Research Topics
| Michael EdmondSummaryAffiliation: Virginia Commonwealth University Country: USA Publications
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Publications
Systemic inflammatory response syndrome in adult patients with nosocomial bloodstream infections due to enterococciKatharine Bar
Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, USA
BMC Infect Dis 6:145. 2006..This study analyzed the inflammatory response of Enterococcal BSI, contrasting infections from vancomycin-resistant and vancomycin-susceptible isolates...
Mandatory public reporting in the USA: an example to follow?Michael B Edmond
Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA 23298 0019, USA
J Hosp Infect 65:182-8. 2007..The transformation of healthcare in the USA into a commodity has fostered a strong role for consumer advocacy to which state legislative bodies have shown willingness to respond...
Active surveillance cultures are not required to control MRSA infections in the critical care settingMichael B Edmond
Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA
Am J Infect Control 36:461-3. 2008..We observed reductions in all infections, including those caused by MRSA, and conclude that control of MRSA in the critical care setting does not require active surveillance cultures...
Who is steering the ship? External influences on infection control programsMichael Edmond
Virginia Commonwealth University School of Medicine, Richmond 23298 0019, USA
Clin Infect Dis 46:1746-50. 2008....
Hospital and community fluoroquinolone use and resistance in Staphylococcus aureus and Escherichia coli in 17 US hospitalsConan MacDougall
Department of Pharmacy, School of Pharmacy, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 23298, USA
Clin Infect Dis 41:435-40. 2005..coli in hospitals. Antimicrobial use in hospitals and communities may have different relative importance with regard to resistance in different pathogens encountered in hospitals...
Community-acquired methicillin-resistant Staphylococcus aureus (MRSA): new issues for infection controlRichard P Wenzel
Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, and Medical College of Virginia Hospitals, 1101 East Broad Street, P O Box 980663, Richmond, VA 23298, USA
Int J Antimicrob Agents 30:210-2. 2007..Questions about changing prophylactic and empirical therapy as well as the use of intravenous immunoglobulin for life-threatening infections are addressed...
Pseudomonas aeruginosa, Staphylococcus aureus, and fluoroquinolone useConan MacDougall
Virginia Commonwealth University School of Pharmacy, Richmond, Virginia 23298-0533, USA
Emerg Infect Dis 11:1197-204. 2005..The ecologic relationship between fluoroquinolone use and resistance is complex and requires further study...
A controlled trial of universal gloving versus contact precautions for preventing the transmission of multidrug-resistant organismsGonzalo M L Bearman
Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, VA, USA
Am J Infect Control 35:650-5. 2007..Contact precautions are recommended to reduce the transmission of multidrug-resistant organisms. However, the optimal method for control of multidrug-resistant organisms remains unclear...
Screening for MRSA: a flawed hospital infection control interventionRichard P Wenzel
Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia, USA
Infect Control Hosp Epidemiol 29:1012-8. 2008....
Trial of universal gloving with emollient-impregnated gloves to promote skin health and prevent the transmission of multidrug-resistant organisms in a surgical intensive care unitGonzalo Bearman
Division of Infectious Diseases, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, Virginia 23298 0019, USA
Infect Control Hosp Epidemiol 31:491-7. 2010....
A statewide survey of nosocomial infection surveillance in acute care hospitalsMichael B Edmond
Department of Infection Control and Epidemiology, Virginia Commonwealth University Medical Center, Richmond, VA 23298 0019, USA
Am J Infect Control 33:480-2. 2005..7. Statewide, an additional 160 ICPs at an estimated annual cost of 11.5 million dollars would be required if reporting of all nosocomial infections were mandated...
Lessons from severe acute respiratory syndrome (SARS): implications for infection controlRichard P Wenzel
Department of Internal Medicine, Virginia Commonwealth University Medical Center, Richmond, VA
Arch Med Res 36:610-6. 2005..Herein we relate our perspectives on useful lessons derived from a review of the SARS epidemic...
Practices and an assessment of health care workers' perceptions of compliance with infection control knowledge of nosocomial infectionsMezgebe Berhe
Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA 23298, USA
Am J Infect Control 33:55-7. 2005
Predicting hospital rates of fluoroquinolone-resistant Pseudomonas aeruginosa from fluoroquinolone use in US hospitals and their surrounding communitiesRonald E Polk
School of Pharmacy, Department of Pharmacy, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 23298, USA
Clin Infect Dis 39:497-503. 2004..aeruginosa. Levofloxacin was associated with resistance, but ciprofloxacin was not. Most of the variability in resistance rates is explained by volume of fluoroquinolone use, both in the hospital and the surrounding community...
Vancomycin susceptibility of oxacillin-resistant Staphylococcus aureus isolates causing nosocomial bloodstream infectionsSandra M Tallent
Department of Internal Medicine, Medical College of Virginia Campus of Virginia Commonwealth University, Richmond, Virginia 23298, USA
J Clin Microbiol 40:2249-50. 2002..Only one isolate exhibiting heterotypic resistance was detected. Thus, vancomycin heteroresistance in clinical bloodstream isolates remains rare in the United States...
Community-acquired methicillin resistant Staphylococcus aureus in a women's collegiate basketball teamMichael P Stevens
Department of Internal Medicine, Virginia Commonwealth University Medical Center, Richmond, VA 23298 0509, USA
South Med J 101:1067-8. 2008..Interestingly, multiple MRSA strains were discovered on testing of the team, raising concern that the prevalence of colonization in this population may be high...
Impact of 2 different levels of performance feedback on compliance with infection control process measures in 2 intensive care unitsSusan Assanasen
Divisions of Infectious Diseases and Quality Health Care, Department of Internal Medicine, Virginia Commonwealth University Medical Center, Richmond, VA, USA
Am J Infect Control 36:407-13. 2008..Performance monitoring and feedback of infection control process measures is an important tool for improving guideline adherence. Different feedback strategies may lead to distinctive outcomes...
Managing SARS amidst uncertaintyRichard P Wenzel
Department of Internal Medicine, Virginia Commonwealth University, Richmond, USA
N Engl J Med 348:1947-8. 2003
Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance studyHilmar Wisplinghoff
Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, USA
Clin Infect Dis 39:309-17. 2004..CONCLUSION: In this study, one of the largest multicenter studies performed to date, we found that the proportion of nosocomial BSIs due to antibiotic-resistant organisms is increasing in US hospitals...
Susceptibility of coagulase-negative staphylococcal nosocomial bloodstream isolates to the chlorhexidine/silver sulfadiazine-impregnated central venous catheterAdriana E Rosato
Department of Internal Medicine, School of Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA
Am J Infect Control 32:486-8. 2004
Central venous catheter colonization by linezolid-resistant, vancomycin-susceptible Enterococcus faecalisAlexandre R Marra
Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia, USA
J Clin Microbiol 44:1915-6. 2006..A strain resistant to this antimicrobial but susceptible to vancomycin was found to cause central venous catheter colonization in a patient who never received linezolid...
Measurement and feedback of infection control process measures in the intensive care unit: Impact on complianceMezgebe Berhe
Division of Infectious Diseases, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA
Am J Infect Control 34:537-9. 2006..9) in the STICU, respectively. CONCLUSION: Feedback of process measures lowered the use of femoral catheters and improved the proportion of elevated head of beds in 2 ICUs, but there was no significant improvement in hand hygiene...
Surgical site infection surveillance for neurosurgical procedures: a comparison of passive surveillance by surgeons to active surveillance by infection control professionalsDiane Heipel
Virginia Commonwealth University Medical Center, Richmond, Virginia 23298 0019, USA
Am J Infect Control 35:200-2. 2007..Although concurrent surveillance of SSIs by ICPs at our medical center documented an incidence of 2.2 SSIs per 100 procedures, the neurosurgeons perceived a much higher rate of SSIs...
Time to blood culture positivity as a predictor of clinical outcome of Staphylococcus aureus bloodstream infectionAlexandre R Marra
A D Williams Clinic, 1201 East Marshall Street, 6th Floor, Room 6 602, P O Box 980019, Richmond, VA 23298, USA
J Clin Microbiol 44:1342-6. 2006..aureus (OR, 9.3; 95% CI, 1.45 to 59.23), and TTPs of </=12 h (OR, 6.9; 95% CI, 1.07 to 44.66). In this historical cohort study of BSIs due to S. aureus, a TTP of </=12 h was a predictor of the clinical outcome...
Health care-associated transmission of hepatitis B and C in oncology careMichael P Stevens
Division of Infectious Diseases, Virginia Commonwealth University Medical Center, 1201 East Marshall Street, P O Box 980019, Richmond, Virginia 23298 0019, USA
Clin Liver Dis 14:69-74; viii. 2010..Optimizing infection control in inpatient and outpatient oncology settings is essential in preventing the health care-associated transmission of hepatitis B and C to oncology patients...
Endocarditis due to vancomycin-resistant enterococci: case report and review of the literatureMichael P Stevens
Virginia Commonwealth University Medical Center, Richmond, VA 23298-0019, USA
Clin Infect Dis 41:1134-42. 2005..One-third of patients require surgical treatment. Optimal antimicrobial therapy remains undefined, but an attempt to identify bactericidal combination therapy should be sought...
Look before you leap: active surveillance for multidrug-resistant organismsDaniel J Diekema
University of Iowa Healthcare, Iowa City, IA, USA
Clin Infect Dis 44:1101-7. 2007....
Current trends in the epidemiology of nosocomial bloodstream infections in patients with hematological malignancies and solid neoplasms in hospitals in the United StatesHilmar Wisplinghoff
Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, 50935 Cologne, Germany
Clin Infect Dis 36:1103-10. 2003..The source of BSI was not determined for 57% of patients. The crude mortality rate was 36% for neutropenic patients and 31% for nonneutropenic patients...
Systemic inflammatory response syndrome in adult patients with nosocomial bloodstream infection due to Pseudomonas aeruginosaAlexandre R Marra
Division of Infectious Diseases, Brazil UNIFESP EPM Hospital São Paulo HSP, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
J Infect 53:30-5. 2006..To evaluate relationships between the inflammatory response, clinical course, and outcome of nosocomial BSI due to Pseudomonas aeruginosa...
Comparison of the systemic inflammatory response syndrome between monomicrobial and polymicrobial Pseudomonas aeruginosa nosocomial bloodstream infectionsAlexandre R Marra
Department of Infectious Diseases, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
BMC Infect Dis 5:94. 2005..The purpose of this study was to compare differences in systemic inflammatory response and mortality between monomicrobial and polymicrobial nBSI with Pseudomonas aeruginosa...
Systemic inflammatory response syndrome in nosocomial bloodstream infections with Pseudomonas aeruginosa and Enterococcus Species: comparison of elderly and nonelderly patientsAlexandre R Marra
Division of Infectious Diseases, Universidade Federal de São Paulo Hospital São Paulo, Sao Paulo, Brazil
J Am Geriatr Soc 54:804-8. 2006..is different in elderly patients than in younger patients...
Controlled trial measuring the effect of a feedback intervention on hand hygiene compliance in a step-down unitAlexandre R Marra
Intensive Care Unit, Hospital Israelita Albert Einstein, Sao Paulo, Brazil
Infect Control Hosp Epidemiol 29:730-5. 2008..To evaluate hand hygiene compliance in 2 adult step-down units (SDUs)...
Nosocomial bloodstream infections in pediatric patients in United States hospitals: epidemiology, clinical features and susceptibilitiesHilmar Wisplinghoff
Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Germany
Pediatr Infect Dis J 22:686-91. 2003..CONCLUSION: Nosocomial BSI occurred predominantly in very young and/or critically ill children. Gram-positive pathogens predominated across all ages, and increasing antimicrobial resistance was observed in pediatric patients...
Listening to SARS: lessons for infection controlRichard P Wenzel
Ann Intern Med 139:592-3. 2003
Bloodstream infections with metallo-beta-lactamase-producing Pseudomonas aeruginosa: epidemiology, microbiology, and clinical outcomesAlexandre R Marra
Divsion of Infectious Diseases, Universidade Federal de Sao Paulo, Brasil UNIFESP EPM Hospital São Paulo, Escola Paulista de Medicina, Rua Napoleao de Barros, 715 7th andar, CEP 04023 062, Sao Paulo, SP, Brazil
Antimicrob Agents Chemother 50:388-90. 2006..We evaluated the epidemiological and microbiological characteristics of monomicrobial bloodstream infections caused by MBL-producing P. aeruginosa isolates, as well as the clinical outcomes in patients with these infections...
Nosocomial bloodstream infections caused by Klebsiella pneumoniae: impact of extended-spectrum beta-lactamase (ESBL) production on clinical outcome in a hospital with high ESBL prevalenceAlexandre R Marra
Division of Infectious Diseases, Universidade Federal de Sao Paulo, Brasil UNIFESP EPM Hospital São Paulo HSP, Brasil
BMC Infect Dis 6:24. 2006....
Comparison of severity of illness scoring systems for patients with nosocomial bloodstream infection due to Pseudomonas aeruginosaAlexandre R Marra
Division of Infectious Diseases, Universidade Federal de Sao Paulo, Brasil UNIFESP EPM Hospital São Paulo HSP, Brazil
BMC Infect Dis 6:132. 2006..We compared three severity of illness scoring systems for predicting mortality in patients with nBSI due to Pseudomonas aeruginosa...
Team-based prevention of catheter-related infectionsRichard P Wenzel
N Engl J Med 355:2781-3. 2006
Use of ethanol lock therapy to reduce the incidence of catheter-related bloodstream infections in home parenteral nutrition patientsMarianne T Opilla
Department of Nursing, Nutrishare, Inc, Elk Grove, California, USA
JPEN J Parenter Enteral Nutr 31:302-5. 2007..To reduce the incidence of infection in frequently infected HPN patients, prophylactic ethanol lock therapy (ELT) was initiated...
Hospital-acquired Clostridium difficile-associated disease in the intensive care unit setting: epidemiology, clinical course and outcomeAlexandre R Marra
Department of Infectious Diseases, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
BMC Infect Dis 7:42. 2007..We evaluated the epidemiology, clinical course and outcome of hospital-acquired CDAD in the critical care setting...
Patient-to-patient transmission of hepatitis C virusRichard P Wenzel
Ann Intern Med 142:940-1. 2005
Epidemiology of bloodstream infections in patients receiving long-term total parenteral nutritionAlexandre R Marra
Division of Infectious Diseases, Universidade Federal de São Paulo UNIFESP EPM Hospital São Paulo, Brazil
J Clin Gastroenterol 41:19-28. 2007..To describe the epidemiology and microbiologic characteristics of bloodstream infections (BSIs) in patients receiving long-term total parenteral nutrition (TPN)...
