Paola M Barral

Summary

Affiliation: Virginia Commonwealth University
Country: USA

Publications

  1. pmc Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: key regulators of innate immunity
    Paola M Barral
    Department of Human and Molecular Genetics, Virginia Commonwealth University, School of Medicine, Richmond, VA, USA
    Pharmacol Ther 124:219-34. 2009
  2. pmc Role of excitatory amino acid transporter-2 (EAAT2) and glutamate in neurodegeneration: opportunities for developing novel therapeutics
    Keetae Kim
    Department of Human and Molecular Genetics, Virginia Commonwealth University, School of Medicine, Richmond, Virginia 23298, USA
    J Cell Physiol 226:2484-93. 2011
  3. pmc RIG-I is cleaved during picornavirus infection
    Paola M Barral
    Department of Human and Molecular Genetics, Virginia Commonwealth University School of Medicine, 1101 East Marshall Street, Sanger Hall Building, Room 11 015, Richmond, VA 23298 0033, USA
    Virology 391:171-6. 2009

Collaborators

  • Keetae Kim
  • Swadesh K Das
  • Seok Geun Lee
  • Paul Diaz
  • Devanand Sarkar
  • Timothy P Kegelman
  • Santanu Dasgupta
  • Rupesh Dash
  • Michael Hedvat
  • Paul B Fisher
  • Zhao Zhong Su
  • Maurizio Pellecchia
  • John L Stebbins
  • John C Reed

Detail Information

Publications3

  1. pmc Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: key regulators of innate immunity
    Paola M Barral
    Department of Human and Molecular Genetics, Virginia Commonwealth University, School of Medicine, Richmond, VA, USA
    Pharmacol Ther 124:219-34. 2009
    ..We also consider the function of these cytoplasmic sensors in apoptosis, development and differentiation, and diabetes...
  2. pmc Role of excitatory amino acid transporter-2 (EAAT2) and glutamate in neurodegeneration: opportunities for developing novel therapeutics
    Keetae Kim
    Department of Human and Molecular Genetics, Virginia Commonwealth University, School of Medicine, Richmond, Virginia 23298, USA
    J Cell Physiol 226:2484-93. 2011
    ....
  3. pmc RIG-I is cleaved during picornavirus infection
    Paola M Barral
    Department of Human and Molecular Genetics, Virginia Commonwealth University School of Medicine, 1101 East Marshall Street, Sanger Hall Building, Room 11 015, Richmond, VA 23298 0033, USA
    Virology 391:171-6. 2009
    ..Rather, the viral proteinase 3C(pro) cleaves RIG-I, both in vitro and in cells. Cleavage of RIG-I during picornavirus infection may constitute another mechanism for attenuating the innate response to viral infection...