Research Topics
| Michael T TreadwaySummaryAffiliation: Vanderbilt University Country: USA Publications
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Detail Information
Publications
Worth the 'EEfRT'? The effort expenditure for rewards task as an objective measure of motivation and anhedoniaMichael T Treadway
Department of Psychology, Vanderbilt University, Nashville, TN, USA
PLoS ONE 4:e6598. 2009..Using the EEfRT, we test the hypothesis that effort-based decision-making is related to trait anhedonia...
Dopaminergic mechanisms of individual differences in human effort-based decision-makingMichael T Treadway
Department of Psychology, Vanderbilt University, Nashville, Tennessee 37240, USA
J Neurosci 32:6170-6. 2012..These findings highlight the role of DA signaling in striatal, prefrontal, and insular regions as key neurochemical mechanisms underlying individual differences in cost/benefit decision-making...
Reconsidering anhedonia in depression: lessons from translational neuroscienceMichael T Treadway
Department of Psychology, Vanderbilt University, Nashville, TN 37240, USA
Neurosci Biobehav Rev 35:537-55. 2011..These proposed modifications to the theoretical definition of anhedonia have implications for research, assessment and treatment of MDD...
On the use and misuse of genomic and neuroimaging science in forensic psychiatry: current roles and future directionsMichael T Treadway
Department of Psychology, Vanderbilt University, Nashville, TN 37203, USA
Child Adolesc Psychiatr Clin N Am 20:533-46. 2011....
Dopaminergic network differences in human impulsivityJoshua W Buckholtz
Department of Psychology, Vanderbilt University, Nashville, TN 37240, USA
Science 329:532. 2010..Path analysis confirmed that the impact of decreased midbrain D2/D3 autoreceptor availability on trait impulsivity is mediated in part through its effect on stimulated striatal DA release...
Mesolimbic dopamine reward system hypersensitivity in individuals with psychopathic traitsJoshua W Buckholtz
Department of Psychology, Vanderbilt University, Nashville, Tennessee, USA
Nat Neurosci 13:419-21. 2010..These findings suggest that neurochemical and neurophysiological hyper-reactivity of the dopaminergic reward system may comprise a neural substrate for impulsive-antisocial behavior and substance abuse in psychopathy...
Amping up effort: effects of d-amphetamine on human effort-based decision-makingMargaret C Wardle
Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois 60637, USA
J Neurosci 31:16597-602. 2011..These findings help elucidate neurochemical substrates of choice, with implications for neuropsychiatric diseases characterized by dopaminergic dysfunction and motivational deficits...
Effort-based decision-making in major depressive disorder: a translational model of motivational anhedoniaMichael T Treadway
Department of Psychology, Vanderbilt University, USA
J Abnorm Psychol 121:553-8. 2012..These findings offer novel support for theoretical models proposing that anhedonia in MDD may reflect specific impairments in motivation and reward-based decision-making...
Early adverse events, HPA activity and rostral anterior cingulate volume in MDDMichael T Treadway
Department of Psychology, Vanderbilt University, Nashville, TN, USA
PLoS ONE 4:e4887. 2009..In the present study, we sought to evaluate the relationships between grey matter volume, early adverse events and cortisol levels in MDD...
