H Tang

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. ncbi request reprint Regulation of calcium-sensitive tyrosine kinase Pyk2 by angiotensin II in endothelial cells. Roles of Yes tyrosine kinase and tyrosine phosphatase SHP-2
    H Tang
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Biol Chem 275:8389-96. 2000
  2. ncbi request reprint Inhibition of AT1 receptor internalization by concanavalin A blocks angiotensin II-induced ERK activation in vascular smooth muscle cells. Involvement of epidermal growth factor receptor proteolysis but not AT1 receptor internalization
    H Tang
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Biol Chem 275:13420-6. 2000
  3. ncbi request reprint 3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors block calcium-dependent tyrosine kinase Pyk2 activation by angiotensin II in vascular endothelial cells. involvement of geranylgeranylation of small G protein Rap1
    K Satoh
    Departments of Biochemistry and Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Biol Chem 276:15761-7. 2001
  4. ncbi request reprint Fyn kinase-directed activation of SH2 domain-containing protein-tyrosine phosphatase SHP-2 by Gi protein-coupled receptors in Madin-Darby canine kidney cells
    H Tang
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Biol Chem 274:12401-7. 1999
  5. ncbi request reprint Cross-talk between angiotensin II receptors and the tyrosine kinases and phosphatases
    T Inagami
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 0146, USA
    J Am Soc Nephrol 10:S57-61. 1999
  6. ncbi request reprint Proteins of the cyanobacterial photosystem I
    W Xu
    Department of Biochemistry, Biophysics and Molecular Biology, 4156 Molecular Biology Building, Iowa State University, Ames, IA 50011, USA
    Biochim Biophys Acta 1507:32-40. 2001

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Regulation of calcium-sensitive tyrosine kinase Pyk2 by angiotensin II in endothelial cells. Roles of Yes tyrosine kinase and tyrosine phosphatase SHP-2
    H Tang
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Biol Chem 275:8389-96. 2000
    ..Thus, the balance of Pyk2 tyrosine phosphorylation in response to Ang II is controlled by Yes kinase and by a tyrosine phosphatase SHP-2 in endothelial cells...
  2. ncbi request reprint Inhibition of AT1 receptor internalization by concanavalin A blocks angiotensin II-induced ERK activation in vascular smooth muscle cells. Involvement of epidermal growth factor receptor proteolysis but not AT1 receptor internalization
    H Tang
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Biol Chem 275:13420-6. 2000
    ..ConA also induced proteolysis of erbB-2 but not platelet-derived growth factor receptor. Thus, ConA blocks Ang II-induced ERK activation in VSMC through a distinct mechanism, the ConA-mediated proteolysis of the EGF receptor...
  3. ncbi request reprint 3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors block calcium-dependent tyrosine kinase Pyk2 activation by angiotensin II in vascular endothelial cells. involvement of geranylgeranylation of small G protein Rap1
    K Satoh
    Departments of Biochemistry and Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Biol Chem 276:15761-7. 2001
    ..In addition, our results indicate that 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, a class of cholesterol-lowering drugs, could interrupt Ang II signaling independent of cholesterol lowering in endothelial cells...
  4. ncbi request reprint Fyn kinase-directed activation of SH2 domain-containing protein-tyrosine phosphatase SHP-2 by Gi protein-coupled receptors in Madin-Darby canine kidney cells
    H Tang
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Biol Chem 274:12401-7. 1999
    ..Therefore, we have demonstrated for the first time that the activation of SHP-2 by these Gi protein-coupled receptors requires Fyn kinase and that there is a specific physical interaction of Fyn kinase with SHP-2 in MDCK cells...
  5. ncbi request reprint Cross-talk between angiotensin II receptors and the tyrosine kinases and phosphatases
    T Inagami
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 0146, USA
    J Am Soc Nephrol 10:S57-61. 1999
    ..The relative importance of AT1 and AT2 receptor actions depends on the levels of AT1 and AT2 receptor expression...
  6. ncbi request reprint Proteins of the cyanobacterial photosystem I
    W Xu
    Department of Biochemistry, Biophysics and Molecular Biology, 4156 Molecular Biology Building, Iowa State University, Ames, IA 50011, USA
    Biochim Biophys Acta 1507:32-40. 2001
    ..Yet, the roles of some proteins of the cyanobacterial PS I are unknown. It is necessary to examine functions of these proteins on a global scale of cell physiology, biogenesis and evolution...