Affiliation: Vanderbilt University
- A sulfilimine bond identified in collagen IVRoberto Vanacore
Division of Nephrology, Department of Medicine and Center for Matrix Biology, Vanderbilt University, Nashville, TN 37232, USA
Science 325:1230-4. 2009..This bond, the nitrogen analog of a sulfoxide, appears to have arisen at the divergence of sponge and cnidaria, an adaptation of the extracellular matrix in response to mechanical stress in metazoan evolution...
- Sulphilimine cross-links in Goodpasture's diseaseR Vanacore
Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 2372, USA
Clin Exp Immunol 164:4-6. 2011..Perturbation of the assembly or cleavage of the sulphilimine cross-links could be a key factor in the aetiology of Goodpasture's disease in susceptible individuals...
- Goodpasture's disease: molecular architecture of the autoantigen provides clues to etiology and pathogenesisVadim Pedchenko
Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2372, USA
Curr Opin Nephrol Hypertens 20:290-6. 2011....
- Molecular architecture of the Goodpasture autoantigen in anti-GBM nephritisVadim Pedchenko
Center for Matrix Biology, Division of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA
N Engl J Med 363:343-54. 2010..We compared the conformations of the antibody epitopes in Goodpasture's disease and Alport's post-transplantation nephritis with the intention of finding clues to the pathogenesis of anti-GBM glomerulonephritis...
- Bromine Is an Essential Trace Element for Assembly of Collagen IV Scaffolds in Tissue Development and ArchitectureA Scott McCall
Department of Pharmacology, Vanderbilt University School of Medicine, 451 Preston Research Building, Nashville, TN 37232, USA
Cell 157:1380-92. 2014..Thus, bromine is an essential trace element for all animals, and its deficiency may be relevant to BM alterations observed in nutritional and smoking-related disease. PAPERFLICK: ..