Mary K Washington

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. ncbi Expression of beta-catenin, alpha-catenin, and E-cadherin in Barrett's esophagus and esophageal adenocarcinomas
    K Washington
    Department of Pathology, Vanderbilt University Medical Center, Vanderbilt Cancer Center, Nashville, Tennessee 37232 2561, USA
    Mod Pathol 11:805-13. 1998
  2. ncbi Histopathology of ulcerative colitis in initial rectal biopsy in children
    Kay Washington
    Department of Pathology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Am J Surg Pathol 26:1441-9. 2002
  3. ncbi Interactions of the p53 protein family in cellular stress response in gastrointestinal tumors
    Anna E Vilgelm
    Department of Surgery and Cancer Biology, Vanderbilt University Medical School, Nashville, Tennessee, USA
    Mol Cancer Ther 9:693-705. 2010
  4. ncbi Distinguishing Ménétrier's disease from its mimics
    Amy Rich
    Department of Medicine, Vanderbilt University Medical Center and Nashville Veterans Affairs Medical Center, Nashville, Tennessee, USA
    Gut 59:1617-24. 2010
  5. ncbi Regulation of p53 tumor suppressor by Helicobacter pylori in gastric epithelial cells
    Jinxiong Wei
    Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Gastroenterology 139:1333-43. 2010
  6. ncbi Dopamine and cAMP regulated phosphoprotein MW 32 kDa is overexpressed in early stages of gastric tumorigenesis
    Kaushik Mukherjee
    Department of Surgery, Section of Surgical Sciences, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Surgery 148:354-63. 2010
  7. ncbi Proteomic profiling of mucosal and submucosal colonic tissues yields protein signatures that differentiate the inflammatory colitides
    Amosy E M'Koma
    Department of Biochemistry and Cancer Biology, Meharry Medical College, Nashville, Tennessee 37208 3599, USA
    Inflamm Bowel Dis 17:875-83. 2011
  8. ncbi Regulation of gastric B cell recruitment is dependent on IL-17 receptor A signaling in a model of chronic bacterial infection
    Holly M Scott Algood
    Veterans Affairs Tennessee Valley Healthcare System, Nashville, TN 37212, USA
    J Immunol 183:5837-46. 2009
  9. ncbi Claudin-1 up-regulates the repressor ZEB-1 to inhibit E-cadherin expression in colon cancer cells
    Amar B Singh
    Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Gastroenterology 141:2140-53. 2011
  10. ncbi Autoimmune liver disease: overlap and outliers
    Mary K Washington
    Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, USA
    Mod Pathol 20:S15-30. 2007

Collaborators

Detail Information

Publications23

  1. ncbi Expression of beta-catenin, alpha-catenin, and E-cadherin in Barrett's esophagus and esophageal adenocarcinomas
    K Washington
    Department of Pathology, Vanderbilt University Medical Center, Vanderbilt Cancer Center, Nashville, Tennessee 37232 2561, USA
    Mod Pathol 11:805-13. 1998
    ....
  2. ncbi Histopathology of ulcerative colitis in initial rectal biopsy in children
    Kay Washington
    Department of Pathology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Am J Surg Pathol 26:1441-9. 2002
    ..This difference may be related to a shorter duration of symptoms before biopsy...
  3. ncbi Interactions of the p53 protein family in cellular stress response in gastrointestinal tumors
    Anna E Vilgelm
    Department of Surgery and Cancer Biology, Vanderbilt University Medical School, Nashville, Tennessee, USA
    Mol Cancer Ther 9:693-705. 2010
    ....
  4. ncbi Distinguishing Ménétrier's disease from its mimics
    Amy Rich
    Department of Medicine, Vanderbilt University Medical Center and Nashville Veterans Affairs Medical Center, Nashville, Tennessee, USA
    Gut 59:1617-24. 2010
    ..It is considered a clinical diagnosis that may at times be difficult to establish. Firm diagnostic criteria for MD are proposed by delineating the clinicopathological features that best differentiate MD from its mimics...
  5. ncbi Regulation of p53 tumor suppressor by Helicobacter pylori in gastric epithelial cells
    Jinxiong Wei
    Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Gastroenterology 139:1333-43. 2010
    ..These bacteria colonize a significant part of the world's population. We investigated the molecular mechanisms of p53 regulation in H pylori-infected cells...
  6. ncbi Dopamine and cAMP regulated phosphoprotein MW 32 kDa is overexpressed in early stages of gastric tumorigenesis
    Kaushik Mukherjee
    Department of Surgery, Section of Surgical Sciences, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Surgery 148:354-63. 2010
    ..Gastric adenocarcinoma is a leading cause of cancer mortality. The role of dopamine and cAMP regulated phosphoprotein MW 32 kDa (DARPP-32) overexpression in the gastric tumorigenesis cascade remains unclear...
  7. ncbi Proteomic profiling of mucosal and submucosal colonic tissues yields protein signatures that differentiate the inflammatory colitides
    Amosy E M'Koma
    Department of Biochemistry and Cancer Biology, Meharry Medical College, Nashville, Tennessee 37208 3599, USA
    Inflamm Bowel Dis 17:875-83. 2011
    ..As a pilot study, we evaluated the ability of histology-directed MALDI-MS to determine the proteomic patterns for potential differences between CC and UC specimens...
  8. ncbi Regulation of gastric B cell recruitment is dependent on IL-17 receptor A signaling in a model of chronic bacterial infection
    Holly M Scott Algood
    Veterans Affairs Tennessee Valley Healthcare System, Nashville, TN 37212, USA
    J Immunol 183:5837-46. 2009
    ..In contrast to many chronic inflammatory diseases in which IL-17RA signaling promotes an inflammatory response, IL-17RA signaling down-regulates the chronic mononuclear inflammation elicited by H. pylori infection...
  9. ncbi Claudin-1 up-regulates the repressor ZEB-1 to inhibit E-cadherin expression in colon cancer cells
    Amar B Singh
    Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Gastroenterology 141:2140-53. 2011
    ..Up-regulation of claudin-1 reduces expression of E-cadherin. We investigated the mechanisms by which claudin-1 regulates E-cadherin expression and its effects in colon cancer cells...
  10. ncbi Autoimmune liver disease: overlap and outliers
    Mary K Washington
    Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, USA
    Mod Pathol 20:S15-30. 2007
    ..Sequential syndromes with transition from one form of autoimmune liver disease to another are rare...
  11. ncbi Adult pancreatic acinar cells give rise to ducts but not endocrine cells in response to growth factor signaling
    Stacy A Blaine
    Department of Surgery, Vanderbilt University Medical Center, Nashville, TN 37232 0443, USA
    Development 137:2289-96. 2010
    ..We conclude that apparent pancreatic plasticity can result both from the ability of acinar cells to change fate and of endocrine cells to reorganize in association with duct structures...
  12. ncbi Lymphovascular invasion in colorectal cancer: an interobserver variability study
    Elizabeth I Harris
    Department of Pathology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Am J Surg Pathol 32:1816-21. 2008
    ..This study was undertaken to examine such interobserver variability, and we hypothesized that the use of immunohistochemical markers for vascular and lymphatic channels could improve interobserver agreement...
  13. ncbi Epithelial-mesenchymal transition markers in pancreatic ductal adenocarcinoma
    Justin M M Cates
    Department of Pathology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Pancreas 38:e1-6. 2009
    ..Selected EMT markers were studied in a series of pancreatic ductal adenocarcinomas (PDAs) and benign pancreatic tissues to determine whether expression levels correlated with diagnosis, histologic grade, or patient outcome...
  14. ncbi The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor
    Anne E Powell
    Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Cell 149:146-58. 2012
    ....
  15. ncbi Efficacy of cetuximab in the treatment of Menetrier's disease
    William H Fiske
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Sci Transl Med 1:8ra18. 2009
    ..Cetuximab should be considered as first-line therapy for Ménétrier's disease...
  16. ncbi Interaction of Helicobacter pylori with gastric epithelial cells is mediated by the p53 protein family
    Jinxiong Wei
    Department of Surgery, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, Tennessee, USA
    Gastroenterology 134:1412-23. 2008
    ..Accumulating evidence suggests that both p73 and p63 play important roles in regulation of apoptosis, cell differentiation, and therapeutic drug sensitivity...
  17. ncbi MTGR1 is required for tumorigenesis in the murine AOM/DSS colitis-associated carcinoma model
    Caitlyn W Barrett
    Department of Medicine Gastroenterology, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Cancer Res 71:1302-12. 2011
    ..This represents the first report functionally linking MTGR1 to intestinal tumorigenesis...
  18. ncbi Evolution of the restorative proctocolectomy and its effects on gastrointestinal hormones
    Amosy E M'Koma
    Section of Surgical Sciences, Vanderbilt University School of Medicine, Nashville, TN 37232 2765, USA
    Int J Colorectal Dis 22:1143-63. 2007
    ..In this review, we summarize the evolution of the RPC and its effects on the GI hormones as well as their possible clinical implications...
  19. ncbi TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer
    Nipun B Merchant
    Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232 8355, USA
    Clin Cancer Res 14:1182-91. 2008
    ..TACE/ADAM-17 (tumor necrosis factor-alpha converting enzyme/a disintegrin and metalloprotease) has been implicated in ectodomain cleavage of TGF-alpha and amphiregulin...
  20. ncbi Development of a mechanical testing assay for fibrotic murine liver
    Stephanie L Barnes
    Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee 37235, USA
    Med Phys 34:4439-50. 2007
    ..In addition, future work will add the correlative method of elastography such that direct controlled validation of measurement on tissue can be determined...
  21. ncbi Protective roles of alpha-calcitonin and beta-calcitonin gene-related peptide in spontaneous and experimentally induced colitis
    Brent J Thompson
    Center for Molecular Neuroscience, Vanderbilt University School of Medicine, Nashville, TN 37232 8548, USA
    Dig Dis Sci 53:229-41. 2008
    ..These data demonstrate that both alphaCGRP and betaCGRP play a protective role in the generation of spontaneous colitis, supporting a role for both extrinsic and intrinsic CGRP-containing neurons...
  22. ncbi Activation of beta-catenin by carcinogenic Helicobacter pylori
    Aime T Franco
    Division of Gastroenterology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-2279, USA
    Proc Natl Acad Sci U S A 102:10646-51. 2005
    ..cag- strains or uninfected persons. These results indicate that H. pylori-induced dysregulation of beta-catenin-dependent pathways may explain in part the augmentation in the risk of gastric cancer conferred by this pathogen...
  23. ncbi Resection of mesenteric inflammatory veno-occlusive disease causing ischemic colitis
    Philip Bao
    Department of General Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    J Gastrointest Surg 9:812-7. 2005
    ..This report substantiates resolution of the inflammatory process after resection, colostomy, and reanastomosis. We review the literature and make conclusions regarding the clinical management of this disease...