Research Topics
| Elinore F McCance-KatzSummaryAffiliation: Virginia Commonwealth University Country: USA Publications
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Detail Information
Publications
Interactions between buprenorphine and antiretrovirals. II. The protease inhibitors nelfinavir, lopinavir/ritonavir, and ritonavirElinore F McCance-Katz
Virginia Commonwealth University, Richmond, USA
Clin Infect Dis 43:S235-46. 2006..Adjustments of doses of either buprenorphine or NFV, LPV/R, or RTV are not likely to be necessary when these drugs are administered for the treatment of opioid dependence and HIV disease...
Interaction between buprenorphine and atazanavir or atazanavir/ritonavirElinore F McCance-Katz
Virginia Commonwealth University, Richmond, VA, USA
Drug Alcohol Depend 91:269-78. 2007..Atazanavir or atazanavir/ritonavir may increase buprenorphine and buprenorphine metabolite concentrations and might require a decreased buprenorphine dose...- Treatment of opioid dependence and coinfection with HIV and hepatitis C virus in opioid-dependent patients: the importance of drug interactions between opioids and antiretroviral agentsElinore F McCance-Katz
Division of Addiction Psychiatry, Virginia Commonwealth University, Richmond, VA 23219, USA
Clin Infect Dis 41:S89-95. 2005..This promising finding may simplify the treatment of opioid-dependent patients with HIV disease and should also improve clinical outcomes for persons coinfected with HIV and hepatitis C virus... - Drug interactions between opioids and antiretroviral medications: interaction between methadone, LAAM, and delavirdineElinore F McCance-Katz
Virginia Commonwealth University, Richmond, Virginia 23298, USA
Am J Addict 15:23-34. 2006.... - Interactions between buprenorphine and antiretrovirals. I. The nonnucleoside reverse-transcriptase inhibitors efavirenz and delavirdineElinore F McCance-Katz
Virginia Commonwealth University, Richmond, USA
Clin Infect Dis 43:S224-34. 2006..Adjustments of doses of either buprenorphine or EFV or DLV are not likely to be necessary when these drugs are administered for the treatment of opiate dependence and HIV disease... - Gender effects following repeated administration of cocaine and alcohol in humansElinore F McCance-Katz
Medical College of Virginia at Virginia Commonwealth University, Division of Addiction Psychiatry, Richmond, Virginia 23219, USA
Subst Use Misuse 40:511-28. 2005..This double-blind, placebo-controlled, randomized study examined gender differences in response to administration of these drugs alone and in combination... - Office-based buprenorphine treatment for opioid-dependent patientsElinore F McCance-Katz
Division of Addiction Psychiatry, Department of Psychiatry, Virginia Commonwealth University, VA, USA
Harv Rev Psychiatry 12:321-38. 2004.... - Drug interactions between opioids and antiretroviral medications: interaction between methadone, LAAM, and nelfinavirElinore F McCance-Katz
Medical College of Virginia, Virginia Commonwealth University, PO Box 980109, Richmond, VA 23298, USA
Am J Addict 13:163-80. 2004..While no toxicities were observed, clinicians should be aware of the potential for drug interactions when patients require treatment with nelfinavir and these opiate medications... - The protease inhibitor lopinavir-ritonavir may produce opiate withdrawal in methadone-maintained patientsElinore F McCance-Katz
Medical College of Virginia, Virginia Commonwealth University, Richmond, VA 23298, USA
Clin Infect Dis 37:476-82. 2003..Lopinavir is a potent inducer of methadone metabolism, and treatment with L/R requires clinical monitoring and increased methadone doses in some patients, whereas ritonavir has no significant effect on methadone metabolism... - Interactions between buprenorphine and the protease inhibitors darunavir-ritonavir and fosamprenavir-ritonavirValerie A Gruber
Department of Psychiatry, University of California San Francisco, CA, USA
Clin Infect Dis 54:414-23. 2012..This study examined drug interactions between buprenorphine, a partial opioid agonist used for opioid dependence treatment and pain management, and the protease inhibitors (PIs) darunavir-ritonavir and fosamprenavir-ritonavir... - Acute cocaine responses following cocaethylene infusionJennifer Baker
Virginia Commonwealth University, Richmond, Virginia, USA
Am J Drug Alcohol Abuse 33:619-25. 2007..Agonist substitution therapy may have potential as an alternative treatment for cocaine dependence... 
Interactions between buprenorphine and antiretrovirals: nucleos(t)ide reverse transcriptase inhibitors (NRTI) didanosine, lamivudine, and tenofovirJennifer Baker
Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA
Am J Addict 19:17-29. 2010..Buprenorphine had no significant effect on NRTI concentrations. Concomitant use of buprenorphine with ddI, 3TC, or TDF results in neither a significant pharmacokinetic nor pharmacodynamic interaction...- Lack of clinically significant drug interactions between nevirapine and buprenorphineElinore F McCance-Katz
Department of Psychiatry, University of California, San Francisco, California, USA
Am J Addict 19:30-7. 2010..Buprenorphine did not alter nevirapine pharmacokinetics. Dose adjustments of either buprenorphine or nevirapine are not likely to be necessary when these drugs are coadministered for the treatment of opiate dependence and HIV disease... - Untreated HIV infection is associated with higher blood alcohol levelsElinore F McCance-Katz
Department of Psychiatry, Addiction Medicine Research, University of California San Francisco, San Francisco, CA, USA
J Acquir Immune Defic Syndr 60:282-8. 2012..This pilot study examines the relationship of untreated HIV infection to blood alcohol concentrations (BAC) relative to BAC after initiation of antiretroviral therapy (ART)... - Efficacy of dose and contingency management procedures in LAAM-maintained cocaine-dependent patientsAlison Oliveto
Department of Psychiatry, Yale School of Medicine and the VA CT Healthcare System, West Haven, CT, USA
Drug Alcohol Depend 79:157-65. 2005..These results suggest that an efficacious maintenance dose is necessary for contingencies to be effective in facilitating both opioid and cocaine abstinence... - Drug interactions of clinical importance among the opioids, methadone and buprenorphine, and other frequently prescribed medications: a reviewElinore F McCance-Katz
Department of Psychiatry, University of California, San Francisco, San Francisco, California, USA
Am J Addict 19:4-16. 2010..A substantial literature has accumulated on drug interactions between either methadone or buprenorphine with other medications when ingested concomitantly by humans. This review summarizes current literature in this area... - Disulfiram effects on responses to intravenous cocaine administrationJennifer R Baker
Virginia Commonwealth University, Division of Addiction Psychiatry, P O Box 980109, Richmond, VA 23219, USA
Drug Alcohol Depend 87:202-9. 2007..Disulfiram has been studied as a treatment for cocaine dependence. We report results of a randomized, double-blind, placebo-controlled, within-subject study to examine the interaction of disulfiram with intravenous cocaine... - Effect of buprenorphine and antiretroviral agents on the QT interval in opioid-dependent patientsJennifer R Baker
Addiction Psychiatry, Virginia Commonwealth University, Richmond, 23298, USA
Ann Pharmacother 40:392-6. 2006..QT interval increases were observed with buprenorphine/naloxone in combination with either delavirdine or ritonavir, which inhibit CYP3A4... - Effect of cocaine use on methadone pharmacokinetics in humansElinore F McCance-Katz
Department of Psychiatry, University of California San Francisco, San Francisco, California, USA
Am J Addict 19:47-52. 2010..09) and more rapid methadone clearance (p = .08). Regular cocaine use may adversely impact treatment outcomes for opioid dependence in those receiving methadone maintenance by decreasing methadone exposure... - Medical illness and comorbidities in drug users: implications for addiction pharmacotherapy treatmentJoy C Draper
Department of Obstetrics and Gynecology, Virginia Commonwealth University School of Medicine, Richmond, Virginia 23219, USA
Subst Use Misuse 40:1899-921, 2043-8. 2005..We conclude with a brief review of models of care that have been effective in addressing the needs of this challenging population that can provide additional means for enhancing the clinical care of substance users... - Effect of cocaine use on buprenorphine pharmacokinetics in humansElinore F McCance-Katz
Department of Psychiatry, University of California San Francisco, San Francisco, California, USA
Am J Addict 19:38-46. 2010..Regular cocaine users were younger (p = .0007), and used more heroin (p = .004) and cocaine (p < .0001). Regular cocaine use may result in lower buprenorphine plasma concentrations with potential for adverse clinical outcomes... - Modified directly observed therapy (MDOT) for injection drug users with HIV diseaseElinore F McCance-Katz
Departments of Psychiatry, Epidemiology and Social Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA
Am J Addict 11:271-8. 2002..The authors conclude that MDOT is a promising intervention for the treatment of IDUs with HIV disease, though significant drug interactions must be monitored for carefully and rapidly addressed... - Introduction to special issue "addiction pharmacotherapy and special populations"Elinore F McCance-Katz
Division of Addiction Psychiatry, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA
Subst Use Misuse 40:1895-7. 2005 - A brief overview of the clinical pharmacology of "club drugs"Gena Covell Britt
Division of Addiction Psychiatry, Virginia Commonwealth University, Richmond, Virginia 23219, USA
Subst Use Misuse 40:1189-201. 2005..The neurobiology, clinical pharmacology, and treatment issues for each are discussed... - Well-intentioned, but potentially spreading the virusElinore F McCance-Katz
Subst Use Misuse 38:2127-9. 2003 - Sex differences in cocaine-dependent individuals' response to disulfiram treatmentCharla Nich
Yale University School of Medicine, VA Connecticut Health Care System, West Haven, USA
Addict Behav 29:1123-8. 2004..Reasons for this apparent sex-based response are not clear, but possible mechanisms worthy of greater study include differences in alcohol use by sex as well as differences in dopamine-mediated responses to cocaine and disulfiram... - The pharmacokinetics of methadone following co-administration with a lamivudine/zidovudine combination tablet in opiate-dependent subjectsPetrie M Rainey
Yale University School of Medicine, New Haven, Conn, USA
Am J Addict 11:66-74. 2002..3 +/- 61.0 vs. 35.0 +/- 17.5 h) were detected. These results suggest that methadone dose change is not likely to be necessary for patients treated with lamivudine/zidovudine combination pharmacotherapy... - Buprenorphine assay and plasma concentration monitoring in HIV-infected substance usersRobin DiFrancesco
Pharmacotherapy Research Center, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, Buffalo, NY, USA
J Pharm Biomed Anal 44:188-95. 2007..Use of this combined BUP and ARV plasma concentration monitoring approach for a representative patient receiving BUP, atazanavir and efavirenz demonstrated its clinical application... - Novel metabolites of buprenorphine detected in human liver microsomes and human urineYan Chang
University of Utah, Center for Human Toxicology, Department of Pharmacology and Toxicology, 417 Wakara Way, Suite 2111, Salt Lake City, UT 84108, USA
Drug Metab Dispos 34:440-8. 2006..Examination of human urine from subjects taking buprenorphine showed the presence of M1 and M3; most of M1 was conjugated, whereas 60 to 70% of M3 was unconjugated... - The in vivo glucuronidation of buprenorphine and norbuprenorphine determined by liquid chromatography-electrospray ionization-tandem mass spectrometryWei Huang
Center for Human Toxicology, Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT 84108, USA
Ther Drug Monit 28:245-51. 2006..Because urinary elimination is limited ( approximately 11% of daily dose), the role of NBUPG in total clearance of buprenorphine is not yet known...