Shaunna L Clark

Summary

Affiliation: Virginia Commonwealth University
Country: USA

Publications

  1. pmc Genome-wide association study of patient-rated and clinician-rated global impression of severity during antipsychotic treatment
    Shaunna L Clark
    Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23298 0581, USA
    Pharmacogenet Genomics 23:69-77. 2013
  2. pmc Pharmacogenomic study of side-effects for antidepressant treatment options in STAR*D
    S L Clark
    Center for Biomarker Research and Personalized Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA 23298 0581, USA
    Psychol Med 42:1151-62. 2012
  3. pmc Analysis of efficacy and side effects in CATIE demonstrates drug response subgroups and potential for personalized medicine
    Shaunna L Clark
    Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA 23298 0581, USA
    Schizophr Res 132:114-20. 2011
  4. pmc Genotype-based ancestral background consistently predicts efficacy and side effects across treatments in CATIE and STAR*D
    DANIEL E ADKINS
    Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA, USA
    PLoS ONE 8:e55239. 2013
  5. pmc A methylome-wide study of aging using massively parallel sequencing of the methyl-CpG-enriched genomic fraction from blood in over 700 subjects
    Joseph L McClay
    Center for Biomarker Research and Personalized Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA
    Hum Mol Genet 23:1175-85. 2014
  6. pmc Refinement of schizophrenia GWAS loci using methylome-wide association data
    Gaurav Kumar
    Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Virginia Commonwealth University, McGuire Hall, Room 219, P O Box 980533, Richmond, VA, 23298 0581, USA
    Hum Genet 134:77-87. 2015
  7. doi Genome-Wide Meta-Analysis of Longitudinal Alcohol Consumption Across Youth and Early Adulthood
    DANIEL E ADKINS
    Center for Biomarker Research and Personalized Medicine, Virginia Commonwealth University, School of Pharmacy, Richmond, Virginia, USA
    Twin Res Hum Genet 18:335-47. 2015
  8. pmc MBD-seq as a cost-effective approach for methylome-wide association studies: demonstration in 1500 case--control samples
    Karolina A Aberg
    Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA
    Epigenomics 4:605-21. 2012

Detail Information

Publications8

  1. pmc Genome-wide association study of patient-rated and clinician-rated global impression of severity during antipsychotic treatment
    Shaunna L Clark
    Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23298 0581, USA
    Pharmacogenet Genomics 23:69-77. 2013
    ..To examine the unique and congruent findings between multiple raters in a genome-wide association study (GWAS) in the context of understanding individual differences in treatment response during antipsychotic therapy for schizophrenia...
  2. pmc Pharmacogenomic study of side-effects for antidepressant treatment options in STAR*D
    S L Clark
    Center for Biomarker Research and Personalized Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA 23298 0581, USA
    Psychol Med 42:1151-62. 2012
    ..Understanding individual differences in susceptibility to antidepressant therapy side-effects is essential to optimize the treatment of depression...
  3. pmc Analysis of efficacy and side effects in CATIE demonstrates drug response subgroups and potential for personalized medicine
    Shaunna L Clark
    Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA 23298 0581, USA
    Schizophr Res 132:114-20. 2011
    ..This study aims to improve understanding of antipsychotic non/response and assess the potential for personalized schizophrenia treatment...
  4. pmc Genotype-based ancestral background consistently predicts efficacy and side effects across treatments in CATIE and STAR*D
    DANIEL E ADKINS
    Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA, USA
    PLoS ONE 8:e55239. 2013
    ..As relatively few new psychiatric drugs are currently under development, such personalized medicine offers a promising approach toward optimizing pharmacotherapy for psychiatric conditions...
  5. pmc A methylome-wide study of aging using massively parallel sequencing of the methyl-CpG-enriched genomic fraction from blood in over 700 subjects
    Joseph L McClay
    Center for Biomarker Research and Personalized Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA
    Hum Mol Genet 23:1175-85. 2014
    ....
  6. pmc Refinement of schizophrenia GWAS loci using methylome-wide association data
    Gaurav Kumar
    Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Virginia Commonwealth University, McGuire Hall, Room 219, P O Box 980533, Richmond, VA, 23298 0581, USA
    Hum Genet 134:77-87. 2015
    ..Several hypotheses involved possible variation in transcription factor-binding efficiencies. ..
  7. doi Genome-Wide Meta-Analysis of Longitudinal Alcohol Consumption Across Youth and Early Adulthood
    DANIEL E ADKINS
    Center for Biomarker Research and Personalized Medicine, Virginia Commonwealth University, School of Pharmacy, Richmond, Virginia, USA
    Twin Res Hum Genet 18:335-47. 2015
    ..These findings underscore the value of combining longitudinal behavioral data and genome-wide genotype information in order to study developmental patterns and improve statistical power in genomic studies...
  8. pmc MBD-seq as a cost-effective approach for methylome-wide association studies: demonstration in 1500 case--control samples
    Karolina A Aberg
    Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA
    Epigenomics 4:605-21. 2012
    ..We studied the use of methyl-CpG binding domain (MBD) protein-enriched genome sequencing (MBD-seq) as a cost-effective screening tool for methylome-wide association studies (MWAS)...