H M Horton
Affiliation: Vical Incorporated
- A gene therapy for cancer using intramuscular injection of plasmid DNA encoding interferon alphaH M Horton
Vical, Inc, 9373 Towne Centre Drive, Suite 100, San Diego, CA 92121, USA
Proc Natl Acad Sci U S A 96:1553-8. 1999..These studies demonstrate that primary and metastatic tumors can be treated systemically by i.m. injection of a plasmid encoding a cytokine gene...
- Antitumor effects of interferon-omega: in vivo therapy of human tumor xenografts in nude miceH M Horton
Vical, Inc, San Diego, California 92121, USA
Cancer Res 59:4064-8. 1999..009). These results demonstrate for the first time that IFN-omega can have in vivo antitumor effects in several models of human cancer...
- IL-2 plasmid therapy of murine ovarian carcinoma inhibits the growth of tumor ascites and alters its cytokine profileH M Horton
Vical, Inc, San Diego, CA 92121, USA
J Immunol 163:6378-85. 1999..p. treatment of ovarian tumors with IL-2 pDNA:DMRIE/DOPE can lead to an increase in local IL-2 levels, a change in the cytokine profile of the tumor ascites, and a significant antitumor effect...