Lilianna Solnica-Krezel

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. ncbi request reprint The role of the homeodomain protein Bozozok in zebrafish axis formation
    L Solnica-Krezel
    Department of Molecular Biology, Vanderbilt University, Nashville, Tennessee 37235, USA
    Int J Dev Biol 45:299-310. 2001
  2. ncbi request reprint Conserved patterns of cell movements during vertebrate gastrulation
    Lilianna Solnica-Krezel
    Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37235, USA
    Curr Biol 15:R213-28. 2005
  3. ncbi request reprint Gastrulation in zebrafish -- all just about adhesion?
    Lilianna Solnica-Krezel
    Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA
    Curr Opin Genet Dev 16:433-41. 2006
  4. ncbi request reprint Vertebrate development: taming the nodal waves
    Lilianna Solnica-Krezel
    Department of Biological Sciences, Vanderbilt University, VU Station B 351634, 37235 1634, Nashville, TN, USA
    Curr Biol 13:R7-9. 2003
  5. pmc Essential roles of G{alpha}12/13 signaling in distinct cell behaviors driving zebrafish convergence and extension gastrulation movements
    Fang Lin
    Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    J Cell Biol 169:777-87. 2005
  6. pmc Prostaglandin Gbetagamma signaling stimulates gastrulation movements by limiting cell adhesion through Snai1a stabilization
    Christina K Speirs
    Department of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA
    Development 137:1327-37. 2010
  7. ncbi request reprint Apelin and its receptor control heart field formation during zebrafish gastrulation
    Xin Xin I Zeng
    Vanderbilt University, Department of Biological Sciences, VU Station B 35 1634, Nashville, TN 37235, USA
    Dev Cell 12:391-402. 2007
  8. ncbi request reprint No tail co-operates with non-canonical Wnt signaling to regulate posterior body morphogenesis in zebrafish
    Florence Marlow
    Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA
    Development 131:203-16. 2004
  9. ncbi request reprint Zebrafish miR-214 modulates Hedgehog signaling to specify muscle cell fate
    Alex S Flynt
    Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37235, USA
    Nat Genet 39:259-63. 2007
  10. pmc Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements
    Jason R Jessen
    Department of Biological Sciences, Vanderbilt University, VU Station B 351634, Nashville, TN 37235, USA
    Nat Cell Biol 4:610-5. 2002

Research Grants

  1. GENETIC ANALYSIS OF CONVERGENT EXTENSION IN ZEBRAFISH
    Lilianna Solnica Krezel; Fiscal Year: 2007
  2. G alpha 12/13 Signaling in Zebrafish Embryogenesis
    Lilianna Solnica Krezel; Fiscal Year: 2007
  3. 2nd Strategic Conference of Zebrafish Investigators
    Lilianna Solnica Krezel; Fiscal Year: 2007
  4. GENETIC ANALYSIS OF CONVERGENT EXTENSION IN ZEBRAFISH
    Lilianna Solnica Krezel; Fiscal Year: 2009
  5. GENETIC ANALYSIS OF CONVERGENT EXTENSION IN ZEBRAFISH
    Lilianna Solnica Krezel; Fiscal Year: 2005
  6. GENETIC ANALYSIS OF CONVERGENT EXTENSION IN ZEBRAFISH
    Lilianna Solnica Krezel; Fiscal Year: 2000
  7. GENETIC REGULATION OF SOMITE MORPHOGENESIS IN ZEBRAFISH
    Lilianna Solnica Krezel; Fiscal Year: 2004
  8. G alpha 12/13 Signaling in Zebrafish Embryogenesis
    Lilianna Solnica Krezel; Fiscal Year: 2009

Collaborators

Detail Information

Publications46

  1. ncbi request reprint The role of the homeodomain protein Bozozok in zebrafish axis formation
    L Solnica-Krezel
    Department of Molecular Biology, Vanderbilt University, Nashville, Tennessee 37235, USA
    Int J Dev Biol 45:299-310. 2001
    ..Notably, Bozozok appears to function by repressing transcription of target genes such as swr (bmp2b) gene, and as such is the earliest acting repressor that the nascent dorsal axis is using to antagonize ventral influences...
  2. ncbi request reprint Conserved patterns of cell movements during vertebrate gastrulation
    Lilianna Solnica-Krezel
    Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37235, USA
    Curr Biol 15:R213-28. 2005
    ..Patterns of gastrulation cell movements relative to the blastopore and the organizer are similar from fish to mammals, and conserved molecular pathways mediate gastrulation movements...
  3. ncbi request reprint Gastrulation in zebrafish -- all just about adhesion?
    Lilianna Solnica-Krezel
    Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA
    Curr Opin Genet Dev 16:433-41. 2006
    ..Whereas some signaling pathways are required for a subset of these behaviors, other molecules, such as E-cadherin or Galpha12 and Galpha13 proteins, appear to have a widespread role in different gastrulation cell behaviors...
  4. ncbi request reprint Vertebrate development: taming the nodal waves
    Lilianna Solnica-Krezel
    Department of Biological Sciences, Vanderbilt University, VU Station B 351634, 37235 1634, Nashville, TN, USA
    Curr Biol 13:R7-9. 2003
    ....
  5. pmc Essential roles of G{alpha}12/13 signaling in distinct cell behaviors driving zebrafish convergence and extension gastrulation movements
    Fang Lin
    Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    J Cell Biol 169:777-87. 2005
    ..These findings provide the first evidence that Galpha(12) and Galpha(13) have overlapping and essential roles in distinct cell behaviors that drive vertebrate gastrulation...
  6. pmc Prostaglandin Gbetagamma signaling stimulates gastrulation movements by limiting cell adhesion through Snai1a stabilization
    Christina K Speirs
    Department of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA
    Development 137:1327-37. 2010
    ....
  7. ncbi request reprint Apelin and its receptor control heart field formation during zebrafish gastrulation
    Xin Xin I Zeng
    Vanderbilt University, Department of Biological Sciences, VU Station B 35 1634, Nashville, TN 37235, USA
    Dev Cell 12:391-402. 2007
    ..Our results implicate GPCR signaling in movements of discrete cell populations that establish organ rudiments during vertebrate gastrulation...
  8. ncbi request reprint No tail co-operates with non-canonical Wnt signaling to regulate posterior body morphogenesis in zebrafish
    Florence Marlow
    Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA
    Development 131:203-16. 2004
    ..Moreover, we provide genetic evidence for the notion that tail development entails a continuation of mechanisms regulating gastrulation together with mechanisms unique to the posterior body...
  9. ncbi request reprint Zebrafish miR-214 modulates Hedgehog signaling to specify muscle cell fate
    Alex S Flynt
    Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37235, USA
    Nat Genet 39:259-63. 2007
    ..We show that su(fu) mRNA, encoding a negative regulator of Hedgehog signaling, is targeted by miR-214. Through regulation of su(fu), miR-214 enables precise specification of muscle cell types by sharpening cellular responses to Hedgehog...
  10. pmc Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements
    Jason R Jessen
    Department of Biological Sciences, Vanderbilt University, VU Station B 351634, Nashville, TN 37235, USA
    Nat Cell Biol 4:610-5. 2002
    ..We propose Trilobite/Stbm mediates cellular interactions that confer directionality on distinct movements during vertebrate embryogenesis...
  11. pmc Six3 cooperates with Hedgehog signaling to specify ventral telencephalon by promoting early expression of Foxg1a and repressing Wnt signaling
    Dan Carlin
    Department of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA
    Development 139:2614-24. 2012
    ..We further find that Six3 promotes ventral telencephalic fates through transient regulation of foxg1a expression and repression of the Wnt/β-catenin pathway...
  12. ncbi request reprint New functions for a vertebrate Rho guanine nucleotide exchange factor in ciliated epithelia
    Jennifer R Panizzi
    Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA
    Development 134:921-31. 2007
    ..Our studies in zebrafish embryos have identified new, essential roles for this RhoGEF in ciliated epithelia during vertebrate development...
  13. ncbi request reprint Cyclooxygenase-1 signaling is required for vascular tube formation during development
    Yong I Cha
    Department of Medicine, Cell and Developmental Biology and Cancer Biology, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Vanderbilt University, 694 Preston Research Building, 2300 Pierce Ave, Nashville, TN 37232, USA
    Dev Biol 282:274-83. 2005
    ..Together, we provide the first evidence that COX-1 signaling is required for development of posterior mesoderm organs, specifically in the vascular tube formation and posterior nephric duct development...
  14. pmc Chemokine GPCR signaling inhibits β-catenin during zebrafish axis formation
    Shu Yu Wu
    Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, United States of America
    PLoS Biol 10:e1001403. 2012
    ..Our study delineates a novel negative, Gsk3β-independent control mechanism of β-catenin and implicates Ccr7 as a long-hypothesized GPCR regulating vertebrate axis formation...
  15. ncbi request reprint Zebrafish Rho kinase 2 acts downstream of Wnt11 to mediate cell polarity and effective convergence and extension movements
    Florence Marlow
    Department of Biological Sciences, Vanderbilt University, VU Station B 351634, Nashville, TN 37235 1634, USA
    Curr Biol 12:876-84. 2002
    ..Moreover, how defective mediolateral cell polarity impacts CE is not understood...
  16. ncbi request reprint Convergence and extension movements affect dynamic notochord-somite interactions essential for zebrafish slow muscle morphogenesis
    Chunyue Yin
    Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37235, USA
    Dev Dyn 236:2742-56. 2007
    ..We propose that in the double mutants, impaired C&E movements disrupt notochord development, which impedes the adaxial cell shape changes...
  17. pmc Cyclooxygenase-1-derived PGE2 promotes cell motility via the G-protein-coupled EP4 receptor during vertebrate gastrulation
    Yong I Cha
    Department of Medicine and Cancer Biology, Cell and Developmental Biology, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, Tennessee 37232 2279, USA
    Genes Dev 20:77-86. 2006
    ..This work demonstrates a critical requirement of PGE(2) signaling in promoting cell motility through the COX-1-Ptges-EP4 pathway, a previously unrecognized role for this biologically active lipid in early animal development...
  18. pmc Galpha12/13 regulate epiboly by inhibiting E-cadherin activity and modulating the actin cytoskeleton
    Fang Lin
    Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    J Cell Biol 184:909-21. 2009
    ..These results provide the first in vivo evidence that Galpha(12/13) regulate epiboly through two distinct mechanisms: limiting E-cadherin activity and modulating the organization of the actin cytoskeleton...
  19. pmc Functional redundancy between Cdc14 phosphatases in zebrafish ciliogenesis
    Aurélie Clément
    Howard Hughes Medical Institute and Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Dev Dyn 241:1911-21. 2012
    ..However, the question of whether CDC14 paralogs can functionally compensate for each other has yet to be addressed...
  20. pmc Six3 represses nodal activity to establish early brain asymmetry in zebrafish
    Adi Inbal
    Department of Biological Sciences, Vanderbilt University, VU Station B 351634, Nashville, TN 37235 1634, USA
    Neuron 55:407-15. 2007
    ..Our data reveal a Six3-dependent mechanism for establishment of correct brain laterality and provide an entry point to understanding the genetic regulation of Nodal signaling in the brain...
  21. ncbi request reprint Essential roles of a zebrafish prdm1/blimp1 homolog in embryo patterning and organogenesis
    Thomas P Wilm
    Vanderbilt University, Department of Biological Sciences, VU Station B 351634, Nashville, TN 37235 1634, USA
    Development 132:393-404. 2005
    ..Our studies reveal essential roles for prdm1 in limiting the function of the gastrula organizer and regulating cell fate specification and morphogenetic processes in precise correspondence with its intricate expression pattern...
  22. ncbi request reprint Convergence and extension movements mediate the specification and fate maintenance of zebrafish slow muscle precursors
    Chunyue Yin
    Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA
    Dev Biol 304:141-55. 2007
    ..Our results underscore the significance of precise coordination between cell movements and inductive tissue interactions during cell fate specification...
  23. ncbi request reprint Identification and developmental expression pattern of van gogh-like 1, a second zebrafish strabismus homologue
    Jason R Jessen
    Department of Biological Sciences, Vanderbilt University, 1210 Medical Research Building III, VU Station B, Box 35 1634, Nashville, TN 37235 1634, USA
    Gene Expr Patterns 4:339-44. 2004
    ..Injection of synthetic vangl1 RNA partially suppressed the gastrulation defect in trilobite mutant embryos, suggesting that Vangl1 and Trilobite/Vangl2 have similar biochemical activities...
  24. pmc The Cdc14B phosphatase contributes to ciliogenesis in zebrafish
    Aurélie Clément
    Howard Hughes Medical Institute and Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Development 138:291-302. 2011
    ..This first study of a loss of function of a Cdc14 family member in a vertebrate organism reveals a new role for Cdc14B in ciliogenesis and consequently in a number of developmental processes...
  25. ncbi request reprint Convergence and extension in vertebrate gastrulae: cell movements according to or in search of identity?
    Dina C Myers
    Department of Biological Sciences, Vanderbilt University, VU Station B 351634, Nashville, TN 37235 1634, USA
    Trends Genet 18:447-55. 2002
    ..Other observations suggest the intriguing possibility that positional information regulates convergence and extension movements in parallel with cell-fate specification...
  26. pmc Gpr125 modulates Dishevelled distribution and planar cell polarity signaling
    Xin Li
    Neuroscience Graduate Program, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Development 140:3028-39. 2013
    ..Our study reveals a role for Gpr125 in PCP-mediated processes and provides mechanistic insight into Wnt/PCP signaling. ..
  27. ncbi request reprint Targeted gene expression in the zebrafish prechordal plate
    Adi Inbal
    Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37235 1634, USA
    Genesis 44:584-8. 2006
    ..Thus, the use of Tg[gsc:Gal4-VP16] fish can help in understanding gene function in the prechordal plate, an embryonic structure that is crucial for normal neural patterning...
  28. ncbi request reprint Bmp activity gradient regulates convergent extension during zebrafish gastrulation
    Dina C Myers
    Department of Biological Sciences, Vanderbilt University, VU Station B 351634, Nashville, Tennessee 37235 1634, USA
    Dev Biol 243:81-98. 2002
    ..Therefore, during vertebrate gastrulation, a single gradient of Bmp activity, which specifies cell fates, also regulates the morphogenetic process of convergent extension...
  29. ncbi request reprint Analysis of cell movements in zebrafish embryos: morphometrics and measuring movement of labeled cell populations in vivo
    Diane S Sepich
    Department of Biological Sciences, Vanderbilt University, Nashcille, TN, USA
    Methods Mol Biol 294:211-33. 2005
    ..We provide a method for quantitative assessment of the movements of cell populations in vivo, and a method for determining whether cell fate and/or movement are disturbed...
  30. pmc Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin
    Seok Hyung Kim
    Vanderbilt University, Department of Biological Sciences, Nashville, TN 37232, USA
    Dis Model Mech 4:255-67. 2011
    ..The finding of a non-cell-autonomous function of mutant cells might help explain the formation of brain hamartomas and cortical malformations in human TSC...
  31. pmc Radar breaks the fog: insights into dorsoventral patterning in zebrafish
    Thomas P Wilm
    Vanderbilt University, VU Station B 351634, Nashville, TN 37235 1634, USA
    Proc Natl Acad Sci U S A 100:4363-5. 2003
  32. pmc Cooperation of polarized cell intercalations drives convergence and extension of presomitic mesoderm during zebrafish gastrulation
    Chunyue Yin
    Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA
    J Cell Biol 180:221-32. 2008
    ....
  33. pmc Phospholipase D1 is required for angiogenesis of intersegmental blood vessels in zebrafish
    Xin Xin I Zeng
    Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA
    Dev Biol 328:363-76. 2009
    ..These results provide the first evidence that function of Pld1 in the developing notochord is essential for vascular development in vertebrates...
  34. pmc Zebrafish Naked1 and Naked2 antagonize both canonical and non-canonical Wnt signaling
    Terence J Van Raay
    Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37235, USA
    Dev Biol 309:151-68. 2007
    ..Finally, reducing Nkd1 function in slb mutants suppressed the axial mesendoderm C&E defect. These data indicate that zebrafish Nkd1 and Nkd2 function to limit both canonical and non-canonical Wnt signaling...
  35. ncbi request reprint Developmentally regulated expression of two members of the Nrarp family in zebrafish
    Jolanta M Topczewska
    Department of Cell Biology and Howard Hughes Medical Institute, Vanderbilt Medical Center, Nashville, TN 37232 2175, USA
    Gene Expr Patterns 3:169-71. 2003
    ..Zebrafish nrarp-a and-b encode small proteins with two ankyrin repeat domains. Here, we report the expression patterns of both genes in normal and mutant embryos...
  36. ncbi request reprint Cellular and genetic mechanisms of convergence and extension
    Lilianna Solnica-Krezel
    Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA
    Results Probl Cell Differ 40:136-65. 2002
  37. pmc Dispatched Homolog 2 is targeted by miR-214 through a combination of three weak microRNA recognition sites
    Nan Li
    Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA
    Nucleic Acids Res 36:4277-85. 2008
    ..This finding underscores the challenge that prediction algorithms face and emphasizes the need to experimentally validate predicted MREs...
  38. ncbi request reprint Fishing for prostanoids: deciphering the developmental functions of cyclooxygenase-derived prostaglandins
    Yong I Cha
    Department of Medicine and Cancer Biology, Cell and Developmental Biology, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN 37232 2279, USA
    Dev Biol 289:263-72. 2006
    ....
  39. pmc Regulation of convergence and extension movements during vertebrate gastrulation by the Wnt/PCP pathway
    Isabelle Roszko
    Vanderbilt University, Department of Biological Sciences, VU Station B 351634, Nashville, TN 37235 1634, USA
    Semin Cell Dev Biol 20:986-97. 2009
    ..We also discuss findings on the molecular regulation and the interaction of the Wnt/PCP pathway with other signaling pathways during gastrulation movements...
  40. ncbi request reprint The Bmp gradient of the zebrafish gastrula guides migrating lateral cells by regulating cell-cell adhesion
    Sophia von der Hardt
    Max Planck Institute of Immunobiology, D 79108 Freiburg, Germany
    Curr Biol 17:475-87. 2007
    ....
  41. pmc Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development
    Oleg V Lagutin
    Department of Genetics, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
    Genes Dev 17:368-79. 2003
    ..Furthermore, these results support the hypothesis that a Wnt signal gradient specifies posterior fates in the anterior neural plate...
  42. ncbi request reprint Migration of zebrafish primordial germ cells: a role for myosin contraction and cytoplasmic flow
    Heiko Blaser
    Germ Cell Development, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Gottingen, Germany
    Dev Cell 11:613-27. 2006
    ..The biased formation of new protrusions in a particular region of the cell in response to SDF-1 defines the leading edge and the direction of cell migration...
  43. ncbi request reprint Inhibition of neurogenesis at the zebrafish midbrain-hindbrain boundary by the combined and dose-dependent activity of a new hairy/E(spl) gene pair
    Jovica Ninkovic
    Zebrafish Neurogenetics Junior Research Group, Institute of Virology, Technical University Munich, Trogerstrasse 4b, D 81675 Munich, Germany
    Development 132:75-88. 2005
    ..We propose a molecular mechanism for this process where the global 'Him+Her5' activity inhibits ngn1 expression in a dose-dependent manner and through different sensitivity thresholds along the medio-lateral axis of the neural plate...
  44. pmc Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly
    Xin Geng
    Department of Genetics and Tumor Cell Biology, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Dev Cell 15:236-47. 2008
    ..These results identify Six3 as a direct regulator of Shh expression and reveal a crossregulatory loop between Shh and Six3 in the ventral forebrain...
  45. ncbi request reprint Atp7a determines a hierarchy of copper metabolism essential for notochord development
    Bryce A Mendelsohn
    Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Cell Metab 4:155-62. 2006
    ..Our data provide insight into the developmental pathophysiology of copper metabolism and suggest that suboptimal copper metabolism may contribute to birth defects...
  46. pmc Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function
    David A Prober
    Department of Molecular and Cellular Biology, Center for Brain Science, Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts 02138, USA
    J Neurosci 28:10102-10. 2008
    ....

Research Grants22

  1. GENETIC ANALYSIS OF CONVERGENT EXTENSION IN ZEBRAFISH
    Lilianna Solnica Krezel; Fiscal Year: 2007
    ..Our work will further elucidate the mechanisms whereby non-canonical Wnt signaling regulates invasive cell behaviors in the context of a developing organism, and will identify additional components of this important pathway. ..
  2. G alpha 12/13 Signaling in Zebrafish Embryogenesis
    Lilianna Solnica Krezel; Fiscal Year: 2007
    ..Given high evolutionary conservation of Ga12/13 and PDZ RhoGEF, our studies will provide new insights into genetic basis of birth defects and tumorigenesis. ..
  3. 2nd Strategic Conference of Zebrafish Investigators
    Lilianna Solnica Krezel; Fiscal Year: 2007
    ..In the process of conference organization, selection of the participants, and throughout the conference, the organizers will encourage participation by women, underrepresented minorities, and persons with disabilities. ..
  4. GENETIC ANALYSIS OF CONVERGENT EXTENSION IN ZEBRAFISH
    Lilianna Solnica Krezel; Fiscal Year: 2009
    ..abstract_text> ..
  5. GENETIC ANALYSIS OF CONVERGENT EXTENSION IN ZEBRAFISH
    Lilianna Solnica Krezel; Fiscal Year: 2005
    ..The proposed experiments will provide insights into the vertebrate Wnt planar cell polarity pathway and the mechanisms of cell polarization during vertebrate gastrulation and morphogenesis. ..
  6. GENETIC ANALYSIS OF CONVERGENT EXTENSION IN ZEBRAFISH
    Lilianna Solnica Krezel; Fiscal Year: 2000
    ..In a larger perspective, analysis of these mutants will help to explain the genetic basis for disorders in very early stages of human development, miscarriages and birth defects. ..
  7. GENETIC REGULATION OF SOMITE MORPHOGENESIS IN ZEBRAFISH
    Lilianna Solnica Krezel; Fiscal Year: 2004
    ....
  8. G alpha 12/13 Signaling in Zebrafish Embryogenesis
    Lilianna Solnica Krezel; Fiscal Year: 2009
    ..Given high evolutionary conservation of Ga12/13 and PDZ RhoGEF, our studies will provide new insights into genetic basis of birth defects and tumorigenesis. ..