THOMAS REEVES

Summary

Affiliation: Virginia Commonwealth University
Country: USA

Publications

  1. pmc Unmyelinated axons show selective rostrocaudal pathology in the corpus callosum after traumatic brain injury
    Thomas M Reeves
    Department of Anatomy and Neurobiology, 1217 E Marshall St, Room 740, MCVCampus Box 980709, Virginia Commonwealth University, Richmond, VA 23298, USA
    J Neuropathol Exp Neurol 71:198-210. 2012
  2. ncbi request reprint Myelinated and unmyelinated axons of the corpus callosum differ in vulnerability and functional recovery following traumatic brain injury
    Thomas M Reeves
    Department of Anatomy and Neurobiology, Medical College of Virginia Campus, Virginia Commonwealth University, 1217 E Marshall Street, Room 740, MCV Campus Box 980709, Richmond, VA 23298, USA
    Exp Neurol 196:126-37. 2005
  3. pmc Preferential neuroprotective effect of tacrolimus (FK506) on unmyelinated axons following traumatic brain injury
    Thomas M Reeves
    Department of Anatomy and Neurobiology, 1217 E Marshall Street, Room 740, Medical Campus Box 980709, Virginia Commonwealth University, Richmond, VA 23298, USA
    Brain Res 1154:225-36. 2007
  4. pmc Proteolysis of submembrane cytoskeletal proteins ankyrin-G and αII-spectrin following diffuse brain injury: a role in white matter vulnerability at Nodes of Ranvier
    Thomas M Reeves
    Department of Anatomy and Neurobiology, School of Medicine, Virginia Commonwealth University Medical Center, Richmond, VA, USA
    Brain Pathol 20:1055-68. 2010
  5. pmc The effects of cyclosporin-A on axonal conduction deficits following traumatic brain injury in adult rats
    Beverly S Colley
    Department of Anatomy and Neurobiology, School of Medicine, Virginia Commonwealth University Medical Center, Richmond, VA 23298, USA
    Exp Neurol 224:241-51. 2010
  6. pmc Agrin expression during synaptogenesis induced by traumatic brain injury
    M Cristina Falo
    Department of Anatomy and Neurobiology, School of Medicine, Virginia Commonwealth University Medical Center, Richmond, Virginia 23298, USA
    J Neurotrauma 25:769-83. 2008
  7. ncbi request reprint Matrix metalloproteinase inhibition alters functional and structural correlates of deafferentation-induced sprouting in the dentate gyrus
    Thomas M Reeves
    Department of Anatomy and Neurobiology, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23298, USA
    J Neurosci 23:10182-9. 2003
  8. ncbi request reprint Concurrent monitoring of cerebral electrophysiology and metabolism after traumatic brain injury: an experimental and clinical study
    Oscar L Alves
    Department of Neurosurgery, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, 23298, USA
    J Neurotrauma 22:733-49. 2005
  9. pmc Injury modality, survival interval, and sample region are critical determinants of qRT-PCR reference gene selection during long-term recovery from brain trauma
    Janna L Harris
    Department of Anatomy and Neurobiology, School of Medicine, Virginia Commonwealth University Medical Center, Richmond, Virginia 23298, USA
    J Neurotrauma 26:1669-81. 2009

Collaborators

Detail Information

Publications9

  1. pmc Unmyelinated axons show selective rostrocaudal pathology in the corpus callosum after traumatic brain injury
    Thomas M Reeves
    Department of Anatomy and Neurobiology, 1217 E Marshall St, Room 740, MCVCampus Box 980709, Virginia Commonwealth University, Richmond, VA 23298, USA
    J Neuropathol Exp Neurol 71:198-210. 2012
    ..The finding of a preferential vulnerability in unmyelinated axons has implications for current concepts of axonal responses after TBI and for development of specifically targeted therapies...
  2. ncbi request reprint Myelinated and unmyelinated axons of the corpus callosum differ in vulnerability and functional recovery following traumatic brain injury
    Thomas M Reeves
    Department of Anatomy and Neurobiology, Medical College of Virginia Campus, Virginia Commonwealth University, 1217 E Marshall Street, Room 740, MCV Campus Box 980709, Richmond, VA 23298, USA
    Exp Neurol 196:126-37. 2005
    ..Collectively, these findings demonstrate differential vulnerabilities of axons to brain injury and suggest that damage to unmyelinated fibers may play a significant role in morbidity associated with brain injury...
  3. pmc Preferential neuroprotective effect of tacrolimus (FK506) on unmyelinated axons following traumatic brain injury
    Thomas M Reeves
    Department of Anatomy and Neurobiology, 1217 E Marshall Street, Room 740, Medical Campus Box 980709, Virginia Commonwealth University, Richmond, VA 23298, USA
    Brain Res 1154:225-36. 2007
    ..Collectively, these studies further substantiate a distinctive role of unmyelinated axons in TAI, and suggest a highly efficacious neuroprotective strategy to target this axonal population...
  4. pmc Proteolysis of submembrane cytoskeletal proteins ankyrin-G and αII-spectrin following diffuse brain injury: a role in white matter vulnerability at Nodes of Ranvier
    Thomas M Reeves
    Department of Anatomy and Neurobiology, School of Medicine, Virginia Commonwealth University Medical Center, Richmond, VA, USA
    Brain Pathol 20:1055-68. 2010
    ..The time course of such changes were comparable to previously observed functional deficits in callosal fibers...
  5. pmc The effects of cyclosporin-A on axonal conduction deficits following traumatic brain injury in adult rats
    Beverly S Colley
    Department of Anatomy and Neurobiology, School of Medicine, Virginia Commonwealth University Medical Center, Richmond, VA 23298, USA
    Exp Neurol 224:241-51. 2010
    ..The present findings also support growing evidence that myelinated and unmyelinated axons respond differentially to injury and neuroprotective compounds...
  6. pmc Agrin expression during synaptogenesis induced by traumatic brain injury
    M Cristina Falo
    Department of Anatomy and Neurobiology, School of Medicine, Virginia Commonwealth University Medical Center, Richmond, Virginia 23298, USA
    J Neurotrauma 25:769-83. 2008
    ..Further, when pathogenic conditions which induce synaptic plasticity are reduced, increase in agrin mRNA is attenuated...
  7. ncbi request reprint Matrix metalloproteinase inhibition alters functional and structural correlates of deafferentation-induced sprouting in the dentate gyrus
    Thomas M Reeves
    Department of Anatomy and Neurobiology, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23298, USA
    J Neurosci 23:10182-9. 2003
    ..These results establish a role for MMP-dependent processes in the deafferentation/sprouting cycle...
  8. ncbi request reprint Concurrent monitoring of cerebral electrophysiology and metabolism after traumatic brain injury: an experimental and clinical study
    Oscar L Alves
    Department of Neurosurgery, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, 23298, USA
    J Neurotrauma 22:733-49. 2005
    ..The results suggest that this technique provides a functional monitoring capability which cannot be obtained when electrophysiology is measured with surface or epidural EEG alone...
  9. pmc Injury modality, survival interval, and sample region are critical determinants of qRT-PCR reference gene selection during long-term recovery from brain trauma
    Janna L Harris
    Department of Anatomy and Neurobiology, School of Medicine, Virginia Commonwealth University Medical Center, Richmond, Virginia 23298, USA
    J Neurotrauma 26:1669-81. 2009
    ..As previously concluded for acute post-injury intervals, we stress the importance of reference gene validation for each brain injury paradigm and each set of experimental conditions...

Research Grants4

  1. Axolemmal molecular domains and unmyelinated fiber vulnerability in TBI
    THOMAS REEVES; Fiscal Year: 2007
    ..Neuroprotective drugs are also used to alter the course of the functional and structural effects of injury. ..
  2. Axolemmal molecular domains and unmyelinated fiber vulnerability in TBI
    Thomas M Reeves; Fiscal Year: 2010
    ..Neuroprotective drugs are also used to alter the course of the functional and structural effects of injury. ..