Research Topics
Genomes and Genes | G YangSummaryAffiliation: Vanderbilt University Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Prediagnosis soy food consumption and lung cancer survival in womenGong Yang
Vanderbilt University School of Medicine, 2525 West End Ave, Suite 600, Nashville, TN 37203 1738
J Clin Oncol 31:1548-53. 2013..CONCLUSION This study suggests, to the best of our knowledge for the first time, that, among women with lung cancer, prediagnosis intake of soy food is associated with better overall survival...- Soy food intake and risk of lung cancer: evidence from the Shanghai Women's Health Study and a meta-analysisGong Yang
Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, 2525 West End Avenue, Suite 600, Nashville, TN 37203 1738, USA
Am J Epidemiol 176:846-55. 2012..This study suggests that soy food consumption may reduce lung cancer risk in nonsmoking women, particularly for aggressive tumors, and its effect may be modified by endogenous estrogens... - Patterns and correlates of physical activity: a cross-sectional study in urban Chinese womenAdriana L Jurj
Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37203, USA
BMC Public Health 7:213. 2007..The purpose of this study was to investigate the patterns and correlates of physical activity in middle-aged and elderly women from urban Shanghai... 
Prospective cohort study of green tea consumption and colorectal cancer risk in womenGong Yang
Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville TN 37232 2587, USA
Cancer Epidemiol Biomarkers Prev 16:1219-23. 2007..43; 95% confidence interval, 0.24-0.77). The inverse association with regular tea drinking was observed for both colon and rectal cancers. This study suggests that regular consumption of green tea may reduce CRC risk in women...- Impacts of weight change on prehypertension in middle-aged and elderly womenG Yang
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, TN 37203, USA
Int J Obes (Lond) 31:1818-25. 2007..Data on impacts of long-term weight change on prehypertension are sparse... - Genetic polymorphisms in glutathione-S-transferase genes (GSTM1, GSTT1, GSTP1) and survival after chemotherapy for invasive breast carcinomaGong Yang
Vanderbilt Center for Health Services Research, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232 8300, USA
Cancer 103:52-8. 2005.... - Prospective cohort study of soy food intake and colorectal cancer risk in womenGong Yang
Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
Am J Clin Nutr 89:577-83. 2009..Data from epidemiologic studies linking usual soy food intake with colorectal cancer are limited and inconsistent... - Isothiocyanate exposure, glutathione S-transferase polymorphisms, and colorectal cancer riskGong Yang
Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
Am J Clin Nutr 91:704-11. 2010..Glutathione S-transferases (GSTs) are involved in the metabolism and elimination of isothiocyanates; thus, genetic variations in these enzymes may affect in vivo bioavailability and the activity of isothiocyanates... - Body weight and weight change in relation to blood pressure in normotensive menG Yang
Department of Medicine, Vanderbilt University School of Medicine, Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN 37232, USA
J Hum Hypertens 21:45-52. 2007.... - Green tea consumption and colorectal cancer risk: a report from the Shanghai Men's Health StudyGong Yang
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, 2525 West End Avenue, Suite 600, IMPH, Nashville, TN 37203, USA
Carcinogenesis 32:1684-8. 2011..88, 95% CI: 0.78-0.99). No significant association was found among smokers (HR = 0.94, 95% CI: 0.66-1.34). This study suggests that regular consumption of green tea may reduce colorectal cancer risk among non-smokers... - Modifying effects of sulfotransferase 1A1 gene polymorphism on the association of breast cancer risk with body mass index or endogenous steroid hormonesGong Yang
Department of Medicine, Center for Health Services Research and Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN 37232 8300, USA
Breast Cancer Res Treat 94:63-70. 2005..No similar effect modification was found for premenopausal breast cancer, however. These data suggest that the SULT1A1 Arg213His polymorphism may modify the effect of endogenous sex hormone exposures on postmenopausal breast cancer risk... - Lifestyle determinants of C-reactive protein in middle-aged, urban Chinese menR Villegas
Vanderbilt University Medical Center, Nashville, TN 37206, USA
Nutr Metab Cardiovasc Dis 22:223-30. 2012..The aim of this study was to investigate associations between lifestyle factors and high CRP among middle-aged men living in Shanghai, China... - Body mass index and the risk of cancers of the gastric cardia and distal stomach in Shanghai, ChinaB T Ji
Division of Epidemiology, Columbia University, School of Public Health, New York, New York 10032, USA
Cancer Epidemiol Biomarkers Prev 6:481-5. 1997..Our observations in China support recent findings in Western populations that obesity contributes to the risk of gastric cardia cancer, especially among men... - Variation in nutrient intakes among women in Shanghai, ChinaH Cai
Department of Medicine, Center for Health Services Research and Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA
Eur J Clin Nutr 58:1604-11. 2004..Cultural practices as well as seasonal supply and consumption patterns of vegetable intake are likely the major contributors to the variation. Implications of these results are discussed... - Anthropometric predictors of coronary heart disease in Chinese womenX Zhang
Department of Medicine, Center for Health Services Research, Vanderbilt University, Nashville, TN, USA
Int J Obes Relat Metab Disord 28:734-40. 2004..9 (1.0-8.4) for the elderly. CONCLUSIONS: WHR was positively associated with the risk of CHD in both younger and older women, while other anthropometrics, including BMI, were related to CHD risk primarily among younger women... - Body mass index at various ages and mortality in Chinese women: impact of potential methodological biasesX Zhang
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
Int J Obes (Lond) 32:1130-6. 2008..Inadequate control for potential methodological biases has been suggested as an explanation for the conflicting findings concerning the relationship between body mass index (BMI) and mortality... - Energy balance and type 2 diabetes: a report from the Shanghai Women's Health StudyR Villegas
Department of Medicine, Vanderbilt Epidemiology Center, 2525 West End Avenue, Suite 600, Nashville, TN 37203, USA
Nutr Metab Cardiovasc Dis 19:190-7. 2009..The aim of this study was to examine the components of energy balance and the incidence of T2D in a cohort of middle-aged women... - Soyfood consumption and risk of glycosuria: a cross-sectional study within the Shanghai Women's Health StudyG Yang
Center for Health Service Research, Vanderbilt University Medical Center, Nashville, TN 37232 8300, USA
Eur J Clin Nutr 58:615-20. 2004..To assess the association between soyfood intake and risk of glycosuria... - Dietary patterns and blood pressure among middle-aged and elderly Chinese men in ShanghaiSang Ah Lee
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, 2525 West End Avenue, Suite 600, IMPH, Nashville TN 37203 1738, USA
Br J Nutr 104:265-75. 2010..Results of the present study suggest an important role for diet in the prevention of hypertension... - Duration of breast-feeding and the incidence of type 2 diabetes mellitus in the Shanghai Women's Health StudyR Villegas
Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Department of Medicine, Vanderbilt University Medical Center, 2525 West End Avenue, Suite 600, Nashville, TN 37232 1738, USA
Diabetologia 51:258-66. 2008..The aim of this study was to examine the association between lifetime breast-feeding and the incidence of type 2 diabetes mellitus in a large population-based cohort study of middle-aged women... - Body fat distribution and risk of diabetes among Chinese womenA D Rosenthal
Department of Medicine and Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA
Int J Obes Relat Metab Disord 28:594-9. 2004..CONCLUSIONS: Our data indicated that central obesity is a stronger risk factor for diabetes than overall obesity, suggesting that WHR may be a better indicator of risk of diabetes than BMI among Chinese women... - Validity and reproducibility of the food frequency questionnaire used in the Shanghai Women's Health StudyX O Shu
Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt Center for Health Services Research, Vanderbilt University, Nashville, TN 37232 8300, USA
Eur J Clin Nutr 58:17-23. 2004..These data indicate that the SWHS FFQ can reliably and accurately measure usual intake of major nutrients and food groups among women in Shanghai... - Dietary intake of calcium, fiber and other micronutrients in relation to colorectal cancer risk: Results from the Shanghai Women's Health StudyAesun Shin
Department of Medicine, Center for Health Services Research and Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN 37232-2587, USA
Int J Cancer 119:2938-42. 2006..Our results suggest that calcium may be protective against colorectal cancer development even at a lower consumption level compared to Western populations... - Prospective study of dietary carbohydrates, glycemic index, glycemic load, and incidence of type 2 diabetes mellitus in middle-aged Chinese womenRaquel Villegas
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, 2525 West End Ave, Ste 600, Nashville, TN 37203 1738, USA
Arch Intern Med 167:2310-6. 2007..Much uncertainty exists about the role of dietary glycemic index and glycemic load in the development of type 2 diabetes mellitus, especially in populations that traditionally subsist on a diet high in carbohydrates... - Legume and soy food intake and the incidence of type 2 diabetes in the Shanghai Women's Health StudyRaquel Villegas
Department of Medicine, Vanderbilt Epidemiology Center, Nashville, TN 37203 1738, USA
Am J Clin Nutr 87:162-7. 2008..It has been postulated that a diet high in legumes may be beneficial for the prevention of type 2 diabetes mellitus (type 2 DM). However, data linking type 2 DM risk and legume intake are limited... - Sociodemographic, behavioral, and reproductive factors associated with weight gain in Chinese womenW Wen
Department of Medicine, Vanderbilt University, Nashville, TN, USA
Int J Obes Relat Metab Disord 27:933-40. 2003..To examine whether certain sociodemographic, behavioral, and reproductive factors are associated with an increased weight gain in Chinese women... - Prevalence of obesity and correlations with lifestyle and dietary factors in Chinese menSang Ah Lee
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, Tennessee, USA
Obesity (Silver Spring) 16:1440-7. 2008..To estimate the age-adjusted prevalence of general and centralized obesity among Chinese men living in urban Shanghai... - Vegetable but not fruit consumption reduces the risk of type 2 diabetes in Chinese womenRaquel Villegas
Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Nashville, TN 37203 1738, USA
J Nutr 138:574-80. 2008..Fruit intake was not associated with the incidence of diabetes in this population. Our data suggest that vegetable consumption may protect against the development of T2D... - Dietary and lifestyle predictors of age at natural menopause and reproductive span in the Shanghai Women's Health StudyTsogzolmaa Dorjgochoo
Department of Medicine, Vanderbilt Epidemiology Center, School of Medicine, Vanderbilt University and Vanderbilt Ingram Cancer Center, Nashville, TN 37203 1738, USA
Menopause 15:924-33. 2008..We evaluated the impact of dietary, lifestyle and reproductive factors on age at natural menopause and reproductive span in Chinese women... - Nutrient intake among Chinese women living in Shanghai, ChinaZhi Chen
Department of Medicine, Center for Health Services Research and Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232-8300, USA
Br J Nutr 96:393-9. 2006.... - Adolescent and adult soy food intake and breast cancer risk: results from the Shanghai Women's Health StudySang Ah Lee
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
Am J Clin Nutr 89:1920-6. 2009..Soy food is a rich source of isoflavones--a class of phytoestrogens that has both antiestrogenic and anticarcinogenic properties... - Association of passive smoking by husbands with prevalence of stroke among Chinese women nonsmokersXianglan Zhang
Department of Medicine and Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA
Am J Epidemiol 161:213-8. 2005..The authors found that women nonsmokers who lived with husbands who smoked had an elevated prevalence of stroke, and prevalence increased with increasing intensity and duration of husbands' smoking... - Oral contraceptive use and risk of diabetes among Chinese womenAron D Rosenthal
Department of Medicine, Center for Health Services Research and the Vanderbilt-Ingram Cancer Center, Vanderbilt University, 6009 Medical Center East, 1215 21st Avenue South, Nashville, TN 37232, USA
Contraception 69:251-7. 2004..However, the attributable risk for diabetes among OC users in the general population, if confirmed by further studies, appears to be small... - Physical activity and the incidence of type 2 diabetes in the Shanghai women's health studyRaquel Villegas
Department of Medicine, Vanderbilt Epidemiology Center Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
Int J Epidemiol 35:1553-62. 2006.... - Spousal correlations for lifestyle factors and selected diseases in Chinese couplesAdriana L Jurj
Department of Medicine, Center for Health Services Research and Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA
Ann Epidemiol 16:285-91. 2006.... - Population-based, case-control study of blood C-peptide level and breast cancer riskG Yang
Department of Medicine and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-8300, USA
Cancer Epidemiol Biomarkers Prev 10:1207-11. 2001..The results from this study were consistent with the insulin-resistance hypothesis for breast cancer and suggest that increased levels of C-peptide may contribute to the development of breast cancer... - Prospective cohort study of soy food consumption and risk of bone fracture among postmenopausal womenXianglan Zhang
Department of Medicine, Center for Health Services Research, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tenn. 37232-8300, USA
Arch Intern Med 165:1890-5. 2005..Similar results were also found for intake of isoflavones. CONCLUSION: Soy food consumption may reduce the risk of fracture in postmenopausal women, particularly among those in the early years following menopause... - Birthweight, childhood growth and hypertension in adulthoodMingfang Zhao
Center for Health Services Research, Vanderbilt University, Nashville, TN 37232-8300, USA
Int J Epidemiol 31:1043-51. 2002..04). CONCLUSION: Our study suggests that low BW, particularly if accompanied by accelerated childhood growth, may increase the risk of early onset hypertension in adulthood... - Intra-person variation of urinary biomarkers of oxidative stress and inflammationXiaoyan Wu
Division of Epidemiology, Vanderbilt University Medical Center, 2525 West End Avenue, Nashville, TN 37203 1738, USA
Cancer Epidemiol Biomarkers Prev 19:947-52. 2010..However, little information is available regarding the intra-person variation of these biomarkers, hindering their application in epidemiologic studies... - General and abdominal adiposity and risk of stroke in Chinese womenXianglan Zhang
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tenn 37203 1738, USA
Stroke 40:1098-104. 2009..Although both general and abdominal adiposity are well-established risk factors for coronary heart disease, their associations with stroke are less well characterized, particularly in generally lean Asian populations... - Reproducibility and validity of the Shanghai Women's Health Study physical activity questionnaireCharles E Matthews
Department of Medicine, Vanderbilt Ingram Cancer Center, Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN 37232 8300, USA
Am J Epidemiol 158:1114-22. 2003..88). These data indicate that the SWHS PAQ is a reproducible and valid measure of exercise behaviors and that it demonstrates utility in stratifying women by levels of important lifestyle activities (e.g., housework, walking, cycling)... - Dietary carbohydrates, fiber, and breast cancer risk in Chinese womenWanqing Wen
Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN 37203 1738, USA
Am J Clin Nutr 89:283-9. 2009..Few studies have investigated the association of dietary carbohydrate and fiber intake with breast cancer risk in women in China, where carbohydrate intake is traditionally high... - Prevalence and determinants of metabolic syndrome according to three definitions in middle-aged Chinese menRaquel Villegas
Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37203 1738, USA
Metab Syndr Relat Disord 7:37-45. 2009..We estimated the prevalence and lifestyle risk factors of metabolic syndrome according to three definitions of metabolic syndrome in urban Chinese men participating in the Shanghai Men's Health Study (SMHS)... - Resting heart rate and risk of type 2 diabetes in womenXianglan Zhang
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA
Int J Epidemiol 39:900-6. 2010..Resting heart rate has been shown to predict risk of cardiovascular disease; its association with diabetes remains unclear, particularly in non-Western populations... - Animal origin foods and colorectal cancer risk: a report from the Shanghai Women's Health StudySang Ah Lee
Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, 2525 West End Avenue, Nashville, TN 37203 1738, USA
Nutr Cancer 61:194-205. 2009..The latter was positively associated with colon cancer (RR = 1.4 for ever vs. never, 95% CI = 1.1-1.9). A possible role of cholesterol and environmental pollution in the etiology of CRC was suggested... - Oxidative stress, obesity, and breast cancer risk: results from the Shanghai Women's Health StudyQi Dai
Department of Medicine and Pharmacology, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Nashville, TN 37203 1738, USA
J Clin Oncol 27:2482-8. 2009..No prospective study has investigated whether levels of 15-F(2t)-isoprostane (15-F(2t)-IsoP) and its metabolite 2,3-dinor-5,6-dihydro-15-F(2t)-IsoP (15-F(2t)-IsoPM) are related to breast cancer risk... 
Association between body-mass index and risk of death in more than 1 million AsiansWei Zheng
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN, USA
N Engl J Med 364:719-29. 2011..Most studies that have evaluated the association between the body-mass index (BMI) and the risks of death from any cause and from specific causes have been conducted in populations of European origin...- Pregnancy, childrearing, and risk of stroke in Chinese womenXianglan Zhang
Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt University Medical Center, Sixth Floor, Suite 600, 2525 West End Avenue, Nashville, TN 37203 1738, USA
Stroke 40:2680-4. 2009..Although it has been suggested that high gravidity and parity increase the risk for coronary heart disease, their associations with stroke are unclear... - Dietary calcium and magnesium intakes and the risk of type 2 diabetes: the Shanghai Women's Health StudyRaquel Villegas
Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN 37203 1738, USA
Am J Clin Nutr 89:1059-67. 2009..Diet plays a key role in the development of type 2 diabetes (T2D), but little is known about the contributions of specific nutrients in populations in which dietary patterns differ from Western populations... - Dietary polyunsaturated fatty acids and breast cancer risk in Chinese women: a prospective cohort studyHarvey J Murff
Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
Int J Cancer 128:1434-41. 2011..The relative amounts of n-6 PUFA to marine-derived n-3 PUFAs may be more important for breast cancer risk than individual dietary amounts of these fatty acids... - Fruit and vegetable consumption and risk of distal gastric cancer in the Shanghai Women's and Men's Health studiesMeira Epplein
Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, 2525 West End Avenue, Sixth Floor, Nashville, TN 37203, USA
Am J Epidemiol 172:397-406. 2010..67). No associations between dietary intakes of select antioxidant micronutrients were seen for men or women. Fruit intake is inversely associated with distal gastric cancer risk among men in Shanghai, China... - Is green tea drinking associated with a later onset of breast cancer?Qi Dai
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, TN 37203 1738, USA
Ann Epidemiol 20:74-81. 2010..Because of the substantial difference in levels of estrogens between premenopausal and postmenopausal women, the relationship between tea consumption and breast cancer risk may depend on menopausal status... - Soy food consumption is associated with lower risk of coronary heart disease in Chinese womenXianglan Zhang
Department of Medicine, Center for Health Services Research, Vanderbilt University, Nashville, TN 37232, USA
J Nutr 133:2874-8. 2003..14; 95% CI, 0.04-0.48 for the highest vs. the lowest quartile of intake; P for trend = 0.001). This study provides, for the first time, direct evidence that soy food consumption may reduce the risk of CHD in women... - Dietary patterns are associated with lower incidence of type 2 diabetes in middle-aged women: the Shanghai Women's Health StudyRaquel Villegas
Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN, USA
Int J Epidemiol 39:889-99. 2010..Data linking risk of type 2 diabetes (T2D) and dietary patterns in Chinese populations are scarce... - A prospective study of dietary polyunsaturated fatty acids and colorectal cancer risk in Chinese womenHarvey J Murff
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
Cancer Epidemiol Biomarkers Prev 18:2283-91. 2009..03). These results suggest that dietary PUFA and the ratio of n-6 to n-3 PUFA intake may be positively associated with colorectal cancer risk, and this association may be mediated in part through PGE(2) production... - A prospective study of dietary patterns and mortality in Chinese womenHui Cai
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashvill, TN, USA
Epidemiology 18:393-401. 2007..Our study prospectively examines the relationship of dietary patterns with total mortality and cause-specific mortality in a population-based cohort study of Chinese women... - Influence of exercise, walking, cycling, and overall nonexercise physical activity on mortality in Chinese womenCharles E Matthews
Department of Medicine, Division of General Internal Medicine and Public Health, Vanderbilt Epidemiology Center, Vanderbilt University Medical School, Nashville, TN 37203 1738, USA
Am J Epidemiol 165:1343-50. 2007..62, 0.99). These findings add new evidence that overall physical activity levels are an important determinant of longevity, and that health benefit can be obtained through an active lifestyle, exercise, or combinations of both... - Genetic polymorphisms in the TGF-beta 1 gene and breast cancer survival: a report from the Shanghai Breast Cancer StudyXiao Ou Shu
Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA
Cancer Res 64:836-9. 2004..4, 95% confidence interval, 1.0-1.9). Our study suggests that genetic polymorphisms in the TGF-beta1 gene may play a role in breast cancer progression... - Dietary patterns and their correlates among middle-aged and elderly Chinese men: a report from the Shanghai Men's Health StudyHui Cai
Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232 8300, USA
Br J Nutr 98:1006-13. 2007..Future studies of diet and health in this population will need to carefully take into account these potential confounders... - The Shanghai Women's Health Study: rationale, study design, and baseline characteristicsWei Zheng
Center for Health Services Research, Department of Medicine, Vanderbilt University, Nashville, TN 37232 8300, USA
Am J Epidemiol 162:1123-31. 2005..The resources from the cohort will be valuable in future studies of environmental exposures and biomarkers for the risk of cancer and other chronic diseases... - Physical activity patterns and their correlates among Chinese men in ShanghaiSang Ah Lee
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN 37203 1738, USA
Med Sci Sports Exerc 39:1700-7. 2007..Physical activity (PA) is inversely related to the risk of many chronic diseases. Understanding PA patterns and their correlates thus has significant public health implications... - Environmental tobacco smoke and mortality in Chinese women who have never smoked: prospective cohort studyWanqing Wen
Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
BMJ 333:376. 2006.... - Prospective study of urinary prostaglandin E2 metabolite and colorectal cancer riskQiuyin Cai
Department of Medicine, Center for Epidemiology Research, and Vanderbilt-Ingram Cancer Center, Nashville, TN, USA
J Clin Oncol 24:5010-6. 2006..4, 95% CI, 1.5 to 13.3; P for trend = .012) of follow-up. CONCLUSION: Given its strong association with colorectal cancer risk, urinary PGE-M may be a promising biomarker for risk assessment of this common malignancy... - The Shanghai Women's Asthma and Allergy Study: objectives, design, and recruitment resultsTina V Hartert
Division of Allergy, Pulmonary and Critical Care Medicine, School of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232 8300, USA
Am J Epidemiol 167:1387-96. 2008..This paper describes the study objectives, design, population demographics, and recruitment results... - Abdominal adiposity and mortality in Chinese womenXianglan Zhang
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37232 8300, USA
Arch Intern Med 167:886-92. 2007..Increased abdominal adiposity has been linked to an increase in mortality in populations where many are overweight or obese; it is unclear whether the same is true in relatively lean populations... - Urinary polyphenols and breast cancer risk: results from the Shanghai Women's Health StudyJianfeng Luo
Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
Breast Cancer Res Treat 120:693-702. 2010..In conclusion, high epicatechin may be related to a reduced risk of breast cancer. Further studies are warranted to confirm our findings... - Sources of variation in nutrient intakes among men in Shanghai, ChinaHui Cai
Department of Medicine, Center for Health Services Research and Vanderbilt-Ingram Cancer Center, 6009 MCE, Vanderbilt University, 1215 21st Avenue, Nashville, TN 37232-8300, USA
Public Health Nutr 8:1293-9. 2005..Further dietary validation studies in the same population could be adequately carried out with only 12 days of dietary recalls, if 100 participants were enrolled... - Validity and reproducibility of the food-frequency questionnaire used in the Shanghai men's health studyRaquel Villegas
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Medical Center East, Suite 6000, 1215 21st Avenue South, Nashville, TN 37232 8300, USA
Br J Nutr 97:993-1000. 2007..8 and 49.2%, while misclassification to opposite quartiles was between 1.5 and 6.2%. These data indicate that the SMHS FFQ can reasonably categorise usual intake of nutrients and food groups among men living in urban Shanghai... - Longitudinal study of soy food intake and blood pressure among middle-aged and elderly Chinese womenGong Yang
Vanderbilt Center for Health Services Research, Department of Medicine, Vanderbilt School of Medicine, and Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA
Am J Clin Nutr 81:1012-7. 2005..0, -1.9 mm Hg) for systolic BP and -2.2 mm Hg (95% CI: -3.8, -0.6 mm Hg) for diastolic BP. CONCLUSION: Usual intake of soy foods was inversely associated with both systolic and diastolic BPs, particularly among elderly women... - Relation of blood pressure components and categories and all-cause, stroke and coronary heart disease mortality in urban Chinese women: a population-based prospective studyTsogzolmaa Dorjgochoo
Department of Medicine, Vanderbilt Epidemiology Center, School of Medicine, and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA
J Hypertens 27:468-75. 2009..To determine whether various levels of blood pressure (BP), particularly normal and high normal BP or prehypertension, predict cardiovascular mortality among urban Chinese women... - Plasma carotenoids, tocopherols, retinol and breast cancer risk: results from the Shanghai Women Health Study (SWHS)Tsogzolmaa Dorjgochoo
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA
Breast Cancer Res Treat 117:381-9. 2009..Our results do not support an overall protective effect of lipophilic antioxidants on breast cancer risk. The few inverse associations observed for subtype of carotenoids may need to be confirmed in future studies... - Use of oral contraceptives, intrauterine devices and tubal sterilization and cancer risk in a large prospective study, from 1996 to 2006Tsogzolmaa Dorjgochoo
Vanderbilt Epidemiology Center, Department of Medicine, School of Medicine, Vanderbilt University, Nashville, TN 37203 1738, USA
Int J Cancer 124:2442-9. 2009..Although chance findings are a likely explanation for some of the associations found in our study, these findings suggest that various contraceptive methods or reproductive patterns may play a role in the etiology of cancer... - Occupation and breast cancer risk among Shanghai women in a population-based cohort studyBu Tian Ji
National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20852, USA
Am J Ind Med 51:100-10. 2008..A total of 74,942 female subjects were recruited in a population-based cohort study in Shanghai, China between 1997 and 2000. We examined the relationship between occupation and breast cancer risk... - Ginseng intake and gastric cancer risk in the Shanghai Women's Health Study cohortFarin Kamangar
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Room 3034, Bethesda, MD 20892-7232, USA
Cancer Epidemiol Biomarkers Prev 16:629-30. 2007 - Rapid increase in colorectal cancer rates in urban Shanghai, 1972-97, in relation to dietary changesWei Cheng You
Peking University School of Oncology and Beijing Institute for Cancer Research, Beijing, China 100036
J Cancer Epidemiol Prev 7:143-6. 2002..These changes were even more pronounced for colon cancer. The reasons for the rapid increases in cancer rates are not fully understood, but may involve dietary habits that have changed substantially overthe past two decades... - Family history of cancer and risk of lung cancer among nonsmoking Chinese womenYawei Zhang
School of Epidemiology and Public Health, Yale University, 60 College Street, LEPH 440, New Haven, CT 06520, USA
Cancer Epidemiol Biomarkers Prev 16:2432-5. 2007..The associations were stronger when a sibling, rather than a parent, was affected. The apparent link between lung cancer risk and a family history of colorectal, stomach, and pancreas cancers may be worth further investigation... - Menstrual and reproductive factors and gastric cancer risk in a large prospective study of womenNeal D Freedman
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
Gut 56:1671-7. 2007..Gastric cancer incidence rates are consistently lower in women than men in both high and low-risk regions worldwide. Sex hormones, such as progesterone and estrogen, may protect women against gastric cancer... - Population genetics for Y-STRs haplotypes of Chinese Ewenki ethnic minority groupBofeng Zhu
The Key Laboratory of Public Health of Ministry for Forensic Sciences, Xi an Jiaotong University, Yan Ta West Road No 76 Xi an 710061, Shaanxi, PR China
J Forensic Sci 50:969-71. 2005..The Ewenki people have no written script but a spoken language with three dialects belonging to the Manchu-Tungusic group of the Altai language family. Raising reindeers is the key livelihood of Ewenkis... - The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesisGong Yang
Department of Pathology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Proc Natl Acad Sci U S A 103:16472-7. 2006..Therefore, Gro-1 may be a therapeutic target as well as a diagnostic marker in ovarian cancer... - Up-regulation of tumor susceptibility gene 101 protein in ovarian carcinomas revealed by proteomics analysesTravis W Young
Department of Pharmacology and Toxicology, Sealy Center for Cancer Cell Biology, School of Medicine, The University of Texas Medical Branch, Galveston, Texas 77555, USA
Mol Cell Proteomics 6:294-304. 2007..These results demonstrate that TSG101 is important for CITED2- and HIF-1alpha-mediated cellular regulation in ovarian carcinomas... - Activation of BTAK expression in primary ovarian surface epithelial cells of prophylactic ovariesZhihong Zhang
Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 4095, USA
Mod Pathol 20:1078-84. 2007..This activation may be a key early genetic event in the development of hereditary ovarian cancer... - Inhibition of breast and ovarian tumor growth through multiple signaling pathways by using retrovirus-mediated small interfering RNA against Her-2/neu gene expressionGong Yang
Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030-4095, USA
J Biol Chem 279:4339-45. 2004..siRNA-mediated gene silencing of Her-2/neu and increasing the expression of thrombospondin-1 may be a useful therapeutic strategy for Her-2/neu-over-expressing breast or ovarian cancer... - Mitochondrial manganese-superoxide dismutase expression in ovarian cancer: role in cell proliferation and response to oxidative stressYumin Hu
Department of Molecular Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
J Biol Chem 280:39485-92. 2005.... - Activation of antioxidant pathways in ras-mediated oncogenic transformation of human surface ovarian epithelial cells revealed by functional proteomics and mass spectrometryTravis W Young
Department of Pharmacology and Toxicology, Sealy Center for Structural Biology, School of Medicine, The University of Texas Medical Branch, Galveston, USA
Cancer Res 64:4577-84. 2004..It is conceivable that an enhanced antioxidation capability may constitute a common mechanism for tumor cells to evade apoptosis induced by oxidative stresses at high ROS levels...
Research Grants
- Inflammatory Biomarkers and Colorectal Cancer RiskGong Yang; Fiscal Year: 2007..Overall, this study will contribute significantly to the understanding of the role of inflammation in the etiology of CRC and to the development of new strategies for the assessment of CRC risk. ..
- Inflammatory Biomarkers and Colorectal Cancer RiskGong Yang; Fiscal Year: 2010..Overall, this study will contribute significantly to the understanding of the role of inflammation in the etiology of CRC and to the development of new strategies for the assessment of CRC risk. ..