HARVEY ALLEN SCHENKEIN

Summary

Affiliation: Virginia Commonwealth University
Country: USA

Publications

  1. doi request reprint Inflammatory mechanisms linking periodontal diseases to cardiovascular diseases
    Harvey A Schenkein
    Department of Periodontics, Virginia Commonwealth University, Richmond, VA, USA
    J Clin Periodontol 40:S51-69. 2013
  2. pmc Anti-cardiolipin from periodontitis patients induces MCP-1 production by human umbilical vein endothelial cells
    Harvey A Schenkein
    Department of Periodontics, School of Dentistry, Virginia Commonwealth University, Richmond, VA 23298 0566, USA
    J Clin Periodontol 40:212-7. 2013
  3. doi request reprint Birth weight of infants of mothers with aggressive periodontitis
    Harvey A Schenkein
    Department of Periodontics, Virginia Commonwealth University, School of Dentistry, Richmond, VA 23298 0566, USA
    J Periodontol 83:279-86. 2012
  4. pmc IL-17 in sera from patients with aggressive periodontitis
    H A Schenkein
    Department of Periodontics, School of Dentistry, Virginia Commonwealth University, Richmond, VA 23298 0566, USA
    J Dent Res 89:943-7. 2010
  5. ncbi request reprint Anti-cardiolipin antibodies in sera from patients with periodontitis
    H A Schenkein
    Clinical Research Center for Periodontal Disease, Virginia Commonwealth University, School of Dentistry, PO Box 980566, Richmond, VA 23298 0566, USA
    J Dent Res 82:919-22. 2003
  6. ncbi request reprint Locally produced anti-phosphorylcholine and anti-oxidized low-density lipoprotein antibodies in gingival crevicular fluid from aggressive periodontitis patients
    Harvey A Schenkein
    Virginia Commonwealth University School of Dentistry, Clinical Research Center for Periodontal Disease, Richmond, VA 23298 0566, USA
    J Periodontol 75:146-53. 2004
  7. ncbi request reprint Anti-cardiolipin and increased serum adhesion molecule levels in patients with aggressive periodontitis
    Harvey A Schenkein
    Clinical Research Center for Periodontal Disease, Virginia Commonwealth University School of Dentistry, Richmond, VA 23298, USA
    J Periodontol 78:459-66. 2007
  8. ncbi request reprint Cytokines and inflammatory factors regulating immunoglobulin production in aggressive periodontitis
    Harvey A Schenkein
    Department of Periodontics, Virginia Commonwealth University, School of Dentistry, Richmond, VA, USA
    Periodontol 2000 45:113-27. 2007
  9. pmc Endocarditis-associated oral streptococci promote rapid differentiation of monocytes into mature dendritic cells
    Chin Lo Hahn
    Department of Endodontics, School of Dentistry, Lyons Building, Rm 322, 520 N 12th Street, P O Box 980566, Richmond, VA 23298 0566, USA
    Infect Immun 73:5015-21. 2005
  10. pmc Monocyte differentiation in localized juvenile periodontitis is skewed toward the dendritic cell phenotype
    Suzanne E Barbour
    Department of Microbiology and Immunology, Virginia Commonwealth University School of Dentistry, Richmond, Virginia 23298 0678, USA
    Infect Immun 70:2780-6. 2002

Research Grants

Collaborators

Detail Information

Publications21

  1. doi request reprint Inflammatory mechanisms linking periodontal diseases to cardiovascular diseases
    Harvey A Schenkein
    Department of Periodontics, Virginia Commonwealth University, Richmond, VA, USA
    J Clin Periodontol 40:S51-69. 2013
    ..In this article, inflammatory mechanisms that link periodontal diseases to cardiovascular diseases are reviewed...
  2. pmc Anti-cardiolipin from periodontitis patients induces MCP-1 production by human umbilical vein endothelial cells
    Harvey A Schenkein
    Department of Periodontics, School of Dentistry, Virginia Commonwealth University, Richmond, VA 23298 0566, USA
    J Clin Periodontol 40:212-7. 2013
    ..We sought to determine if anti-cardiolipin antibodies from periodontitis patients induced monocyte chemotactic protein-1 production by human vascular endothelial cells...
  3. doi request reprint Birth weight of infants of mothers with aggressive periodontitis
    Harvey A Schenkein
    Department of Periodontics, Virginia Commonwealth University, School of Dentistry, Richmond, VA 23298 0566, USA
    J Periodontol 83:279-86. 2012
    ..It was hypothesized that if periodontal infections predispose low birth weights and premature birth, then such outcomes should be apparent when the mother has aggressive periodontitis (AgP)...
  4. pmc IL-17 in sera from patients with aggressive periodontitis
    H A Schenkein
    Department of Periodontics, School of Dentistry, Virginia Commonwealth University, Richmond, VA 23298 0566, USA
    J Dent Res 89:943-7. 2010
    ..Therefore, Th17 responses may be characteristic of AgP, and IL-17 may play a role in the pathogenesis of aggressive periodontitis...
  5. ncbi request reprint Anti-cardiolipin antibodies in sera from patients with periodontitis
    H A Schenkein
    Clinical Research Center for Periodontal Disease, Virginia Commonwealth University, School of Dentistry, PO Box 980566, Richmond, VA 23298 0566, USA
    J Dent Res 82:919-22. 2003
    ..These antibodies could be involved in elevated risk for stroke, atherosclerosis, or pre-term birth in periodontitis patients...
  6. ncbi request reprint Locally produced anti-phosphorylcholine and anti-oxidized low-density lipoprotein antibodies in gingival crevicular fluid from aggressive periodontitis patients
    Harvey A Schenkein
    Virginia Commonwealth University School of Dentistry, Clinical Research Center for Periodontal Disease, Richmond, VA 23298 0566, USA
    J Periodontol 75:146-53. 2004
    ..We hypothesized that, if the oral flora is a source of PC antigens, then we should be able to detect local anti-PC and anti-oxLDL production in gingival crevicular fluid (GCF)...
  7. ncbi request reprint Anti-cardiolipin and increased serum adhesion molecule levels in patients with aggressive periodontitis
    Harvey A Schenkein
    Clinical Research Center for Periodontal Disease, Virginia Commonwealth University School of Dentistry, Richmond, VA 23298, USA
    J Periodontol 78:459-66. 2007
    ..Anti-CL is known to promote vascular inflammation and thrombosis...
  8. ncbi request reprint Cytokines and inflammatory factors regulating immunoglobulin production in aggressive periodontitis
    Harvey A Schenkein
    Department of Periodontics, Virginia Commonwealth University, School of Dentistry, Richmond, VA, USA
    Periodontol 2000 45:113-27. 2007
  9. pmc Endocarditis-associated oral streptococci promote rapid differentiation of monocytes into mature dendritic cells
    Chin Lo Hahn
    Department of Endodontics, School of Dentistry, Lyons Building, Rm 322, 520 N 12th Street, P O Box 980566, Richmond, VA 23298 0566, USA
    Infect Immun 73:5015-21. 2005
    ..These data suggest that the initiation of bacterial endocarditis by oral streptococci may involve monocyte-to-DC differentiation, and this may help explain the low levels of macrophages in the site...
  10. pmc Monocyte differentiation in localized juvenile periodontitis is skewed toward the dendritic cell phenotype
    Suzanne E Barbour
    Department of Microbiology and Immunology, Virginia Commonwealth University School of Dentistry, Richmond, Virginia 23298 0678, USA
    Infect Immun 70:2780-6. 2002
    ....
  11. ncbi request reprint Antibody reactive with Porphyromonas gingivalis hemagglutinin in chronic and generalized aggressive periodontitis
    Joseph V Califano
    Department of Periodontics, School of Dentistry, Virginia Commonwealth University, Richmond, VA 23298 0566, USA
    J Periodontal Res 39:263-8. 2004
    ..Recent studies in the murine abscess model and in the host antibody response in chronic periodontitis patients suggest that antibody reactive with P. gingivalis hemagglutinin may be an important protective antibody response...
  12. ncbi request reprint Differential expression of platelet-activating factor acetylhydrolase in macrophages and monocyte-derived dendritic cells
    Salma Al-Darmaki
    Clinical Research Center for Periodontal Diseases, Virginia Commonwealth University School of Dentistry, Richmond, VA 23298, USA
    J Immunol 170:167-73. 2003
    ..In contrast, Mphi did not respond in this manner. Together, these data indicate that PAF metabolism may impinge on regulation of the immune response by regulating the accessory activity of MDDC...
  13. pmc Opsonization of Actinobacillus actinomycetemcomitans by immunoglobulin G antibody reactive with phosphorylcholine
    Donald Purkall
    Clinical Research Center for Periodontal Disease, School of Dentistry, Virginia Commonwealth University, Richmond, Virginia 23298, USA
    Infect Immun 70:6485-8. 2002
    ..actinomycetemcomitans in the absence of complement, implying that anti-PC may be a protective antibody against such strains of bacteria...
  14. ncbi request reprint Prostaglandin E2-mediated regulation of immunoglobulin G2 via interferon gamma
    Shigehisa Tanaka
    Clinical Research Center for Periodontal Diseases, Virginia Commonwealth University School of Dentistry, Richmond, VA, USA
    J Periodontol 74:771-9. 2003
    ..This unusual relationship prompted the hypothesis that, in certain circumstances, PGE2 enhances rather than inhibits IFN-gamma production...
  15. pmc Delineation of the role of platelet-activating factor in the immunoglobulin G2 antibody response
    Salma Al-Darmaki
    Clinical Research Center for Periodontal Diseases, Virginia Commonwealth University, Richmond, Virginia, USA
    Clin Diagn Lab Immunol 11:720-8. 2004
    ..As IgG2 antibodies opsonize oral bacteria and promote their clearance and destruction, these alterations in PAF metabolism may be essential for limiting disease severity in LAgP patients...
  16. ncbi request reprint C-reactive protein levels in patients with aggressive periodontitis
    Trang N Salzberg
    Department of Periodontics, School of Dentistry, Virginia Commonwealth University, Richmond, 23298 0566, USA
    J Periodontol 77:933-9. 2006
    ..The purpose of this study was to determine the relative levels of serum CRP in AgP patients and periodontally healthy subjects and to examine patients' characteristics that might account for intergroup differences...
  17. ncbi request reprint Clinical crown length of the maxillary anterior teeth preorthodontics and postorthodontics
    Bryan M Konikoff
    Department of Periodontics, Virginia Commonwealth University School of Dentistry, Richmond, USA
    J Periodontol 78:645-53. 2007
    ..By studying the size relationship of the clinical crowns of teeth, in an orthodontic population, we can begin to quantify their need for periodontal plastic surgery...
  18. ncbi request reprint Host responses in maintaining periodontal health and determining periodontal disease
    Harvey A Schenkein
    Department of Peridontics, Virginia Commonwealth University VCU MCV, Richmond, Virginia, USA
    Periodontol 2000 40:77-93. 2006
  19. ncbi request reprint Altered lipoprotein subclass distribution and PAF-AH activity in subjects with generalized aggressive periodontitis
    Miguel L Rufail
    Department of Biochemistry, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 23298, USA
    J Lipid Res 46:2752-60. 2005
    ..These differences may help explain the increased risk of GAgP subjects for cardiovascular disease...
  20. ncbi request reprint Quantitative measures of aggressive periodontitis show substantial heritability and consistency with traditional diagnoses
    Scott R Diehl
    Center for Pharmacogenomics and Complex Disease Research, New Jersey Dental School, UMDNJ, Newark, NJ 07101, USA
    J Periodontol 76:279-88. 2005
    ..Since AL is continuous and quantitative, however, useful information is lost. We developed quantitative measures of AgP, compared these to traditional methods, and estimated heritabilities in families...
  21. ncbi request reprint Finding genetic risk factors for periodontal diseases: is the climb worth the view?
    Harvey A Schenkein
    Periodontol 2000 30:79-90. 2002

Research Grants3