Nisha Nagarkatti

Summary

Affiliation: Virginia Commonwealth University
Country: USA

Publications

  1. pmc Development of the calcium plateau following status epilepticus: role of calcium in epileptogenesis
    Nisha Nagarkatti
    Department of, Virginia Commonwealth University, Richmond, VA 23298, USA
    Expert Rev Neurother 9:813-24. 2009
  2. pmc Carisbamate prevents the development and expression of spontaneous recurrent epileptiform discharges and is neuroprotective in cultured hippocampal neurons
    Laxmikant S Deshpande
    Department of Neurology, Virginia Commonwealth University, Richmond, Virginia 23298, USA
    Epilepsia 49:1795-802. 2008
  3. pmc The novel antiepileptic drug carisbamate (RWJ 333369) is effective in inhibiting spontaneous recurrent seizure discharges and blocking sustained repetitive firing in cultured hippocampal neurons
    Laxmikant S Deshpande
    Department of Neurology, Virginia Commonwealth University, Richmond, VA 23298, USA
    Epilepsy Res 79:158-65. 2008
  4. pmc Dantrolene inhibits the calcium plateau and prevents the development of spontaneous recurrent epileptiform discharges following in vitro status epilepticus
    Nisha Nagarkatti
    Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, USA
    Eur J Neurosci 32:80-8. 2010
  5. pmc Levetiracetam inhibits both ryanodine and IP3 receptor activated calcium induced calcium release in hippocampal neurons in culture
    Nisha Nagarkatti
    Department of Neurology, Virginia Commonwealth University, Richmond, VA 23298, United States
    Neurosci Lett 436:289-93. 2008
  6. pmc Development of pharmacoresistance to benzodiazepines but not cannabinoids in the hippocampal neuronal culture model of status epilepticus
    Laxmikant S Deshpande
    Department of Neurology, Virginia Commonwealth University, Richmond, VA 23298, USA
    Exp Neurol 204:705-13. 2007

Collaborators

Detail Information

Publications6

  1. pmc Development of the calcium plateau following status epilepticus: role of calcium in epileptogenesis
    Nisha Nagarkatti
    Department of, Virginia Commonwealth University, Richmond, VA 23298, USA
    Expert Rev Neurother 9:813-24. 2009
    ..Thus, characterization of the post-injury Ca(2+) plateau may be important in eventually understanding the pathophysiology of epileptogenesis and preventing the progression to chronic epilepsy after brain injury...
  2. pmc Carisbamate prevents the development and expression of spontaneous recurrent epileptiform discharges and is neuroprotective in cultured hippocampal neurons
    Laxmikant S Deshpande
    Department of Neurology, Virginia Commonwealth University, Richmond, Virginia 23298, USA
    Epilepsia 49:1795-802. 2008
    ..Thus, development of drugs that would prevent or decrease the onset of epilepsy following brain injury represents an important area of research...
  3. pmc The novel antiepileptic drug carisbamate (RWJ 333369) is effective in inhibiting spontaneous recurrent seizure discharges and blocking sustained repetitive firing in cultured hippocampal neurons
    Laxmikant S Deshpande
    Department of Neurology, Virginia Commonwealth University, Richmond, VA 23298, USA
    Epilepsy Res 79:158-65. 2008
    ....
  4. pmc Dantrolene inhibits the calcium plateau and prevents the development of spontaneous recurrent epileptiform discharges following in vitro status epilepticus
    Nisha Nagarkatti
    Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, USA
    Eur J Neurosci 32:80-8. 2010
    ..These findings offer potential for a novel treatment to prevent the development of epileptiform discharges following brain injuries...
  5. pmc Levetiracetam inhibits both ryanodine and IP3 receptor activated calcium induced calcium release in hippocampal neurons in culture
    Nisha Nagarkatti
    Department of Neurology, Virginia Commonwealth University, Richmond, VA 23298, United States
    Neurosci Lett 436:289-93. 2008
    ..Thus, the ability of LEV to modulate the two major CICR systems demonstrates an important molecular effect of this agent on a major second messenger system in neurons...
  6. pmc Development of pharmacoresistance to benzodiazepines but not cannabinoids in the hippocampal neuronal culture model of status epilepticus
    Laxmikant S Deshpande
    Department of Neurology, Virginia Commonwealth University, Richmond, VA 23298, USA
    Exp Neurol 204:705-13. 2007
    ..Thus, the use of cannabinoids in the treatment of SE may offer a unique approach to controlling SE without the development of pharmacoresistance observed with conventional treatments...