: a challenge to improve the management of jaundiced newborns
    Richard P Wennberg
    Division of Neonatology, Department of Pediatrics, University of Washington, Box 356320, Seattle, WA 98195, USA
    Pediatrics 117:474-85. 2006
    ....
  19. ncbi request reprint Kernicterus in sick and preterm infants (1999-2002): a need for an effective preventive approach
    Vinod K Bhutani
    Department of Pediatrics, University of Pennsylvania School of Medicine, Center for Research on Reproduction and Women s Health, Philadelphia, PA 19140, USA
    Semin Perinatol 28:319-25. 2004
    ....