Research Topics
| Wenxiang CongSummaryAffiliation: Virginia Polytechnic Institute and State University Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
Numerical study on the validity of the diffusion approximation for computational optical biopsyHaiou Shen
Department of Radiology, University of Iowa, Iowa City, Iowa 52242, USA
J Opt Soc Am A Opt Image Sci Vis 24:423-9. 2007..Furthermore, an approximate formula is given to describe the measurement of a cut-end fiber probe for a ball source...
X-ray dark-field imaging modelingW Cong
Biomedical Imaging Division, School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA
J Opt Soc Am A Opt Image Sci Vis 29:908-12. 2012..The numerical simulations and phantom experiments have demonstrated the accuracy and practicability of the proposed model...- Differential phase-contrast interior tomographyWenxiang Cong
Biomedical Imaging Division, School of Biomedical Engineering and Sciences, Virginia Tech, Blacksburg, VA 24061, USA
Phys Med Biol 57:2905-14. 2012..Then, we develop a practical iterative algorithm for such an interior reconstruction and perform numerical experiments to demonstrate the feasibility of the proposed approach... 
Bioluminescence tomography based on the phase approximation modelW Cong
Biomedical Imaging Division, School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Stanger Street, Blacksburg, Virginia 24061, USA
J Opt Soc Am A Opt Image Sci Vis 27:174-9. 2010..The numerical simulation and phantom experiments demonstrate the feasibility of the proposed approach...- Integral equations of the photon fluence rate and flux based on a generalized Delta-Eddington phase functionWenxiang Cong
Virginia Polytechnic Institute and State University, Biomedical Imaging Division, School of Biomedical Engineering and Sciences, 1880 Pratt Drive, Blacksburg, Virginia 24061, USA
J Biomed Opt 13:024016. 2008..By comparing to the Monte Carlo simulation results, the solutions of the system of integral equations accurately model the photon propagation in biological tissue over a wide range of optical parameters... - Flux vector formulation for photon propagation in the biological tissueW Cong
Biomedical Imaging Division, School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, VA 24061, USA
Opt Lett 32:2837-9. 2007..The methodology is validated in the Monte Carlo simulation and can be applied in various optical imaging applications... - Higher-order phase shift reconstruction approachWenxiang Cong
Biomedical Imaging Division, School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA
Med Phys 37:5238-42. 2010..Such x-ray refractive index images can reveal structural features in soft tissues, with excellent resolution differentiating healthy and malignant tissues... - X-ray scattering tomography for biological applicationsW Cong
Biomedical Imaging Division, VT WFU School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA
J Xray Sci Technol 19:219-27. 2011..In this paper, we develop a scattering imaging approach to reconstruct the electron density distribution of an object and demonstrate its feasibility in the numerical simulation... - Differential evolution approach for regularized bioluminescence tomographyAlexander Cong
Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA 24060, USA
IEEE Trans Biomed Eng 57:2229-38. 2010..Then, we evaluate this novel approach in numerical, phantom, and mouse studies... - Digital spectral separation methods and systems for bioluminescence imagingGe Wang
1School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, 1880 Pratt Dr Suite 2000 Blacksburg, VA 24060, USA
Opt Express 16:1719-32. 2008..This approach also permits recovery of the bioluminescent signal time course, which is useful to study the kinetics of multiple bioluminescent probes using multi-spectral bioluminescence tomography (MSBT)... - Overview of bioluminescence tomography--a new molecular imaging modalityGe Wang
Bioluminescence Tomography Laboratory, VT WFU School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, 1880 Pratt Drive, Suite 2000, MC 0493, Blacksburg, VA 24061, USA
Front Biosci 13:1281-93. 2008.... - Spectrally resolving and scattering-compensated x-ray luminescence/fluorescence computed tomographyWenxiang Cong
Virginia Polytechnic Institute and State University, School of Biomedical Engineering and Sciences, Biomedical Imaging Division, Blacksburg, Virginia 24061, USA
J Biomed Opt 16:066014. 2011..The numerical simulation results demonstrate the feasibility and merits of the proposed approach... - Improving the accuracy of the diffusion model in highly absorbing mediaAlexander X Cong
Biomedical Imaging Division, School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, 1880 Pratt Drive, Blacksburg, VA 24061, USA
Int J Biomed Imaging 2007:38168. 2007..The effectiveness of the proposed technique was demonstrated by the numerical experiments using the Monte Carlo simulation data as measurements... - X-ray fluorescence tomographic system design and image reconstructionWenxiang Cong
School of Biomedical Engineering and Sciences, Virginia Tech, Blacksburg, VA, USA
J Xray Sci Technol 21:1-8. 2013..The x-ray fluorescence computed tomography is an important molecular imaging tool. It can be used directly in samall animal research. It has great translational potential for future clinical applications... - Fourier transform-based iterative method for differential phase-contrast computed tomographyWenxiang Cong
School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA
Opt Lett 37:1784-6. 2012..Numerical simulation and biological sample experiments demonstrate the merits of the proposed approach... - Towards omni-tomography--grand fusion of multiple modalities for simultaneous interior tomographyGe Wang
Biomedical Imaging Division, VT WFU School of Biomedical Engineering and Sciences, Blacksburg, Virginia Tech, Blacksburg, Virginia, United States of America
PLoS ONE 7:e39700. 2012..To address this challenge, omni-tomography is now unveiled as an emerging direction for biomedical imaging and systems biomedicine... - Varying collimation for dark-field extractionGe Wang
SBES Division ICTAS Center for Biomedical Imaging, VT WFU School of Biomedical Engineering, Virginia Tech, Blacksburg, VA 24061, USA
Int J Biomed Imaging 2009:847537. 2009..The results show that the acquired dark field signals can clearly reveal the structural information of tissues in terms of Rayleigh scattering characteristics... - Monte Carlo fluorescence microtomographyAlexander X Cong
Virginia Tech, School of Biomedical Engineering and Sciences, Biomedical Imaging Division, Blacksburg, Virginia 24061Virginia Tech, Center for Photonics Technology, Bradley Department of Electrical and Computer Engineering, Blacksburg, Virginia 24061
J Biomed Opt 16:070501. 2011..Our studies on biomimetic tissue scaffolds have demonstrated that the proposed approach is capable of localizing and quantifying the distribution of optical molecular probe accurately and reliably... - Optimization of K-edge imaging with spectral CTPeng He
Chongqing University, Chongqing, China
Med Phys 39:6572-9. 2012..K-edge imaging involves the two energy bins on both sides of a K-edge. The authors propose a K-edge imaging optimization model to determine these two energy bins... - MicroCT-guided bioluminescence tomography based on the adaptive finite element tomographic algorithmYujie Lv
Medical Image Processing Group, Chinese Academy of Science, Beijing, China
Conf Proc IEEE Eng Med Biol Soc 1:381-4. 2006..Finally, simulation results with the above framework demonstrate the effectiveness and potential of the proposed adaptive tomographic algorithm... - A mouse optical simulation environment (MOSE) to investigate bioluminescent phenomena in the living mouse with the Monte Carlo methodHui Li
Medical Image Processing Group, Key Laboratory of Complex Systems and Intelligence Science, Institute of Automation, Chinese Academy of Science, Beijing, China
Acad Radiol 11:1029-38. 2004..With graduate refinements and enhancements, it is hoped that the MOSE will become a standard tool for bioluminescence tomography... - Boundary integral method for bioluminescence tomographyWenxiang Cong
J Biomed Opt 11:020503. 2006..The feasibility of the proposed BLT algorithm is demonstrated in heterogeneous mouse chest phantom studies... - A born-type approximation method for bioluminescence tomographyWenxiang Cong
Bioluminescence Tomography Laboratory, Department of Radiology, University of Iowa, Iowa City, Iowa 52242, USA
Med Phys 33:679-86. 2006..The BLT reconstruction is formulated in a linear least-squares optimization framework with simple bounds constraint. The performance of this method is evaluated in numerical simulation and phantom experiments... - Spectrally resolved bioluminescence tomography with adaptive finite element analysis: methodology and simulationYujie Lv
Medical Image Processing Group, Institute of Automation, Chinese Academy of Sciences, PO Box 2728, Beijing 100080, People s Republic of China
Phys Med Biol 52:4497-512. 2007..In terms of optical property errors and two sources of discernment in deeper positions, this BLT algorithm represents the unique predominance for BLT reconstruction... - Formulation of photon diffusion from spherical bioluminescent sources in an infinite homogeneous mediumWenxiang Cong
CT Micro CT Laboratory University of Iowa Iowa City, Iowa 52242, USA
Biomed Eng Online 3:12. 2004..The numerical solutions to the diffusion equation take large amounts of computational time, and the studies for its analytic solutions have attracted more attention in biomedical engineering applications...
Research Grants
- Mouse Modeling Techniques for Bioluminescence TomographyWenxiang Cong; Fiscal Year: 2007..Upon the completion of this project, the proposed mouse modeling techniques will have been validated, and the associated gains in BLT image reconstruction will have been quantified in terms of source centroid and total energy. ..