Research Topics
| S G KornsteinSummaryAffiliation: Virginia Commonwealth University Country: USA Publications
Research Grants
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Detail Information
Publications
The Prevention of Recurrent Episodes of Depression with Venlafaxine for Two Years (PREVENT) study: outcomes from the acute and continuation phasesMartin B Keller
Brown University, Providence, Rhode Island 02906, USA
Biol Psychiatry 62:1371-9. 2007..We evaluated the comparative efficacy and safety of venlafaxine extended release (ER) and fluoxetine in the acute and continuation phases of treatment...- Self-reported premenstrual exacerbation of depressive symptoms in patients seeking treatment for major depressionS G Kornstein
Department of Psychiatry, Virginia Commonwealth University, Richmond, VA 23298, USA
Psychol Med 35:683-92. 2005..The NIMH Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study provides a unique opportunity to evaluate PME in depressed women seeking treatment in primary care or psychiatric settings... - Low-dose sertraline in the treatment of moderate-to-severe premenstrual syndrome: efficacy of 3 dosing strategiesSusan G Kornstein
Virginia Commonwealth University School of Medicine, Richmond 23298 0710, USA
J Clin Psychiatry 67:1624-32. 2006.... - Gender differences in treatment response to sertraline versus imipramine in chronic depressionS G Kornstein
Department of Psychiatry, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA 23298 0710, USA
Am J Psychiatry 157:1445-52. 2000..The authors examined gender differences in treatment response to sertraline, a selective serotonin reuptake inhibitor (SSRI), and to imipramine, a tricyclic antidepressant, in chronic depression... - Clinical features of treatment-resistant depressionS G Kornstein
Department of Psychiatry, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298-0253, USA
J Clin Psychiatry 62:18-25. 2001..This article reviews the current literature regarding the clinical characteristics of treatment-resistant depression, with particular attention to the relevance of these factors for clinical decision making... - The evaluation and management of depression in women across the life spanS G Kornstein
Department of Psychiatry, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298-0710, USA
J Clin Psychiatry 62:11-7. 2001..This article will focus on special considerations in the evaluation and management of depression in women across the life span... - Expert guidelines for the treatment of severe PMS, PMDD, and comorbidities: the role of SSRIsMeir Steiner
Department of Psychiatry and Behavioral Neurosciences, McMaster University, Women s Health Concerns Clinic, St Joseph s Hospital, Hamilton, Ontario, Canada
J Womens Health (Larchmt) 15:57-69. 2006.... - Duloxetine in the treatment of major depressive disorder: comparisons of safety and tolerability in male and female patientsDonna E Stewart
University Health Network, University of Toronto, Ontario, Canada
J Affect Disord 94:183-9. 2006..CONCLUSIONS: No evidence of clinically meaningful sex differences in the safety and tolerability of duloxetine were uncovered... - Duloxetine efficacy for major depressive disorder in male vs. female patients: data from 7 randomized, double-blind, placebo-controlled trialsSusan G Kornstein
Department of Psychiatry, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, USA
J Clin Psychiatry 67:761-70. 2006..006) and women (p = .001) receiving duloxetine than placebo and showed no significant difference by gender. CONCLUSION: In this analysis of pooled data, the efficacy of duloxetine did not differ significantly in male and female patients... - Beyond remission: rationale and design of the Prevention of Recurrent Episodes of Depression with Venlafaxine for Two Years (PREVENT) StudySusan G Kornstein
Department of Psychiatry, Virginia Commonwealth University School of Medicine, Richmond, VA 23298 0710, USA
CNS Spectr 11:28-34. 2006.... - Escitalopram maintenance treatment for prevention of recurrent depression: a randomized, placebo-controlled trialSusan G Kornstein
Department of Psychiatry, Virginia Commonwealth University, Richmond, USA
J Clin Psychiatry 67:1767-75. 2006..The current trial examined the efficacy of maintenance escitalopram treatment in preventing depression recurrence in patients who responded to acute SSRI therapy... - Relative antidepressant efficacy of bupropion and the selective serotonin reuptake inhibitors in major depressive disorder: gender-age interactionsGeorge I Papakostas
Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Int Clin Psychopharmacol 22:226-9. 2007..This finding could, however, not be replicated when improvement in anxious/somatic symptoms was defined as a continuous measure... - Acute worsening of chronic depression during a double-blind, randomized clinical trial of antidepressant efficacy: differences by sex and menopausal statusAnne T Harvey
Via Christi Research, Inc, Wichita, Kan 67214, USA
J Clin Psychiatry 68:951-8. 2007.... 
Influences of hormone-based contraception on depressive symptoms in premenopausal women with major depressionElizabeth A Young
Department of Psychiatry and Molecular and Behavioral Neurosciences Institute, University of Michigan, MBNI, 205 Zina Pitcher Place, Ann Arbor, MI 48109 0720, and Massachusetts General Hospital, Boston 02114, USA
Psychoneuroendocrinology 32:843-53. 2007....- Prevention of recurrent episodes of depression with venlafaxine ER in a 1-year maintenance phase from the PREVENT StudyJames H Kocsis
Department of Psychiatry, Weill Cornell Medical College, New York, NY 10012, USA
J Clin Psychiatry 68:1014-23. 2007..To test the long-term efficacy and safety of venlafaxine extended-release (ER) in preventing recurrence in patients with major depression... - The Prevention of Recurrent Episodes of Depression with Venlafaxine for Two Years (PREVENT) Study: Outcomes from the 2-year and combined maintenance phasesMartin B Keller
Department of Psychiatry and Human Behavior, Brown University, Providence, RI 02906, USA
J Clin Psychiatry 68:1246-56. 2007..To report second-year results from the 2-year maintenance phase of a long-term study to evaluate the efficacy and safety of venlafaxine extended release (ER) in preventing recurrence of depression... - A comparison of initial duloxetine dosing strategies in patients with major depressive disorderVirgil G Whitmyer
Lilly Research Laboratories, Eli Lilly and Co, Indianapolis, Ind, USA
J Clin Psychiatry 68:1921-30. 2007..To compare the effects of starting doses of duloxetine taken with or without food on tolerability and efficacy in patients with major depressive disorder (MDD)... 
Maintenance therapy to prevent recurrence of depression: summary and implications of the PREVENT studySusan G Kornstein
Mood Disorders Institute, Institute for Women s Health, Department of Psychiatry, Virginia Commonwealth University, PO Box 980710, Richmond, VA 23298, USA
Expert Rev Neurother 8:737-42. 2008..The PREVENT study adds to current understanding regarding the benefits of long-term antidepressant therapy in preventing recurrence...- Relative antidepressant efficacy of venlafaxine and SSRIs: sex-age interactionsMichael E Thase
Department of Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213 2593, USA
J Womens Health (Larchmt) 14:609-16. 2005..To investigate whether differences in antidepressant efficacy are moderated by an interaction of age and gender... - Chronic depression: medication (nefazodone) or psychotherapy (CBASP) is effective when the other is notAlan F Schatzberg
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5717, USA
Arch Gen Psychiatry 62:513-20. 2005..Although various strategies are available to manage nonresponders to an initial treatment for depression, no controlled trials address the utility of switching from an antidepressant medication to psychotherapy or vice versa... - Symptomatic and syndromal anxiety in chronic forms of major depression: effect of nefazodone, cognitive behavioral analysis system of psychotherapy, and their combinationPhilip T Ninan
Department of Psychiatry, Emory University School of Medicine, Atlanta, GA 30329, USA
J Clin Psychiatry 63:434-41. 2002..Among patients with a concurrent anxiety disorder, nefazodone. either alone or in combination with CBASP, improves anxiety symptoms faster than CBASP alone, independent of depressive symptom reduction... - Differential effects of nefazodone and cognitive behavioral analysis system of psychotherapy on insomnia associated with chronic forms of major depressionMichael E Thase
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA 15213 2593, USA
J Clin Psychiatry 63:493-500. 2002..As nefazodone-mediated blockade of serotonin-2 receptors may directly relieve insomnia associated with depression, we examined the more specific effects of CBASP and nefazodone, singly and in combination, on sleep disturbances... - Sexual function and satisfaction in the treatment of chronic major depression with nefazodone, psychotherapy, and their combinationJohn Zajecka
Department of Psychiatry, Rush-Presbyterian-St. Luke's Medical Center, 1725 W. Harrison Street, Suite 955, Chicago, IL 60612, USA
J Clin Psychiatry 63:709-16. 2002..Treatment with nefazodone, CBASP, and combined treatment improved sexual interest/satisfaction, with greatest improvement observed with combined treatment... - Chronic depression and comorbid personality disorders: response to sertraline versus imipramineJames M Russell
Department of Psychiatry and Behavioral Sciences, The University of Texas Medical Branch at Galveston, 77555, USA
J Clin Psychiatry 64:554-61. 2003..Few studies, though, have systematically examined the clinical correlates of Axis II personality disorder comorbidity or its effect on treatment response or time to response... - Randomized, placebo-controlled trial of nefazodone maintenance treatment in preventing recurrence in chronic depressionAlan J Gelenberg
Department of Psychiatry, Health Sciences Center, University of Arizona, PO Box 245002, Tucson, AZ 85724-5002, USA
Biol Psychiatry 54:806-17. 2003..8%). Somnolence was significantly greater among the patients taking active medication (15.4%), compared with placebo (4.6%). CONCLUSIONS: Nefazodone is well-tolerated and is an effective maintenance therapy for chronic forms of MDD... - Gender differences in depression and response to antidepressant treatmentDiane M E Sloan
Clinical Services Department, CardinalHealth, Inc, 218 Colwyn Terrace, West Chester, PA 19380, USA
Psychiatr Clin North Am 26:581-94. 2003.... - A placebo-controlled trial of bupropion SR as an antidote for selective serotonin reuptake inhibitor-induced sexual dysfunctionAnita H Clayton
University of Virginia, Charlottesville, VA 22903, USA
J Clin Psychiatry 65:62-7. 2004..Exploratory analyses of the association of testosterone and sexual functioning in women in the study were also performed... - Self-reported depressive symptom measures: sensitivity to detecting change in a randomized, controlled trial of chronically depressed, nonpsychotic outpatientsA John Rush
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9086, USA
Neuropsychopharmacology 30:405-16. 2005..Global patient ratings such as the PGI-I, as opposed to specific item-based ratings, provide less valid findings... - Mental symptoms and disorders during pregnancyUriel Halbreich
Biobehavioral Research Program, State University of New York at Buffalo, Buffalo, New York, USA
CNS Spectr 9:176. 2004 - Chronic depression in womenSusan G Kornstein
Department of Psychiatry, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298-0710, USA
J Clin Psychiatry 63:602-9. 2002..Young women should be screened carefully and treated vigorously to prevent the serious consequences of this condition... - Continuation treatment of chronic depression: a comparison of nefazodone, cognitive behavioral analysis system of psychotherapy, and their combinationJames H Kocsis
Department of Psychiatry, Weill Cornell Medical College, New York, NY 10021, USA
Psychopharmacol Bull 37:73-87. 2003..COMB was associated with less symptom re-emergence during the continuation phase than either monotherapy, particularly for partial remitters... - Double-blind switch study of imipramine or sertraline treatment of antidepressant-resistant chronic depressionMichael E Thase
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
Arch Gen Psychiatry 59:233-9. 2002..Although various strategies have been proposed to treat antidepressant nonresponders, little controlled research has been published that examines prospectively the use of switching to an alternate antidepressant... - Development and validation of the Premenstrual Symptoms Impact Survey (PMSIS): a disease-specific quality of life assessment toolGene V Wallenstein
QualityMetric Incorporated, Lincoln, Rhode Island 02865, USA
J Womens Health (Larchmt) 17:439-50. 2008..To develop and validate the Premenstrual Symptoms Impact Survey (PMSIS), a brief web-based instrument for evaluating the impact of premenstrual symptoms on health-related quality of life (HRQOL)... - Does psychosocial functioning improve independent of depressive symptoms? A comparison of nefazodone, psychotherapy, and their combinationRobert M A Hirschfeld
Department of Psychiatry and Behavioral Sciences, University of Texas Medical Branch, Galveston, Texas 77555 0188, USA
Biol Psychiatry 51:123-33. 2002..This study compared efficacy of nefazodone, psychotherapy, and their combination in improving psychosocial functioning in chronically depressed outpatients...
Research Grants
- Symptom Onset Antidepressant Treatment for PMDDSusan Kornstein; Fiscal Year: 2009..The findings of this study, designed to reflect real-life implementation (i.e., symptom onset), will assist in developing practical treatment guidelines for women with PMDD. ..
- Symptom Onset Antidepressant Treatment for PMDDSusan Kornstein; Fiscal Year: 2007..The findings of this study, designed to reflect real-life implementation (i.e., symptom onset), will assist in developing practical treatment guidelines for women with PMDD. ..
- Symptom Onset Antidepressant Treatment for PMDDSusan G Kornstein; Fiscal Year: 2010..The findings of this study, designed to reflect real-life implementation (i.e., symptom onset), will assist in developing practical treatment guidelines for women with PMDD. ..