Research Topics
Species | Xianglan ZhangSummaryAffiliation: Vanderbilt University Country: USA Publications
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Publications
Urinary isoflavonoids and risk of coronary heart diseaseXianglan Zhang
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
Int J Epidemiol 41:1367-75. 2012..No previous study has used biomarkers of soy intake in assessing the relationship between soy consumption and CHD. Biomarkers that reflect both intake and metabolism may be more informative than self-reports of dietary intake...
General and abdominal adiposity and risk of stroke in Chinese womenXianglan Zhang
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tenn 37203 1738, USA
Stroke 40:1098-104. 2009..Although both general and abdominal adiposity are well-established risk factors for coronary heart disease, their associations with stroke are less well characterized, particularly in generally lean Asian populations...
Body mass index at various ages and mortality in Chinese women: impact of potential methodological biasesX Zhang
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
Int J Obes (Lond) 32:1130-6. 2008..Inadequate control for potential methodological biases has been suggested as an explanation for the conflicting findings concerning the relationship between body mass index (BMI) and mortality...
Pregnancy, childrearing, and risk of stroke in Chinese womenXianglan Zhang
Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt University Medical Center, Sixth Floor, Suite 600, 2525 West End Avenue, Nashville, TN 37203 1738, USA
Stroke 40:2680-4. 2009..Although it has been suggested that high gravidity and parity increase the risk for coronary heart disease, their associations with stroke are unclear...
Abdominal adiposity and mortality in Chinese womenXianglan Zhang
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37232 8300, USA
Arch Intern Med 167:886-92. 2007..Increased abdominal adiposity has been linked to an increase in mortality in populations where many are overweight or obese; it is unclear whether the same is true in relatively lean populations...
Resting heart rate and risk of type 2 diabetes in womenXianglan Zhang
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA
Int J Epidemiol 39:900-6. 2010..Resting heart rate has been shown to predict risk of cardiovascular disease; its association with diabetes remains unclear, particularly in non-Western populations...
Cruciferous vegetable consumption is associated with a reduced risk of total and cardiovascular disease mortalityXianglan Zhang
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA
Am J Clin Nutr 94:240-6. 2011..Asian populations habitually consume a large amount of cruciferous vegetables and other plant-based foods. Few epidemiologic investigations have evaluated the potential health effects of these foods in Asian populations...
Prospective cohort study of soy food intake and colorectal cancer risk in womenGong Yang
Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
Am J Clin Nutr 89:577-83. 2009..Data from epidemiologic studies linking usual soy food intake with colorectal cancer are limited and inconsistent...
Associations of adult height and its components with mortality: a report from cohort studies of 135,000 Chinese women and menNa Wang
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
Int J Epidemiol 40:1715-26. 2011..Little is known about components of adult height in relation to mortality, particularly in developing countries...
Soy food intake and risk of lung cancer: evidence from the Shanghai Women's Health Study and a meta-analysisGong Yang
Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, 2525 West End Avenue, Suite 600, Nashville, TN 37203 1738, USA
Am J Epidemiol 176:846-55. 2012..This study suggests that soy food consumption may reduce lung cancer risk in nonsmoking women, particularly for aggressive tumors, and its effect may be modified by endogenous estrogens...
Green tea consumption and colorectal cancer risk: a report from the Shanghai Men's Health StudyGong Yang
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, 2525 West End Avenue, Suite 600, IMPH, Nashville, TN 37203, USA
Carcinogenesis 32:1684-8. 2011..88, 95% CI: 0.78-0.99). No significant association was found among smokers (HR = 0.94, 95% CI: 0.66-1.34). This study suggests that regular consumption of green tea may reduce colorectal cancer risk among non-smokers...
Relation of blood pressure components and categories and all-cause, stroke and coronary heart disease mortality in urban Chinese women: a population-based prospective studyTsogzolmaa Dorjgochoo
Department of Medicine, Vanderbilt Epidemiology Center, School of Medicine, and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA
J Hypertens 27:468-75. 2009..To determine whether various levels of blood pressure (BP), particularly normal and high normal BP or prehypertension, predict cardiovascular mortality among urban Chinese women...
Prospective cohort study of soy food consumption and risk of bone fracture among postmenopausal womenXianglan Zhang
Department of Medicine, Center for Health Services Research, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tenn. 37232-8300, USA
Arch Intern Med 165:1890-5. 2005..Similar results were also found for intake of isoflavones. CONCLUSION: Soy food consumption may reduce the risk of fracture in postmenopausal women, particularly among those in the early years following menopause...
Soy food intake and circulating levels of inflammatory markers in Chinese womenSheng Hui Wu
Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37203 1738, USA
J Acad Nutr Diet 112:996-1004, 1004.e1-4. 2012..Soy and some of its constituents, such as isoflavones, have been shown to affect the inflammatory process in animal studies. The association between soy food intake and inflammatory markers has not been evaluated adequately in humans...
Age at menarche, the leg length to sitting height ratio, and risk of diabetes in middle-aged and elderly Chinese men and womenBaqiyyah N Conway
Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America
PLoS ONE 7:e30625. 2012..To evaluate the associations of age at menarche and the leg length-to-sitting-height ratio, markers of adolescent growth, with risk of diabetes in later life...
Prediagnosis soy food consumption and lung cancer survival in womenGong Yang
Vanderbilt University School of Medicine, 2525 West End Ave, Suite 600, Nashville, TN 37203 1738
J Clin Oncol 31:1548-53. 2013..CONCLUSION This study suggests, to the best of our knowledge for the first time, that, among women with lung cancer, prediagnosis intake of soy food is associated with better overall survival...
Correlates of high serum C-reactive protein levels in a socioeconomically disadvantaged populationXianglan Zhang
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA
Dis Markers 24:351-9. 2008..Moreover, inflammatory response to obesity differed by race and sex, which may contribute to CVD disparities...
Prospective cohort study of green tea consumption and colorectal cancer risk in womenGong Yang
Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville TN 37232 2587, USA
Cancer Epidemiol Biomarkers Prev 16:1219-23. 2007..43; 95% confidence interval, 0.24-0.77). The inverse association with regular tea drinking was observed for both colon and rectal cancers. This study suggests that regular consumption of green tea may reduce CRC risk in women...
Association between body-mass index and risk of death in more than 1 million AsiansWei Zheng
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN, USA
N Engl J Med 364:719-29. 2011..Most studies that have evaluated the association between the body-mass index (BMI) and the risks of death from any cause and from specific causes have been conducted in populations of European origin...
Hip circumference and the risk of type 2 diabetes in middle-aged and elderly men and women: the Shanghai women and Shanghai men's health studiesBaqiyyah Conway
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, 37203 1738, USA
Ann Epidemiol 21:358-66. 2011..We sought to determine the association of hip circumference with risk of type 2 diabetes in a relatively lean population...
Longitudinal study of soy food intake and blood pressure among middle-aged and elderly Chinese womenGong Yang
Vanderbilt Center for Health Services Research, Department of Medicine, Vanderbilt School of Medicine, and Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA
Am J Clin Nutr 81:1012-7. 2005..0, -1.9 mm Hg) for systolic BP and -2.2 mm Hg (95% CI: -3.8, -0.6 mm Hg) for diastolic BP. CONCLUSION: Usual intake of soy foods was inversely associated with both systolic and diastolic BPs, particularly among elderly women...
Red meat and poultry intakes and risk of total and cause-specific mortality: results from cohort studies of Chinese adults in ShanghaiYumie Takata
Vanderbilt Epidemiology Center, Vanderbilt University, Nashville, Tennessee, United States of America
PLoS ONE 8:e56963. 2013..Further investigations are needed to elucidate the sex-specific associations between red meat intake and mortality...
Association of passive smoking by husbands with prevalence of stroke among Chinese women nonsmokersXianglan Zhang
Department of Medicine and Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA
Am J Epidemiol 161:213-8. 2005..The authors found that women nonsmokers who lived with husbands who smoked had an elevated prevalence of stroke, and prevalence increased with increasing intensity and duration of husbands' smoking...
Adiposity and fat distribution in relation to inflammation and oxidative stress in a relatively lean population of Chinese womenSheng Hui Wu
Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
Dis Markers 34:279-93. 2013..This study evaluated associations of various anthropometric measures of adiposity with a panel of inflammatory and oxidative stress markers in a relatively lean population of Chinese women...
Functional plasminogen activator inhibitor-1 gene variants and breast cancer survivalXianglan Zhang
Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 8300, USA
Clin Cancer Res 12:6037-42. 2006..We evaluated the association between PAI-1 4G/5G polymorphism and breast cancer survival in a population-based cohort of breast cancer patients...
Soy food consumption is associated with lower risk of coronary heart disease in Chinese womenXianglan Zhang
Department of Medicine, Center for Health Services Research, Vanderbilt University, Nashville, TN 37232, USA
J Nutr 133:2874-8. 2003..14; 95% CI, 0.04-0.48 for the highest vs. the lowest quartile of intake; P for trend = 0.001). This study provides, for the first time, direct evidence that soy food consumption may reduce the risk of CHD in women...
Impacts of weight change on prehypertension in middle-aged and elderly womenG Yang
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, TN 37203, USA
Int J Obes (Lond) 31:1818-25. 2007..Data on impacts of long-term weight change on prehypertension are sparse...
Body weight and weight change in relation to blood pressure in normotensive menG Yang
Department of Medicine, Vanderbilt University School of Medicine, Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN 37232, USA
J Hum Hypertens 21:45-52. 2007....
Anthropometric predictors of coronary heart disease in Chinese womenX Zhang
Department of Medicine, Center for Health Services Research, Vanderbilt University, Nashville, TN, USA
Int J Obes Relat Metab Disord 28:734-40. 2004..9 (1.0-8.4) for the elderly. CONCLUSIONS: WHR was positively associated with the risk of CHD in both younger and older women, while other anthropometrics, including BMI, were related to CHD risk primarily among younger women...
Cardiomyopathy in transgenic mice with cardiac-specific overexpression of serum response factorX Zhang
Department of Medicine, Beth Israel Deaconess Medical Center, and Division on Aging, Harvard Medical School, Boston, Massachusetts 02215, USA
Am J Physiol Heart Circ Physiol 280:H1782-92. 2001....
PPARalpha agonist fenofibrate improves diabetic nephropathy in db/db miceC W Park
Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, Tennessee, USA
Kidney Int 69:1511-7. 2006..The activation of PPARalpha by fenofibrate in mesangial cells may partially contribute to its renal protection. Thus, fenofibrate may serve as a therapeutic agent for type II diabetes and diabetic nephropathy...
Weight history and risk of endometrial cancer among Chinese womenWang Hong Xu
Department of Epidemiology, Shanghai Cancer Institute, Cancer Institute of Shanghai Jiaotong University, 2200/25 Xie Tu Road, Shanghai 200032, P.R. China
Int J Epidemiol 35:159-66. 2006..0 (95% CI 1.3-3.0) for women with BMI>or=25 kg/m2. CONCLUSIONS: Adult weight gain, particularly during the peri-menopausal period, plays a significant role in the development of endometrial cancer risk...
Research Grants
- Phytoestrogen and Endogenous Estrogen Exposure and Risk of StrokeXianglan Zhang; Fiscal Year: 2010..Study results may contribute to the development of new strategies for the primary prevention of stroke. ..
