Wenxiang Cong

Summary

Affiliation: Virginia Polytechnic Institute and State University
Country: USA

Publications

  1. ncbi request reprint Numerical study on the validity of the diffusion approximation for computational optical biopsy
    Haiou Shen
    Department of Radiology, University of Iowa, Iowa City, Iowa 52242, USA
    J Opt Soc Am A Opt Image Sci Vis 24:423-9. 2007
  2. doi request reprint X-ray dark-field imaging modeling
    W Cong
    Biomedical Imaging Division, School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA
    J Opt Soc Am A Opt Image Sci Vis 29:908-12. 2012
  3. doi request reprint Differential phase-contrast interior tomography
    Wenxiang Cong
    Biomedical Imaging Division, School of Biomedical Engineering and Sciences, Virginia Tech, Blacksburg, VA 24061, USA
    Phys Med Biol 57:2905-14. 2012
  4. doi request reprint X-ray scattering tomography for biological applications
    W Cong
    Biomedical Imaging Division, VT WFU School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA
    J Xray Sci Technol 19:219-27. 2011
  5. pmc Higher-order phase shift reconstruction approach
    Wenxiang Cong
    Biomedical Imaging Division, School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA
    Med Phys 37:5238-42. 2010
  6. ncbi request reprint Flux vector formulation for photon propagation in the biological tissue
    W Cong
    Biomedical Imaging Division, School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, VA 24061, USA
    Opt Lett 32:2837-9. 2007
  7. pmc Bioluminescence tomography based on the phase approximation model
    W Cong
    Biomedical Imaging Division, School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Stanger Street, Blacksburg, Virginia 24061, USA
    J Opt Soc Am A Opt Image Sci Vis 27:174-9. 2010
  8. pmc Integral equations of the photon fluence rate and flux based on a generalized Delta-Eddington phase function
    Wenxiang Cong
    Virginia Polytechnic Institute and State University, Biomedical Imaging Division, School of Biomedical Engineering and Sciences, 1880 Pratt Drive, Blacksburg, Virginia 24061, USA
    J Biomed Opt 13:024016. 2008
  9. pmc Differential evolution approach for regularized bioluminescence tomography
    Alexander Cong
    Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA 24060, USA
    IEEE Trans Biomed Eng 57:2229-38. 2010
  10. ncbi request reprint Digital spectral separation methods and systems for bioluminescence imaging
    Ge Wang
    1School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, 1880 Pratt Dr Suite 2000 Blacksburg, VA 24060, USA
    Opt Express 16:1719-32. 2008

Research Grants

Collaborators

Detail Information

Publications27

  1. ncbi request reprint Numerical study on the validity of the diffusion approximation for computational optical biopsy
    Haiou Shen
    Department of Radiology, University of Iowa, Iowa City, Iowa 52242, USA
    J Opt Soc Am A Opt Image Sci Vis 24:423-9. 2007
    ..Furthermore, an approximate formula is given to describe the measurement of a cut-end fiber probe for a ball source...
  2. doi request reprint X-ray dark-field imaging modeling
    W Cong
    Biomedical Imaging Division, School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA
    J Opt Soc Am A Opt Image Sci Vis 29:908-12. 2012
    ..The numerical simulations and phantom experiments have demonstrated the accuracy and practicability of the proposed model...
  3. doi request reprint Differential phase-contrast interior tomography
    Wenxiang Cong
    Biomedical Imaging Division, School of Biomedical Engineering and Sciences, Virginia Tech, Blacksburg, VA 24061, USA
    Phys Med Biol 57:2905-14. 2012
    ..Then, we develop a practical iterative algorithm for such an interior reconstruction and perform numerical experiments to demonstrate the feasibility of the proposed approach...
  4. doi request reprint X-ray scattering tomography for biological applications
    W Cong
    Biomedical Imaging Division, VT WFU School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA
    J Xray Sci Technol 19:219-27. 2011
    ..In this paper, we develop a scattering imaging approach to reconstruct the electron density distribution of an object and demonstrate its feasibility in the numerical simulation...
  5. pmc Higher-order phase shift reconstruction approach
    Wenxiang Cong
    Biomedical Imaging Division, School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA
    Med Phys 37:5238-42. 2010
    ..Such x-ray refractive index images can reveal structural features in soft tissues, with excellent resolution differentiating healthy and malignant tissues...
  6. ncbi request reprint Flux vector formulation for photon propagation in the biological tissue
    W Cong
    Biomedical Imaging Division, School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, VA 24061, USA
    Opt Lett 32:2837-9. 2007
    ..The methodology is validated in the Monte Carlo simulation and can be applied in various optical imaging applications...
  7. pmc Bioluminescence tomography based on the phase approximation model
    W Cong
    Biomedical Imaging Division, School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Stanger Street, Blacksburg, Virginia 24061, USA
    J Opt Soc Am A Opt Image Sci Vis 27:174-9. 2010
    ..The numerical simulation and phantom experiments demonstrate the feasibility of the proposed approach...
  8. pmc Integral equations of the photon fluence rate and flux based on a generalized Delta-Eddington phase function
    Wenxiang Cong
    Virginia Polytechnic Institute and State University, Biomedical Imaging Division, School of Biomedical Engineering and Sciences, 1880 Pratt Drive, Blacksburg, Virginia 24061, USA
    J Biomed Opt 13:024016. 2008
    ..By comparing to the Monte Carlo simulation results, the solutions of the system of integral equations accurately model the photon propagation in biological tissue over a wide range of optical parameters...
  9. pmc Differential evolution approach for regularized bioluminescence tomography
    Alexander Cong
    Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA 24060, USA
    IEEE Trans Biomed Eng 57:2229-38. 2010
    ..Then, we evaluate this novel approach in numerical, phantom, and mouse studies...
  10. ncbi request reprint Digital spectral separation methods and systems for bioluminescence imaging
    Ge Wang
    1School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, 1880 Pratt Dr Suite 2000 Blacksburg, VA 24060, USA
    Opt Express 16:1719-32. 2008
    ..This approach also permits recovery of the bioluminescent signal time course, which is useful to study the kinetics of multiple bioluminescent probes using multi-spectral bioluminescence tomography (MSBT)...
  11. ncbi request reprint Overview of bioluminescence tomography--a new molecular imaging modality
    Ge Wang
    Bioluminescence Tomography Laboratory, VT WFU School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, 1880 Pratt Drive, Suite 2000, MC 0493, Blacksburg, VA 24061, USA
    Front Biosci 13:1281-93. 2008
    ....
  12. pmc Spectrally resolving and scattering-compensated x-ray luminescence/fluorescence computed tomography
    Wenxiang Cong
    Virginia Polytechnic Institute and State University, School of Biomedical Engineering and Sciences, Biomedical Imaging Division, Blacksburg, Virginia 24061, USA
    J Biomed Opt 16:066014. 2011
    ..The numerical simulation results demonstrate the feasibility and merits of the proposed approach...
  13. doi request reprint X-ray fluorescence tomographic system design and image reconstruction
    Wenxiang Cong
    School of Biomedical Engineering and Sciences, Virginia Tech, Blacksburg, VA, USA
    J Xray Sci Technol 21:1-8. 2013
    ..The x-ray fluorescence computed tomography is an important molecular imaging tool. It can be used directly in samall animal research. It has great translational potential for future clinical applications...
  14. pmc Improving the accuracy of the diffusion model in highly absorbing media
    Alexander X Cong
    Biomedical Imaging Division, School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, 1880 Pratt Drive, Blacksburg, VA 24061, USA
    Int J Biomed Imaging 2007:38168. 2007
    ..The effectiveness of the proposed technique was demonstrated by the numerical experiments using the Monte Carlo simulation data as measurements...
  15. ncbi request reprint Dynamic bowtie for fan-beam CT
    Fenglin Liu
    Engineering Research Center of Industrial Computed Tomography Nondestructive Testing, Key Lab of Optoelectronic Technology and System, Ministry of Education, Chongqing University, Chongqing, China School of Biomedical Engineering and Sciences, Virginia Tech, Blacksburg, VA, USA
    J Xray Sci Technol 21:579-90. 2013
    ..Furthermore, our design methodology can be applied to specify an optimized dynamic bowtie for any cross-section of a patient, preferably using rapid prototyping technology. ..
  16. doi request reprint Fourier transform-based iterative method for differential phase-contrast computed tomography
    Wenxiang Cong
    School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA
    Opt Lett 37:1784-6. 2012
    ..Numerical simulation and biological sample experiments demonstrate the merits of the proposed approach...
  17. pmc Towards omni-tomography--grand fusion of multiple modalities for simultaneous interior tomography
    Ge Wang
    Biomedical Imaging Division, VT WFU School of Biomedical Engineering and Sciences, Blacksburg, Virginia Tech, Blacksburg, Virginia, United States of America
    PLoS ONE 7:e39700. 2012
    ..To address this challenge, omni-tomography is now unveiled as an emerging direction for biomedical imaging and systems biomedicine...
  18. pmc Monte Carlo fluorescence microtomography
    Alexander X Cong
    Virginia Tech, School of Biomedical Engineering and Sciences, Biomedical Imaging Division, Blacksburg, Virginia 24061Virginia Tech, Center for Photonics Technology, Bradley Department of Electrical and Computer Engineering, Blacksburg, Virginia 24061
    J Biomed Opt 16:070501. 2011
    ..Our studies on biomimetic tissue scaffolds have demonstrated that the proposed approach is capable of localizing and quantifying the distribution of optical molecular probe accurately and reliably...
  19. pmc Varying collimation for dark-field extraction
    Ge Wang
    SBES Division ICTAS Center for Biomedical Imaging, VT WFU School of Biomedical Engineering, Virginia Tech, Blacksburg, VA 24061, USA
    Int J Biomed Imaging 2009:847537. 2009
    ..The results show that the acquired dark field signals can clearly reveal the structural information of tissues in terms of Rayleigh scattering characteristics...
  20. pmc Optimization of K-edge imaging with spectral CT
    Peng He
    Chongqing University, Chongqing, China
    Med Phys 39:6572-9. 2012
    ..K-edge imaging involves the two energy bins on both sides of a K-edge. The authors propose a K-edge imaging optimization model to determine these two energy bins...
  21. ncbi request reprint A born-type approximation method for bioluminescence tomography
    Wenxiang Cong
    Bioluminescence Tomography Laboratory, Department of Radiology, University of Iowa, Iowa City, Iowa 52242, USA
    Med Phys 33:679-86. 2006
    ..The BLT reconstruction is formulated in a linear least-squares optimization framework with simple bounds constraint. The performance of this method is evaluated in numerical simulation and phantom experiments...
  22. ncbi request reprint Boundary integral method for bioluminescence tomography
    Wenxiang Cong
    J Biomed Opt 11:020503. 2006
    ..The feasibility of the proposed BLT algorithm is demonstrated in heterogeneous mouse chest phantom studies...
  23. ncbi request reprint A mouse optical simulation environment (MOSE) to investigate bioluminescent phenomena in the living mouse with the Monte Carlo method
    Hui Li
    Medical Image Processing Group, Key Laboratory of Complex Systems and Intelligence Science, Institute of Automation, Chinese Academy of Science, Beijing, China
    Acad Radiol 11:1029-38. 2004
    ..This simulator is dedicated to small animal optical imaging based on bioluminescence...
  24. ncbi request reprint Spectrally resolved bioluminescence tomography with adaptive finite element analysis: methodology and simulation
    Yujie Lv
    Medical Image Processing Group, Institute of Automation, Chinese Academy of Sciences, PO Box 2728, Beijing 100080, People s Republic of China
    Phys Med Biol 52:4497-512. 2007
    ..In terms of optical property errors and two sources of discernment in deeper positions, this BLT algorithm represents the unique predominance for BLT reconstruction...
  25. ncbi request reprint MicroCT-guided bioluminescence tomography based on the adaptive finite element tomographic algorithm
    Yujie Lv
    Medical Image Processing Group, Chinese Academy of Science, Beijing, China
    Conf Proc IEEE Eng Med Biol Soc 1:381-4. 2006
    ..Finally, simulation results with the above framework demonstrate the effectiveness and potential of the proposed adaptive tomographic algorithm...
  26. pmc Formulation of photon diffusion from spherical bioluminescent sources in an infinite homogeneous medium
    Wenxiang Cong
    CT Micro CT Laboratory University of Iowa Iowa City, Iowa 52242, USA
    Biomed Eng Online 3:12. 2004
    ..The numerical solutions to the diffusion equation take large amounts of computational time, and the studies for its analytic solutions have attracted more attention in biomedical engineering applications...

Research Grants3

  1. Mouse Modeling Techniques for Bioluminescence Tomography
    Wenxiang Cong; Fiscal Year: 2007
    ..Upon the completion of this project, the proposed mouse modeling techniques will have been validated, and the associated gains in BLT image reconstruction will have been quantified in terms of source centroid and total energy. ..
  2. Mouse Modeling Techniques for Bioluminescence Tomography
    Wenxiang Cong; Fiscal Year: 2006
    ..Upon the completion of this project, the proposed mouse modeling techniques will have been validated, and the associated gains in BLT image reconstruction will have been quantified in terms of source centroid and total energy. ..