Charles W Stratton

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. ncbi request reprint In vitro susceptibility testing versus in vivo effectiveness
    Charles W Stratton
    Vanderbilt University School of Medicine, 21st and Edgehill Road, Nashville, TN 37232, USA
    Med Clin North Am 90:1077-88. 2006
  2. ncbi request reprint Multiple sclerosis: an infectious syndrome involving Chlamydophila pneumoniae
    Charles W Stratton
    Department of Pathology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Trends Microbiol 14:474-9. 2006
  3. ncbi request reprint Comparative in vitro activity of telithromycin and beta-lactam antimicrobials against community-acquired bacterial respiratory tract pathogens in the United States: findings from the PROTEKT US study, 2000-2001
    Charles W Stratton
    Clinical Microbiology Laboratory, Vanderbilt University School of Medicine, Vanderbilt University Hospital, Nashville, TN 37201, USA
    Clin Ther 26:522-30. 2004
  4. ncbi request reprint Antimicrobial resistance in respiratory tract pathogens
    Charles W Stratton
    Medicine and Pathology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Expert Rev Anti Infect Ther 2:641-7. 2004
  5. pmc StaphPlex system for rapid and simultaneous identification of antibiotic resistance determinants and Panton-Valentine leukocidin detection of staphylococci from positive blood cultures
    Yi Wei Tang
    Department of Medicine, Molecular Infectious Disease Laboratory, Vanderbilt University Hospital, 4605 TVC, Nashville, TN 37232 5310, USA
    J Clin Microbiol 45:1867-73. 2007
  6. pmc Characterization of three Staphylococcus aureus isolates from a 17-year-old female who died of tampon-related toxic shock syndrome
    Yi Wei Tang
    Department of Pathology, Vanderbilt University Medical Center, and Molecular Infectious Disease Laboratory, Vanderbilt University Hospital, 4605 TVC, Nashville, TN 37232 5310, USA
    J Clin Microbiol 48:1974-7. 2010
  7. pmc Qualitative and quantitative detection of Chlamydophila pneumoniae DNA in cerebrospinal fluid from multiple sclerosis patients and controls
    Yi Wei Tang
    Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
    PLoS ONE 4:e5200. 2009
  8. doi request reprint Staphylococcus pseudolugdunensis sp. nov., a pyrrolidonyl arylamidase/ornithine decarboxylase-positive bacterium isolated from blood cultures
    Yi Wei Tang
    Department of Pathology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Diagn Microbiol Infect Dis 60:351-9. 2008
  9. pmc Clonal dissemination of Staphylococcus epidermidis in an oncology ward
    Kenneth L Muldrew
    Department of Pathology, Vanderbilt University, School of Medicine, Nashville, Tennessee, USA
    J Clin Microbiol 46:3391-6. 2008
  10. pmc Comparative evaluation of Bruker Biotyper and BD Phoenix systems for identification of bacterial pathogens associated with urinary tract infections
    Yingjun Yan
    Department of Pathology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    J Clin Microbiol 49:3936-9. 2011

Collaborators

Detail Information

Publications36

  1. ncbi request reprint In vitro susceptibility testing versus in vivo effectiveness
    Charles W Stratton
    Vanderbilt University School of Medicine, 21st and Edgehill Road, Nashville, TN 37232, USA
    Med Clin North Am 90:1077-88. 2006
    ..Finally, the clinical microbiology laboratory has advanced with improved methods as well as the adaptation of breakpoints that are more realistic...
  2. ncbi request reprint Multiple sclerosis: an infectious syndrome involving Chlamydophila pneumoniae
    Charles W Stratton
    Department of Pathology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Trends Microbiol 14:474-9. 2006
    ..MS might be an infectious syndrome in which C. pneumoniae has a role in a subset of patients. Mechanisms by which such a cryptic infection could engender relapsing-remitting and, ultimately, progressive disease patterns are discussed...
  3. ncbi request reprint Comparative in vitro activity of telithromycin and beta-lactam antimicrobials against community-acquired bacterial respiratory tract pathogens in the United States: findings from the PROTEKT US study, 2000-2001
    Charles W Stratton
    Clinical Microbiology Laboratory, Vanderbilt University School of Medicine, Vanderbilt University Hospital, Nashville, TN 37201, USA
    Clin Ther 26:522-30. 2004
    ....
  4. ncbi request reprint Antimicrobial resistance in respiratory tract pathogens
    Charles W Stratton
    Medicine and Pathology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Expert Rev Anti Infect Ther 2:641-7. 2004
    ..Recognition of these resistance mechanisms allows them to be targeted, such as with beta-lactamase inhibitors. Newly recognized resistance mechanisms such as efflux may also be targeted in the future...
  5. pmc StaphPlex system for rapid and simultaneous identification of antibiotic resistance determinants and Panton-Valentine leukocidin detection of staphylococci from positive blood cultures
    Yi Wei Tang
    Department of Medicine, Molecular Infectious Disease Laboratory, Vanderbilt University Hospital, 4605 TVC, Nashville, TN 37232 5310, USA
    J Clin Microbiol 45:1867-73. 2007
    ....
  6. pmc Characterization of three Staphylococcus aureus isolates from a 17-year-old female who died of tampon-related toxic shock syndrome
    Yi Wei Tang
    Department of Pathology, Vanderbilt University Medical Center, and Molecular Infectious Disease Laboratory, Vanderbilt University Hospital, 4605 TVC, Nashville, TN 37232 5310, USA
    J Clin Microbiol 48:1974-7. 2010
    ....
  7. pmc Qualitative and quantitative detection of Chlamydophila pneumoniae DNA in cerebrospinal fluid from multiple sclerosis patients and controls
    Yi Wei Tang
    Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
    PLoS ONE 4:e5200. 2009
    ..pneumoniae DNA in CSF. The TaqMan system may not be sensitive enough for diagnostic purposes due to the low C. pneumoniae copies existing in the majority of CSF specimens from MS patients...
  8. doi request reprint Staphylococcus pseudolugdunensis sp. nov., a pyrrolidonyl arylamidase/ornithine decarboxylase-positive bacterium isolated from blood cultures
    Yi Wei Tang
    Department of Pathology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Diagn Microbiol Infect Dis 60:351-9. 2008
    ..On the basis of the close biochemical reactions with S. lugdunensis and phylogenetic evidence, these isolates are proposed the designation Staphylococcus pseudolugdunensis sp. nov...
  9. pmc Clonal dissemination of Staphylococcus epidermidis in an oncology ward
    Kenneth L Muldrew
    Department of Pathology, Vanderbilt University, School of Medicine, Nashville, Tennessee, USA
    J Clin Microbiol 46:3391-6. 2008
    ..This study demonstrates the presence of a predominant clone among central line isolates from an OW that is not present in CoNS venipuncture isolates from an ER...
  10. pmc Comparative evaluation of Bruker Biotyper and BD Phoenix systems for identification of bacterial pathogens associated with urinary tract infections
    Yingjun Yan
    Department of Pathology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    J Clin Microbiol 49:3936-9. 2011
    ..9% and 99.5% to the genus level and 99.1% and 98.5% to the species level, respectively. Both systems provide reliable results, and the Biotyper system offers a rapid tool for urine bacterial isolate identification...
  11. pmc Identification and differentiation of clinically relevant mycobacterium species directly from acid-fast bacillus-positive culture broth
    Haijing Li
    Departments of Pathology1 and Medicine, 2 Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    J Clin Microbiol 47:3814-20. 2009
    ..intracellulare complex strains into M. avium and M. intracellulare may provide a tool to better understand the role of Mycobacterium avium-M. intracellulare complex isolates in human disease...
  12. pmc Assessment of Clostridium difficile infections by quantitative detection of tcdB toxin by use of a real-time cell analysis system
    Alex B Ryder
    Departments of Pathology and Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 5310, USA
    J Clin Microbiol 48:4129-34. 2010
    ..89 ng/ml) were significantly lower than those prior to the treatment (15.68 ng/ml, Wilcoxon P = 0.01). The study demonstrates that the RTCA assay provides a functional tool for the potential assessment of C. difficile infections...
  13. pmc Mass spectrometry biotyper system identifies enteric bacterial pathogens directly from colonies grown on selective stool culture media
    Ying He
    Departments of Pathology and Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232, 5310, USA
    J Clin Microbiol 48:3888-92. 2010
    ..The Biotyper system provides a rapid and simple screening tool for identifying many, but not all, suspicious colonies grown on selective media within 24 h after inoculation, which shortens test turnaround time by 2 to 3 days...
  14. doi request reprint Management of immune dysfunction after adult cardiac surgery
    J Scott Rankin
    Centennial Medical Center, Nashville, Tenn, USA
    J Thorac Cardiovasc Surg 142:575-80. 2011
    ..In this series, results of immune augmentation were assessed in patients experiencing pulmonary dysfunction/multiorgan failure syndrome after cardiac surgery...
  15. pmc C. Diff Quik Chek complete enzyme immunoassay provides a reliable first-line method for detection of Clostridium difficile in stool specimens
    Criziel D Quinn
    Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Clin Microbiol 48:603-5. 2010
    ..Specimens with discrepant results for GDH and toxins A/B, which comprised 13.2% of the specimens, need to be retested...
  16. pmc Dead bugs don't mutate: susceptibility issues in the emergence of bacterial resistance
    Charles W Stratton
    Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Emerg Infect Dis 9:10-6. 2003
    ..Moreover, the ketolides are associated with a low potential for inducing resistance, making them promising first-line agents for respiratory tract infections...
  17. pmc Antimicrobial susceptibility patterns and staphylococcal cassette chromosome mec types of, as well as Panton-Valentine leukocidin occurrence among, methicillin-resistant Staphylococcus aureus isolates from children and adults in middle Tennessee
    Abdullah Kilic
    Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 5310, USA
    J Clin Microbiol 44:4436-40. 2006
    ..These data indicate that SCCmec-IV MRSA isolates frequently infect children in middle Tennessee and are likely to harbor the PVL gene...
  18. pmc Improved identification of yeast species directly from positive blood culture media by combining Sepsityper specimen processing and Microflex analysis with the matrix-assisted laser desorption ionization Biotyper system
    Yingjun Yan
    Department of Pathology and Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232 5310, USA
    J Clin Microbiol 49:2528-32. 2011
    ..Our data indicated that the Sepsityper specimen processing and Microflex analysis by the MALDI Biotyper system provide a rapid and reliable tool for yeast species identification directly from positive blood culture media...
  19. doi request reprint Peripheral blood eosinophilia as a clue to the diagnosis of an occult Coccidioides infection
    Christopher M Simons
    Department of Pathology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Hum Pathol 42:449-53. 2011
    ....
  20. ncbi request reprint Urine polymerase chain reaction is not as sensitive as urine antigen for the diagnosis of disseminated histoplasmosis
    Yi Wei Tang
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Diagn Microbiol Infect Dis 54:283-7. 2006
    ..Thus, positive PCR results in urine specimens correlate with positive culture results, but not with antigenuria. The low sensitivity of this PCR assay in urine limits its use in the diagnosis of disseminated histoplasmosis...
  21. doi request reprint Staphylococcus aureus: An old pathogen with new weapons
    Yi Wei Tang
    Department of Pathology and Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Clin Lab Med 30:179-208. 2010
    ..This article addresses the emerging aspects of infections caused by S aureus, including microbiology, epidemiology, clinical presentation, pathogenesis, diagnosis, treatment and prognosis, and immunity...
  22. ncbi request reprint Association of Chlamydia pneumoniae with central nervous system disease
    Charles W Stratton
    Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, USA
    Microbes Infect 5:1249-53. 2003
    ..This review addresses the potential and the underlying mechanisms by which C. pneumoniae infections can play a role in such diverse neurological diseases as multiple sclerosis and Alzheimer's disease...
  23. ncbi request reprint The risk of valve surgery for endocarditis in patients with dialysis-dependent renal failure
    J Scott Rankin
    Centennial Medical Center, Nashville, TN, USA
    J Heart Valve Dis 16:617-22; discussion 622. 2007
    ..The study aim was to develop a simple risk scoring system to identify high-risk dialysis patients undergoing valve surgery for endocarditis...
  24. ncbi request reprint PCR detection of Histoplasma capsulatum var. capsulatum in whole blood of a renal transplant patient with disseminated histoplasmosis
    Julianne Qualtieri
    Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Ann Clin Lab Sci 39:409-12. 2009
    ..Blood fungal cultures in this case remained negative, suggesting that molecular assays may facilitate the laboratory diagnosis of disseminated histoplasmosis...
  25. doi request reprint Coccidioides, cryptococcus, or blastomyces? A diagnostic dilemma encountered during frozen section evaluation
    Colt M McClain
    Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, USA
    Pediatr Dev Pathol 15:71-5. 2012
    ..A brief overview of Blastomyces , including histopathologic features and key microscopic differences from Coccidioides and Cryptococcus , is discussed...
  26. ncbi request reprint Immunotherapy for refractory pulmonary infection after adult cardiac surgery: immune dysregulation syndrome
    J Scott Rankin
    Department of Cardiac Surgery, Vanderbilt University, 2400 Patterson Street, Suite 103, Nashville, TN 37203, USA
    J Heart Valve Dis 14:783-91. 2005
    ..Moreover, the incidence of PD/MF may be increasing due to the emergence of antibiotic-resistant pathogens...
  27. doi request reprint Sensitive, qualitative detection of human herpesvirus-6 and simultaneous differentiation of variants A and B
    Haijing Li
    Department of Pathology, Vanderbilt University School of Medicine, Nashville, TN 37232, United States
    J Clin Virol 46:20-3. 2009
    ..The current limitations of laboratory testing for the detection of human herpesvirus virus 6 (HHV-6) in clinical specimens with low HHV-6 viral loads make this area a priority for further research and development...
  28. pmc Complex febrile seizures followed by complete recovery in an infant with high-titer 2009 pandemic influenza A (H1N1) virus infection
    Mandy F O'Leary
    Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Clin Microbiol 48:3803-5. 2010
    ..Febrile seizures may be a complication in young children experiencing infection with high viral loads of 2009 H1N1 influenza virus...
  29. ncbi request reprint Outbreak of joint and soft-tissue infections associated with injections from a multiple-dose medication vial
    David L Kirschke
    Epidemiology Program Office, Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA and Tennessee Department of Health, Nashville, TN, USA
    Clin Infect Dis 36:1369-73. 2003
    ..aureus in MDVs of lidocaine revealed prolonged survival at refrigerator temperatures. This outbreak highlights the importance of strict attention to aseptic procedures and carefully following manufacturers' instructions when using MDVs...
  30. ncbi request reprint Culture and immunohistochemical evidence of Chlamydia pneumoniae infection in ulcerative pyoderma gangrenosum
    Hunter H Sams
    Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennesses, USA
    J Am Acad Dermatol 48:966-9. 2003
    ....
  31. pmc Molecular diagnosis of necrotizing fasciitis by 16S rRNA gene sequencing and superantigen gene detection
    Kenneth L Muldrew
    Molecular Infectious Disease Laboratory, Vanderbilt University Hospital, 4605 TVC, Nashville, TN 37232 5310, USA
    J Mol Diagn 7:641-5. 2005
    ..This confirmed the etiology of the patient's rapid deterioration with multisystem organ failure...
  32. pmc Acinetobacter septicus sp. nov. association with a nosocomial outbreak of bacteremia in a neonatal intensive care unit
    Abdullah Kilic
    Department of Microbiology and Clinical Microbiology, Gulhane Military Medical Academy and School of Medicine, 06018 Ankara, Turkey
    J Clin Microbiol 46:902-8. 2008
    ..We propose the designation of Acinetobacter septicus sp. nov. for these isolates, with isolate AK001 as the type strain...
  33. ncbi request reprint Chlamydia pneumoniae and acute coronary syndrome
    William M Mitchell
    N Engl J Med 353:525-8; author reply 525-8. 2005
  34. pmc Pseudomonas putida septicemia in a special care nursery due to contaminated flush solutions prepared in a hospital pharmacy
    Joseph F Perz
    Centers for Disease Control and Prevention, Office of Workforce and Career Development, Epidemic Intelligence Service, Atlanta, Georgia 30333, USA
    J Clin Microbiol 43:5316-8. 2005
    ..These findings highlight the need for compliance with current standards of aseptic technique and quality assurance during the preparation of compounded sterile products...
  35. pmc Clonal spread of serogroup W135 meningococcal disease in Turkey
    Abdullah Kilic
    Gulhane Military Medical Academy, Ankara, Turkey
    J Clin Microbiol 44:222-4. 2006
    ..These data demonstrate that serogroup W135 meningococci with different genotypes, including the Hajj epidemic strain, are endemic in Turkey...
  36. pmc PCR Enhances acid-fast bacillus stain-based rapid detection of Mycobacterium tuberculosis
    Yi Wei Tang
    J Clin Microbiol 42:1849-50. 2004