M D Aceto

Summary

Affiliation: Virginia Commonwealth University
Country: USA

Publications

  1. ncbi request reprint Stereoselective mu- and delta-opioid receptor-related antinociception and binding with (+)-thebaine
    M D Aceto
    Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth Univeristy, Richmond 23298 0613, USA
    Eur J Pharmacol 365:143-7. 1999
  2. ncbi request reprint Dihydroetorphine: physical dependence and stereotypy after continuous infusion in the rat
    M D Aceto
    Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, VA 23298 0613, USA
    Eur J Pharmacol 387:31-7. 2000
  3. ncbi request reprint Spontaneous and precipitated withdrawal with a synthetic cannabinoid, WIN 55212-2
    M D Aceto
    Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond 23298 0613, USA
    Eur J Pharmacol 416:75-81. 2001
  4. ncbi request reprint Antipodal alpha-N-(methyl through decyl)-N-normetazocines (5,9 alpha-dimethyl-2'-hydroxy-6,7-benzomorphans): in vitro and in vivo properties
    E L May
    Department of Pharmacology and Toxicology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298 0613
    J Med Chem 37:3408-18. 1994
  5. ncbi request reprint Etorphines: mu-opioid receptor-selective antinociception and low physical dependence capacity
    M D Aceto
    Department of Pharmacology and Toxicology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298 0613, USA
    Eur J Pharmacol 338:215-23. 1997
  6. ncbi request reprint Antinociceptive and pharmacological effects of metanicotine, a selective nicotinic agonist
    M I Damaj
    Department of Pharmacology and Toxicology, Medical College of Virginia of Virginia Commonwealth University, Richmond, Virginia, USA
    J Pharmacol Exp Ther 291:390-8. 1999
  7. ncbi request reprint Cocaine-induced rausch: overt behaviour and plasma concentrations in rhesus monkeys
    J J Saady
    Department of Pathology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298 0613
    Eur J Drug Metab Pharmacokinet 19:41-6. 1994

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Stereoselective mu- and delta-opioid receptor-related antinociception and binding with (+)-thebaine
    M D Aceto
    Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth Univeristy, Richmond 23298 0613, USA
    Eur J Pharmacol 365:143-7. 1999
    ..75+/-0.01 microM). Opioid-induced antinociception associated with unnatural thebaine raises the possibility of additional mu- and delta-opioid receptor sites...
  2. ncbi request reprint Dihydroetorphine: physical dependence and stereotypy after continuous infusion in the rat
    M D Aceto
    Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, VA 23298 0613, USA
    Eur J Pharmacol 387:31-7. 2000
    ..Although many reported molecular events and dependence studies suggest otherwise, dihydroetorphine's propensity to produce physical dependence, an important determinant of opioid abuse, is real...
  3. ncbi request reprint Spontaneous and precipitated withdrawal with a synthetic cannabinoid, WIN 55212-2
    M D Aceto
    Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond 23298 0613, USA
    Eur J Pharmacol 416:75-81. 2001
    ..Anandamide, which showed little, if any, physical dependence potential, behaved atypically. Possible implications regarding pharmacotherapeutic and human abuse issues are discussed...
  4. ncbi request reprint Antipodal alpha-N-(methyl through decyl)-N-normetazocines (5,9 alpha-dimethyl-2'-hydroxy-6,7-benzomorphans): in vitro and in vivo properties
    E L May
    Department of Pharmacology and Toxicology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298 0613
    J Med Chem 37:3408-18. 1994
    ..The (+)-butyl through (+)-octyl homologs were essentially equipotent with, or more potent than, (+)-pentazocine at the sigma receptor. Only the (+)-H and (+)-methyl homologs had high affinity (< 0.05 microM) at PCP binding sites...
  5. ncbi request reprint Etorphines: mu-opioid receptor-selective antinociception and low physical dependence capacity
    M D Aceto
    Department of Pharmacology and Toxicology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298 0613, USA
    Eur J Pharmacol 338:215-23. 1997
    ..The results suggest that these atypical opioids may be useful in the clinical treatment of pain and opiate drug abuse...
  6. ncbi request reprint Antinociceptive and pharmacological effects of metanicotine, a selective nicotinic agonist
    M I Damaj
    Department of Pharmacology and Toxicology, Medical College of Virginia of Virginia Commonwealth University, Richmond, Virginia, USA
    J Pharmacol Exp Ther 291:390-8. 1999
    ..Thus, metanicotine and related nicotinic agonists may have great potential for development as a new class of analgesics...
  7. ncbi request reprint Cocaine-induced rausch: overt behaviour and plasma concentrations in rhesus monkeys
    J J Saady
    Department of Pathology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298 0613
    Eur J Drug Metab Pharmacokinet 19:41-6. 1994
    ..The results showed dose-response relationships for both plasma concentrations of cocaine and for the total number of overt behavioural signs. The plasma concentrations were in the range reported for human cocaine abusers...