Research Topics
| C N SesslerSummaryAffiliation: Virginia Commonwealth University Country: USA Publications
| Collaborators
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Detail Information
Publications
Protocol-directed weaning: a process of continuous performance improvementVenkat Ramachandran
The Department of Medicine, Medical College of Virginia Campus of the Virginia Commonwealth University, Richmond, Virginia, USA
Crit Care 9:138-40. 2005..However, one must avoid selecting criteria that are too restrictive, potentially delaying the discontinuation of ventilation...
New concepts in sepsisCurtis N Sessler
Division of Pulmonary and Critical Care Medicine and Medical Respiratory Intensive Care Unit, Medical College of Virginia, Virginia Commonwealth University Health System, Richmond, VA 23289, USA
Curr Opin Crit Care 8:465-72. 2002....
The Richmond Agitation-Sedation Scale: validity and reliability in adult intensive care unit patientsCurtis N Sessler
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Virginia Commonwealth University Health System, Richmond, Virginia 23298, USA
Am J Respir Crit Care Med 166:1338-44. 2002..Our nurses described RASS as logical, easy to administer, and readily recalled. RASS has high reliability and validity in medical and surgical, ventilated and nonventilated, and sedated and nonsedated adult ICU patients...
Steroids for septic shock: back from the dead? (Con)Curtis N Sessler
Division of Pulmonary and Critical Care Medicine, Virginia Commonwealth University Health System, Medical College of Virginia Hospitals, Richmond 23298, USA
Chest 123:482S-9S. 2003....
Management of severe sepsis and septic shockCurtis N Sessler
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Virginia Commonwealth University Health System, Richmond, Virginia, USA
Curr Opin Crit Care 10:354-63. 2004..Recent publications (2003 and early 2004) have been systematically reviewed for important new original research and scholarly reviews, with an emphasis on clinical advances in adults...
Mechanical ventilation of patients with acute lung injuryC N Sessler
Department of Internal Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, USA
Crit Care Clin 14:707-29, vii. 1998..No single approach is best for all patients; adjustment of ventilatory parameters to individual characteristics, such as lung mechanics and gas exchange, is required...
Evaluating and monitoring analgesia and sedation in the intensive care unitCurtis N Sessler
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Virginia Commonwealth University Health System, Richmond, Virginia 23298, USA
Crit Care 12:S2. 2008..Further clarification of the roles of these tools, particularly within the context of patient safety, is needed, as is further technology development to eliminate artifacts and investigation to demonstrate added value...
Analgesia and sedation in the intensive care unit: an overview of the issuesCurtis N Sessler
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Virginia Commonwealth University Health System, Richmond, Virginia 23298, USA
Crit Care 12:S1. 2008....
Infection control and the prevention of nosocomial infections in the intensive care unitGonzalo M L Bearman
Division of Quality HealthCare, Virginia Commonwealth University Medical Center, Richmond, Virginia 23298 0019, USA
Semin Respir Crit Care Med 27:310-24. 2006..For greatest risk reduction, multifaceted programs ensuring maximal adherence with evidence-based infection control guidelines are needed...
Oral health status and development of ventilator-associated pneumonia: a descriptive studyCindy L Munro
Adult Health Department, School of Nursing, Virginia Commonwealth University, Richmond, VA 23298 0567, USA
Am J Crit Care 15:453-60. 2006..Ventilator-associated pneumonia is a significant cause of morbidity and mortality and may be influenced by oral health...
A controlled trial of universal gloving versus contact precautions for preventing the transmission of multidrug-resistant organismsGonzalo M L Bearman
Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, VA, USA
Am J Infect Control 35:650-5. 2007..Contact precautions are recommended to reduce the transmission of multidrug-resistant organisms. However, the optimal method for control of multidrug-resistant organisms remains unclear...
Patient-focused sedation and analgesia in the ICUCurtis N Sessler
Division of Pulmonary and Critical Care Medicine, Box 980050, Virginia Commonwealth University Health System, Richmond, VA 23298, USA
Chest 133:552-65. 2008..Finally, more work is needed to explore the relationship of critical illness and sedation management with long-term psychological outcomes...
Intensive care management of life-threatening avian influenza A (H5N1)Curtis N Sessler
Division of Pulmonary and Critical Care Medicine, Virginia Commonwealth University Health System, and Medical College of Virginia Hospitals, Richmond, Virginia, USA
Respirology 13:S27-32. 2008..Management of multiple organ failure may include vasopressor support for septic shock and renal replacement therapy for acute renal failure...
Protocolized and target-based sedation and analgesia in the ICUCurtis N Sessler
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Virginia Commonwealth University Health System, Box 980050, Richmond, VA 23298 0050, USA
Crit Care Clin 25:489-513, viii. 2009..Implementation of sedation algorithms in ICUs is a challenging process for which sufficient resources must be allocated...
Effect of timing of dialysis on mortality in critically ill, septic patients with acute renal failureDaniel E Carl
Department of Medicine, Division of Nephrology, Virginia Commonwealth University, Richmond, Virginia 23298 0160, USA
Hemodial Int 14:11-7. 2010..7, P=0.01), and 365 days (OR 3.5, 95% CI 1.2-10, P=0.02). Septic patients who started dialysis with a BUN <100 mg/dL had improved mortality rates up to 1 year after initiation of dialysis in this single-center, retrospective analysis...
Collaborative practice: development, implementation, and evaluation of a weaning protocol for patients receiving mechanical ventilationMary Jo Grap
Virginia Commonwealth University, Richmond, VA, USA
Am J Crit Care 12:454-60. 2003..The weaning protocol introduced in this study demonstrates the benefits of using a collaborative team to identify best practices and implement them in a practice setting...
Chlorhexidine, toothbrushing, and preventing ventilator-associated pneumonia in critically ill adultsCindy L Munro
Adult Health Department, School of Nursing, Virginia Commonwealth University, Richmond, Virginia 23298 0567, USA
Am J Crit Care 18:428-37; quiz 438. 2009..Ventilator-associated pneumonia is associated with increased morbidity and mortality...
Are corticosteroids useful in late-stage acute respiratory distress syndrome?Curtis N Sessler
Division of Pulmonary and Critical Care, Virginia Commonwealth University Health System, Medical College of Virginia Hospitals, Richmond, Virginia 23298, USA
Respir Care 55:43-55. 2010..If corticosteroids are administered, infection surveillance, avoidance of neuromuscular blockers, and gradual taper of corticosteroids are recommended...
Actigraphy in the critically ill: correlation with activity, agitation, and sedationMary Jo Grap
Adult Health Department of the School of Nursing, Virginia Commonwealth University Health System, Richmond, VA, USA
Am J Crit Care 14:52-60. 2005..Actigraphy may become particularly important as a continuous measurement of activity for use in behavioral research and may enhance early recognition and management of the excessive activity that characterizes agitation...
Sedation, analgesia, and neuromuscular blockade for high-frequency oscillatory ventilationCurtis N Sessler
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, USA
Crit Care Med 33:S209-16. 2005..CONCLUSIONS: A multidisciplinary, structured approach that is based on the considerations described should help achieve optimal results in this challenging patient population...
Severe hypoxemic respiratory failure: part 2--nonventilatory strategiesSuhail Raoof
Division of Pulmonary and Critical Care Medicine, New York Methodist Hospital, 506 Sixth St, Brooklyn, NY 11215, USA
Chest 137:1437-48. 2010..These interventions may be considered for use, particularly for cases of refractory severe hypoxemia, with proper appreciation of potential costs and adverse effects...
Are there benefits or harm from pressure targeting during lung-protective ventilation?Neil R MacIntyre
Division of Pulmonary and Critical Care Medicine, Duke University Hospital, Box 3911, Durham NC 27710, USA
Respir Care 55:175-80; discussion 180-3. 2010..Indeed, as is often the case in managing complex life-support devices, it is operator expertise rather than the device design features that most impacts patient outcomes...
Severe hypoxemic respiratory failure: part 1--ventilatory strategiesAdebayo Esan
Division of Pulmonary and Critical Care Medicine, New York Methodist Hospital, 506 Sixth St, Brooklyn, NY 11215, USA
Chest 137:1203-16. 2010..Which, if any, of these approaches should be used is often determined by the availability of equipment and clinician bias...
Alcohol-use disorders in the critically ill patientMarjolein de Wit
Division of Pulmonary Disease and Critical Care Medicine, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA 23298 0050, USA
Chest 138:994-1003. 2010..AUDs are underdiagnosed, and a first step to improving patient outcomes may lie in systematically and accurately identifying AUDs...
Effects of platelet-activating factor antagonist SRI 63-441 on endotoxemia in sheepC N Sessler
Department of Medicine, Medical College of Virginia, Richmond
J Appl Physiol 65:2624-31. 1988..8 +/- 1.1 to 14.1 +/- 8.0 (P less than 0.05) and 12.7 +/- 8.6 ml/h at 1 and 4 h, respectively. SRI 63-441 abolished the early and attenuated the late increase in QL.(ABSTRACT TRUNCATED AT 250 WORDS)..
Effect of backrest elevation on the development of ventilator-associated pneumoniaMary Jo Grap
The Adult Health Department of the School of Nursing
Am J Crit Care 14:325-32; quiz 333. 2005..CONCLUSIONS: Subjects spent the majority of the time at backrest elevations less than 30 degrees . Only the combination of early, low backrest elevation and severity of illness affected the incidence of ventilator-associated pneumonia...
Sedation scales in the ICUCurtis N Sessler
Chest 126:1727-30. 2004
Monitoring sedation status over time in ICU patients: reliability and validity of the Richmond Agitation-Sedation Scale (RASS)E Wesley Ely
Department of Medicine, Center for Health Services Research, Vanderbilt University School of Medicine, Tennessee Valley Veteran s Affairs Healthcare System, Geriatric Research Education and Clinical Center, Nashville 37232, USA
JAMA 289:2983-91. 2003....
Duration of action of a single, early oral application of chlorhexidine on oral microbial flora in mechanically ventilated patients: a pilot studyMary Jo Grap
Adult Health Department of the School of Nursing, Virginia Commonwealth University, Richmond 23298-0567, USA
Heart Lung 33:83-91. 2004..17 to 5.57). CONCLUSIONS: Trends in the data suggest that use of chlorhexidine gluconate in the early post-intubation period may mitigate or delay the development of ventilator-associated pneumonia...
The critical care crisis in the United States: a report from the professionMark A Kelley
Department of Medicine, Henry Ford Hospital, Detroit, MI 48202, USA
Chest 125:1514-7. 2004
Wake up and breatheCurtis N Sessler
Crit Care Med 32:1413-4. 2004
Endotracheal tube narrowing during mechanical ventilationCurtis N Sessler
Crit Care Med 32:1979-80. 2004
Train-of-four to monitor neuromuscular blockade?Curtis N Sessler
Chest 126:1018-22. 2004
The Critical Care Family Assistance Program: caring for those who careCurtis N Sessler
Chest 128:1101-3. 2005
