Affiliation: Vanderbilt University
- Strange K, Yan X, Lorin Nebel C, Xing J. Physiological roles of STIM1 and Orai1 homologs and CRAC channels in the genetic model organism Caenorhabditis elegans. Cell Calcium. 2007;42:193-203 pubmed..Instead, we suggest that CRAC channels carry out highly specialized and cell specific signaling roles and that they may function as a failsafe mechanism to prevent Ca(2+) store depletion under pathophysiological and stress conditions. ..