H M Horton

Summary

Affiliation: Vical Incorporated
Country: USA

Publications

  1. pmc A gene therapy for cancer using intramuscular injection of plasmid DNA encoding interferon alpha
    H M Horton
    Vical, Inc, 9373 Towne Centre Drive, Suite 100, San Diego, CA 92121, USA
    Proc Natl Acad Sci U S A 96:1553-8. 1999
  2. ncbi Antitumor effects of interferon-omega: in vivo therapy of human tumor xenografts in nude mice
    H M Horton
    Vical, Inc, San Diego, California 92121, USA
    Cancer Res 59:4064-8. 1999
  3. ncbi IL-2 plasmid therapy of murine ovarian carcinoma inhibits the growth of tumor ascites and alters its cytokine profile
    H M Horton
    Vical, Inc, San Diego, CA 92121, USA
    J Immunol 163:6378-85. 1999

Detail Information

Publications3

  1. pmc A gene therapy for cancer using intramuscular injection of plasmid DNA encoding interferon alpha
    H M Horton
    Vical, Inc, 9373 Towne Centre Drive, Suite 100, San Diego, CA 92121, USA
    Proc Natl Acad Sci U S A 96:1553-8. 1999
    ..These studies demonstrate that primary and metastatic tumors can be treated systemically by i.m. injection of a plasmid encoding a cytokine gene...
  2. ncbi Antitumor effects of interferon-omega: in vivo therapy of human tumor xenografts in nude mice
    H M Horton
    Vical, Inc, San Diego, California 92121, USA
    Cancer Res 59:4064-8. 1999
    ..009). These results demonstrate for the first time that IFN-omega can have in vivo antitumor effects in several models of human cancer...
  3. ncbi IL-2 plasmid therapy of murine ovarian carcinoma inhibits the growth of tumor ascites and alters its cytokine profile
    H M Horton
    Vical, Inc, San Diego, CA 92121, USA
    J Immunol 163:6378-85. 1999
    ..p. treatment of ovarian tumors with IL-2 pDNA:DMRIE/DOPE can lead to an increase in local IL-2 levels, a change in the cytokine profile of the tumor ascites, and a significant antitumor effect...