Siyuan Zheng

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. pmc Integrative network analysis identifies key genes and pathways in the progression of hepatitis C virus induced hepatocellular carcinoma
    Siyuan Zheng
    Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    BMC Med Genomics 4:62. 2011
  2. pmc Role of insulin-like growth factor-1 signaling pathway in cisplatin-resistant lung cancer cells
    Yunguang Sun
    Department of Radiation Oncology, Vanderbilt University Medical Center, Nashville, TN 37232 5671, USA
    Int J Radiat Oncol Biol Phys 82:e563-72. 2012
  3. pmc DNA methylation profiling distinguishes three clusters of breast cancer cell lines
    Siyuan Zheng
    Department of Biomedical Informatics, Vanderbilt University School of Medicine, 2525 West End Avenue, Suite 600, Nashville, TN 37203, USA
    Chem Biodivers 9:848-56. 2012
  4. pmc Epithelial cell organization suppresses Myc function by attenuating Myc expression
    David R Simpson
    Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Cancer Res 71:3822-30. 2011
  5. pmc GenRev: exploring functional relevance of genes in molecular networks
    Siyuan Zheng
    Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Genomics 99:183-8. 2012
  6. pmc Connectivity map analysis of nonsense-mediated decay-positive BMPR2-related hereditary pulmonary arterial hypertension provides insights into disease penetrance
    Charles Flynn
    Departments of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Am J Respir Cell Mol Biol 47:20-7. 2012

Collaborators

Detail Information

Publications6

  1. pmc Integrative network analysis identifies key genes and pathways in the progression of hepatitis C virus induced hepatocellular carcinoma
    Siyuan Zheng
    Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    BMC Med Genomics 4:62. 2011
    ..Although HCV-associated HCC shares many pathological characteristics with other types of HCC, its molecular mechanisms of progression remain elusive...
  2. pmc Role of insulin-like growth factor-1 signaling pathway in cisplatin-resistant lung cancer cells
    Yunguang Sun
    Department of Radiation Oncology, Vanderbilt University Medical Center, Nashville, TN 37232 5671, USA
    Int J Radiat Oncol Biol Phys 82:e563-72. 2012
    ..We aimed to identify some of the molecular mechanisms that underlie cisplatin resistance using microarray expression analysis...
  3. pmc DNA methylation profiling distinguishes three clusters of breast cancer cell lines
    Siyuan Zheng
    Department of Biomedical Informatics, Vanderbilt University School of Medicine, 2525 West End Avenue, Suite 600, Nashville, TN 37203, USA
    Chem Biodivers 9:848-56. 2012
    ..Although these results are preliminary, this study suggests that methylation profiling might be promising in disease subtype classification and the development of therapeutic strategies...
  4. pmc Epithelial cell organization suppresses Myc function by attenuating Myc expression
    David R Simpson
    Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Cancer Res 71:3822-30. 2011
    ..These observations reveal that organization does not alter the inherent response of epithelial cells to Myc and suggest that other tumor suppression mechanisms, apart from structure, antagonize Myc in the development of solid tumors...
  5. pmc GenRev: exploring functional relevance of genes in molecular networks
    Siyuan Zheng
    Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Genomics 99:183-8. 2012
    ..GenRev is particularly designed for general use so that users have the flexibility to choose a reference network and define the score of genes. GenRev is freely available at http://bioinfo.mc.vanderbilt.edu/GenRev.html...
  6. pmc Connectivity map analysis of nonsense-mediated decay-positive BMPR2-related hereditary pulmonary arterial hypertension provides insights into disease penetrance
    Charles Flynn
    Departments of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Am J Respir Cell Mol Biol 47:20-7. 2012
    ..These results provide the first molecular insights into NMD+ BMPR2 related HPAH penetrance and highlight the potential utility of cMap analyses in pulmonary research...