Xiao Shu

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. pmc Exome sequencing generates high quality data in non-target regions
    Yan Guo
    Center for Quantitative Sciences, Vanderbilt Ingram Cancer Center, Nashville, TN, USA
    BMC Genomics 13:194. 2012
  2. pmc Polycyclic aromatic hydrocarbons: determinants of urinary 1-hydroxypyrene glucuronide concentration and risk of colorectal cancer in the Shanghai Women's Health Study
    Jonathan N Hofmann
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    BMC Cancer 13:282. 2013
  3. pmc Identification of new genetic risk variants for type 2 diabetes
    Xiao Ou Shu
    Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    PLoS Genet 6:e1001127. 2010
  4. pmc Polymorphisms in inflammation pathway genes and endometrial cancer risk
    Ryan J Delahanty
    Division of Epidemiology, Department of Medicineand Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA
    Cancer Epidemiol Biomarkers Prev 22:216-23. 2013
  5. pmc Calcium intake and lung cancer risk among female nonsmokers: a report from the Shanghai Women's Health Study
    Yumie Takata
    Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA
    Cancer Epidemiol Biomarkers Prev 22:50-7. 2013
  6. pmc Genome-wide association study identifies a possible susceptibility locus for endometrial cancer
    Jirong Long
    Department of Medicine, Vanderbilt University Schoolof Medicine, Nashville, TN, USA
    Cancer Epidemiol Biomarkers Prev 21:980-7. 2012
  7. pmc Novel genetic markers of breast cancer survival identified by a genome-wide association study
    Xiao Ou Shu
    Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA
    Cancer Res 72:1182-9. 2012
  8. pmc Duration of breast-feeding and the incidence of type 2 diabetes mellitus in the Shanghai Women's Health Study
    R Villegas
    Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Department of Medicine, Vanderbilt University Medical Center, 2525 West End Avenue, Suite 600, Nashville, TN 37232 1738, USA
    Diabetologia 51:258-66. 2008
  9. pmc IGFBP3 mRNA expression in benign and malignant breast tumors
    Zefang Ren
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University, S 1121 MCN, 1161 21st Ave, S, Nashville, TN 37232 2587, USA
    Breast Cancer Res 9:R2. 2007
  10. pmc Genetic polymorphisms in the matrix metalloproteinase 12 gene (MMP12) and breast cancer risk and survival: the Shanghai Breast Cancer Study
    Aesun Shin
    Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA
    Breast Cancer Res 7:R506-12. 2005

Detail Information

Publications144 found, 100 shown here

  1. pmc Exome sequencing generates high quality data in non-target regions
    Yan Guo
    Center for Quantitative Sciences, Vanderbilt Ingram Cancer Center, Nashville, TN, USA
    BMC Genomics 13:194. 2012
    ..A significant amount of DNA fragments from the capture process fall outside target regions, and sequence data for positions outside target regions have been mostly ignored after alignment...
  2. pmc Polycyclic aromatic hydrocarbons: determinants of urinary 1-hydroxypyrene glucuronide concentration and risk of colorectal cancer in the Shanghai Women's Health Study
    Jonathan N Hofmann
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    BMC Cancer 13:282. 2013
    ....
  3. pmc Identification of new genetic risk variants for type 2 diabetes
    Xiao Ou Shu
    Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    PLoS Genet 6:e1001127. 2010
    ..Our study provides strong evidence for a novel T2D susceptibility locus at 13q31.1 and the presence of new independent risk variants near regions (10p13 and 15q22.2) reported by previous GWAS...
  4. pmc Polymorphisms in inflammation pathway genes and endometrial cancer risk
    Ryan J Delahanty
    Division of Epidemiology, Department of Medicineand Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA
    Cancer Epidemiol Biomarkers Prev 22:216-23. 2013
    ..Experimental and epidemiologic evidence have suggested that chronic inflammation may play a critical role in endometrial carcinogenesis...
  5. pmc Calcium intake and lung cancer risk among female nonsmokers: a report from the Shanghai Women's Health Study
    Yumie Takata
    Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA
    Cancer Epidemiol Biomarkers Prev 22:50-7. 2013
    ..Calcium has been implicated in carcinogenesis and linked to the risk of several cancers in epidemiologic studies; however, few studies have investigated the association of calcium intake with lung cancer risk, particularly among nonsmokers...
  6. pmc Genome-wide association study identifies a possible susceptibility locus for endometrial cancer
    Jirong Long
    Department of Medicine, Vanderbilt University Schoolof Medicine, Nashville, TN, USA
    Cancer Epidemiol Biomarkers Prev 21:980-7. 2012
    ..Genome-wide association studies (GWAS) have identified more than 100 genetic loci for various cancers. However, only one is for endometrial cancer...
  7. pmc Novel genetic markers of breast cancer survival identified by a genome-wide association study
    Xiao Ou Shu
    Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA
    Cancer Res 72:1182-9. 2012
    ..39 × 10(-7)). Similar associations were observed for these two SNPs with breast cancer-specific mortality. This study provides strong evidence suggesting that the RAD51L1 gene and a chromosome 16 locus influence breast cancer prognosis...
  8. pmc Duration of breast-feeding and the incidence of type 2 diabetes mellitus in the Shanghai Women's Health Study
    R Villegas
    Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Department of Medicine, Vanderbilt University Medical Center, 2525 West End Avenue, Suite 600, Nashville, TN 37232 1738, USA
    Diabetologia 51:258-66. 2008
    ..The aim of this study was to examine the association between lifetime breast-feeding and the incidence of type 2 diabetes mellitus in a large population-based cohort study of middle-aged women...
  9. pmc IGFBP3 mRNA expression in benign and malignant breast tumors
    Zefang Ren
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University, S 1121 MCN, 1161 21st Ave, S, Nashville, TN 37232 2587, USA
    Breast Cancer Res 9:R2. 2007
    ..Emerging evidence over the past few years suggests that IGFBP-3 may act directly on mammary epithelial cells...
  10. pmc Genetic polymorphisms in the matrix metalloproteinase 12 gene (MMP12) and breast cancer risk and survival: the Shanghai Breast Cancer Study
    Aesun Shin
    Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA
    Breast Cancer Res 7:R506-12. 2005
    ....
  11. pmc Patterns and correlates of physical activity: a cross-sectional study in urban Chinese women
    Adriana L Jurj
    Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37203, USA
    BMC Public Health 7:213. 2007
    ..The purpose of this study was to investigate the patterns and correlates of physical activity in middle-aged and elderly women from urban Shanghai...
  12. pmc Concordance of self-reported and medical chart information on cancer diagnosis and treatment
    Vinay Gupta
    Department of Cancer Control and Prevention, Shanghai Municipal Center for Disease Control and Prevention, 1380 Zhongshan Road West, Shanghai 200336, China
    BMC Med Res Methodol 11:72. 2011
    ..Self-reported information is an important tool for collecting clinical information for epidemiologic studies and in clinical settings where electronic medical records are not employed and shared...
  13. pmc Distinct distribution and prognostic significance of molecular subtypes of breast cancer in Chinese women: a population-based cohort study
    Yinghao Su
    Department of Medicine, Vanderbilt Epidemiology Center, Nashville, TN 37203 1738, USA
    BMC Cancer 11:292. 2011
    ..Molecular classification of breast cancer is an important prognostic factor. The distribution of molecular subtypes of breast cancer and their prognostic value has not been well documented in Asians...
  14. ncbi request reprint Genetic polymorphisms in the TGF-beta 1 gene and breast cancer survival: a report from the Shanghai Breast Cancer Study
    Xiao Ou Shu
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA
    Cancer Res 64:836-9. 2004
    ..4, 95% confidence interval, 1.0-1.9). Our study suggests that genetic polymorphisms in the TGF-beta1 gene may play a role in breast cancer progression...
  15. pmc Exercise after diagnosis of breast cancer in association with survival
    Xiaoli Chen
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Cancer Prev Res (Phila) 4:1409-18. 2011
    ..An interaction between disease stage and hormone receptor status and total mortality was noted. Our study suggests that exercise after breast cancer diagnosis may improve overall and disease-free survival...
  16. ncbi request reprint Polymorphisms in ER-alpha gene interact with estrogen receptor status in breast cancer survival
    Sonia M Boyapati
    Center for Health Services Research, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Medical Center East, Suite 6000, Nashville, TN 37232 8300, USA
    Clin Cancer Res 11:1093-8. 2005
    ..Polymorphisms in the ER-alpha gene have been reported to be associated with breast cancer risk. However, to our knowledge, no study has been published on the relation between ER-alpha gene polymorphisms and breast cancer survival...
  17. ncbi request reprint Association of cyclin D1 genotype with breast cancer risk and survival
    Xiao Ou Shu
    Department of Medicine, Vanderbilt University Center for Health Services Research, 6th Floor, Medical Center East, Nashville, TN 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 14:91-7. 2005
    ..This study suggests that CCND1 A870G polymorphism may modify the postmenopausal breast cancer risk associated with hormonal exposure and predict survival after breast cancer diagnosis...
  18. ncbi request reprint Validity and reproducibility of the food frequency questionnaire used in the Shanghai Women's Health Study
    X O Shu
    Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt Center for Health Services Research, Vanderbilt University, Nashville, TN 37232 8300, USA
    Eur J Clin Nutr 58:17-23. 2004
    ..These data indicate that the SWHS FFQ can reliably and accurately measure usual intake of major nutrients and food groups among women in Shanghai...
  19. ncbi request reprint Parental exposure to medications and hydrocarbons and ras mutations in children with acute lymphoblastic leukemia: a report from the Children's Oncology Group
    Xiao Ou Shu
    Vanderbilt Ingram Cancer Center and Vanderbilt Center for Health Services Research, Vanderbilt University, Nashville, Tennessee, USA
    Cancer Epidemiol Biomarkers Prev 13:1230-5. 2004
    ..8, 95% CI 1.0-1.3) were associated with N-ras mutations. This study suggests that parental exposure to specific chemicals may be associated with distinct ras mutations in children who develop ALL...
  20. pmc Soy food intake and breast cancer survival
    Xiao Ou Shu
    Department of Medicine, Vanderbilt Epidemiology Center, 2525 West End Ave, Ste 600, Nashville, TN 37203 1738, USA
    JAMA 302:2437-43. 2009
    ..However, the estrogen-like effect of isoflavones and the potential interaction between isoflavones and tamoxifen have led to concern about soy food consumption among breast cancer patients...
  21. ncbi request reprint Cruciferous vegetables, the GSTP1 Ile105Val genetic polymorphism, and breast cancer risk
    Sang Ah Lee
    Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA
    Am J Clin Nutr 87:753-60. 2008
    ..Cruciferous vegetables are the primary source of isothiocyanates and other glucosinolate derivatives that are known to induce phase II detoxifying enzymes, including glutathione S-transferases (GSTs)...
  22. ncbi request reprint Polymorphisms in the CYP19A1 (aromatase) gene and endometrial cancer risk in Chinese women
    Meng Hua Tao
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine and Vanderbilt Ingram Cancer Center, Nashville, Tennessee 37203 1738, USA
    Cancer Epidemiol Biomarkers Prev 16:943-9. 2007
    ..In summary, our data show that polymorphisms in the CYP19A1 gene may contribute to endometrial carcinogenesis...
  23. ncbi request reprint Genetic polymorphisms in the IGFBP3 gene: association with breast cancer risk and blood IGFBP-3 protein levels among Chinese women
    Zefang Ren
    Department of Medicine, Vanderbilt University, Nashville, TN, USA
    Cancer Epidemiol Biomarkers Prev 13:1290-5. 2004
    ..05). These results indicated that IGFBP3 polymorphisms may be associated with the level of blood IGFBP-3 protein and an increased risk of breast cancer...
  24. pmc Energy balance, insulin resistance biomarkers, and breast cancer risk
    Alecia Malin Fair
    Meharry Medical College, School of Medicine, Department of Surgery, 1005 Dr D B Todd Jr Boulevard, Nashville, TN 37208 3599, USA
    Cancer Detect Prev 31:214-9. 2007
    ....
  25. ncbi request reprint Population-based case-control study of VEGF gene polymorphisms and breast cancer risk among Chinese women
    Nobuhiko Kataoka
    Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN, USA
    Cancer Epidemiol Biomarkers Prev 15:1148-52. 2006
    ..67; 95% CI, 0.43-1.04), particularly in premenopausal women (OR, 0.47; 95% CI, 0.27-0.81). Our study suggests that the VEGF C936T polymorphism might be a susceptibility factor for breast cancer among Chinese women...
  26. pmc Association of mitochondrial DNA displacement loop (CA)n dinucleotide repeat polymorphism with breast cancer risk and survival among Chinese women
    Chuanzhong Ye
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine and Vanderbilt Ingram Cancer Center, Nashville, TN 37232 2400, USA
    Cancer Epidemiol Biomarkers Prev 17:2117-22. 2008
    ..62; 95% confidence interval, 1.16-2.26). These results suggest that the mtDNA D-loop (CA)(n) repeat polymorphism may be associated with breast cancer survival. Additional studies with a larger sample size are warranted...
  27. ncbi request reprint Urinary isothiocyanate excretion, brassica consumption, and gene polymorphisms among women living in Shanghai, China
    Jay H Fowke
    Vanderbilt University Medical Center, Nashville, Tennessee 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 12:1536-9. 2003
    ..In conclusion, a single urinary ITC measure, in conjunction with markers of Phase II enzyme activity, provides a complementary measure of habitual Brassica intake among Shanghai women...
  28. ncbi request reprint Association of breast cancer risk with a common functional polymorphism (Asp327Asn) in the sex hormone-binding globulin gene
    Yong Cui
    Vanderbilt University Center for Health Services Research, 6th Floor, Medical Center East, Nashville, TN 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 14:1096-101. 2005
    ..05). This study suggests that the Asn allele in the SHBG gene may be related to a reduced risk of breast cancer among postmenopausal women by increasing their blood SHBG levels...
  29. pmc Dietary patterns and blood pressure among middle-aged and elderly Chinese men in Shanghai
    Sang Ah Lee
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, 2525 West End Avenue, Suite 600, IMPH, Nashville TN 37203 1738, USA
    Br J Nutr 104:265-75. 2010
    ..Results of the present study suggest an important role for diet in the prevention of hypertension...
  30. ncbi request reprint Association of endometrial cancer risk with a functional polymorphism (Asp(327)Asn) in the sex hormone-binding globulin gene
    Nobuhiko Kataoka
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, Tennessee, USA
    Cancer 109:1296-302. 2007
    ....
  31. ncbi request reprint MTHFR polymorphisms, dietary folate intake, and breast cancer risk: results from the Shanghai Breast Cancer Study
    Martha J Shrubsole
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 13:190-6. 2004
    ..Results of this study suggest that the MTHFR C677T polymorphisms may modify the association between dietary folate intake and breast cancer risk...
  32. pmc Evaluation of genetic susceptibility loci for obesity in Chinese women
    Jiajun Shi
    Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Am J Epidemiol 172:244-54. 2010
    ..Results from this study extend some previous GWA findings to Chinese women and show the need for additional studies to identify susceptibility loci in Chinese and other Asian populations...
  33. ncbi request reprint Correlates of high serum C-reactive protein levels in a socioeconomically disadvantaged population
    Xianglan Zhang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA
    Dis Markers 24:351-9. 2008
    ..Moreover, inflammatory response to obesity differed by race and sex, which may contribute to CVD disparities...
  34. ncbi request reprint Two-stage case-control study of common ATM gene variants in relation to breast cancer risk
    Chuanzhong Ye
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37232 2587, USA
    Breast Cancer Res Treat 106:121-6. 2007
    ....
  35. ncbi request reprint Prospective study of dietary carbohydrates, glycemic index, glycemic load, and incidence of type 2 diabetes mellitus in middle-aged Chinese women
    Raquel Villegas
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, 2525 West End Ave, Ste 600, Nashville, TN 37203 1738, USA
    Arch Intern Med 167:2310-6. 2007
    ..Much uncertainty exists about the role of dietary glycemic index and glycemic load in the development of type 2 diabetes mellitus, especially in populations that traditionally subsist on a diet high in carbohydrates...
  36. ncbi request reprint Cytochrome P450 1B1 and catechol-O-methyltransferase genetic polymorphisms and breast cancer risk in Chinese women: results from the shanghai breast cancer study and a meta-analysis
    Wanqing Wen
    Department of Medicine, Vanderbilt Ingram Cancer Center, Center for Health Service Research, Vanderbilt University School of Medicine, Nashville, TN, USA
    Cancer Epidemiol Biomarkers Prev 14:329-35. 2005
    ..The results from this study were consistent with those from most previous studies, indicating no major associations of breast cancer risk with CYP1B1 and COMT polymorphisms...
  37. pmc Legume and soy food intake and the incidence of type 2 diabetes in the Shanghai Women's Health Study
    Raquel Villegas
    Department of Medicine, Vanderbilt Epidemiology Center, Nashville, TN 37203 1738, USA
    Am J Clin Nutr 87:162-7. 2008
    ..It has been postulated that a diet high in legumes may be beneficial for the prevention of type 2 diabetes mellitus (type 2 DM). However, data linking type 2 DM risk and legume intake are limited...
  38. ncbi request reprint Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 (UGT1A1) and risk of breast cancer
    Olufemi J Adegoke
    Department of Surgery, School of Medicine, Meharry Medical College, Vanderbilt University, Nashville, TN 37208, USA
    Breast Cancer Res Treat 85:239-45. 2004
    ..No significant associations were observed with *28 allele and breast cancer risk by estrogen receptor/progesterone receptor status...
  39. ncbi request reprint Genetic polymorphisms of the CYP19A1 gene and breast cancer survival
    Ji Rong Long
    Department of Medicine, Center for Epidemiologic Research, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 2587, USA
    Cancer Epidemiol Biomarkers Prev 15:2115-22. 2006
    ..2-4.1) for overall survival and 2.1 (95% CI, 1.1-3.9) for disease-free survival, compared with those carrying the Arg (C) allele. These results suggest that polymorphisms in the CYP19A1 gene may have effects on breast cancer prognosis...
  40. ncbi request reprint Population-based case-control study of AhR (aryl hydrocarbon receptor) and CYP1A2 polymorphisms and breast cancer risk
    Ji Rong Long
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, 1161 21st Avenue South, Nashville, TN 37232, USA
    Pharmacogenet Genomics 16:237-43. 2006
    ....
  41. ncbi request reprint Nutrient intake among Chinese women living in Shanghai, China
    Zhi Chen
    Department of Medicine, Center for Health Services Research and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232 8300, USA
    Br J Nutr 96:393-9. 2006
    ....
  42. pmc Haplotype analysis of CYP11A1 identifies promoter variants associated with breast cancer risk
    Brian L Yaspan
    Department of Cancer Biology, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, TN 37232 0275, USA
    Cancer Res 67:5673-82. 2007
    ..94 (95% CI, 1.22-7.12), test for trend, P = 5.0e-5. Among genes controlling endogenous estrogen metabolism, CYP11A1 harbors common variants that may influence expression to significantly modify risk of breast cancer...
  43. doi request reprint UGT1A1 genetic polymorphisms, endogenous estrogen exposure, soy food intake, and endometrial cancer risk
    Sandra L Deming
    Vanderbilt Epidemiology Center, Department of Medicine and Vanderbilt Ingram Cancer Center, Nashville, TN 37203 1738, USA
    Cancer Epidemiol Biomarkers Prev 17:563-70. 2008
    ....
  44. ncbi request reprint Genetic polymorphisms in estrogen-metabolizing genes and breast cancer survival
    Ji Rong Long
    Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, 1161 21st Avenue South, S 1121 Medical Center North, Nashville, TN 37232, USA
    Pharmacogenet Genomics 17:331-8. 2007
    ..The objective of the study is to investigate associations of breast cancer survival with genetic polymorphisms in several genes involved in estrogen metabolism (CYP1A1, CYP1A2, CYP1B1, COMT, and AhR)...
  45. ncbi request reprint Genetic polymorphisms of the transforming growth factor-beta1 gene and breast cancer risk: a possible dual role at different cancer stages
    Aesun Shin
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 14:1567-70. 2005
    ....
  46. pmc Prevalence of obesity and correlations with lifestyle and dietary factors in Chinese men
    Sang Ah Lee
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, Tennessee, USA
    Obesity (Silver Spring) 16:1440-7. 2008
    ..To estimate the age-adjusted prevalence of general and centralized obesity among Chinese men living in urban Shanghai...
  47. pmc Dietary and lifestyle predictors of age at natural menopause and reproductive span in the Shanghai Women's Health Study
    Tsogzolmaa Dorjgochoo
    Department of Medicine, Vanderbilt Epidemiology Center, School of Medicine, Vanderbilt University and Vanderbilt Ingram Cancer Center, Nashville, TN 37203 1738, USA
    Menopause 15:924-33. 2008
    ..We evaluated the impact of dietary, lifestyle and reproductive factors on age at natural menopause and reproductive span in Chinese women...
  48. pmc Vegetable but not fruit consumption reduces the risk of type 2 diabetes in Chinese women
    Raquel Villegas
    Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Nashville, TN 37203 1738, USA
    J Nutr 138:574-80. 2008
    ..Fruit intake was not associated with the incidence of diabetes in this population. Our data suggest that vegetable consumption may protect against the development of T2D...
  49. pmc Adolescent and adult soy food intake and breast cancer risk: results from the Shanghai Women's Health Study
    Sang Ah Lee
    Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Am J Clin Nutr 89:1920-6. 2009
    ..Soy food is a rich source of isoflavones--a class of phytoestrogens that has both antiestrogenic and anticarcinogenic properties...
  50. ncbi request reprint Association of genetic polymorphisms in the VEGF gene with breast cancer survival
    Hua Lu
    Department of Medicine, Center for Health Services Research, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 8300, USA
    Cancer Res 65:5015-9. 2005
    ..1; 95% CI, -0.9 to 4.7). The C+936T polymorphism alone was not related to overall or disease-free survival. This study suggests that VEGF polymorphisms may be a significant genetic marker for breast cancer prognosis...
  51. ncbi request reprint Polymorphisms in CYP1A1 and breast carcinoma risk in a population-based case-control study of Chinese women
    Sonia M Boyapati
    Department of Medicine, Center for Health Services Research, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Cancer 103:2228-35. 2005
    ..Cytochrome P450 1A1 (CYP1A1) is involved in the 2-hydroxylation of estrogen, the hormone that plays a critical role in the etiology of breast carcinoma...
  52. pmc Matrix metalloproteinase-2 polymorphisms and breast cancer susceptibility
    Alicia Beeghly-Fadiel
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203 1738, USA
    Cancer Epidemiol Biomarkers Prev 18:1770-6. 2009
    ..4; 95% CI, 0.9-2.4). Together, these findings support a role for MMP-2 genetic variation in breast cancer susceptibility...
  53. pmc Mutations in the mitochondrial DNA D-loop region and breast cancer risk
    Chuanzhong Ye
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, B 2104, Medical Center North, 1161 21st Avenue South, Nashville, TN 37232 2400, USA
    Breast Cancer Res Treat 119:431-6. 2010
    ..3%) than in BBD patients (15.3%) (P = 0.05) and more frequently in proliferative BBD (13.0%) than in non-proliferative BBD (7.1%). Our data suggest that somatic MnlI site mutations may play a role in the pathogenesis of breast cancer...
  54. pmc Genetic polymorphisms in the MMP-7 gene and breast cancer survival
    Alicia Beeghly-Fadiel
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Int J Cancer 124:208-14. 2009
    ..9) and TT (OS HR: 0.3, 95% CI: 0.1-0.8) fared better than patients with AA (p-value for trend: 0.001). Thus, common MMP-7 genetic polymorphisms were found to be significant determinants of survival among Chinese women with breast cancer...
  55. ncbi request reprint Association of passive smoking by husbands with prevalence of stroke among Chinese women nonsmokers
    Xianglan Zhang
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA
    Am J Epidemiol 161:213-8. 2005
    ..The authors found that women nonsmokers who lived with husbands who smoked had an elevated prevalence of stroke, and prevalence increased with increasing intensity and duration of husbands' smoking...
  56. ncbi request reprint Functional plasminogen activator inhibitor-1 gene variants and breast cancer survival
    Xianglan Zhang
    Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 8300, USA
    Clin Cancer Res 12:6037-42. 2006
    ..We evaluated the association between PAI-1 4G/5G polymorphism and breast cancer survival in a population-based cohort of breast cancer patients...
  57. pmc Menopausal symptoms among breast cancer patients 6 months after diagnosis: a report from the Shanghai Breast Cancer Survival Study
    Tsogzolmaa Dorjgochoo
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Menopause 16:1205-12. 2009
    ..The aim of this study was to estimate the prevalence of menopausal symptoms in relation to treatment modalities in Asian women treated for breast cancer...
  58. pmc Exercise, tea consumption, and depression among breast cancer survivors
    Xiaoli Chen
    Vanderbilt Epidemiology Center, 2525 West End Ave, Suite 600, Nashville, TN 37203 1738, USA
    J Clin Oncol 28:991-8. 2010
    ..84). No associations were found for dietary intake or supplement use with depression. CONCLUSION Regular exercise participation and tea consumption may play an important role in the prevention of depression among breast cancer survivors...
  59. ncbi request reprint Validity and reproducibility of the food-frequency questionnaire used in the Shanghai men's health study
    Raquel Villegas
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Medical Center East, Suite 6000, 1215 21st Avenue South, Nashville, TN 37232 8300, USA
    Br J Nutr 97:993-1000. 2007
    ..8 and 49.2%, while misclassification to opposite quartiles was between 1.5 and 6.2%. These data indicate that the SMHS FFQ can reasonably categorise usual intake of nutrients and food groups among men living in urban Shanghai...
  60. pmc Obesity and weight change in relation to breast cancer survival
    Xiaoli Chen
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, 2525 West End Avenue, Suite 600, Nashville, TN 37203 1738, USA
    Breast Cancer Res Treat 122:823-33. 2010
    ..Our study suggests that obesity and weight change after diagnosis are inversely associated with breast cancer prognosis. Weight control is important among women with breast cancer...
  61. pmc Polymorphisms in tissue inhibitors of metalloproteinases-2 and -3 and breast cancer susceptibility and survival
    Neeraja B Peterson
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Int J Cancer 125:844-50. 2009
    ..Genetic variation in the TIMP-2 and TIMP-3 genes may contribute to individual differences in breast cancer susceptibility and survival...
  62. pmc Interaction of soy and 17beta-HSD1 gene polymorphisms in the risk of endometrial cancer
    Qi Dai
    Department of Medicine and Vanderbilt Ingram Cancer Center, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA
    Pharmacogenet Genomics 17:161-7. 2007
    ..In-vitro studies have found that soy isoflavones can inhibit the activity of 17beta-hydroxysteroid dehydrogenase type I, a key enzyme in catalyzing estrone (E1), to the biologically more active estradiol (E2)...
  63. pmc Energy balance and breast cancer risk
    Alecia Malin
    Department of Surgery, Meharry Medical College, 1005 Dr D B Todd Boulevard, Nashville, Tennessee 37208, USA
    Cancer Epidemiol Biomarkers Prev 14:1496-501. 2005
    ..74; 95% confidence interval, 2.05-12.20). Our study suggests that promotion of behavior patterns that optimize energy balance (weight control and increasing physical activity) may be a viable option for breast cancer prevention...
  64. ncbi request reprint Genetic polymorphisms in the human growth hormone-1 gene (GH1) and the risk of breast carcinoma
    Zefang Ren
    Department of Medicine, Vanderbilt University, Nashville, Tennessee 37232, USA
    Cancer 101:251-7. 2004
    ..The authors investigated the association of breast carcinoma with genetic polymorphisms in the GH1 gene in the Shanghai Breast Cancer Study...
  65. pmc Animal origin foods and colorectal cancer risk: a report from the Shanghai Women's Health Study
    Sang Ah Lee
    Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, 2525 West End Avenue, Nashville, TN 37203 1738, USA
    Nutr Cancer 61:194-205. 2009
    ..The latter was positively associated with colon cancer (RR = 1.4 for ever vs. never, 95% CI = 1.1-1.9). A possible role of cholesterol and environmental pollution in the etiology of CRC was suggested...
  66. ncbi request reprint Synergistic effects of STK15 gene polymorphisms and endogenous estrogen exposure in the risk of breast cancer
    Qi Dai
    Vanderbilt Center for Health Services Research, 1215 21st Avenue South, Medical Center East, Suite 6000, Nashville, TN 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 13:2065-70. 2004
    ....
  67. ncbi request reprint Soy food consumption is associated with lower risk of coronary heart disease in Chinese women
    Xianglan Zhang
    Department of Medicine, Center for Health Services Research, Vanderbilt University, Nashville, TN 37232, USA
    J Nutr 133:2874-8. 2003
    ..14; 95% CI, 0.04-0.48 for the highest vs. the lowest quartile of intake; P for trend = 0.001). This study provides, for the first time, direct evidence that soy food consumption may reduce the risk of CHD in women...
  68. ncbi request reprint Genetic variation in IGF1, IGF-1R, IGFALS, and IGFBP3 in breast cancer survival among Chinese women: a report from the Shanghai Breast Cancer Study
    Sandra L Deming
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Breast Cancer Res Treat 104:309-19. 2007
    ..9) for the N/A-A/A genotypes (rs6413441). Taken together, these data suggest that polymorphisms in the IGF-1R and IGFBP3 genes may be associated with altered survival among subgroups of breast cancer patients defined by menopausal status...
  69. ncbi request reprint Expression patterns of insulin-like growth factor 1 (IGF-I) and its receptor in mammary tissues and their associations with breast cancer survival
    Aesun Shin
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University, S1121 Medical Center North, 1161 21st Avenue S, Nashville, TN, 37232 2587, USA
    Breast Cancer Res Treat 105:55-61. 2007
    ..Our findings suggest that the expression of IGF-I and IGFIR genes may undergo substantial change over the course of breast tumorigenesis, and the pattern of changes may be associated with breast cancer prognosis...
  70. ncbi request reprint Parental medication use and risk of childhood acute lymphoblastic leukemia
    Wanqing Wen
    Department of Medicine, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA
    Cancer 95:1786-94. 2002
    ..As part of a large case-control study conducted by the Children's Cancer Group, we evaluated the association between maternal and paternal medication use and the risk of ALL in offspring...
  71. ncbi request reprint Birthweight, childhood growth and hypertension in adulthood
    Mingfang Zhao
    Center for Health Services Research, Vanderbilt University, Nashville, TN 37232 8300, USA
    Int J Epidemiol 31:1043-51. 2002
    ..Low birthweight (BW) and childhood growth have been hypothesized to be associated with an increased risk of hypertension in later life...
  72. doi request reprint The use of complementary and alternative medicine among Chinese women with breast cancer
    Zhi Chen
    Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt School of Medicine and Vanderbilt Ingram Cancer Center, Nashville, TN, USA
    J Altern Complement Med 14:1049-55. 2008
    ....
  73. pmc E-cadherin polymorphisms and breast cancer susceptibility: a report from the Shanghai Breast Cancer Study
    Alicia Beeghly-Fadiel
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Institute of Medicine and Public Health, Vanderbilt University Medical Center, Vanderbilt University School of Medicine, 2525 West End Avenue, 8th Floor, Nashville, TN 37203 1738, USA
    Breast Cancer Res Treat 121:445-52. 2010
    ....
  74. ncbi request reprint Correlation of blood sex steroid hormones with body size, body fat distribution, and other known risk factors for breast cancer in post-menopausal Chinese women
    Sonia M Boyapati
    Division of General Internal Medicine, Department of Medicine, Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN 37232 8300, USA
    Cancer Causes Control 15:305-11. 2004
    ..The objective of this analysis is to evaluate the association between measures of body size, dietary macronutrient intake, and reproductive factors with levels of endogenous sex hormones among women living in Shanghai, China...
  75. ncbi request reprint Cytochrome P450 1B1 and catechol-O-methyltransferase genetic polymorphisms and endometrial cancer risk in Chinese women
    Meng Hua Tao
    Vanderbilt Epidemiology Center, Vanderbilt University, 6009 Medical Center East, 1215 21st Avenue South, Nashville, TN 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 15:2570-3. 2006
  76. ncbi request reprint Impact of season of food frequency questionnaire administration on dietary reporting
    Jay H Fowke
    Vanderbilt University Medical Center, Nashville, TN 37232 8300, USA
    Ann Epidemiol 14:778-85. 2004
    ..This study investigates the effect of season of FFQ administration, a proxy for the recent diet, on FFQ responses...
  77. pmc A prospective study of dietary polyunsaturated fatty acids and colorectal cancer risk in Chinese women
    Harvey J Murff
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
    Cancer Epidemiol Biomarkers Prev 18:2283-91. 2009
    ..03). These results suggest that dietary PUFA and the ratio of n-6 to n-3 PUFA intake may be positively associated with colorectal cancer risk, and this association may be mediated in part through PGE(2) production...
  78. ncbi request reprint Population-based case-control study of CYP11A gene polymorphism and breast cancer risk
    Wei Zheng
    Drpartment of Medicine and Vanderbilt Ingram Cancer Centr, Vanderbilt University, Nashville, TN, USA
    Cancer Epidemiol Biomarkers Prev 13:709-14. 2004
    ..The results from this study indicate that the TAAAA repeat polymorphism near the promoter region of the CYP11A gene may be an important susceptibility factor for breast cancer risk...
  79. pmc Pregnancy, childrearing, and risk of stroke in Chinese women
    Xianglan Zhang
    Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt University Medical Center, Sixth Floor, Suite 600, 2525 West End Avenue, Nashville, TN 37203 1738, USA
    Stroke 40:2680-4. 2009
    ..Although it has been suggested that high gravidity and parity increase the risk for coronary heart disease, their associations with stroke are unclear...
  80. ncbi request reprint Physical activity, body size, and estrogen metabolism in women
    Charles E Matthews
    Vanderbilt Ingram Cancer Center, Center for Health Services Research, Vanderbilt University Medical Center, Medical Center East, Suite 6100, Nashville, TN 37232 8300, USA
    Cancer Causes Control 15:473-81. 2004
    ..We examined these relationships in cross-sectional analyses of 157 North American and Chinese women...
  81. pmc General and abdominal adiposity and risk of stroke in Chinese women
    Xianglan Zhang
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tenn 37203 1738, USA
    Stroke 40:1098-104. 2009
    ..Although both general and abdominal adiposity are well-established risk factors for coronary heart disease, their associations with stroke are less well characterized, particularly in generally lean Asian populations...
  82. ncbi request reprint Oral contraceptive use and breast cancer risk: modification by NAD(P)H:quinone oxoreductase (NQO1) genetic polymorphisms
    Jay H Fowke
    Center for Health Services Research, Vanderbilt University Medical Center, 6110 Medical Center East, Nashville, TN 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 13:1308-15. 2004
    ..43-6.25; C/T or T/T OR 0.49, 95% CI 0.29-0.81; P for interaction < 0.01). Our results require confirmation but suggest that the OC and breast cancer association depends on the ability to invoke protection from catechol estrogens...
  83. ncbi request reprint Insulin-like growth factor-I gene polymorphism and breast cancer risk in Chinese women
    Wanqing Wen
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA
    Int J Cancer 113:307-11. 2005
    ..22, 95% CI: 1.06-1.41, p for heterogeneity test = 0.524). The findings of this study support the hypothesis that IGF-I gene polymorphisms may be a significant genetic factor for breast cancer susceptibility...
  84. pmc Oxidative stress, obesity, and breast cancer risk: results from the Shanghai Women's Health Study
    Qi Dai
    Department of Medicine and Pharmacology, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Nashville, TN 37203 1738, USA
    J Clin Oncol 27:2482-8. 2009
    ..No prospective study has investigated whether levels of 15-F(2t)-isoprostane (15-F(2t)-IsoP) and its metabolite 2,3-dinor-5,6-dihydro-15-F(2t)-IsoP (15-F(2t)-IsoPM) are related to breast cancer risk...
  85. pmc Genetic polymorphism in the manganese superoxide dismutase gene, antioxidant intake, and breast cancer risk: results from the Shanghai Breast Cancer Study
    Qiuyin Cai
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA
    Breast Cancer Res 6:R647-55. 2004
    ....
  86. pmc Dietary calcium and magnesium intakes and the risk of type 2 diabetes: the Shanghai Women's Health Study
    Raquel Villegas
    Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN 37203 1738, USA
    Am J Clin Nutr 89:1059-67. 2009
    ..Diet plays a key role in the development of type 2 diabetes (T2D), but little is known about the contributions of specific nutrients in populations in which dietary patterns differ from Western populations...
  87. pmc Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1
    Wei Zheng
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Nat Genet 41:324-8. 2009
    ..01). These results strongly implicate 6q25.1 as a susceptibility locus for breast cancer...
  88. pmc Is green tea drinking associated with a later onset of breast cancer?
    Qi Dai
    Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, TN 37203 1738, USA
    Ann Epidemiol 20:74-81. 2010
    ..Because of the substantial difference in levels of estrogens between premenopausal and postmenopausal women, the relationship between tea consumption and breast cancer risk may depend on menopausal status...
  89. pmc Isothiocyanate exposure, glutathione S-transferase polymorphisms, and colorectal cancer risk
    Gong Yang
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
    Am J Clin Nutr 91:704-11. 2010
    ..Glutathione S-transferases (GSTs) are involved in the metabolism and elimination of isothiocyanates; thus, genetic variations in these enzymes may affect in vivo bioavailability and the activity of isothiocyanates...
  90. ncbi request reprint Urinary isothiocyanate levels, brassica, and human breast cancer
    Jay H Fowke
    Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232 8300, USA
    Cancer Res 63:3980-6. 2003
    ..In conclusion, greater Brassica vegetable consumption, as measured by the urinary ITC biomarker, was associated with significantly reduced breast cancer risk among Chinese women...
  91. ncbi request reprint Genetic polymorphisms in the estrogen receptor alpha gene and risk of breast cancer: results from the Shanghai Breast Cancer Study
    Qiuyin Cai
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37232, USA
    Cancer Epidemiol Biomarkers Prev 12:853-9. 2003
    ..No apparent synergetic effect of these two polymorphisms was identified. Results of this study indicate that genetic polymorphisms in the ER-alpha gene may play a role in the etiology of breast cancer...
  92. ncbi request reprint Association of breast cancer risk with a GT dinucleotide repeat polymorphism upstream of the estrogen receptor-alpha gene
    Qiuyin Cai
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37232, USA
    Cancer Res 63:5727-30. 2003
    ..Results of this study indicate that the GT dinucleotide repeat polymorphism in ER-alpha gene promoter region may be a new biomarker for genetic susceptibility to breast cancer...
  93. ncbi request reprint Reproducibility and validity of the Shanghai Women's Health Study physical activity questionnaire
    Charles E Matthews
    Department of Medicine, Vanderbilt Ingram Cancer Center, Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN 37232 8300, USA
    Am J Epidemiol 158:1114-22. 2003
    ..88). These data indicate that the SWHS PAQ is a reproducible and valid measure of exercise behaviors and that it demonstrates utility in stratifying women by levels of important lifestyle activities (e.g., housework, walking, cycling)...
  94. pmc Evaluation of breast cancer susceptibility loci in Chinese women
    Jirong Long
    Division of Epidemiology, Department ofMedicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Nashville, TN 37203 1738, USA
    Cancer Epidemiol Biomarkers Prev 19:2357-65. 2010
    ..Recent genome-wide association studies (GWAS), mostly conducted among women of European ancestry, have identified 16 single-nucleotide polymorphisms (SNP) associated with breast cancer...
  95. pmc Fruit and vegetable consumption and risk of distal gastric cancer in the Shanghai Women's and Men's Health studies
    Meira Epplein
    Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, 2525 West End Avenue, Sixth Floor, Nashville, TN 37203, USA
    Am J Epidemiol 172:397-406. 2010
    ..67). No associations between dietary intakes of select antioxidant micronutrients were seen for men or women. Fruit intake is inversely associated with distal gastric cancer risk among men in Shanghai, China...
  96. ncbi request reprint A population-based case-control study of the Arg399Gln polymorphism in DNA repair gene XRCC1 and risk of breast cancer
    Xiao Ou Shu
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37232 8300, USA
    Cancer Epidemiol Biomarkers Prev 12:1462-7. 2003
    ..60; 95% CI, 0.18-1.97). The overall results of the study suggest that Arg399Gln polymorphism of the XRCC1 gene alone may not play a substantial role in the risk of breast cancer among Chinese women...
  97. pmc Circulating 25-hydroxyvitamin D and risk of epithelial ovarian cancer: Cohort Consortium Vitamin D Pooling Project of Rarer Cancers
    Wei Zheng
    Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA
    Am J Epidemiol 172:70-80. 2010
    ..01). In conclusion, this large pooled analysis did not support an overall association between circulating 25(OH)D and ovarian cancer risk, except possibly among overweight women...
  98. pmc Genetic and clinical predictors for breast cancer risk assessment and stratification among Chinese women
    Wei Zheng
    Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, 2525 West End Avenue, Nashville, TN 37203 1738, USA
    J Natl Cancer Inst 102:972-81. 2010
    ..No risk assessment model that incorporates both genetic and clinical predictors is currently available to predict breast cancer risk in this population...
  99. ncbi request reprint Diagnostic X-rays and ultrasound exposure and risk of childhood acute lymphoblastic leukemia by immunophenotype
    Xiao Ou Shu
    University of Minnesota, Minneapolis, Minnesota, USA
    Cancer Epidemiol Biomarkers Prev 11:177-85. 2002
    ....
  100. ncbi request reprint Genetic polymorphisms in GSTM1, GSTP1, and GSTT1 and the risk for breast cancer: results from the Shanghai Breast Cancer Study and meta-analysis
    Kathleen M Egan
    Department of Medicine and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 27232 8300, USA
    Cancer Epidemiol Biomarkers Prev 13:197-204. 2004
    ....
  101. pmc Prevalence and determinants of hyperuricemia in middle-aged, urban Chinese men
    Raquel Villegas
    Vanderbilt Epidemiology Center, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37203 1738, USA
    Metab Syndr Relat Disord 8:263-70. 2010
    ..Hyperuricemia is associated with metabolic syndrome and has emerged as a marker for both type 2 diabetes and cardiovascular disease. We estimated the prevalence and lifestyle risk factors of hyperuricemia in middle-aged, urban Chinese men...

Research Grants28

  1. Soy Food and Coronary Heart Disease in Women
    Xiao Ou Shu; Fiscal Year: 2007
    ....
  2. Cohort Study of Cancer-Inhibitory Dietary Factors in Men
    Xiao Ou Shu; Fiscal Year: 2007
    ..The results from this study may guide new strategies in the primary prevention of common cancers in both Western and Asian men. ..
  3. Vanderbilt-Shanghai Chronic Disease Research Training Program
    Xiao Ou Shu; Fiscal Year: 2009
    ..This program will have significant impact on chronic disease research and prevention in China, and possibly extend to other developing countries. ..
  4. Cohort Study of Cancer-Inhibitory Dietary Factors in Men
    Xiao Ou Shu; Fiscal Year: 2010
    ..The results from this study may guide new strategies in the primary prevention of common cancers in both Western and Asian men. ..
  5. Breast Cancer Survival: Lifestyle and Genetic Determinants
    Xiao Ou Shu; Fiscal Year: 2010
    ..The proposed study, built on successfully implemented cohort studies, will be extremely timely and cost-efficient. ..
  6. Soyfood, gene polymorphisms and endometrial cancer risk
    Xiao Ou Shu; Fiscal Year: 2010
    ..abstract_text> ..
  7. Cohort Study of Cancer inhibitory Factors in Men
    Xiao Ou Shu; Fiscal Year: 2006
    ....
  8. MALIGNANT GERM CELL TUMORS IN CHILDREN
    Xiao Shu; Fiscal Year: 2001
    ..The relatively large sample size will provide sufficient statistical power to address the hypotheses being investigated. ..
  9. Soyfood, gene polymorphisms and endometrial cancer risk
    Xiao Ou Shu; Fiscal Year: 2005
    ..Consumption level of soyfood is high and hysterectomy rates are extremely low among Chinese women, providing a unique opportunity to test the hypotheses posed in the application that are difficult to be evaluated in the U.S. population. ..
  10. Breast Cancer Survival: Lifestyle and Genetic Determinants
    Xiao Ou Shu; Fiscal Year: 2009
    ..The proposed study, built on successfully implemented cohort studies, will be extremely timely and cost-efficient. ..