Research Topics
| Michael C KontosSummaryAffiliation: Virginia Commonwealth University Country: USA Publications
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Publications
An evaluation of the accuracy of emergency physician activation of the cardiac catheterization laboratory for patients with suspected ST-segment elevation myocardial infarctionMichael C Kontos
Department of Internal Medicine, Division of Cardiology, Virginia Commonwealth University Health System, Richmond, VA, USA
Ann Emerg Med 55:423-30. 2010..We assessed the accuracy of emergency physician cardiac catheterization laboratory activations, angiographic findings, outcomes, and treatment times among patients with and without STEMI...- Iodofiltic acid I 123 (BMIPP) fatty acid imaging improves initial diagnosis in emergency department patients with suspected acute coronary syndromes: a multicenter trialMichael C Kontos
Virginia Commonwealth University, Richmond, Virginia 23298 0051, USA
J Am Coll Cardiol 56:290-9. 2010.... - Mortality based on the presenting electrocardiogram in patients with myocardial infarction in the troponin eraMichael C Kontos
Department of Internal Medicine, Cardiology Division, Virginia Commonwealth University, Richmond, Virginia, USA
Am J Emerg Med 27:146-52. 2009..Because few patients with normal or nonspecific findings were included, outcomes in these patients are less clear, especially in the troponin era... - Value of simultaneous functional assessment in association with acute rest perfusion imaging for predicting short- and long-term outcomes in emergency department patients with chest painMichael C Kontos
Department of Internal Medicine, Cardiology Division, Virginia Commonwealth University, Richmond, VA 23298 0051, USA
J Nucl Cardiol 15:774-82. 2008..The role of functional data, commonly acquired with perfusion, has not been systematically evaluated... - Comparison of the modification of diet in renal disease and the Cockcroft-Gault equations for predicting mortality in patients admitted for exclusion of myocardial ischemiaMichael C Kontos
Department of Internal Medicine, Cardiology Division, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
Am J Cardiol 102:140-5. 2008..In conclusion, the C-G equation appears to be superior to the MDRD equation for predicting short- and long-term mortality in patients admitted for exclusion of ischemia, although differences are minor... - Troponin-positive, MB-negative patients with non-ST-elevation myocardial infarction: An undertreated but high-risk patient group: Results from the National Cardiovascular Data Registry Acute Coronary Treatment and Intervention Outcomes Network-Get With ThMichael C Kontos
Division of Cardiology, Department of Internal Medicine, Pauley Heart Center, Virginia Commonwealth University, Richmond, VA, USA
Am Heart J 160:819-25. 2010..How this affects treatment and outcomes has not been well described... - Outcomes in patients with chronicity of left bundle-branch block with possible acute myocardial infarctionMichael C Kontos
Division of Cardiology, Department of Internal Medicine, Virginia Commonwealth University, Richmond, USA
Am Heart J 161:698-704. 2011..Whether this pertains to lower risk emergency department patients with LBBB is unclear... - Predictive power of systolic function and congestive heart failure in patients with patients admitted for chest pain without ST elevation in the troponin eraMichael C Kontos
Cardiology Division, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, USA
Am Heart J 156:329-35. 2008..However, there are little data in which both of these variables were assessed in heterogenous patients admitted from the emergency department for exclusion of ischemia... - Treatment and outcomes in patients with myocardial infarction treated with acute β-blocker therapy: results from the American College of Cardiology's NCDR(®)Michael C Kontos
Department of Internal Medicine, Division of Cardiology, Pauley Heart Center, Virginia Commonwealth University, Richmond, USA
Am Heart J 161:864-70. 2011..Although β-blockers (BBs) reduce long-term mortality in patients after myocardial infarction (MI), data regarding acute usage are conflicting... 
Emergency department and office-based evaluation of patients with chest painMichael C Kontos
Department of Internal Medicine, Cardiology Division, Virginia Commonwealth University, Richmond, USA
Mayo Clin Proc 85:284-99. 2010....
Impact of the troponin standard on the prevalence of acute myocardial infarctionMichael C Kontos
Department of Internal Medicine, Cardiology Division, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA 23298 0051, USA
Am Heart J 146:446-52. 2003..The impact of this change has not been well described. Our objective was to determine the impact of a troponin standard on the prevalence of acute non-ST-elevation MI...- Coronary angiographic findings in patients with cocaine-associated chest painMichael C Kontos
Virginia Commonwealth University Health System Medical College of Virginia, Richmond, Virginia, USA
J Emerg Med 24:9-13. 2003..In conclusion, significant disease is found in the majority of patients with cocaine-associated MI or troponin elevations. In contrast, only a minority of those without myonecrosis have significant coronary disease... - Overestimation of aerobic capacity with the bruce treadmill protocol in patients being assessed for suspected myocardial ischemiaSherry Pinkstaff
Department of Physical Therapy, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, USA
J Cardiopulm Rehabil Prev 31:254-60. 2011..However, the potential to overestimate peak VO2 exists and may have clinical implications regarding the interpretation of exercise test data... - Left circumflex occlusion in acute myocardial infarction (from the National Cardiovascular Data Registry)W Kyle Stribling
Virginia Commonwealth University, Richmond, USA
Am J Cardiol 108:959-63. 2011.... - Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study)Antonio Abbate
Virginia Commonwealth University, VCU Pauley Heart Center, Richmond, Virginia, USA
Am J Cardiol 105:1371-1377.e1. 2010..If confirmed in larger trials, IL-1 blockade might represent a novel therapeutic strategy to prevent heart failure after AMI... - Implication of different cardiac troponin I levels for clinical outcomes and prognosis of acute chest pain patientsMichael C Kontos
Department of Internal Medicine, Cardiology Division, Medical College of Virginia, Virginia Commonwealth University, 12th and Marshall Streets, Richmond, VA 23298 0051, USA
J Am Coll Cardiol 43:958-65. 2004..We compared outcomes in patients with non-ST-segment elevation acute coronary syndromes (ACS) according to the degree of cardiac troponin I (cTnI) elevation... - A comprehensive strategy for the evaluation and triage of the chest pain patient: a cost comparison studyMichael C Kontos
Department of Radiology, Virginia Commonwealth University, Medical College of Virginia Hospital and Physicians of the Virginia Commonwealth, University Health Systems, Richmond, VA 23298 0051, USA
J Nucl Cardiol 10:284-90. 2003..We found previously that a chest pain evaluation system that uses MPI in low-risk patients was safe and effective, but the cost-effectiveness of this approach was not studied... - Utility of troponin I in patients with cocaine-associated chest painMichael C Kontos
Department of Internal Medicine, Cardiology Division, Virginia Commonwealth University, Medical College of Virginia Hospitals, Richmond, VA, USA
Acad Emerg Med 9:1007-13. 2002..Troponin sampling may offer greater diagnostic utility in these patients... - Ability of myoglobin to predict mortality in patients admitted for exclusion of myocardial infarctionMichael C Kontos
Cardiology Division, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA 23298 0051, USA
Am J Emerg Med 25:873-9. 2007..Because myoglobin elevations are often present in patients with renal insufficiency, it is possible that the predictive value of myoglobin is secondary to identifying patients with renal insufficiency... - Sensitivity of acute rest myocardial perfusion imaging for identifying patients with myocardial infarction based on a troponin definitionMichael C Kontos
Department of Internal Medicine, Cardiology Division, Medical College of Virginia, Virginia Commonwealth University, Richmond, USA
J Nucl Cardiol 11:12-9. 2004..A recent recommendation is that patients with increased troponin levels be diagnosed as having MI. The sensitivity and characteristics of patients who have elevated troponin levels who also underwent early MPI are unknown... - Risk of heart failure complication during hospitalization for acute myocardial infarction in a contemporary population: insights from the National Cardiovascular Data ACTION RegistryRavi V Shah
Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Circ Heart Fail 5:693-702. 2012..Patients with acute myocardial infarction (MI) complicated by heart failure (HF) are subject to higher mortality during the index hospitalization. Early risk prediction and intervention may help prevent HF-related morbidity and mortality... - Outcomes in patients admitted for chest pain with renal failure and troponin I elevationsMichael C Kontos
Cardiology Division, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, USA
Am Heart J 150:674-80. 2005..The significance of troponin I (TnI) elevations in patients with renal failure (RF) admitted for possible myocardial ischemia is unclear. We therefore compared outcomes in patients with and without TnI elevations based on renal function... - Predictive power of ejection fraction and renal failure in patients admitted for chest pain without ST elevation in the troponin eraMichael C Kontos
Cardiology Division, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, USA
Am Heart J 150:666-73. 2005..There are limited data assessing the predictive value of EF and RF compared with clinical variables in patients without ST elevation using troponin as the diagnostic MI criteria... - Incidence of high-risk acute coronary syndromes and eligibility for glycoprotein IIb/IIIa inhibitors among patients admitted for possible myocardial ischemiaMichael C Kontos
Medical College of Virginia Hospitals of Virginia Commonwealth University, Richmond, VA, USA
Am Heart J 143:70-5. 2002..However, little is known about how many patients are actually eligible for treatment. Our purpose was to determine how many patients admitted for possible myocardial infarction (MI) meet GP IIb/IIIa inhibitor treatment criteria... - Implication of the new low-density lipoprotein goals in dyslipidemia management of patients with acute coronary syndromeMichael C Kontos
Department of Internal Medicine, Cardiology Division, Virginia Commonwealth University, Richmond, VA 23298 0051, USA
Mayo Clin Proc 82:551-5. 2007..To assess the ability of patients with an acute coronary syndrome (ACS) to meet the recommended low-density lipoprotein cholesterol (LDL-C) goal of 100 mg/dL and optional aggressive lowering to 70 mg/dL... - Usefulness of decrease in oxygen uptake efficiency slope to identify myocardial perfusion defects in men undergoing myocardial ischemic evaluationSherry Pinkstaff
Department of Physical Therapy, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, Virginia
Am J Cardiol 106:1534-9. 2010.... - Myocardial salvage in patients with non-ST-elevation myocardial infarction determined by myocardial perfusion imagingMichael C Kontos
Department of Department of Internal Medicine, Cardiology Division, Virginia Commonwealth University, Richmond, Virginia, USA
Am J Cardiol 95:398-401. 2005.... - Diagnostic strategies for the evaluation of the patient presenting with chest painRobert L Jesse
Cardioogy Division, Virginia Commonwealth University Medical Center, Richmond, USA
Prog Cardiovasc Dis 46:417-37. 2004 - The impact of prehospital activation of the cardiac catheterization team on time to treatment for patients presenting with ST-segment-elevation myocardial infarctionTeresa Camp-Rogers
Department of Emergency Medicine, Virginia Commonwealth University Medical Center, Richmond, VA 23298, USA
Am J Emerg Med 29:1117-24. 2011.... - Noninvasive prediction of left ventricular systolic dysfunction in patients with clinically suspected heart failure using acoustic cardiographyDouglas L Kosmicki
Division of Cardiology, University of Utah, Salt Lake City, UT 84132 2401, USA
Congest Heart Fail 16:249-53. 2010..89 vs 0.64; P<.0001). Noninvasive computerized acoustic cardiography predicted LVSD in a diverse population. This acoustic cardiographic model outperformed BNP alone for predicting LVSD... - Emergency physician-initiated cath lab activation reduces door to balloon times in ST-segment elevation myocardial infarction patientsMichael C Kontos
Department of Internal Medicine, Division of Cardiology, Virginia Commonwealth University, Richmond, VA 23298 0051, USA
Am J Emerg Med 29:868-74. 2011..We evaluated the impact of emergency physician (EP)-initiated primary percutaneous coronary intervention (PCI) via a single-group page on door to balloon (D2B) interval times in patients with ST-segment elevation myocardial infarction... - Imaging in the evaluation of the patient with suspected acute coronary syndromeMichael C Kontos
Virginia Commonwealth University, VCU Medical Center, Richmond, VA 23298 0051, USA
Cardiol Clin 23:517-30, vii. 2005..This necessity further increases the need for rapid triage tools, especially in the current setting of ED and hospital overcrowding that has become the norm in large urban centers... - Comparison of 2-dimensional echocardiography and myocardial perfusion imaging for diagnosing myocardial infarction in emergency department patientsMichael C Kontos
Department of Internal Medicine (Cardiology, Medical College of Virginia, Campus of Virginia Commonwealth University, Richmond, VA, USA
Am Heart J 143:659-67. 2002..82; P <.001). CONCLUSION: Both echocardiography and MPI have a high sensitivity for identifying patients in the emergency department who have MI. False negative studies with either technique were associated with small MIs... - Impact of congestive heart failure treatment on peripheral microvascular tissue oxygenationChristopher J Hogan
Virginia Commonwealth University Reanimation Engineering Science Center, Virginia Commonwealth University Medical Center, Richmond, USA
Congest Heart Fail 17:294-302. 2011..Lack of improvement may be associated with higher rates of death and readmission... - The influence of referral source on characteristics of patients undergoing cardiac stress testing: emergency department versus outpatient officeSherry Pinkstaff
Department of Phyical Therapy, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 23298 0224, USA
Postgrad Med 123:36-41. 2011..Whether patients referred for cardiac stress testing from these referral sources differ in clinically significant ways is unknown, and is thus the purpose of this investigation... - Clinical outcomes in patients with acute left circumflex/obtuse marginal occlusion presenting with myocardial infarctionW Kyle Stribling
Virginia Commonwealth University Health System, Richmond, Virginia 23298, USA
J Interv Cardiol 24:27-33. 2011..This study aims to define the incidence of NSTEMI in pts presenting with LCx/OM occlusion and analyzes clinical characteristics and outcomes in those presenting with NSTEMI compared to STEMI... - Comparison of contrast echocardiography with single-photon emission computed tomographic myocardial perfusion imaging in the evaluation of patients with possible acute coronary syndromes in the emergency departmentMichael C Kontos
Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23298, USA
Am J Cardiol 91:1099-102. 2003 - Imaging in the evaluation of the patient with suspected acute coronary syndromeMichael C Kontos
Virginia Commonwealth University, VCU Medical Center, Medical College of Virginia Hospitals, Richmond, VA, USA
Semin Nucl Med 33:246-58. 2003..The challenge now lays in developing a strategy that uses these and future techniques most appropriately to support optimal medical decision making... - Patients with coronary artery disease who present with chest pain have significantly elevated platelet contractile force and clot elastic modulusAshok Krishnaswami
Department of Internal Medicine, Medical College of Virginia Hospitals of Virginia Commonwealth University, Richmond, Virginia, USA
Thromb Haemost 88:739-44. 2002..008 for patients with CAD). Patients with electrocardiographic evidence of ischemia had the highest PCF and CEM values of any patient group. Increased PCF and CEM were not due to higher platelet counts, and PCF did not differ by race... - Myocardial perfusion imaging in the acute care settingMichael C Kontos
Department of Internal Medicine, Cardiology Division, Virginia Commonwealth University, Richmond, VA, USA
J Nucl Cardiol 14:S125-32. 2007 - Acute rest myocardial perfusion imaging for chest painMichael C Kontos
Department of Internal Medicine, Medical College of Virginia, Richmond, USA
J Nucl Cardiol 11:470-81. 2004 - Body surface mapping vs 12-lead electrocardiography to detect ST-elevation myocardial infarctionJoseph P Ornato
Internal Medicine Virginia Commonwealth University Health System, PO Box 980401, Richmond, VA 23298 0401, USA
Am J Emerg Med 27:779-84. 2009..We conclude that BSM using 80-lead BSM ECG is more sensitive for detection of STEMI than 12-lead ECG, while retaining similar specificity... - Anti-cardiolipin and increased serum adhesion molecule levels in patients with aggressive periodontitisHarvey A Schenkein
Clinical Research Center for Periodontal Disease, Virginia Commonwealth University School of Dentistry, Richmond, VA 23298, USA
J Periodontol 78:459-66. 2007..Anti-CL is known to promote vascular inflammation and thrombosis... - Acoustic cardiography S3 detection use in problematic subgroups and B-type natriuretic peptide "gray zone": secondary results from the Heart failure and Audicor technology for Rapid Diagnosis and Initial Treatment Multinational InvestigationAlan S Maisel
Division of Cardiology, Veterans Affairs San Diego Health Care System, San Diego, CA 92161, USA
Am J Emerg Med 29:924-31. 2011..Our goal in this secondary analysis was to determine if the strength of the S3 can provide diagnostic/prognostic information in problematic heart failure subgroups... - Quantifying exertion level during exercise stress testing using percentage of age-predicted maximal heart rate, rate pressure product, and perceived exertionSherry Pinkstaff
Department of Physical Therapy, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 23140, USA
Mayo Clin Proc 85:1095-100. 2010.... - Right ventricular cardiomyocyte apoptosis in patients with acute myocardial infarction of the left ventricular wallAntonio Abbate
Virginia Commonwealth University, Pauley Heart Center, Richmond, Virginia, USA
Am J Cardiol 102:658-62. 2008..91, p = 0.002 for RV free wall thickness). In conclusion, patients with cardiac remodeling after AMI had a significant increase in RV apoptosis even when ischemic involvement of the RV wall was not apparent... - Evaluating heart failure after implantation of mechanical circulatory support devicesKeyur B Shah
The Advanced Heart Failure and Transplantation Program, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 23298, USA
Curr Heart Fail Rep 9:65-74. 2012.... - Peripheral tissue oxygenation improves during ED treatment of acute heart failureChristopher J Hogan
Department of Emergency Medicine, Virginia Commonwealth University Medical Center, Medical College of Virginia Campus, Richmond, VA 23238 0401, USA
Am J Emerg Med 30:196-202. 2012..The objective of the study was to quantitatively characterize peripheral tissue microvascular oxygenation during emergency department (ED) treatment of acute heart failure (HF)... - Diagnosis and characterization of left ventricular hypertrophy by computerized acoustic cardiography, brain natriuretic peptide, and electrocardiographyR Kevin Rogers
University of Utah, Division of Cardiology, Salt Lake City, UT 84132 2401, USA
J Electrocardiol 41:518-25. 2008.... - American Society of Nuclear Cardiology position statement on radionuclide imaging in patients with suspected acute ischemic syndromes in the emergency department or chest pain centerFrans J Th Wackers
J Nucl Cardiol 9:246-50. 2002 - The impact of electrocardiographic left ventricular hypertrophy and bundle branch block on the triage and outcome of ED patients with a suspected acute coronary syndrome: a multicenter studyJ Hector Pope
Center for Cardiobascular Health Services Research, Division of Clinical Care Research, Department of Medicine, Tufts New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
Am J Emerg Med 22:156-63. 2004..With a short-term mortality rate 3.5 times that for patients without ECG-LVH, selected patients with ECG-LVH and symptoms suggesting ACS might benefit from hospitalization for further evaluation... - Meta-analysis of ischemia-modified albumin to rule out acute coronary syndromes in the emergency departmentFrank Peacock
Department of Emergency Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Am Heart J 152:253-62. 2006..4% and 97.1% and, for longer-term outcomes, were 89.2% and 94.5%, respectively. CONCLUSIONS: A negative TPT of a nondiagnostic electrocardiogram, negative troponin, and negative IMA has a high NPV for excluding ACS in the ED... - Management of ST-segment elevation myocardial infarction in EDsDeborah B Diercks
University of California, Davis Medical Center, Sacramento, CA, USA
Am J Emerg Med 26:91-100. 2008..In addition, multiple new antithrombin agents are being investigated. The choice adjunctive treatments should be based on specific patient populations and on the initial reperfusion strategy... - Treatment and outcomes of patients with evolving myocardial infarction: experiences from the SYNERGY trialChadwick D Miller
Department of Emergency Medicine, Wake Forest University School of Medicine, Winston Salem, NC, USA
Eur Heart J 28:1079-84. 2007..We compared the initial treatment and clinical outcomes of patients presenting with evolving MI (EMI) with those presenting with MI... - Left ventricular diastolic filling pattern at Doppler echocardiography and apoptotic rate in fatal acute myocardial infarctionGianfranco Sinagra
Institutes of Cardiology, Anatomic Pathology, and Internal Medicine, University of Trieste, Trieste, Italy
Am J Cardiol 99:307-9. 2007..030). In conclusion, patients with severe postinfarction LV diastolic dysfunction had significantly higher rates of cardiomyocyte loss by apoptosis, which may partly explain their unfavorable outcome... - Incremental value of cardiac imaging in patients presenting to the emergency department with chest pain and without ST-segment elevation: a multicenter studySanjiv Kaul
Cardiovascular Imaging Center, Cardiovascular Division, University of Virginia, Charlottesville, VA 22908 0158, USA
Am Heart J 148:129-36. 2004....