J M Pellock

Summary

Affiliation: Virginia Commonwealth University
Country: USA

Publications

  1. ncbi request reprint Managing behavioral and cognitive problems in children with epilepsy
    John M Pellock
    Division of Child Neurology, Department of Neurology, Virginia Commonwealth University, Medical College of Virginia, 1001 East Marshall Street, 1st Floor, Richmond, VA 23298, USA
    J Child Neurol 19:S73-4. 2004
  2. ncbi request reprint Which seizure-precipitating factors do patients with epilepsy most frequently report?
    Karl O Nakken
    National Centre for Epilepsy, Sandvika, Norway
    Epilepsy Behav 6:85-9. 2005
  3. ncbi request reprint Overview: definitions and classifications of seizure emergencies
    John M Pellock
    Division of Child Neurology, Virginia Commonwealth University, School of Medicine Richmond, VA 23298 0211, USA jpellock hsc vcu edu
    J Child Neurol 22:9S-13S. 2007
  4. ncbi request reprint Update on the epidemiology and prognosis of pediatric epilepsy
    Shlomo Shinnar
    Montefiore Medical Center, and the Albert Einstein College of Medicine, Bronx, NY 10467, USA
    J Child Neurol 17:S4-17. 2002
  5. ncbi request reprint Felbamate in epilepsy therapy: evaluating the risks
    J M Pellock
    Division of Child Neurology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298, USA
    Drug Saf 21:225-39. 1999
  6. ncbi request reprint Safety of Diastat, a rectal gel formulation of diazepam for acute seizure treatment
    John M Pellock
    Virginia Commonwealth University, Medical College of Virginia, Richmond, Virginia 23298, USA
    Drug Saf 27:383-92. 2004
  7. ncbi request reprint Time to treatment in prolonged seizure episodes
    John M Pellock
    Department of Neurology, Virginia Commonwealth University, Medical College of Virginia, Richmond, VA, USA
    Epilepsy Behav 5:192-6. 2004
  8. ncbi request reprint Defining the problem: psychiatric and behavioral comorbidity in children and adolescents with epilepsy
    John M Pellock
    Division of Child Neurology, Department of Neurology, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 23298, USA
    Epilepsy Behav 5:S3-9. 2004
  9. ncbi request reprint Acute pancreatitis coincident with valproate use: a critical review
    John M Pellock
    Virginia Commonwealth University Health Systems Medical College of Virginia Hospitals, Richmond, Virginia 23298, USA
    Epilepsia 43:1421-4. 2002
  10. ncbi request reprint The challenge of neuropsychiatric issues in pediatric epilepsy
    John M Pellock
    Division of Child Neurology, Department of Neurology, Virginia Commonwealth University, Medical College of Virginia, 1001 East Marshall Street, 1st Floor, Richmond, VA 23298, USA
    J Child Neurol 19:S1-5. 2004

Detail Information

Publications37

  1. ncbi request reprint Managing behavioral and cognitive problems in children with epilepsy
    John M Pellock
    Division of Child Neurology, Department of Neurology, Virginia Commonwealth University, Medical College of Virginia, 1001 East Marshall Street, 1st Floor, Richmond, VA 23298, USA
    J Child Neurol 19:S73-4. 2004
  2. ncbi request reprint Which seizure-precipitating factors do patients with epilepsy most frequently report?
    Karl O Nakken
    National Centre for Epilepsy, Sandvika, Norway
    Epilepsy Behav 6:85-9. 2005
    ....
  3. ncbi request reprint Overview: definitions and classifications of seizure emergencies
    John M Pellock
    Division of Child Neurology, Virginia Commonwealth University, School of Medicine Richmond, VA 23298 0211, USA jpellock hsc vcu edu
    J Child Neurol 22:9S-13S. 2007
    ..The importance of timely intervention in generalized tonic-clonic status epilepticus must be emphasized. Recent research has found that emergency department personnel fail to recognize the condition in children in 34% of cases...
  4. ncbi request reprint Update on the epidemiology and prognosis of pediatric epilepsy
    Shlomo Shinnar
    Montefiore Medical Center, and the Albert Einstein College of Medicine, Bronx, NY 10467, USA
    J Child Neurol 17:S4-17. 2002
    ..This review summarizes recent data on the epidemiology and prognosis of pediatric epilepsy...
  5. ncbi request reprint Felbamate in epilepsy therapy: evaluating the risks
    J M Pellock
    Division of Child Neurology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298, USA
    Drug Saf 21:225-39. 1999
    ..With monitoring, patient education, and continued research to further elucidate risk factors, felbamate can be a viable therapeutic agent for patients with epilepsy...
  6. ncbi request reprint Safety of Diastat, a rectal gel formulation of diazepam for acute seizure treatment
    John M Pellock
    Virginia Commonwealth University, Medical College of Virginia, Richmond, Virginia 23298, USA
    Drug Saf 27:383-92. 2004
    ..Under-administration may be a serious safety issue because of morbidity that may result if seizures are not terminated. Chronic administration may cause tachyphylaxis and should be avoided...
  7. ncbi request reprint Time to treatment in prolonged seizure episodes
    John M Pellock
    Department of Neurology, Virginia Commonwealth University, Medical College of Virginia, Richmond, VA, USA
    Epilepsy Behav 5:192-6. 2004
    ..This baseline study supports the need for patient education regarding seizure emergencies and wider availability of at-home treatment options to shorten time to seizure treatment...
  8. ncbi request reprint Defining the problem: psychiatric and behavioral comorbidity in children and adolescents with epilepsy
    John M Pellock
    Division of Child Neurology, Department of Neurology, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 23298, USA
    Epilepsy Behav 5:S3-9. 2004
    ..Comorbid conditions in children and adolescents with epilepsy should be evaluated and treated as soon as they are recognized...
  9. ncbi request reprint Acute pancreatitis coincident with valproate use: a critical review
    John M Pellock
    Virginia Commonwealth University Health Systems Medical College of Virginia Hospitals, Richmond, Virginia 23298, USA
    Epilepsia 43:1421-4. 2002
    ..We reviewed cases of pancreatitis in VPA-treated patients from the clinical database of VPA/divalproex trials and compared the incidence of elevated amylase levels between VPA- and placebo-treated patients...
  10. ncbi request reprint The challenge of neuropsychiatric issues in pediatric epilepsy
    John M Pellock
    Division of Child Neurology, Department of Neurology, Virginia Commonwealth University, Medical College of Virginia, 1001 East Marshall Street, 1st Floor, Richmond, VA 23298, USA
    J Child Neurol 19:S1-5. 2004
    ..Antiepileptic drugs are often blamed for cognitive or behavioral problems in children treated for epilepsy, but the actual contribution to such problems in a particular child can be difficult to ascertain...
  11. ncbi request reprint Respiratory adverse events associated with diazepam rectal gel
    John M Pellock
    Department of Neurology, Virginia Commonwealth University, Medical College of Virginia, Richmond 23298 0211, USA
    Neurology 64:1768-70. 2005
    ..The deaths occurred in the context of a prolonged seizure and respiratory depression was not the main symptom. When used as recommended, diazepam rectal gel has a low rate of serious morbidity or mortality...
  12. ncbi request reprint Myoclonic epilepsies: syndromes and their treatment
    John M Pellock
    Division of Child Neurology, Department of Neurology, Virginia Commonwealth University, Medical College of Virginia, Richmond, VA 23298, USA
    Suppl Clin Neurophysiol 57:425-32. 2004
  13. ncbi request reprint Felbamate: consensus of current clinical experience
    John M Pellock
    Virginia Commonwealth University, Medical College of Virginia, PO Box 980211, 1001 E Marshall St, 1st Floor, Richmond, VA 23298, USA
    Epilepsy Res 71:89-101. 2006
    ..This review of clinical data and discussion of the current understanding of the risk:benefit of felbamate therapy supports its use as an important therapeutic option for some patients with refractory epilepsy...
  14. ncbi request reprint Extended-release formulations: simplifying strategies in the management of antiepileptic drug therapy
    John M Pellock
    Division of Child Neurology, Virginia Commonwealth University, Medical College of Virginia, PO Box 980211 VCU MCV, Richmond, VA 23298 0211, USA
    Epilepsy Behav 5:301-7. 2004
    ..These same attributes of extended-release formulations may also improve compliance, quality of life, and patient satisfaction with treatment...
  15. ncbi request reprint Short-term outcomes of children with febrile status epilepticus
    S Shinnar
    Department of Neurology, Montefiore Medical Center, Albert Einstein College of Medicine, 111 E. 210th Street, Bronx, NY 10467, USA
    Epilepsia 42:47-53. 2001
    ..Long-term follow-up of this cohort may provide insight into the relationship of prolonged febrile seizures and subsequent mesial temporal sclerosis...
  16. ncbi request reprint Rapid infusion with valproate sodium is well tolerated in patients with epilepsy
    J W Wheless
    Department of Neurology, University of Texas Health Science Center, Houston, USA
    Neurology 63:1507-8. 2004
    ..Valproate sodium had no clinically significant negative effects on blood pressure and pulse rate and caused only mild-to-moderate, reversible adverse events...
  17. ncbi request reprint Managing pediatric epilepsy syndromes with new antiepileptic drugs
    J M Pellock
    Division of Child Neurology, Medical College of Virginia of Virginia Commonwealth University, Richmond, Virginia 23298 0211, USA
    Pediatrics 104:1106-16. 1999
    ..To most effectively treat children with epilepsy syndromes, further research must be completed to validate the positive effects described in case reports, open-label clinical trials, and early controlled clinical trials...
  18. ncbi request reprint Tiagabine (gabitril) experience in children
    J M Pellock
    Medical College of Virginia of Virginia Commonwealth University, 307 College Street, Richmond, VA 23219, U S A
    Epilepsia 42:49-51. 2001
    ..In summary, preliminary pediatric data with TGB suggest particular efficacy against epilepsy characterized by partial seizures or other syndromes, and further investigation is warranted...
  19. ncbi request reprint Pharmacokinetic study of levetiracetam in children
    J M Pellock
    Division of Child Neurology, Medical College of Virginia of Virginia Commonwealth University, Richmond, Virginia 23298 0211, USA
    Epilepsia 42:1574-9. 2001
    ..The pharmacokinetics of the novel antiepileptic drug (AED) levetiracetam and its major metabolite, ucb L057, were studied in children with partial seizures in a multicenter, open-label, single-dose study...
  20. ncbi request reprint Utility of electroencephalography in the pediatric emergency department
    F K Alehan
    Division of Child Neurology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298-0211, USA
    J Child Neurol 16:484-7. 2001
    ..Thus, a prompt EEG should be considered in children with new-onset seizures and unexplained altered consciousness...
  21. ncbi request reprint Overview of childhood epilepsy and epileptic syndromes and advances in therapy
    L D Morton
    Virginia Commonwealth University Medical College of Virginia, Division of Child Neurology, Richmond 23298 0211, USA
    Curr Pharm Des 6:879-900. 2000
    ..Efficacy data and toxicity are discussed from both the adult, and when available, pediatric data...
  22. doi request reprint Vigabatrin 35 years later - from mechanism of action to benefit-risk considerations
    W D Shields
    Division of Pediatric Neurology, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA, USA Department of Neurology, Virginia Commonwealth University, Richmond, VA, USA
    Acta Neurol Scand Suppl 192:1-4. 2011
    ..Shields WD, Pellock JM. Vigabatrin 35 years later - from mechanism of action to benefit-risk considerations. Acta Neurol Scand: 2011: 124 (Suppl. 192): 1-4. © 2011 John Wiley & Sons A/S...
  23. ncbi request reprint Encephalopathy as the presenting symptom of Hashimoto's thyroiditis
    N Watemberg
    Child Neurology Division, Medical College of Virginia, Virginia Commonwealth University, Richmond, USA
    J Child Neurol 15:66-9. 2000
    ..We describe the case of a child in whom acute encephalopathy was the presenting symptom of Hashimoto's thyroiditis...
  24. ncbi request reprint Understanding co-morbidities affecting children with epilepsy
    John M Pellock
    Virginia Commonwealth University Medical College of Virginia, Richmond, VA 23298 0565, USA
    Neurology 62:S17-23. 2004
    ..Newer AEDs, such as lamotrigine, topiramate, gabapentin, oxcarbazepine, and tiagabine, may benefit children with epilepsy and some co-morbid disorders...
  25. ncbi request reprint Safety of rapid intravenous valproate infusion in pediatric patients
    Lawrence D Morton
    Division of Child Neurology, Department of Pharmacy, Virginia Commonwealth University, Richmond, Virginia 23298 0211, USA
    Pediatr Neurol 36:81-3. 2007
    ..No abnormal laboratory results were reported. Rapid intravenous valproate infusion appears to be safe in pediatric patients...
  26. ncbi request reprint Analyzing the etiology of benign rolandic epilepsy: a multicenter twin collaboration
    Lata Vadlamudi
    Epilepsy Research Centre, Department of Medicine Neurology, University of Melbourne, Austin Health, Heidelberg, Victoria, Australia
    Epilepsia 47:550-5. 2006
    ..We analyzed a large sample of twins from four international twin registers to probe the genetics of BRE. We also aim to synthesize the apparently conflicting family and twin data into a model of BRE etiology...
  27. ncbi request reprint The trials and tribulations of pediatric drug trials
    Shlomo Shinnar
    Neurology 65:1348-9. 2005
  28. ncbi request reprint Antiepileptic drugs: expanded options and improved tolerance
    David J Leszczyszyn
    Division of Child Neurology, Department of Neurology, Virginia Commonwealth University School of Medicine, Richmond, Virginia 23298 0211, USA
    Am J Electroneurodiagnostic Technol 44:75-94. 2004
    ..Fortunately the latter problems are limited in this recent generation of drugs and their broad spectrum of action is leading to improved seizure control and better quality of life for our patients...
  29. ncbi request reprint Genetic factors in seizures: a population-based study of 47,626 US, Norwegian and Danish twin pairs
    Marianne J Kjeldsen
    The Danish Twin Registry, Epidemiology, Institute of Public Health, University of Southern Denmark, Odense, Denmark
    Twin Res Hum Genet 8:138-47. 2005
    ..This sample is likely to provide an important resource for studying the genetics of epilepsy subtypes and febrile seizures...
  30. ncbi request reprint Efficacy and safety of levetiracetam in children with partial seizures: an open-label trial
    Tracy A Glauser
    Department of Neurology, Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Epilepsia 43:518-24. 2002
    ..To assess the efficacy and safety of levetiracetam (LEV) as adjunctive therapy in children with treatment-resistant partial-onset seizures...
  31. ncbi request reprint Zonisamide: physician and patient experiences
    Anthony Marmarou
    International Epilepsy Consortium, Virginia Commonwealth University Medical Center, Old City Hall, 1001 E Broad Street, Suite 235, P O Box 980449, Richmond, VA 23298, USA
    Epilepsy Res 64:63-9. 2005
    ..6% (45/84), 58.8% (50/85), and 62.1% (54/87) of patients, respectively. These patients, most of whom were refractory to other AEDs, generally had positive experiences with zonisamide...
  32. ncbi request reprint Extended-release divalproex in child and adolescent outpatients with epilepsy
    Lydia Kernitsky
    Virginia Commonwealth University, Division of Child Neurology, Children s Pavilion, Richmond, Virginia 23298 0211, USA
    Epilepsia 46:440-3. 2005
    ..To determine whether valproic acid [divalproex (DVP)] extended-release, administered at a higher proportionate once-daily dosage, can be safely substituted for delayed-release or sprinkle in pediatric patients with epilepsy...
  33. ncbi request reprint Zonisamide in pediatric epilepsy: review of the Japanese experience
    Tracy A Glauser
    Department of Neurology, Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    J Child Neurol 17:87-96. 2002
    ..Additional controlled trials in children with partial- or generalized-onset seizures, infantile spasms, and Lennox-Gastaut syndrome are warranted to further delineate zonisamide's broad spectrum of efficacy and tolerability in children...
  34. ncbi request reprint Status epilepticus in a population-based Virginia twin sample
    Linda A Corey
    Virginia Institute for Psychiatric and Behavior Genetics, Department of Human Genetics, Virginia Commonwealth University, Richmond, Virginia 23298 0003, USA
    Epilepsia 45:159-65. 2004
    ....
  35. doi request reprint Phenomenology of prolonged febrile seizures: results of the FEBSTAT study
    S Shinnar
    Comprehensive Epilepsy Management Center, Montefiore Medical Center, Bronx, NY 10467, USA
    Neurology 71:170-6. 2008
    ..Febrile status epilepticus (FSE) has been associated with hippocampal injury and subsequent mesial temporal sclerosis and temporal lobe epilepsy. However, little is known about the semiology of FSE...
  36. ncbi request reprint Conclusion: having a plan to manage seizure emergencies
    John M Pellock
    Division of Child Neurology and Department of Neurology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA
    J Child Neurol 22:71S-73S. 2007
  37. ncbi request reprint Unmet needs in pediatric epilepsy
    Tracy A Glauser
    Department of Neurology, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    J Child Neurol 17:S1-3. 2002
    ..The articles are the result of a closed symposium held in January 2001...