Xianglan Zhang

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. pmc Associations of Tai Chi, walking, and jogging with mortality in Chinese men
    Na Wang
    Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, 2525 West End Avenue, Nashville, TN 37203, USA
    Am J Epidemiol 178:791-6. 2013
  2. pmc Visceral adiposity and risk of coronary heart disease in relatively lean Chinese adults
    Xianglan Zhang
    Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA Electronic address
    Int J Cardiol 168:2141-5. 2013
  3. pmc Urinary isoflavonoids and risk of coronary heart disease
    Xianglan Zhang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Int J Epidemiol 41:1367-75. 2012
  4. pmc Pregnancy, childrearing, and risk of stroke in Chinese women
    Xianglan Zhang
    Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt University Medical Center, Sixth Floor, Suite 600, 2525 West End Avenue, Nashville, TN 37203 1738, USA
    Stroke 40:2680-4. 2009
  5. pmc Cruciferous vegetable consumption is associated with a reduced risk of total and cardiovascular disease mortality
    Xianglan Zhang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA
    Am J Clin Nutr 94:240-6. 2011
  6. pmc Resting heart rate and risk of type 2 diabetes in women
    Xianglan Zhang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA
    Int J Epidemiol 39:900-6. 2010
  7. pmc General and abdominal adiposity and risk of stroke in Chinese women
    Xianglan Zhang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tenn 37203 1738, USA
    Stroke 40:1098-104. 2009
  8. pmc Body mass index at various ages and mortality in Chinese women: impact of potential methodological biases
    X Zhang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Int J Obes (Lond) 32:1130-6. 2008
  9. ncbi request reprint Abdominal adiposity and mortality in Chinese women
    Xianglan Zhang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37232 8300, USA
    Arch Intern Med 167:886-92. 2007
  10. pmc Associations of adult height and its components with mortality: a report from cohort studies of 135,000 Chinese women and men
    Na Wang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Int J Epidemiol 40:1715-26. 2011

Research Grants

Detail Information

Publications36

  1. pmc Associations of Tai Chi, walking, and jogging with mortality in Chinese men
    Na Wang
    Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, 2525 West End Avenue, Nashville, TN 37203, USA
    Am J Epidemiol 178:791-6. 2013
    ..90) for jogging. Similar inverse associations were also found for cancer and cardiovascular mortality. The present study provides the first evidence that, like walking and jogging, practicing Tai Chi is associated with reduced mortality. ..
  2. pmc Visceral adiposity and risk of coronary heart disease in relatively lean Chinese adults
    Xianglan Zhang
    Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA Electronic address
    Int J Cardiol 168:2141-5. 2013
    ..These markers may be particularly useful to Asian populations who generally have a low body weight but are prone to visceral adiposity...
  3. pmc Urinary isoflavonoids and risk of coronary heart disease
    Xianglan Zhang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Int J Epidemiol 41:1367-75. 2012
    ..No previous study has used biomarkers of soy intake in assessing the relationship between soy consumption and CHD. Biomarkers that reflect both intake and metabolism may be more informative than self-reports of dietary intake...
  4. pmc Pregnancy, childrearing, and risk of stroke in Chinese women
    Xianglan Zhang
    Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt University Medical Center, Sixth Floor, Suite 600, 2525 West End Avenue, Nashville, TN 37203 1738, USA
    Stroke 40:2680-4. 2009
    ..Although it has been suggested that high gravidity and parity increase the risk for coronary heart disease, their associations with stroke are unclear...
  5. pmc Cruciferous vegetable consumption is associated with a reduced risk of total and cardiovascular disease mortality
    Xianglan Zhang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA
    Am J Clin Nutr 94:240-6. 2011
    ..Asian populations habitually consume a large amount of cruciferous vegetables and other plant-based foods. Few epidemiologic investigations have evaluated the potential health effects of these foods in Asian populations...
  6. pmc Resting heart rate and risk of type 2 diabetes in women
    Xianglan Zhang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA
    Int J Epidemiol 39:900-6. 2010
    ..Resting heart rate has been shown to predict risk of cardiovascular disease; its association with diabetes remains unclear, particularly in non-Western populations...
  7. pmc General and abdominal adiposity and risk of stroke in Chinese women
    Xianglan Zhang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tenn 37203 1738, USA
    Stroke 40:1098-104. 2009
    ..Although both general and abdominal adiposity are well-established risk factors for coronary heart disease, their associations with stroke are less well characterized, particularly in generally lean Asian populations...
  8. pmc Body mass index at various ages and mortality in Chinese women: impact of potential methodological biases
    X Zhang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Int J Obes (Lond) 32:1130-6. 2008
    ..Inadequate control for potential methodological biases has been suggested as an explanation for the conflicting findings concerning the relationship between body mass index (BMI) and mortality...
  9. ncbi request reprint Abdominal adiposity and mortality in Chinese women
    Xianglan Zhang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37232 8300, USA
    Arch Intern Med 167:886-92. 2007
    ..Increased abdominal adiposity has been linked to an increase in mortality in populations where many are overweight or obese; it is unclear whether the same is true in relatively lean populations...
  10. pmc Associations of adult height and its components with mortality: a report from cohort studies of 135,000 Chinese women and men
    Na Wang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Int J Epidemiol 40:1715-26. 2011
    ..Little is known about components of adult height in relation to mortality, particularly in developing countries...
  11. pmc Prospective cohort study of soy food intake and colorectal cancer risk in women
    Gong Yang
    Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Am J Clin Nutr 89:577-83. 2009
    ..Data from epidemiologic studies linking usual soy food intake with colorectal cancer are limited and inconsistent...
  12. pmc Fish intake and risks of total and cause-specific mortality in 2 population-based cohort studies of 134,296 men and women
    Yumie Takata
    Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, 2525West End, Suite 600 Institute for Medicine and Public Health, Nashville, TN 37203, USA
    Am J Epidemiol 178:46-57. 2013
    ..Overall, our findings support the postulated health benefits of fish consumption. ..
  13. pmc Prediagnosis soy food consumption and lung cancer survival in women
    Gong Yang
    Vanderbilt University Medical Center, Nashville, TN 37203 1738, USA
    J Clin Oncol 31:1548-53. 2013
    ..The effect size for aggressive lung cancers was larger than that observed for other types of lung cancer. Therefore, we hypothesized that soy consumption may favorably affect the overall survival of patients with lung cancer...
  14. pmc Soy food intake and risk of lung cancer: evidence from the Shanghai Women's Health Study and a meta-analysis
    Gong Yang
    Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, 2525 West End Avenue, Suite 600, Nashville, TN 37203 1738, USA
    Am J Epidemiol 176:846-55. 2012
    ..This study suggests that soy food consumption may reduce lung cancer risk in nonsmoking women, particularly for aggressive tumors, and its effect may be modified by endogenous estrogens...
  15. pmc Red meat and poultry intakes and risk of total and cause-specific mortality: results from cohort studies of Chinese adults in Shanghai
    Yumie Takata
    Vanderbilt Epidemiology Center, Vanderbilt University, Nashville, Tennessee, United States of America
    PLoS ONE 8:e56963. 2013
    ..Further investigations are needed to elucidate the sex-specific associations between red meat intake and mortality...
  16. pmc Green tea consumption and colorectal cancer risk: a report from the Shanghai Men's Health Study
    Gong Yang
    Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, 2525 West End Avenue, Suite 600, IMPH, Nashville, TN 37203, USA
    Carcinogenesis 32:1684-8. 2011
    ..88, 95% CI: 0.78-0.99). No significant association was found among smokers (HR = 0.94, 95% CI: 0.66-1.34). This study suggests that regular consumption of green tea may reduce colorectal cancer risk among non-smokers...
  17. pmc Relation of blood pressure components and categories and all-cause, stroke and coronary heart disease mortality in urban Chinese women: a population-based prospective study
    Tsogzolmaa Dorjgochoo
    Department of Medicine, Vanderbilt Epidemiology Center, School of Medicine, and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA
    J Hypertens 27:468-75. 2009
    ..To determine whether various levels of blood pressure (BP), particularly normal and high normal BP or prehypertension, predict cardiovascular mortality among urban Chinese women...
  18. ncbi request reprint Longitudinal study of soy food intake and blood pressure among middle-aged and elderly Chinese women
    Gong Yang
    Vanderbilt Center for Health Services Research, Department of Medicine, Vanderbilt School of Medicine, and Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA
    Am J Clin Nutr 81:1012-7. 2005
    ..Several small-scale clinical trials have suggested a potential beneficial effect of short-term soy consumption on blood pressure (BP). Data are scanty on long-term effects of the usual intake of soy foods on BP in general populations...
  19. ncbi request reprint Prospective cohort study of soy food consumption and risk of bone fracture among postmenopausal women
    Xianglan Zhang
    Department of Medicine, Center for Health Services Research, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tenn 37232 8300, USA
    Arch Intern Med 165:1890-5. 2005
    ..Soy consumption has been shown to modulate bone turnover and increase bone mineral density in postmenopausal women. To our knowledge, no published studies have directly examined the association between soy consumption and risk of fracture...
  20. pmc Soy food intake and circulating levels of inflammatory markers in Chinese women
    Sheng Hui Wu
    Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37203 1738, USA
    J Acad Nutr Diet 112:996-1004, 1004.e1-4. 2012
    ..Soy and some of its constituents, such as isoflavones, have been shown to affect the inflammatory process in animal studies. The association between soy food intake and inflammatory markers has not been evaluated adequately in humans...
  21. pmc Age at menarche, the leg length to sitting height ratio, and risk of diabetes in middle-aged and elderly Chinese men and women
    Baqiyyah N Conway
    Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America
    PLoS ONE 7:e30625. 2012
    ..To evaluate the associations of age at menarche and the leg length-to-sitting-height ratio, markers of adolescent growth, with risk of diabetes in later life...
  22. pmc Adiposity and fat distribution in relation to inflammation and oxidative stress in a relatively lean population of Chinese women
    Sheng Hui Wu
    Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    Dis Markers 34:279-93. 2013
    ..This study evaluated associations of various anthropometric measures of adiposity with a panel of inflammatory and oxidative stress markers in a relatively lean population of Chinese women...
  23. ncbi request reprint Prospective cohort study of green tea consumption and colorectal cancer risk in women
    Gong Yang
    Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville TN 37232 2587, USA
    Cancer Epidemiol Biomarkers Prev 16:1219-23. 2007
    ..43; 95% confidence interval, 0.24-0.77). The inverse association with regular tea drinking was observed for both colon and rectal cancers. This study suggests that regular consumption of green tea may reduce CRC risk in women...
  24. doi request reprint Association between body-mass index and risk of death in more than 1 million Asians
    Wei Zheng
    Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN, USA
    N Engl J Med 364:719-29. 2011
    ..Most studies that have evaluated the association between the body-mass index (BMI) and the risks of death from any cause and from specific causes have been conducted in populations of European origin...
  25. pmc Hip circumference and the risk of type 2 diabetes in middle-aged and elderly men and women: the Shanghai women and Shanghai men's health studies
    Baqiyyah Conway
    Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, 37203 1738, USA
    Ann Epidemiol 21:358-66. 2011
    ..We sought to determine the association of hip circumference with risk of type 2 diabetes in a relatively lean population...
  26. pmc Correlates of high serum C-reactive protein levels in a socioeconomically disadvantaged population
    Xianglan Zhang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA
    Dis Markers 24:351-9. 2008
    ..Moreover, inflammatory response to obesity differed by race and sex, which may contribute to CVD disparities...
  27. ncbi request reprint Association of passive smoking by husbands with prevalence of stroke among Chinese women nonsmokers
    Xianglan Zhang
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA
    Am J Epidemiol 161:213-8. 2005
    ..The authors found that women nonsmokers who lived with husbands who smoked had an elevated prevalence of stroke, and prevalence increased with increasing intensity and duration of husbands' smoking...
  28. doi request reprint Fruit and vegetable intake and risk of CHD: results from prospective cohort studies of Chinese adults in Shanghai
    Danxia Yu
    Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Vanderbilt University School of Medicine, 2525 West End Avenue, Suite 600, IMPH, Nashville, TN 37203 1738, USA
    Br J Nutr 111:353-62. 2014
    ..For men, no significant association was found for fruit and vegetable intake when analysed either in combination or individually. The present findings suggest that a high consumption of fruits may reduce CHD risk in Chinese women. ..
  29. ncbi request reprint Soy food consumption is associated with lower risk of coronary heart disease in Chinese women
    Xianglan Zhang
    Department of Medicine, Center for Health Services Research, Vanderbilt University, Nashville, TN 37232, USA
    J Nutr 133:2874-8. 2003
    ..14; 95% CI, 0.04-0.48 for the highest vs. the lowest quartile of intake; P for trend = 0.001). This study provides, for the first time, direct evidence that soy food consumption may reduce the risk of CHD in women...
  30. ncbi request reprint Functional plasminogen activator inhibitor-1 gene variants and breast cancer survival
    Xianglan Zhang
    Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 8300, USA
    Clin Cancer Res 12:6037-42. 2006
    ..We evaluated the association between PAI-1 4G/5G polymorphism and breast cancer survival in a population-based cohort of breast cancer patients...
  31. ncbi request reprint Impacts of weight change on prehypertension in middle-aged and elderly women
    G Yang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, TN 37203, USA
    Int J Obes (Lond) 31:1818-25. 2007
    ..Data on impacts of long-term weight change on prehypertension are sparse...
  32. ncbi request reprint Body weight and weight change in relation to blood pressure in normotensive men
    G Yang
    Department of Medicine, Vanderbilt University School of Medicine, Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    J Hum Hypertens 21:45-52. 2007
    ....
  33. ncbi request reprint Anthropometric predictors of coronary heart disease in Chinese women
    X Zhang
    Department of Medicine, Center for Health Services Research, Vanderbilt University, Nashville, TN, USA
    Int J Obes Relat Metab Disord 28:734-40. 2004
    ..To evaluate the associations of body size and fat distribution with incidence of coronary heart disease (CHD) in Chinese women...
  34. ncbi request reprint PPARalpha agonist fenofibrate improves diabetic nephropathy in db/db mice
    C W Park
    Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Kidney Int 69:1511-7. 2006
    ..The activation of PPARalpha by fenofibrate in mesangial cells may partially contribute to its renal protection. Thus, fenofibrate may serve as a therapeutic agent for type II diabetes and diabetic nephropathy...
  35. ncbi request reprint Cardiomyopathy in transgenic mice with cardiac-specific overexpression of serum response factor
    X Zhang
    Department of Medicine, Beth Israel Deaconess Medical Center, and Division on Aging, Harvard Medical School, Boston, Massachusetts 02215, USA
    Am J Physiol Heart Circ Physiol 280:H1782-92. 2001
    ....
  36. ncbi request reprint Weight history and risk of endometrial cancer among Chinese women
    Wang Hong Xu
    Department of Epidemiology, Shanghai Cancer Institute, Cancer Institute of Shanghai Jiaotong University, 2200 25 Xie Tu Road, Shanghai 200032, P R China
    Int J Epidemiol 35:159-66. 2006
    ..We investigated whether women with greater early-age body size or with greater weight change during adulthood have an increased risk of endometrial cancer...

Research Grants1

  1. Phytoestrogen and Endogenous Estrogen Exposure and Risk of Stroke
    Xianglan Zhang; Fiscal Year: 2010
    ..Study results may contribute to the development of new strategies for the primary prevention of stroke. ..