G W Bemis
Affiliation: Vertex Pharmaceuticals
- The properties of known drugs. 1. Molecular frameworksG W Bemis
Vertex Pharmaceuticals, Cambridge, Massachusetts 02139 4242, USA
J Med Chem 39:2887-93. 1996..We discuss the possible interpretations of these findings and the way they may be used to guide future drug discovery research...
- Designing libraries with CNS activity- Ajay
Vertex Pharmaceuticals Inc, 130 Waverly Street, Cambridge, Massachusetts 02139, USA
J Med Chem 42:4942-51. 1999..This was done by building and analyzing a large database of a million compounds constructed from frameworks and side chains frequently found in drug molecules...
- Kinase chemogenomics: targeting the human kinome for target validation and drug discoveryE ter Haar
Vertex Pharmaceuticals, Inc, 130 Waverly Street, Cambridge, Massachusetts 02139, USA
Mini Rev Med Chem 4:235-53. 2004..Specific examples from the SAPK-family will be discussed...