Research Topics
| Marjolein de WitSummaryAffiliation: Virginia Commonwealth University Country: USA Publications
|
Detail Information
Publications
Alcohol-use disorders in the critically ill patientMarjolein de Wit
Division of Pulmonary Disease and Critical Care Medicine, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA 23298 0050, USA
Chest 138:994-1003. 2010..AUDs are underdiagnosed, and a first step to improving patient outcomes may lie in systematically and accurately identifying AUDs...
Randomized trial comparing daily interruption of sedation and nursing-implemented sedation algorithm in medical intensive care unit patientsMarjolein de Wit
Pulmonary and Critical Care Division, Department of Internal Medicine, School of Medicine, Virginia Commonwealth University, PO Box 980050, Richmond, VA 23298 0050, USA
Crit Care 12:R70. 2008..Daily interruption of sedation (DIS) and sedation algorithms (SAs) have been shown to decrease mechanical ventilation (MV) duration. We conducted a randomized study comparing these strategies...
Drug withdrawal, cocaine and sedative use disorders increase the need for mechanical ventilation in medical patientsMarjolein de Wit
Division of Pulmonary Disease and Critical Care Medicine, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, USA
Addiction 103:1500-8. 2008..The objective of this study is to determine if the presence of DUD and drug withdrawal syndromes are associated with increased need for MV in medical patients...
Ineffective triggering predicts increased duration of mechanical ventilationMarjolein de Wit
Division of Pulmonary Disease and Critical Care Medicine, Virginia Commonwealth University, Richmond, VA, USA
Crit Care Med 37:2740-5. 2009..To determine whether high rates of ineffective triggering within the first 24 hrs of mechanical ventilation (MV) are associated with longer MV duration and shorter ventilator-free survival (VFS)...
Outcomes of patients with alcohol use disorders experiencing healthcare-associated infectionsMarjolein de Wit
Division of Pulmonary Disease and Critical Care Medicine, Department of Internal Medicine, School of Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA
Alcohol Clin Exp Res 35:1368-73. 2011..HAI have been shown to substantially increase the hospital length of stay, mortality, and cost. In a cohort of patients with HAI, we sought to determine mortality, cost, and hospital length of stay attributable to AUD...
Relationship between alcohol use disorders, cortisol concentrations, and cytokine levels in patients with sepsisMarjolein de Wit
Division of Pulmonary Disease and Critical Care Medicine, Department of Internal Medicine, Virginia Commonwealth University, 1200 East Broad Street, Richmond, VA 23298 0050, USA
Crit Care 14:R230. 2010..The relationship between AUD and cortisol in septic patients is unknown. We aimed to study this relationship and postulated that AUD would be associated with higher cortisol and anti-inflammatory cytokine profile...
Monitoring of patient-ventilator interaction at the bedsideMarjolein de Wit
Division of Pulmonary Disease and Critical Care Medicine, Department of Internal Medicine, Virginia Commonwealth University, Post Office Box 980050, Richmond VA 23298 0050, USA
Respir Care 56:61-72. 2011..Various waveforms are displayed and graphically demonstrate asynchronies; basic principles of waveform interpretation are discussed...
Alcohol use disorders increase the risk for mechanical ventilation in medical patientsMarjolein de Wit
Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Virginia Commonwealth University, Richmond, VA 23298 0050, USA
Alcohol Clin Exp Res 31:1224-30. 2007....
Observational study of patient-ventilator asynchrony and relationship to sedation levelMarjolein de Wit
Division of Pulmonary Disease and Critical Care Medicine, Department of Internal Medicine, Virginia Commonwealth University, Box 980050, Richmond, VA 23298 0050, USA
J Crit Care 24:74-80. 2009..Clinicians frequently administer sedation to facilitate mechanical ventilation. The purpose of this study was to examine the relationship between sedation level and patient-ventilator asynchrony...
Health care-associated infections in surgical patients undergoing elective surgery: are alcohol use disorders a risk factor?Marjolein de Wit
Division of Pulmonary Disease and Critical Care Medicine, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA 23298 0050, USA
J Am Coll Surg 215:229-36. 2012..We sought to determine the risk of HAI and SSI in surgical patients undergoing elective inpatient joint replacement, coronary artery bypass grafting, laparoscopic cholecystectomy, colectomy, and hernia repair...
Administration of sedatives and level of sedation: comparative evaluation via the Sedation-Agitation Scale and the Bispectral IndexMarjolein de Wit
Pulmonary and Critical Care Division, New England Medical Center, Tufts University School of Medicine, Boston, Mass, USA
Am J Crit Care 12:343-8. 2003..Use of continuous infusions is associated with deeper levels of sedation, and patients receiving continuous infusions are more likely to be oversedated. Sedation therapy should be guided by subjective or objective assessment...
Accuracy of previous estimates for adult prolonged acute mechanical ventilation volume in 2020: update using 2000-2008 dataMarya D Zilberberg
School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA, USA
Crit Care Med 40:18-20. 2012..With 2006-2008 data becoming available, we explored the precision of our previous formulas and estimates...
