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Species | Lindon J EavesSummaryAffiliation: Virginia Commonwealth University Country: USA Publications
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Publications
Genetic and environmental influences on the relative timing of pubertal changeLindon Eaves
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, Virginia 23298 0003, USA
Twin Res 7:471-81. 2004..0+/-3.6% in boys. Shared environmental influences account for 3.6+/-3.4% in girls and 0% in boys. In girls, nonshared environmental effects explain 0.1+/-0.1% of the total residual variance. The comparable figure in boys is 12.0+/-3.6%...- Parent-child feedback predicts sibling contrast: using twin studies to test theories of parent-offspring interaction in infant behaviorLindon J Eaves
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298, USA
Twin Res Hum Genet 8:1-4. 2005.... - Genotype x Environment interaction in psychopathology: fact or artifact?Lindon J Eaves
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, Virginia 23298, USA
Twin Res Hum Genet 9:1-8. 2006..There is therefore reason to question the biological significance of published findings... - Revisiting the children of twins: can they be used to resolve the environmental effects of dyadic parental treatment on child behavior?Lindon J Eaves
Virginia Institute of Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, Virginia 23298, USA
Twin Res Hum Genet 8:283-90. 2005..The fact that many candidate environments, such as parental divorce, are dyadic gives reason to question the interpretation of their correlations with behavior in the children of twins... - Application of Bayesian inference using Gibbs sampling to item-response theory modeling of multi-symptom genetic dataLindon Eaves
Virginia Institute for Psychiatric and Behavioral Genetics, Department of Human Genetics, Virginia Commonwealth University, Richmond, VA 23298 0003, USA
Behav Genet 35:765-80. 2005..Additional benefits of the IRT approach are discussed including the estimation of latent trait scores, including genetic factor scores, and their sampling errors... 
Flexible Mx specification of various extended twin kinship designsHermine H Maes
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298 0003, United States of America
Twin Res Hum Genet 12:26-34. 2009..Results indicate that biases in the estimation of variance components depend both on the types of relative available for analysis, and on the underlying genetic and environmental architecture of the phenotype of interest...- Genetic and cultural transmission of antisocial behavior: an extended twin parent modelHermine H Maes
Department of Human Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298 0003, USA
Twin Res Hum Genet 10:136-50. 2007..This study showed significant heritability, which is slightly increased by assortative mating, and significant effects of primarily nonparental shared environment on CD... - The impact of environmental experiences on symptoms of anxiety and depression across the life spanKenneth S Kendler
Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA
Psychol Sci 22:1343-52. 2011..By middle adulthood, environmental experiences contributed substantially to stable and predictable interindividual differences in levels of anxiety and depression... 
The mediating effect of parental neglect on adolescent and young adult anti-sociality: a longitudinal study of twins and their parentsLindon J Eaves
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, VA 23298, USA
Behav Genet 40:425-37. 2010..The longitudinal study of twins and their parents makes it possible to demonstrate there is a direct causal effect of childhood adversity on child conduct disorder over and above any indirect genetic correlation...- A twin study of genetic and environmental influences on tobacco initiation, regular tobacco use and nicotine dependenceHermine H Maes
Departments of Human Genetics and Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298 0003, USA
Psychol Med 34:1251-61. 2004..As the development of ND requires regular tobacco use (RTU) which in turn requires TI, a conditional approach is necessary... - Developmental-genetic effects on level and change in childhood fears of twins during adolescenceLindon J Eaves
Virginia Institute for Psychiatric and Behavioral Genetics, Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA 23298 0003, USA
J Child Psychol Psychiatry 49:1201-10. 2008.... - Childhood adversity, monoamine oxidase a genotype, and risk for conduct disorderDebra L Foley
Department of Human Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virgoinia Commonwaelth University, Richmond, 23298 0003, USA
Arch Gen Psychiatry 61:738-44. 2004..Very little is known about how different sets of risk factors interact to influence risk for psychiatric disorder... - Unraveling the effect of genes and environment in the transmission of parental antisocial behavior to children's conduct disturbance, depression and hyperactivityJudy L Silberg
Department of Human and Molecular Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298 0003, USA
J Child Psychol Psychiatry 53:668-77. 2012.... - Genetic and cultural transmission of smoking initiation: an extended twin kinship modelHermine H Maes
Department of Human Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, 980003, 23298 0003, Richmond, VA 23298 0003, USA
Behav Genet 36:795-808. 2006.... - Racial differences in genetic and environmental risk to preterm birthTimothy P York
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
PLoS ONE 5:e12391. 2010..This study provides a comprehensive description of the relative genetic and environmental contributions to racial differences in gestational age... - A longitudinal twin study of fears from middle childhood to early adulthood: evidence for a developmentally dynamic genomeKenneth S Kendler
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University Medical School, Box 980126, 800 E Leigh St, Room 1 123, Richmond, VA 23298 0126, USA
Arch Gen Psychiatry 65:421-9. 2008..While the nature of common fears changes over development, we do not know whether genetic effects on fear-proneness are developmentally stable or developmentally dynamic... - Modulation of gene expression by genetic and environmental heterogeneity in timing of a developmental milestoneLindon J Eaves
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, Virginia 23298-0003, USA
Behav Genet 33:1-6. 2003..The impact of these effects on age patterns in twin correlations is examined and their relevance to current data on developmental change discussed briefly... - Epistatic and environmental control of genome-wide gene expressionTimothy P York
Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia 23298 0003, USA
Twin Res Hum Genet 8:5-15. 2005.... - Familial influences on alcohol use in adolescent female twins: testing for genetic and environmental interactionsDonna R Miles
Department of Human Genetics, Virginia Commonwealth University, Virginia Institute for Psychiatric and Behavioral Genetics, P O Box 980003, 800 East Leigh St, Biotech One, Suite 100, Richmond, Virginia, 23298 0003, USA
J Stud Alcohol 66:445-51. 2005..The present study examined whether measures of family adaptability and cohesion may moderate the genetic influence on risk for alcohol use among female adolescents... - Markov Chain Monte Carlo approaches to analysis of genetic and environmental components of human developmental change and G x E interactionLindon Eaves
Virginia Institute for Psychiatric and Behavioral Genetics, Department of Human Genetics, Virginia Commonwealth University, PO Box 980003, Richmond, Virginia 23298-0003, USA
Behav Genet 33:279-99. 2003..Possible limitations of MCMC methods are discussed. Further studies are necessary explore the value of an approach that could extend the horizons of research in developmental genetic epidemiology... - Genetic and environmental influences on temperament in the first year of life: the Puerto Rico Infant Twin Study (PRINTS)Judy L Silberg
Virginia Institute for Psychiatric and Behavioral Genetics, Department of Human Genetics, Virginia Commonwealth University, Richmond, Virginia, USA
Twin Res Hum Genet 8:328-36. 2005..In contrast, a significant effect of the shared environment on the temperamental trait of unadaptability has not been reported previously... - Multivariate adaptive regression splines: a powerful method for detecting disease-risk relationship differences among subgroupsTimothy P York
Massey Cancer Center, Virginia Commonwealth University, Virginia Institute for Psychiatric and Behavioral Genetics, P O Box 980003, Richmond, VA 23298 0003, USA
Stat Med 25:1355-67. 2006..It was shown that power was higher even if the regression curve was linear, that gains increased with the complexity of the curve, and that for highly non-linear curves model-free methods such as MARS might be the only alternative... - Risks for conduct disorder symptoms associated with parental alcoholism in stepfather families versus intact families from a community sampleDebra L Foley
Department of Human Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA
J Child Psychol Psychiatry 45:687-96. 2004.... - Course and short-term outcomes of separation anxiety disorder in a community sample of twinsDebra L Foley
Human Genetics Department, Virginia Commonwealth University, Richmond 23298 0003, USA
J Am Acad Child Adolesc Psychiatry 43:1107-14. 2004..To assess the course and short-term outcomes associated with separation anxiety disorder (SAD) in a community setting... - Childhood separation anxiety disorder and adult onset panic attacks share a common genetic diathesisRoxann Roberson-Nay
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298, USA
Depress Anxiety 29:320-7. 2012.... - Genetic and environmental transmission of body mass index fluctuationJocilyn E Bergin
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, MCV, P O Box 980126, Richmond, VA 23298, USA
Behav Genet 42:867-74. 2012.... - Maternal smoking during pregnancy and risk to boys' conduct disturbance: an examination of the causal hypothesisJudy L Silberg
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298-0003, USA
Biol Psychiatry 53:130-5. 2003..Our results challenge previous findings of a direct effect of prenatal smoke exposure on risk to Cd once other etiologic factors are considered... - Genetic and environmental influences on the transmission of parental depression to children's depression and conduct disturbance: an extended Children of Twins studyJudy L Silberg
Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA, USA
J Child Psychol Psychiatry 51:734-44. 2010.... - Transmission of attitudes toward abortion and gay rights: effects of genes, social learning and mate selectionLindon J Eaves
Departments of Human Genetics and Psychiatry, Virginia Commonwealth University, Richmond, VA, USA
Behav Genet 38:247-56. 2008..By contrast, the choice of mate is a social action that has a marked impact on the polarization of social attitudes and on the long-term influence that parents exert upon the next generation... - Genetic and environmental risk factors in adolescent substance useJudy Silberg
Department of Human Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond 23298 0003, USA
J Child Psychol Psychiatry 44:664-76. 2003..The present study was undertaken with the goal of understanding the causes of association between substance use and both conduct disturbance (CD) and depression in adolescent boys and girls... - Resolving multiple epigenetic pathways to adolescent depressionLindon Eaves
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond 23298-0003, USA
J Child Psychol Psychiatry 44:1006-14. 2003..Additional genetic effects, specific to depression, further increase sensitivity to adversity. Failure to take into account the effects of G x E and rGE will lead to misunderstanding how genes and environment affect complex behavior... - Has the "Equal Environments" assumption been tested in twin studies?Lindon Eaves
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, Virginia 23298 0003, USA
Twin Res 6:486-9. 2003..The stratification approach to testing the equal environments assumption may be misleading and the results of such tests may actually be consistent with a simpler theory of the role of genetic factors in niche selection... - Informant disagreement for separation anxiety disorderDebra Foley
Human Genetics Department, Virginia Commonwealth University, Richmond 23298 0003, USA
J Am Acad Child Adolesc Psychiatry 43:452-60. 2004..To characterize informant disagreement for separation anxiety disorder (SAD)... - Etiological heterogeneity in the development of antisocial behavior: the Virginia Twin Study of Adolescent Behavioral Development and the Young Adult Follow-UpJudy L Silberg
Virginia Institute for Psychiatric and Behavioral Genetics, Department of Human Genetics, Virginia Commonwealth University, Richmond, VA 23298 0003, USA
Psychol Med 37:1193-202. 2007..Longitudinal, genetically informed, prospective data collected on a large population of male twins (n=1037) were used to examine developmental differences in the etiology of antisocial behavior... - The relationship between separation anxiety and impairmentDebra L Foley
Virginia Institute for Psychiatric and Behavioral Genetics, Medical College of Virginia Commonwealth University, USA
J Anxiety Disord 22:635-41. 2008..The results indicate that impairment may index current treatment need but symptom levels provide the best information about severity and prognosis... - Genetic and environmental effects on diurnal dehydroepiandrosterone sulfate concentrations in middle-aged menElizabeth C Prom-Wormley
Virginia Institute for Behavioral and Psychiatric Genetics, Virginia Commonwealth University, Richmond, VA 23298 0126, United States
Psychoneuroendocrinology 36:1441-52. 2011..The characterization of the genetic and environmental contributions to daily DHEAS concentrations is thus important for understanding the genetics of health and aging... - Evaluation of analyses of univariate discrete twin dataPatrick F Sullivan
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University Richmond, 23298 0126, USA
Behav Genet 32:221-7. 2002..These results suggest that the use of AIC to guide twin modeling for univariate discrete traits should either be abandoned or used with great caution... - Estimating fetal and maternal genetic contributions to premature birth from multiparous pregnancy histories of twins using MCMC and maximum-likelihood approachesTimothy P York
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, Virginia 32398 0003, United States of America
Twin Res Hum Genet 12:333-42. 2009..We anticipate the flexibility of MCMC methods to handle increasingly complex models to be of particular relevance for the study of birth outcomes... - Assessment of the within-family environment in twins: absolute versus differential ratings, and relationship with conduct problemsRene Carbonneau
Virginia Institute for Psychiatric and Behavioral Genetics, USA
J Child Psychol Psychiatry 43:1064-74. 2002..The aim was to compare the psychometric properties of absolute versus differential ratings of the within-family environments and to examine their associations with conduct problems in 8-16-year-old twins... - Epistasis between COMT and MTHFR in maternal-fetal dyads increases risk for preeclampsiaLori D Hill
Department of Obstetrics and Gynecology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
PLoS ONE 6:e16681. 2011..341 and P = 0.219, respectively). Our findings demonstrate a role for both maternal and fetal COMT in preeclampsia and highlight the importance of including allelic variation in MTHFR... - cDNA microarray analysis identifies genes induced in common by peptide growth factors and androgen in human prostate epithelial cellsTimothy P York
Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia 23298, USA
Mol Carcinog 44:242-51. 2005..These results provide comprehensive and unique insights into potential mechanisms by which peptide growth factors provide alternate pathways to control prostate epithelial cell proliferation in malignant states... - Putting the 'human' back in genetics: modeling the extended kinships of twinsLindon Eaves
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
Twin Res Hum Genet 12:1-7. 2009.... - The phenotype of persons having mosaicism for trisomy 21/Down syndrome reflects the percentage of trisomic cells present in different tissuesPaulie Papavassiliou
Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Virginia 23298 0662, USA
Am J Med Genet A 149:573-83. 2009..The results of this study should enable geneticists and other health care professionals to provide information regarding optimal diagnostic approaches and anticipated clinical outcomes... - A Children of Twins Study of parental divorce and offspring psychopathologyBrian M D'Onofrio
Department of Psychological and Brain Sciences, Indiana University 47405, USA
J Child Psychol Psychiatry 48:667-75. 2007..The relations may be due to genetic or environmental selection factors, characteristics that lead to both marital separation and offspring functioning... - Genetics of verbal working memory processes: a twin study of middle-aged menWilliam S Kremen
Department of Psychiatry, Center for Behavioral Genomics, University of California, San Diego, CA 92093 0738, USA
Neuropsychology 21:569-80. 2007..The genetic influences that were specific to reading span were concluded to most likely reflect an executive function component. Implications for genetic studies of aging and prefrontal brain function are discussed... - Analysis and interpretation of twin studies including measures of the shared environmentEric Turkheimer
Department of Psychology, University of Virginia, Charlottesville 22904 4400, USA
Child Dev 76:1217-33. 2005.... - Genetic and environmental influences on individual differences in attitudes toward homosexuality: an Australian twin studyKarin J H Verweij
Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, 300 Herston Road, Brisbane 4029, QLD, Australia
Behav Genet 38:257-65. 2008..The results suggest that variation in attitudes toward homosexuality is substantially inherited, and that social environmental influences are relatively minor... - The role of the children of twins design in elucidating causal relations between parent characteristics and child outcomesBrian M D'Onofrio
Department of Psychology, University of Virginia, Charlottesville 22904 4400, USA
J Child Psychol Psychiatry 44:1130-44. 2003..This paper discusses the strength of the Children of Twins (COT) design to highlight the role of specific environments... - Storage and executive components of working memory: integrating cognitive psychology and behavior genetics in the study of agingWilliam S Kremen
Department of Psychiatry, Center for Behavioral Genomics, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, USA
J Gerontol B Psychol Sci Soc Sci 63:P84-91. 2008..We discuss the findings in the context of research suggesting that new genetic influences come into play if demand continues to increase beyond a certain threshold, a threshold that may change with task difficulty and with age...