Joseph A Smith

..RALP provides outcomes at least comparable, and, in some measures, superior to open surgery. Refinements of instrumentation may provide even better results in the future...

..However, the most important outcome measures are tumor control, continence, and sexual potency. The outstanding visibility and precision afforded by the robotic approach may offer advantages in each of these areas...

..To review the role of radical prostatectomy in the management of patients with low risk carcinoma of the prostate...

..We determined whether there is a difference in survival parameters in patients with pathological T2a vs T2b urothelial carcinoma of the bladder...

..To determine whether robotic-assisted laparoscopic radical prostatectomy (RALP) is associated with a lower transfusion rate than radical retropubic prostatectomy (RRP)...

..We compared biochemical recurrence-free survival of patients who underwent radical retropubic prostatectomy vs robot assisted laparoscopic prostatectomy in concurrent series at a single institution...

..We evaluated the incidence and location of positive surgical margins in 200 sequential robotic assisted laparoscopic radical prostatectomy and 200 sequential open radical retropubic prostatectomy cases...

..We determined the percentage of men in a large prostate cancer registry who met criteria predictive of latent prostate cancer. We also assessed the percentage of men meeting these criteria who chose surveillance...

..The role of malnutrition has not been well studied in patients undergoing surgery for renal cell carcinoma (RCC)...

..Our aim in this study was to (a) evaluate tumor volume as an independent predictor of adverse pathologic outcomes and BCR and (b) determine the effect of two different methods of tumor volume estimation...

..To evaluate the outcomes based on gland size between robotically assisted radical prostatectomy (RALP) and open RP (RRP), as larger prostates might increase the difficulty of RP...

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..We determined whether prostate size predicts Gleason score upgrading in patients with low risk prostate cancer...

..To examine the impact of urinary collecting system invasion (UCSI) on survival in patients with pathologic stage T3 renal cell carcinoma (RCC)...

..We characterized the prognostic significance of hydronephrosis, and its relationship to cancer stage and outcome. We also evaluated concordance between the side of identifiable hydronephrosis and concomitant pelvic lymph node metastasis...

..We evaluated whether a positive surgical margin at the apex confers a different likelihood of biochemical recurrence than at other sites...

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..The LRN technique has a 21% lower total cost than both HALRN and ORN...

..Considerable controversy remains regarding the correlation between node count and survival, and most prior analyses have not accounted for both patient and provider factors...

..We sought to determine the impact of radical nephrectomy case volume, hospital size, and geographic region on immediate surgical outcomes for patients undergoing radical nephrectomy in academic centers across the country...

..While surgery provides modest disease-free survival, most patients should be offered immunotherapy, particularly those with advanced stage, grade, nodal involvement or metastases...

..We compared whole mount and systematic sampling for detecting pathological outcomes, and compared the prognostic value of pathological findings across pathological methods...

..To determine the impact of hospital variables on immediate surgical outcomes for patients treated with radical prostatectomy (RP) in academic centres...

..In a large series of patients they found that residual tumour after initial resection was commoner than might be expected, and that the second resection indicated the way to earlier radical treatment and a better prognosis...

..Despite these modifications in the treatment of patients having open RRP there was no increase in morbidity or compromise in patient outcome. Indeed, this study shows the feasibility and safety of a 1-day length of stay for open RRP...

..To examine the risk factors for urothelial carcinoma (UC) involvement of the prostate in patients undergoing radical cystoprostatectomy (RCP) for bladder cancer, as such involvement has both prognostic and therapeutic implications...

..Overall disease recurrence was relatively high in patients with high risk pathological features but urethral recurrence in this group with orthotopic urinary diversion remained low...

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..The low rate of complications combined with the advantages of laparoscopic surgery favor a laparoscopic approach for the majority of patients with stage T1 and T2 tumors...

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..This study sought to determine the incidence of the various histologic subtypes of renal cortical tumors according to size in a contemporary series of surgically treated patients...

..The acceptable rate of early morbidity in this series in a 5-year period validates its use in patients undergoing radical cystectomy...

..We analyzed the predictors of early (30 days or less), late (31 to 90 days) and cumulative 90-day hospital readmissions, as well as morbidity and mortality rates...

..We report the results of a new questionnaire designed specifically to measure HRQOL in these patients...

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..To evaluate the impact of prostatic urothelial carcinoma (PUC) on survival of patients with bladder cancer undergoing radical cystoprostatectomy (RCP)...

..We evaluated whether the 2002 TNM substages of pathological T2 prostate cancer predict intermediate term biochemical recurrence-free survival...

..We describe hospital discharge status in patients after radical cystectomy for bladder cancer. We determined factors affecting discharge status...

..We evaluated the effect of preoperative nutritional deficiency on perioperative mortality and overall survival in patients undergoing radical cystectomy for bladder cancer...

..We examine the prevalence of postoperative voiding complications in women who underwent orthotopic neobladder diversion...

..e. solitary kidney, bilateral renal masses, and multifocal tumours) or have used maximal tumour diameter (i.e. tumour size) alone in their assessment of the clinical variables associated with PN use...

..We examined the hospital characteristics associated with outcomes after radical cystectomy in a cohort study using results from a single, high volume academic institution as well as a nationwide data set of academic institutions...

..We examined differences in length of stay between a prospectively evaluated cohort of patients who underwent radical retropubic prostatectomy and robot assisted laparoscopic prostatectomy...

..We sought to better identify patients at substantial risk for postoperative mortality...

..We reviewed our patients with pathologic T3b renal cell carcinoma (RCC) to determine which factors influenced survival in this high risk patient group...

..These acceptable risks as well as the potential benefits should be discussed with patients with nonmuscle invasive bladder cancer at high risk for disease progression...

..We determined whether the interval between diagnosis of muscle invasion and definitive radical cystectomy influenced pathological staging outcome...

..We also describe the association between statin use and prostate cancer and high-grade prostatic intraepithelial neoplasia (PIN) before and after controlling for prostate cancer screening indices associated with statin use...

..We report survival and recurrence outcomes in all patients undergoing radical or partial nephrectomy for renal cell carcinoma, as related to surgical waiting time...

..We studied the relationship between surgeon and hospital volume, and overall mortality after radical cystectomy...

..Using trajectory clustering analysis we identified predictors of post-prostatectomy urinary incontinence recovery in unique patient groups...

..However, the prognostic significance of CPI as defined appears similar to that of pT3a with positive margins...

..Patients with CIS-only on clinical and pathological staging have an excellent disease-free survival with radical cystectomy even with the presence of multifocal disease...

..The impact on functional outcomes and cancer control also require additional study...

..Therapy (case series) Level of Evidence 4...

..Outcomes other than pain will ultimately determine the role of laparoscopic radical prostatectomy and RALP...

..Prospective evaluation is needed to assess the long-term impact on functional outcomes and cancer control...

..The lack of a statistically significant difference in blood transfusion was partially attributable to the low transfusion rate in both groups in this series...

..We analyzed patient characteristics and practice patterns at our institution with time, and identified current patterns and factors contributing to the choice of urinary diversion...

..In the current study, the authors evaluated the safety and efficacy of a pathway transitioning from a 3-day to a 2-day LOS...

..We evaluated the use of %fPSA to predict CaP pathology including percent of tumor involvement in the radical prostatectomy (RP) specimen...

..Inflammation has emerged as a mediator of prostate cancer metastatic progression. We hypothesized that chemokines can be biomarkers for distinguishing patients with high risk for biochemical recurrence of prostate cancer...

..09). CONCLUSIONS: Our collaborative clinical care pathway safely and efficiently outlines routine postoperative care and significantly decreased hospital stay...

..01). In conclusion, prostate volume acts as a modifier, and BMI and WHR are significantly associated with prostate cancer or PIN, respectively, in the absence of biopsy sampling error derived from obesity-related prostate enlargement...

..We reviewed our contemporary radical cystectomy series to evaluate perioperative outcome measures which could be affected by surgical approach for the purpose of establishing contemporary benchmarks for future comparisons...

..Surgical experience is important for the mastery of operative procedures. We evaluated the current United States urological surgical resident training in performing retroperitoneal lymph node dissection...

..Postoperative ileus is the most common cause of prolonged hospitalization. Age, gender, American Society of Anesthesiologists score, urinary diversion type and pathological stage did not correlate with increased hospital stay...

..If such transition zone tumors prove to be biologically distinct, improved strategies to identify these lesions preoperatively may result in more conservative treatment recommendations...

..In addition, these data imply that a prior history of abdominal and/or pelvic radiation should not serve as the sole determining factor in the selection of bowel segment utilized during urinary diversion...

..The patient was disease free at last follow-up 4 years after surgery...

..We evaluated the impact of body mass index (BMI), an objective measure of obesity, on operative and perioperative outcomes in patients undergoing radical cystectomy...

..Reluctance to offer timely, aggressive local therapy may compromise ultimate survival, even amongst high operative risk, elderly patients...

..To identify supplement use among patients diagnosed with testicular cancer. The incidence of testicular cancer has increased, as has supplement use, including those designed specifically for exercise performance enhancement...

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..Although significant progress has been made in understanding and treating hormone-refractory prostate carcinoma, earlier interventions would be ideal and better therapeutic approaches to prolong survival are necessary...

..Accordingly, resident training should provide the framework for mastery of complex operations. We evaluated the current urological residency experience in performing adult urinary diversion...

..To assess gastrointestinal (GI) and genitourinary (GU) toxicity in patients treated with salvage radiotherapy (SRT) at doses of 70.2 Gy after radical retropubic prostatectomy (RRP)...

..A prospective longitudinal study of health related quality of life after adjusting for differences in age among patients undergoing urinary diversion is currently underway to extend further these observations...

..We assessed recent blood loss and transfusion requirements in contemporary patients undergoing RRP and examined the possible predictive impact of preoperative variables...

..This policy has been safe and efficacious. We believe that admission to the intensive care unit should only be done in select cases...

..Therefore, orthotopic reconstruction can be offered to patients who want to avoid an abdominal stoma even in the face of significant co-morbid conditions...

..These significant advantages combined with its relative safety make it an attractive surgical option and argue in favor of continued strategic attempts to decrease blood loss during radical cystectomy...

..Our aim was to determine the incidence of symptomatic DVT and PE and the risk factors for these complications...

..Whether these results are a consequence of an effective unilateral nerve-sparing dissection or the nerve grafting itself is uncertain...