Affiliation: Virginia Commonwealth University
- Proteomic analysis of the tumorigenic human prostate cell line M12 after microcell-mediated transfer of chromosome 19 demonstrates reduction of vimentinXuhui Liu
Department of Pathology, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, VA 23298, USA
Electrophoresis 24:3445-53. 2003..These studies demonstrate that application of proteomic analysis to specific problems in an experimental context can yield biologically relevant information about the prostate cancer cell phenotype...
- A novel tumorigenic human prostate epithelial cell line (M2205): molecular cytogenetic characterization demonstrates C-MYC amplification and jumping translocationsColleen Jackson-Cook
Department of Human Genetics, Medical College of Virginia Campus of Virginia Commonwealth University, Richmond, VA 23298 0033, USA
Cancer Genet Cytogenet 141:56-64. 2003....
- Epistatic and environmental control of genome-wide gene expressionTimothy P York
Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia 23298 0003, USA
Twin Res Hum Genet 8:5-15. 2005....
- Increased frequency of micronuclei in adults with a history of childhood sexual abuse: a discordant monozygotic twin studyTimothy P York
Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America
PLoS ONE 8:e55337. 2013....
- Mechanisms leading to the formation of micronuclei containing sex chromosomes differ with ageKimberly H Jones
Department of Pathology, Virginia Commonwealth University, Richmond, VA, USA
Mutat Res 747:207-17. 2012..Therefore, when analyzing MN frequencies, one may also wish to evaluate the imbalances present in both the binucleates and MN to facilitate the recognition of varying cellular responses to environmental or genotoxic exposures...
- Constitutional and acquired autosomal aneuploidyColleen Jackson-Cook
Department of Pathology, Virginia Commonwealth University, Richmond, VA 23298, USA
Clin Lab Med 31:481-511, vii. 2011....
- The phenotype of persons having mosaicism for trisomy 21/Down syndrome reflects the percentage of trisomic cells present in different tissuesPaulie Papavassiliou
Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Virginia 23298 0662, USA
Am J Med Genet A 149:573-83. 2009..The results of this study should enable geneticists and other health care professionals to provide information regarding optimal diagnostic approaches and anticipated clinical outcomes...
- A mutation inactivating the mitochondrial inner membrane folate transporter creates a glycine requirement for survival of chinese hamster cellsErin A McCarthy
Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia 23298, USA
J Biol Chem 279:33829-36. 2004..We conclude that we have defined the cause of the glyB auxotrophy and that the glyB mft mutation identified a region of this mitochondrial folate carrier vital to its transport function...
- Molecular techniques for identifying HCC origin and biology after orthotopic liver transplantationValeria R Mas
Division of Transplant Surgery, Department of Surgery, Medical College of Virginia of Virginia Commonwealth University, Richmond, Virginia, PO Box 980254, Richmond, VA 23298, USA
Diagn Mol Pathol 15:90-4. 2006..These techniques provided consistent evidence that the second HCC was a recurrence of the primary tumor...
- Micronuclei with multiple copies of the X chromosome: do chromosomes replicate in micronuclei?Natalia Tszine Leach
Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Mutat Res 554:89-94. 2004..A possible mechanism for this observation is that the chromosome(s) or chromatid(s) contained within the micronuclei successfully completed one or more cycles of replication after their expulsion from the primary nucleus...
- High BAALC expression associates with other molecular prognostic markers, poor outcome, and a distinct gene-expression signature in cytogenetically normal patients younger than 60 years with acute myeloid leukemia: a Cancer and Leukemia Group B (CALGB) stChristian Langer
Division of Hematology and Oncology, Department of Internal Medicine, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA
Blood 111:5371-9. 2008..We conclude that high BAALC expression is an independent adverse prognostic factor and is associated with a specific gene-expression profile...