Darlene H Brunzell

Summary

Affiliation: Virginia Commonwealth University
Country: USA

Publications

  1. pmc Preclinical evidence that activation of mesolimbic alpha 6 subunit containing nicotinic acetylcholine receptors supports nicotine addiction phenotype
    Darlene H Brunzell
    Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA
    Nicotine Tob Res 14:1258-69. 2012
  2. pmc Alpha7 nicotinic acetylcholine receptors modulate motivation to self-administer nicotine: implications for smoking and schizophrenia
    Darlene H Brunzell
    Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA 23298, USA
    Neuropsychopharmacology 37:1134-43. 2012
  3. pmc Alpha-conotoxin MII-sensitive nicotinic acetylcholine receptors in the nucleus accumbens shell regulate progressive ratio responding maintained by nicotine
    Darlene H Brunzell
    Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA 23298, USA
    Neuropsychopharmacology 35:665-73. 2010
  4. pmc Low dose nicotine and antagonism of β2 subunit containing nicotinic acetylcholine receptors have similar effects on affective behavior in mice
    Shawn M Anderson
    Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
    PLoS ONE 7:e48665. 2012
  5. pmc ACSL6 is associated with the number of cigarettes smoked and its expression is altered by chronic nicotine exposure
    Jingchun Chen
    Department of Psychiatry and Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America
    PLoS ONE 6:e28790. 2011

Research Grants

Collaborators

Detail Information

Publications5

  1. pmc Preclinical evidence that activation of mesolimbic alpha 6 subunit containing nicotinic acetylcholine receptors supports nicotine addiction phenotype
    Darlene H Brunzell
    Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA
    Nicotine Tob Res 14:1258-69. 2012
    ....
  2. pmc Alpha7 nicotinic acetylcholine receptors modulate motivation to self-administer nicotine: implications for smoking and schizophrenia
    Darlene H Brunzell
    Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA 23298, USA
    Neuropsychopharmacology 37:1134-43. 2012
    ..These data identify reduction of α7 nAChR function as a potential mechanism for elevated tobacco use in schizophrenia and also identify activation of α7 nAChRs as a potential strategy for tobacco cessation therapy...
  3. pmc Alpha-conotoxin MII-sensitive nicotinic acetylcholine receptors in the nucleus accumbens shell regulate progressive ratio responding maintained by nicotine
    Darlene H Brunzell
    Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA 23298, USA
    Neuropsychopharmacology 35:665-73. 2010
    ..These data suggest that alpha6beta2(*)nAChRs in the NAc shell regulate motivational aspects of nicotine reinforcement but not nicotine-associated locomotor activation...
  4. pmc Low dose nicotine and antagonism of β2 subunit containing nicotinic acetylcholine receptors have similar effects on affective behavior in mice
    Shawn M Anderson
    Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
    PLoS ONE 7:e48665. 2012
    ..These data further identify β2*nAChR antagonism as a potential therapeutic strategy for relief of negative affect and anxiety...
  5. pmc ACSL6 is associated with the number of cigarettes smoked and its expression is altered by chronic nicotine exposure
    Jingchun Chen
    Department of Psychiatry and Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America
    PLoS ONE 6:e28790. 2011
    ..The independent associations of this locus with schizophrenia and with numCIG in non-schizophrenic subjects suggest that this locus may be a common liability to both conditions...

Research Grants2