Satish R Raj

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. ncbi request reprint Acetylcholinesterase inhibition improves tachycardia in postural tachycardia syndrome
    Satish R Raj
    Autonomic Dysfunction Center, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University, 1161 21st Ave South, Nashville, TN 37232 2195, USA
    Circulation 111:2734-40. 2005
  2. ncbi request reprint Case report: Marathon runner with severe autonomic failure
    Emily M Garland
    Autonomic Dysfunction Center, Vanderbilt University, Nashville, TN 37232, USA
    Lancet 366:S13. 2005
  3. ncbi request reprint Techniques used for the determination of blood volume
    Andrew C Ertl
    Autonomic Dysfunction Center, Departments of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 2195, USA
    Am J Med Sci 334:32-6. 2007
  4. pmc Comparative efficacy of yohimbine against pyridostigmine for the treatment of orthostatic hypotension in autonomic failure
    Cyndya Shibao
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tenn, USA
    Hypertension 56:847-51. 2010
  5. pmc Long-term treatment with rituximab of autoimmune autonomic ganglionopathy in a patient with lymphoma
    Ryan Hollenbeck
    MsCI, Autonomic Dysfunction Center, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University School of Medicine, AA3228 Medical Center North, 1161 21st Ave S, Nashville, TN 37232 2195, USA
    Arch Neurol 68:372-5. 2011
  6. pmc Medical therapy and physical maneuvers in the treatment of the vasovagal syncope and orthostatic hypotension
    Satish R Raj
    Autonomic Dysfunction Center, Vanderbilt University School of Medicine, Nashville, TN 37232 2195, USA
    Prog Cardiovasc Dis 55:425-33. 2013
  7. pmc Rationale for the prevention of syncope trial IV: assessment of midodrine
    Satish R Raj
    Division of Clinical Pharmacology, Departments of Medicine and Pharmacology, Vanderbilt University, Nashville, TN 37232 2195, USA
    Clin Auton Res 22:275-80. 2012
  8. ncbi request reprint Sodium paradoxically reduces the gastropressor response in patients with orthostatic hypotension
    Satish R Raj
    Autonomic Dysfunction Center, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University, Nashville, TN, USA
    Hypertension 48:329-34. 2006
  9. ncbi request reprint Blood volume perturbations in the postural tachycardia syndrome
    Satish R Raj
    Autonomic Dysfunction Center, Division of Clinical Pharmacology, Departments of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 2195, USA
    Am J Med Sci 334:57-60. 2007
  10. ncbi request reprint Renin-aldosterone paradox and perturbed blood volume regulation underlying postural tachycardia syndrome
    Satish R Raj
    Division of Clinical Pharmacology, Vanderbilt University, Nashville, Tenn 37232 2195, USA
    Circulation 111:1574-82. 2005

Collaborators

Detail Information

Publications61

  1. ncbi request reprint Acetylcholinesterase inhibition improves tachycardia in postural tachycardia syndrome
    Satish R Raj
    Autonomic Dysfunction Center, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University, 1161 21st Ave South, Nashville, TN 37232 2195, USA
    Circulation 111:2734-40. 2005
    ..The objective of this study was to test the hypothesis that acetylcholinesterase inhibitors will attenuate the tachycardia and improve symptom burden in patients with POTS...
  2. ncbi request reprint Case report: Marathon runner with severe autonomic failure
    Emily M Garland
    Autonomic Dysfunction Center, Vanderbilt University, Nashville, TN 37232, USA
    Lancet 366:S13. 2005
  3. ncbi request reprint Techniques used for the determination of blood volume
    Andrew C Ertl
    Autonomic Dysfunction Center, Departments of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 2195, USA
    Am J Med Sci 334:32-6. 2007
  4. pmc Comparative efficacy of yohimbine against pyridostigmine for the treatment of orthostatic hypotension in autonomic failure
    Cyndya Shibao
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tenn, USA
    Hypertension 56:847-51. 2010
    ..Engaging residual sympathetic tone with yohimbine is a more effective approach to improve orthostatic hypotension as compared with pyridostigmine in patients with severe orthostatic hypotension...
  5. pmc Long-term treatment with rituximab of autoimmune autonomic ganglionopathy in a patient with lymphoma
    Ryan Hollenbeck
    MsCI, Autonomic Dysfunction Center, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University School of Medicine, AA3228 Medical Center North, 1161 21st Ave S, Nashville, TN 37232 2195, USA
    Arch Neurol 68:372-5. 2011
    ..To report on the response to therapy in a patient with autoimmune autonomic ganglionopathy with a high titer of an autoantibody directed against the α-3 subunit of the nicotinic acetylcholine receptor (nAChR) of the autonomic ganglia...
  6. pmc Medical therapy and physical maneuvers in the treatment of the vasovagal syncope and orthostatic hypotension
    Satish R Raj
    Autonomic Dysfunction Center, Vanderbilt University School of Medicine, Nashville, TN 37232 2195, USA
    Prog Cardiovasc Dis 55:425-33. 2013
    ..We aim to review the literature on these different therapy choices and to give recommendations on tailored approaches to the treatment of these conditions...
  7. pmc Rationale for the prevention of syncope trial IV: assessment of midodrine
    Satish R Raj
    Division of Clinical Pharmacology, Departments of Medicine and Pharmacology, Vanderbilt University, Nashville, TN 37232 2195, USA
    Clin Auton Res 22:275-80. 2012
    ..A few studies have suggested that it may be beneficial in syncope, but all have had significant methodological limitations. A placebo-controlled clinical trial of midodrine for the prevention of vasovagal syncope is needed...
  8. ncbi request reprint Sodium paradoxically reduces the gastropressor response in patients with orthostatic hypotension
    Satish R Raj
    Autonomic Dysfunction Center, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University, Nashville, TN, USA
    Hypertension 48:329-34. 2006
    ..These data suggest a potentially important role for gastrointestinal osmolality in the activation of the sympathetic nervous system leading to cardiovascular reflexes responsible for the gastropressor response...
  9. ncbi request reprint Blood volume perturbations in the postural tachycardia syndrome
    Satish R Raj
    Autonomic Dysfunction Center, Division of Clinical Pharmacology, Departments of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 2195, USA
    Am J Med Sci 334:57-60. 2007
    ..The blood volume has been found to be low in many patients with POTS. This article will review some of the data regarding blood volume perturbations in POTS, blood volume regulation in POTS, and potential treatment approaches...
  10. ncbi request reprint Renin-aldosterone paradox and perturbed blood volume regulation underlying postural tachycardia syndrome
    Satish R Raj
    Division of Clinical Pharmacology, Vanderbilt University, Nashville, Tenn 37232 2195, USA
    Circulation 111:1574-82. 2005
    ..We prospectively tested the hypothesis that patients with POTS are hypovolemic compared with healthy controls and explored the role of plasma renin activity and aldosterone in the regulation of plasma volume...
  11. pmc Propranolol decreases tachycardia and improves symptoms in the postural tachycardia syndrome: less is more
    Satish R Raj
    Departments of Medicine, Division of Clinical Pharmacology, Autonomic Dysfunction Center, Vanderbilt University, Nashville, Tenn 37232 2195, USA
    Circulation 120:725-34. 2009
    ..We tested the hypothesis that propranolol will attenuate the tachycardia and improve symptom burden in patients with POTS. In protocol 1, a low dose (20 mg) was compared with placebo, and the dose response was assessed in protocol 2...
  12. pmc Nitric oxide and regulation of heart rate in patients with postural tachycardia syndrome and healthy subjects
    Alfredo Gamboa
    Division of Clinical Pharmacology, Vanderbilt University, Nashville, TN, USA
    Hypertension 61:376-81. 2013
    ..We found no evidence of a primary alteration in NO function in POTS. If NO dysfunction plays a role in POTS, it is through its interaction with the autonomic nervous system...
  13. ncbi request reprint Norepinephrine transporter blockade with atomoxetine induces hypertension in patients with impaired autonomic function
    Cyndya Shibao
    Department of Medicine, Division of Clinical Pharmacology, and the Autonomic Dysfunction Center, Vanderbilt University School of Medicine, Nashville, TN 37212, USA
    Hypertension 50:47-53. 2007
    ..Caution should be exercised when this medication is used in patients with milder form of autonomic impairment...
  14. pmc Renal impairment of pure autonomic failure
    Emily M Garland
    Autonomic Dysfunction Center, Vanderbilt University, Nashville, TN 37232 2195, USA
    Hypertension 54:1057-61. 2009
    ..73 m2; P=0.022) compared with patients who did not have supine hypertension. These findings may indicate that renal function is diminished in PAF in association with supine hypertension...
  15. pmc Diurnal variability in orthostatic tachycardia: implications for the postural tachycardia syndrome
    Jordan A Brewster
    Division of Clinical Pharmacology, Vanderbilt University School of Medicine, AA3228 Medical Center North, 1161 21st Avenue South, Nashville, TN 37232 2195, USA
    Clin Sci (Lond) 122:25-31. 2012
    ..Given the importance of orthostatic tachycardia in diagnosing POTS, this diurnal variability should be considered in the clinic as it may affect the diagnosis of POTS...
  16. pmc Angiotensin II, independent of plasma renin activity, contributes to the hypertension of autonomic failure
    Amy C Arnold
    Division of Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232 6602, USA
    Hypertension 61:701-6. 2013
    ..Furthermore, these studies suggest that elevations in Ang II contribute to the hypertension of autonomic failure, and provide rationale for the use of AT(1) receptor blockers for treatment of these patients...
  17. pmc Synergistic effect of norepinephrine transporter blockade and α-2 antagonism on blood pressure in autonomic failure
    Luis E Okamoto
    Vanderbilt Autonomic Dysfunction Center, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
    Hypertension 59:650-6. 2012
    ..Safety studies are required to address the clinical usefulness of this pharmacological approach...
  18. pmc Excessive nitric oxide function and blood pressure regulation in patients with autonomic failure
    Alfredo Gamboa
    Department of Medicine, Vanderbilt University, Nashville, Tenn 37212, USA
    Hypertension 51:1531-6. 2008
    ..Potentiation of NO could be used in the treatment of supine hypertension, and its inhibition offers a novel approach to improve orthostatic hypotension...
  19. pmc Nocturnal blood pressure dipping in the hypertension of autonomic failure
    Luis E Okamoto
    Division of Clinical Pharmacology and Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
    Hypertension 53:363-9. 2009
    ..Dipping was not associated with increased nocturnal urinary sodium or volume excretion or less severe autonomic failure. Thus, mechanisms independent of autonomic pathways contribute to BP dipping in these patients...
  20. pmc Neurohumoral and haemodynamic profile in postural tachycardia and chronic fatigue syndromes
    Luis E Okamoto
    Vanderbilt Autonomic Dysfunction Center, Vanderbilt University School of Medicine, Nashville, TN, U S A
    Clin Sci (Lond) 122:183-92. 2012
    ..CFS-POTS patients have higher markers of sympathetic activation, but are part of the spectrum of POTS. Targeting this sympathetic activation should be considered in the treatment of these patients...
  21. pmc Desmopressin acutely decreases tachycardia and improves symptoms in the postural tachycardia syndrome
    Samuel T Coffin
    Autonomic Dysfunction Center, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA
    Heart Rhythm 9:1484-90. 2012
    ..Increasing blood volume is a promising approach to this problem...
  22. pmc Effects of norepinephrine reuptake inhibition on postural tachycardia syndrome
    Elizabeth A Green
    Autonomic Dysfunction Center, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University, Nashville, TN
    J Am Heart Assoc 2:e000395. 2013
    ..We sought to determine whether NRI with atomoxetine increases standing tachycardia or worsens the symptom burden in POTS patients...
  23. pmc Understanding the placebo effect in clinical trials for postural tachycardia syndrome
    Victor C Nwazue
    Autonomic Dysfunction Center, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University, Nashville, TN, USA
    Clin Exp Pharmacol Physiol 41:325-30. 2014
    ..These data highlight the need for a placebo arm in haemodynamic clinical trials in POTS and may have important implications for the diagnosis of these patients...
  24. pmc Altered systemic hemodynamic and baroreflex response to angiotensin II in postural tachycardia syndrome
    Hossam I Mustafa
    Division of Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232 2195, USA
    Circ Arrhythm Electrophysiol 5:173-80. 2012
    ..In this study, we assess systemic and renal hemodynamic and functional responses to Ang II infusion in patients with POTS compared with healthy controls...
  25. ncbi request reprint Endogenous substance P modulates human cardiovascular regulation at rest and during orthostatic load
    Matthew V Dzurik
    Department of Pediatrics, Autonomic Dysfunction Center, AA 3228 Medical Center North, Vanderbilt University School of Medicine, 1161 21st Ave South, Nashville, TN 37232 2195, USA
    J Appl Physiol 102:2092-7. 2007
    ..This study is consistent with a role for SP afferents in supporting peripheral vascular resistance...
  26. pmc Melatonin reduces tachycardia in postural tachycardia syndrome: a randomized, crossover trial
    Elizabeth A Green
    Division of Clinical Pharmacology, Department of Medicine, Autonomic Dysfunction Center, Vanderbilt University, Nashville, TN, USA
    Cardiovasc Ther 32:105-12. 2014
    ..Medications that restrain HR are a promising approach to this problem...
  27. pmc Low-dose propranolol and exercise capacity in postural tachycardia syndrome: a randomized study
    Amy C Arnold
    Department of Medicine, Division of Clinical Pharmacology, Vanderbilt University, Nashville, TN, USA
    Neurology 80:1927-33. 2013
    ..To determine the effect of low-dose propranolol on maximal exercise capacity in patients with postural tachycardia syndrome (POTS)...
  28. pmc Diagnosing postural tachycardia syndrome: comparison of tilt testing compared with standing haemodynamics
    Walker B Plash
    Autonomic Dysfunction Center, Vanderbilt University School of Medicine, Nashville, TN 37232 2195, USA
    Clin Sci (Lond) 124:109-14. 2013
    ..The 30 bpm ΔHR criterion is not suitable for 30 min tilt. Diagnosis of POTS should consider orthostatic intolerance criteria and not be based solely on orthostatic tachycardia regardless of test used...
  29. pmc Portal osmopressor mechanism linked to transient receptor potential vanilloid 4 and blood pressure control
    Julia McHugh
    Autonomic Dysfunction Center, Departments of Medicine, Vanderbilt University, Nashville, TN 37232 2195, USA
    Hypertension 55:1438-43. 2010
    ..The same volume of physiological saline does not elicit an increase in BP, suggesting osmolality as the stimulus. The osmopressor response to water, and Trpv4 thus represent new factors now implicated in the physiology of BP regulation...
  30. pmc Estimation of sleep disturbances using wrist actigraphy in patients with postural tachycardia syndrome
    Kanika Bagai
    Autonomic Dysfunction Center, Vanderbilt University School of Medicine, Nashville, TN, USA Department of Neurology, Vanderbilt University School of Medicine, Nashville, TN, USA
    Auton Neurosci 177:260-5. 2013
    ..Patients with postural tachycardia syndrome (POTS) commonly complain of fatigue, unrefreshing sleep, daytime sleepiness and diminished quality of life. The study objective was to assess sleep quality in POTS patients using wrist actigraphy...
  31. ncbi request reprint Postural tachycardia syndrome and inappropriate sinus tachycardia: role of autonomic modulation and sinus node automaticity
    Victor C Nwazue
    Autonomic Dysfunction Center, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University, Nashville, TN
    J Am Heart Assoc 3:e000700. 2014
    ..We hypothesized that intrinsic heart rate (IHR) after autonomic blockade would be increased in patients with IST but not POTS...
  32. pmc Acute hemodynamic effects of a selective serotonin reuptake inhibitor in postural tachycardia syndrome: a randomized, crossover trial
    Philip L Mar
    1Autonomic Dysfunction Center, Department of Medicine, Vanderbilt University, Nashville, USA
    J Psychopharmacol 28:155-61. 2014
    ..We hypothesized that they act to increase blood pressure and attenuate reflex tachycardia, thereby improving symptoms. Acute hemodynamic profiles after SSRI administration in POTS patients have not previously been reported...
  33. pmc Distal sudomotor findings in postural tachycardia syndrome
    Amanda Catherine Peltier
    Autonomic Dysfunction Center, Vanderbilt University School of Medicine, Nashville, USA
    Clin Auton Res 20:93-9. 2010
    ..Norepinephrine levels above 600 pg/ml have also been used to delineate patients with a hyperadrenergic state. This study aims to determine the relationship of sudomotor abnormalities to other aspects of dysautonomia in POTS...
  34. pmc Coexistent autoimmune autonomic ganglionopathy and myasthenia gravis associated with non-small-cell lung cancer
    Amanda C Peltier
    Department of Neurology, Vanderbilt University School of Medicine, A 0118 Medical Center North, Nashville, Tennessee 37232, USA
    Muscle Nerve 41:416-9. 2010
    ....
  35. pmc Gynecological and menstrual disorders in women with vasovagal syncope
    Prasuna Muppa
    Division of Clinical Pharmacology, Department of Medicine, Autonomic Dysfunction Center, Vanderbilt University School of Medicine, AA3228 Medical Center North, 1161 21st Avenue South, Nashville, TN 37232 2195, USA
    Clin Auton Res 23:117-22. 2013
    ..This case-control study assessed the effects of the menstrual cycle on lightheadedness episodes and compared the gynecological and pregnancy history of VVS patients to healthy subjects...
  36. pmc Dysautonomia: perioperative implications
    Hossam I Mustafa
    Autonomic Dysfunction Center, Division of Clinical Pharmacology, Department of Medicine, Autonomic Rare Disease Clinical Research Consortium, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2195, USA
    Anesthesiology 116:205-15. 2012
    ....
  37. ncbi request reprint Clonidine for the treatment of supine hypertension and pressure natriuresis in autonomic failure
    Cyndya Shibao
    Division of Clinical Pharmacology, Department of Medicine and Pharmacology, The Autonomic Dysfunction Center, Vanderbilt University School of Medicine, Nashville, TN, USA
    Hypertension 47:522-6. 2006
    ..66; P=0.043). These results are consistent with residual sympathetic tone contributing to supine hypertension in autonomic failure, which can be targeted with clonidine to decrease BP and nocturnal natriuresis...
  38. pmc Abnormalities of angiotensin regulation in postural tachycardia syndrome
    Hossam I Mustafa
    Division of Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 2195, USA
    Heart Rhythm 8:422-8. 2011
    ..In this study, we sought to more fully characterize the renin-angiotensin-aldosterone system (RAAS) to gain a better understanding of the pathophysiology of POTS...
  39. pmc Sleep disturbances and diminished quality of life in postural tachycardia syndrome
    Kanika Bagai
    Paden Dysautonomia Center and Department of Neurology, Vanderbilt University, Nashville, TN, USA
    J Clin Sleep Med 7:204-10. 2011
    ..This study's objective was to assess the sleep quality and health-related quality of life in patients with POTS as compared with healthy control subjects...
  40. pmc SHC2 gene copy number in multiple system atrophy (MSA)
    Marcus C Ferguson
    Autonomic Dysfunction Center, Department of Medicine, Vanderbilt University, AA3228 Medical Center North, Nashville, TN, 37232 2195, USA
    Clin Auton Res 24:25-30. 2014
    ..Our cohort included 105 carefully phenotyped individuals with MSA...
  41. ncbi request reprint Orthostatic hypotension-related hospitalizations in the United States
    Cyndya Shibao
    Department of Medicine, Division of Clinical Pharmacology, Vanderbilt University, Nashville, Tenn 37212, USA
    Am J Med 120:975-80. 2007
    ..Nevertheless, the precise burden of this condition in the US is currently unknown...
  42. doi request reprint Arrhythmogenic Munchausen syndrome culminating in caffeine-induced ventricular tachycardia
    Joseph C Vaglio
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
    J Electrocardiol 44:229-31. 2011
    ..Our patient both simulated and stimulated her arrhythmias with an ECG rhythm generator and intentional caffeine intoxication. To our knowledge, this is the first report of caffeine overdose for arrhythmogenesis...
  43. pmc Confounders of vasovagal syncope: orthostatic hypotension
    Victor C Nwazue
    Division of Clinical Pharmacology, Department of Medicine, Autonomic Dysfunction Center, Vanderbilt University School of Medicine, AA3228 Medical Center North, 1161 21st Avenue South, Nashville, TN 37232 2195, USA
    Cardiol Clin 31:89-100. 2013
    ..This article reviews the presentation of the vasovagal syncope confounder and the putative pathophysiology of orthostatic hypotension, and suggests options for nonpharmacologic and pharmacologic management...
  44. pmc Gynecologic disorders and menstrual cycle lightheadedness in postural tachycardia syndrome
    Kiffany J Peggs
    Paden Autonomic Dysfunction Service, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, USA
    Int J Gynaecol Obstet 118:242-6. 2012
    ..To assess differences in gynecologic history and lightheadedness during menstrual cycle phases among patients with POTS and healthy control women...
  45. ncbi request reprint The importance of recognizing postural pseudoanemia
    Fred Goldner
    Autonomic Dsyfunction Center, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 2195, USA
    Compr Ther 32:51-5. 2006
    ..In reality, these changes represent postural pseudoanemia, a normal physiological response to a change in position from standing to lying...
  46. pmc Confounders of vasovagal syncope: postural tachycardia syndrome
    Victor C Nwazue
    Division of Clinical Pharmacology, Department of Medicine, Autonomic Dysfunction Center, Vanderbilt University School of Medicine, AA3228 Medical Center North, 1161 21st Avenue South, Nashville, TN 37232 2195, USA
    Cardiol Clin 31:101-9. 2013
    ..This article reviews the presentation of postural tachycardia syndrome and its putative pathophysiology and presents an approach to nonpharmacologic and pharmacologic management...
  47. ncbi request reprint The Second Prevention of Syncope Trial (POST II)--a randomized clinical trial of fludrocortisone for the prevention of neurally mediated syncope: rationale and study design
    Satish R Raj
    Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University, Nashville, TN, USA
    Am Heart J 151:1186.e11-7. 2006
    ..05...
  48. ncbi request reprint Role of hypotension in heart rate turbulence physiology
    Satish R Raj
    Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Heart Rhythm 2:820-7. 2005
    ..Heart rate turbulence is a recently described cardiac prognostic marker that may be mediated by arterial baroreceptor sensitivity, suggesting it is induced by a brief initial hypotension...
  49. doi request reprint Stimulation of both type I and type II corticosteroid receptors blunts counterregulatory responses to subsequent hypoglycemia in healthy man
    Stephanie M Gustavson
    Department of Medicine, Div of Diabetes, Endocrinology, and Metabolism, Vanderbilt University Medical Center 7465 MRB IV, Nashville, TN 37232 0475, USA
    Am J Physiol Endocrinol Metab 294:E506-12. 2008
    ..Both type I and type II corticosteroid receptors may be involved in the multiple mechanisms controlling counterregulatory responses to hypoglycemia in healthy man...
  50. pmc Sleep syncope: treatment with a permanent pacemaker
    Jason A Rytlewski
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 2195, USA
    Pacing Clin Electrophysiol 35:e206-9. 2012
    ..Implantation of a dual chamber pacemaker (5-year follow-up) "cured" her of further syncope. This is a report of pacemaker use for this unusual form of reflex syncope...
  51. ncbi request reprint What is the optimal orthostatic stress to diagnose orthostatic hypotension?
    Satish R Raj
    Clin Auton Res 15:67-8. 2005
  52. ncbi request reprint Permanent cardiac pacing to prevent vasovagal syncope
    Satish R Raj
    Cardiovascular Research Group, University of Calgary, Calgary, Alberta, Canada
    Curr Opin Cardiol 17:90-5. 2002
    ..The second Vasovagal Pacemaker Study will quantify the true benefits of pacing for vasovagal syncope and assess the role of rate-drop response algorithms...
  53. ncbi request reprint Syncope: investigation and treatment
    Satish R Raj
    Faculty of Medicine, University of Calgary, Health Sciences Centre, 3330 Hospital Drive, NW, Calgary, Alberta, T2N 4N1, Canada
    Curr Cardiol Rep 4:363-70. 2002
    ....
  54. ncbi request reprint Paced QT dispersion and QT morphology after radiofrequency atrioventricular junction ablation: impact of left ventricular function
    Satish R Raj
    Division of Cardiology, Foothills Medical Center and the Cardiovascular Disease Research Group, University of Calgary, Calgary, Alberta, Canada
    Pacing Clin Electrophysiol 26:662-8. 2003
    ..02) function groups. Following AVJ ablation, QTdisp increased during a sudden rate drop in patients with reduced LV function, but not in patients with normal LV function...
  55. ncbi request reprint Activity-responsive pacing produces long-term heart rate variability
    Satish R Raj
    Cardiovascular Research Group, University of Calgary, Calgary, Alberta, Canada
    J Cardiovasc Electrophysiol 15:179-83. 2004
    ..We tested the hypothesis that long-term HRV arises from physical activity in a randomized cross-over study in patients with rate-responsive pacemakers...
  56. pmc The beat goes on--driven by a cardiac calcium clock?
    Satish R Raj
    Heart Rhythm 5:701-3. 2008
  57. ncbi request reprint Letter regarding article by Adamson et al, "Continuous autonomic assessment in patients with symptomatic heart failure: prognostic value of heart rate variability measured by an implanted cardiac resynchronization device"
    Satish R Raj
    Circulation 112:e37-8; author reply e37-8. 2005
  58. ncbi request reprint Postural pseudoanemia: posture-dependent change in hematocrit
    Giris Jacob
    Jacob Recanati Autonomic Dysfunction Center, Internal Medicine C, Rambam Medical Center, Haifa, Israel
    Mayo Clin Proc 80:611-4. 2005
    ..In reality, these changes represent postural pseudoanemia, a normal physiological response to a change in position from standing to lying (and vice versa)...
  59. ncbi request reprint Standard Deviation of Sequential Five-Minute R-R Interval Means (SDANN) is a prognostic marker, but not necessarily an autonomic marker
    Satish R Raj
    J Am Coll Cardiol 48:1285-6; author reply 1286. 2006
  60. ncbi request reprint Precordial QT dispersion does not predict inducibility of ventricular tachyarrhythmias at post-revascularization electrophysiologic study
    Satish R Raj
    Division of Cardiology, Foothills Medical Centre and the Cardiovascular Disease Research Group, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, Canada, T2N 4N1
    J Interv Card Electrophysiol 6:25-33. 2002
    ..We tested the hypothesis that revascularization would decrease QT interval dispersion and that QT interval dispersion would predict the outcome of the electrophysiologic study following revascularization...

Research Grants3

  1. The Role of Epinephrine in Neurally Mediated Syncope
    Satish Raj; Fiscal Year: 2007
    ..Using these Specific Aims, we will test the hypothesis that epinephrine or its receptors play an important role in the pathogenesis of neurally mediated syncope ..
  2. Aldosterone and Sodium Regulation in Postural Tachycardia Syndrome
    Satish R Raj; Fiscal Year: 2010
    ....