Genomes and Genes
Cynthia K Damer
Affiliation: Vassar College
- Copine A, a calcium-dependent membrane-binding protein, transiently localizes to the plasma membrane and intracellular vacuoles in DictyosteliumCynthia K Damer
Biology Department, Vassar College, Poughkeepsie, NY 12604, USA
BMC Cell Biol 6:46. 2005..The "A domain" is similar in sequence to the von Willebrand A (VWA) domain found in integrins. The presence of C2 domains suggests that copines may be involved in cell signaling and/or membrane trafficking pathways...
- Copine A is required for cytokinesis, contractile vacuole function, and development in DictyosteliumCynthia K Damer
Biology Department, Vassar College, Box 566, 124 Raymond Ave, Poughkeepsie, NY 12604, USA
Eukaryot Cell 6:430-42. 2007..All of the copine genes except cpnF showed an upregulation of mRNA expression at one or two developmental transitions, suggesting that copines may be important regulators of Dictyostelium development...
- Copine A is expressed in prestalk cells and regulates slug phototaxis and thermotaxis in developing DictyosteliumKerry A Flegel
Biology Department, Central Michigan University, Mount Pleasant, Michigan 48859, USA
Dev Growth Differ 53:948-59. 2011..Our results suggest that CpnA plays a role in the regulation of the signaling pathways, including ammonia signaling, necessary for sensing and/or orienting toward light and heat in the prestalk cells of the Dictyostelium slug...