G A Cabral

Summary

Affiliation: Virginia Commonwealth University
Country: USA

Publications

  1. ncbi request reprint Drugs and immunity: cannabinoids and their role in decreased resistance to infectious disease
    G A Cabral
    Department of Microbiology and Immunology, Medical College of Virginia Virginia Commonwealth University, Richmond 23298 0678, USA
    J Neuroimmunol 83:116-23. 1998
  2. ncbi request reprint Immunohistochemical localization of the neural cannabinoid receptor in rat brain
    D A Pettit
    Department of Pharmacology Toxicology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298 0678, USA
    J Neurosci Res 51:391-402. 1998
  3. ncbi request reprint Cannabinoid inhibition of the processing of intact lysozyme by macrophages: evidence for CB2 receptor participation
    K L McCoy
    Department of Microbiology and Immunology, Medical College of Virginia of Virginia Commonwealth University, Richmond, Virginia, USA
    J Pharmacol Exp Ther 289:1620-5. 1999
  4. ncbi request reprint The increasing importance of Acanthamoeba infections
    F Marciano-Cabral
    Department of Microbiology and Immunology, Medical College of Virginia of Virginia Commonwealth University, Richmond 23298 0678, USA
    J Eukaryot Microbiol 47:29-36. 2000
  5. pmc CB2 receptors in the brain: role in central immune function
    G A Cabral
    Department of Microbiology and Immunology, Virginia Commonwealth University, School of Medicine, Richmond, VA 23298 0678, USA
    Br J Pharmacol 153:240-51. 2008
  6. ncbi request reprint Cannabinoids inhibit LPS-inducible cytokine mRNA expression in rat microglial cells
    R A Puffenbarger
    Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond 23298 0678, USA
    Glia 29:58-69. 2000
  7. ncbi request reprint Cannabinoid receptors in microglia of the central nervous system: immune functional relevance
    G A Cabral
    Department of Microbiology and Immunology, Virginia Commonwealth University, School of Medicine, 1101 E Marshall Street, Richmond, VA 23298 0678, USA
    J Leukoc Biol 78:1192-7. 2005
  8. ncbi request reprint Differential expression of the CB2 cannabinoid receptor by rodent macrophages and macrophage-like cells in relation to cell activation
    S J Carlisle
    Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond 23298 0678, USA
    Int Immunopharmacol 2:69-82. 2002
  9. ncbi request reprint Cannabinoid-mediated inhibition of inducible nitric oxide production by rat microglial cells: evidence for CB1 receptor participation
    G A Cabral
    Department of Microbiology and Immunology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298 0678, USA
    Adv Exp Med Biol 493:207-14. 2001
  10. pmc Cannabinoids as therapeutic agents for ablating neuroinflammatory disease
    G A Cabral
    Department of Microbiology and Immunology, Virginia Commonwealth University, School of Medicine, 1101 E Marshall Street, Richmond, Virginia 23298 0678 USA
    Endocr Metab Immune Disord Drug Targets 8:159-72. 2008

Collaborators

  • F Marciano-Cabral
  • K L McCoy
  • P H Reggio
  • M E Abood
  • B Rocha-Azevedo
  • S J Carlisle
  • R A Puffenbarger
  • Q Tao
  • M Jamerson
  • F C Silva-Filho
  • D A Pettit
  • A Staab
  • C Ludwick
  • A C Boothe
  • D P Hurst
  • K W Nowell
  • K Bachtel
  • S D McAllister
  • M C Ekman
  • J Andreassi
  • J M Olson
  • R F Spencer
  • M P Harrison

Detail Information

Publications12

  1. ncbi request reprint Drugs and immunity: cannabinoids and their role in decreased resistance to infectious disease
    G A Cabral
    Department of Microbiology and Immunology, Medical College of Virginia Virginia Commonwealth University, Richmond 23298 0678, USA
    J Neuroimmunol 83:116-23. 1998
    ..However, cumulative reports indicating that THC alters resistance to infection in vitro and in a variety of experimental animals support the hypothesis that a similar effect occurs in humans...
  2. ncbi request reprint Immunohistochemical localization of the neural cannabinoid receptor in rat brain
    D A Pettit
    Department of Pharmacology Toxicology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298 0678, USA
    J Neurosci Res 51:391-402. 1998
    ..These data indicate that the anti-CB1 antibody is a sensitive probe for the unequivocal histological discrimination of CB1 protein expression...
  3. ncbi request reprint Cannabinoid inhibition of the processing of intact lysozyme by macrophages: evidence for CB2 receptor participation
    K L McCoy
    Department of Microbiology and Immunology, Medical College of Virginia of Virginia Commonwealth University, Richmond, Virginia, USA
    J Pharmacol Exp Ther 289:1620-5. 1999
    ..These findings suggest that the CB2 receptor may be involved in CB inhibition of antigen processing by macrophages in this system...
  4. ncbi request reprint The increasing importance of Acanthamoeba infections
    F Marciano-Cabral
    Department of Microbiology and Immunology, Medical College of Virginia of Virginia Commonwealth University, Richmond 23298 0678, USA
    J Eukaryot Microbiol 47:29-36. 2000
    ..castellanii in vitro. These results implicate macrophages as playing an effector role against Acanthamoeba and suggest immune modulation as a potential alternative therapeutic mode of treatment for these infections...
  5. pmc CB2 receptors in the brain: role in central immune function
    G A Cabral
    Department of Microbiology and Immunology, Virginia Commonwealth University, School of Medicine, Richmond, VA 23298 0678, USA
    Br J Pharmacol 153:240-51. 2008
    ..Furthermore, the collective results suggest that the CB2R plays a critical immune functional role in the CNS...
  6. ncbi request reprint Cannabinoids inhibit LPS-inducible cytokine mRNA expression in rat microglial cells
    R A Puffenbarger
    Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond 23298 0678, USA
    Glia 29:58-69. 2000
    ....
  7. ncbi request reprint Cannabinoid receptors in microglia of the central nervous system: immune functional relevance
    G A Cabral
    Department of Microbiology and Immunology, Virginia Commonwealth University, School of Medicine, 1101 E Marshall Street, Richmond, VA 23298 0678, USA
    J Leukoc Biol 78:1192-7. 2005
    ....
  8. ncbi request reprint Differential expression of the CB2 cannabinoid receptor by rodent macrophages and macrophage-like cells in relation to cell activation
    S J Carlisle
    Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond 23298 0678, USA
    Int Immunopharmacol 2:69-82. 2002
    ..Furthermore, since inflammatory and primed macrophages express the highest levels of CB2, the functional activities of macrophages when in these respective states of activation may be the most sensitive to the action of cannabinoids...
  9. ncbi request reprint Cannabinoid-mediated inhibition of inducible nitric oxide production by rat microglial cells: evidence for CB1 receptor participation
    G A Cabral
    Department of Microbiology and Immunology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298 0678, USA
    Adv Exp Med Biol 493:207-14. 2001
    ..Collectively, these results indicate that the cannabinoid analog CP55940 selectively inhibits inducible NO production by microglial cells and that this inhibition is effected, at least in part, through the CB1 receptor...
  10. pmc Cannabinoids as therapeutic agents for ablating neuroinflammatory disease
    G A Cabral
    Department of Microbiology and Immunology, Virginia Commonwealth University, School of Medicine, 1101 E Marshall Street, Richmond, Virginia 23298 0678 USA
    Endocr Metab Immune Disord Drug Targets 8:159-72. 2008
    ....
  11. ncbi request reprint The interaction between the amoeba Balamuthia mandrillaris and extracellular matrix glycoproteins in vitro
    B Rocha-Azevedo
    Programa de Bioengenharia e Biotecnologia Animal, Instituto de Biofisica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
    Parasitology 134:51-8. 2007
    ..Dependence of divalent cations on amoeba binding was demonstrated for laminin-amoeba interaction. Collectively, the results indicate that B. mandrillaris recognizes specific glycoproteins of the mammalian extracellular matrix...
  12. ncbi request reprint Role of a conserved lysine residue in the peripheral cannabinoid receptor (CB2): evidence for subtype specificity
    Q Tao
    Department of Pharmacology, Virginia Commonwealth University, Richmond 23298 0524, USA
    Mol Pharmacol 55:605-13. 1999
    ..In summary, we identified amino acid residues in the CB2 receptor that could lead to subtype specificity...