Brenda T Pun

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. doi request reprint Implementing the 2013 PAD guidelines: top ten points to consider
    Brenda T Pun
    Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA
    Semin Respir Crit Care Med 34:223-35. 2013
  2. doi request reprint Delirium monitoring in the ICU: strategies for initiating and sustaining screening efforts
    Brenda T Pun
    Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University, Nashville, Tennessee, USA
    Semin Respir Crit Care Med 34:179-88. 2013
  3. ncbi request reprint The importance of diagnosing and managing ICU delirium
    Brenda T Pun
    RN, MSN, Center for Health Services Research, Vanderbilt Medical Center, Nashville, TN 37232 8300, USA
    Chest 132:624-36. 2007
  4. doi request reprint Delirium in the intensive care unit: assessment and management
    Brenda T Pun
    Vanderbilt University School of Nursing, Department of Medicine, Division of Allergy Pulmonary Critical Care Medicine, and Center for Health Services Research, 1215 21st Ave S, Nashville, TN 37232, USA
    AACN Adv Crit Care 22:225-37. 2011
  5. ncbi request reprint The sedation of critically ill adults: Part 1: Assessment. The first in a two-part series focuses on assessing sedated patients in the ICU
    Brenda T Pun
    Vanderbilt University Medical Center, Nashville, TN, USA
    Am J Nurs 107:40-8; quiz 49. 2007
  6. ncbi request reprint The sedation of critically ill adults: part 2: management
    Brenda T Pun
    Vanderbilt University Medical Center in Nashville, TN, USA
    Am J Nurs 107:40-9; quiz 50. 2007
  7. pmc Long-term cognitive and psychological outcomes in the awakening and breathing controlled trial
    James C Jackson
    Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232 8300, USA
    Am J Respir Crit Care Med 182:183-91. 2010
  8. pmc Delirium as a predictor of long-term cognitive impairment in survivors of critical illness
    Timothy D Girard
    Division of Allergy, Pulmonary, and Critical Care Medicine, Center for Health Services Research, Department of Medicine, Vanderbilt University School of Medicine, and Department of Medicine, Saint Thomas Hospital, Nashville, TN, USA
    Crit Care Med 38:1513-20. 2010
  9. pmc Delirium and sedation recognition using validated instruments: reliability of bedside intensive care unit nursing assessments from 2007 to 2010
    Eduard E Vasilevskis
    Geriatric Research, Education and Clinical Center, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee, USA
    J Am Geriatr Soc 59:S249-55. 2011
  10. pmc Feasibility, efficacy, and safety of antipsychotics for intensive care unit delirium: the MIND randomized, placebo-controlled trial
    Timothy D Girard
    Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
    Crit Care Med 38:428-37. 2010

Detail Information

Publications25

  1. doi request reprint Implementing the 2013 PAD guidelines: top ten points to consider
    Brenda T Pun
    Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA
    Semin Respir Crit Care Med 34:223-35. 2013
    ..The release of any guideline should prompt reevaluation of current institutional practice standards. This manuscript uses the PAD guidelines as an example of how to approach the interprofessional work of guideline implementation...
  2. doi request reprint Delirium monitoring in the ICU: strategies for initiating and sustaining screening efforts
    Brenda T Pun
    Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University, Nashville, Tennessee, USA
    Semin Respir Crit Care Med 34:179-88. 2013
    ..Accurate detection is the first step in managing ICU patients who develop delirium in an attempt to reduce the negative sequelae of delirium in this population...
  3. ncbi request reprint The importance of diagnosing and managing ICU delirium
    Brenda T Pun
    RN, MSN, Center for Health Services Research, Vanderbilt Medical Center, Nashville, TN 37232 8300, USA
    Chest 132:624-36. 2007
    ....
  4. doi request reprint Delirium in the intensive care unit: assessment and management
    Brenda T Pun
    Vanderbilt University School of Nursing, Department of Medicine, Division of Allergy Pulmonary Critical Care Medicine, and Center for Health Services Research, 1215 21st Ave S, Nashville, TN 37232, USA
    AACN Adv Crit Care 22:225-37. 2011
    ..In addition, this article will provide an overview of recent reports concerning pharmacologic management of delirium in the intensive care unit...
  5. ncbi request reprint The sedation of critically ill adults: Part 1: Assessment. The first in a two-part series focuses on assessing sedated patients in the ICU
    Brenda T Pun
    Vanderbilt University Medical Center, Nashville, TN, USA
    Am J Nurs 107:40-8; quiz 49. 2007
    ..In August Part 2 will explore pharmacologic and nonpharmacologic management of anxiety and agitation in critically ill patients...
  6. ncbi request reprint The sedation of critically ill adults: part 2: management
    Brenda T Pun
    Vanderbilt University Medical Center in Nashville, TN, USA
    Am J Nurs 107:40-9; quiz 50. 2007
    ..The second in a two-part series focuses on the pharmacologic and nonpharmacologic management of anxiety and agitation in the ICU...
  7. pmc Long-term cognitive and psychological outcomes in the awakening and breathing controlled trial
    James C Jackson
    Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232 8300, USA
    Am J Respir Crit Care Med 182:183-91. 2010
    ..Little is known, however, of how such strategies affect long-term cognitive, psychological, and functional outcomes...
  8. pmc Delirium as a predictor of long-term cognitive impairment in survivors of critical illness
    Timothy D Girard
    Division of Allergy, Pulmonary, and Critical Care Medicine, Center for Health Services Research, Department of Medicine, Vanderbilt University School of Medicine, and Department of Medicine, Saint Thomas Hospital, Nashville, TN, USA
    Crit Care Med 38:1513-20. 2010
    ..To test the hypothesis that duration of delirium in the intensive care unit is an independent predictor of long-term cognitive impairment after critical illness requiring mechanical ventilation...
  9. pmc Delirium and sedation recognition using validated instruments: reliability of bedside intensive care unit nursing assessments from 2007 to 2010
    Eduard E Vasilevskis
    Geriatric Research, Education and Clinical Center, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee, USA
    J Am Geriatr Soc 59:S249-55. 2011
    ..To describe the reliability and sustainability of delirium and sedation measurements of bedside intensive care unit (ICU) nurses...
  10. pmc Feasibility, efficacy, and safety of antipsychotics for intensive care unit delirium: the MIND randomized, placebo-controlled trial
    Timothy D Girard
    Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
    Crit Care Med 38:428-37. 2010
    ..To demonstrate the feasibility of a placebo-controlled trial of antipsychotics for delirium in the intensive care unit and to test the hypothesis that antipsychotics would improve days alive without delirium or coma...
  11. pmc Association between endothelial dysfunction and acute brain dysfunction during critical illness
    Christopher G Hughes
    Department of Anesthesiology, Division of Critical Care, Vanderbilt University School of Medicine, 1211 21st Ave South, 526 MAB, Nashville, Tennessee 37212, USA
    Anesthesiology 118:631-9. 2013
    ..This study sought to determine whether systemic endothelial dysfunction is associated with acute brain dysfunction during critical illness...
  12. pmc Risk factors for post-traumatic stress disorder symptoms following critical illness requiring mechanical ventilation: a prospective cohort study
    Timothy D Girard
    Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232 2650, USA
    Crit Care 11:R28. 2007
    ..We sought to identify factors associated with PTSD symptoms in patients following critical illness requiring mechanical ventilation...
  13. ncbi request reprint Depression, post-traumatic stress disorder, and functional disability in survivors of critical illness in the BRAIN-ICU study: a longitudinal cohort study
    James C Jackson
    Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, USA Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN, USA Research Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN, USA Electronic address
    Lancet Respir Med 2:369-79. 2014
    ..We aimed to assess associations of age and duration of delirium with mental health and functional disabilities in this group...
  14. pmc Implementing delirium screening in the ICU: secrets to success
    Nathan E Brummel
    Geriatric Research, Education and Clinical Center, GRECC Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN, USA
    Crit Care Med 41:2196-208. 2013
    ..To review delirium screening tools available for use in the adult ICU and PICU, to review evidence-based delirium screening implementation, and to discuss common pitfalls encountered during delirium screening in the ICU...
  15. pmc A combined early cognitive and physical rehabilitation program for people who are critically ill: the activity and cognitive therapy in the intensive care unit (ACT-ICU) trial
    Nathan E Brummel
    Division of Allergy, Pulmonary, and Critical Care Medicine and Center for Health Services Research, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37212, USA
    Phys Ther 92:1580-92. 2012
    ..The feasibility of early cognitive therapy in people who are critically ill remains unknown...
  16. ncbi request reprint Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial
    Pratik P Pandharipande
    Department of Anesthesiology Division of Critical Care, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    JAMA 298:2644-53. 2007
    ..Dexmedetomidine induces sedation via different central nervous system receptors than the benzodiazepine drugs and may lower the risk of acute brain dysfunction...
  17. ncbi request reprint Delirium and its motoric subtypes: a study of 614 critically ill patients
    Josh F Peterson
    Division of General Internal Medicine, Center for Health Services Research, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    J Am Geriatr Soc 54:479-84. 2006
    ..To describe the motoric subtypes of delirium in critically ill patients and compare patients aged 65 and older with a younger cohort...
  18. doi request reprint Reducing iatrogenic risks: ICU-acquired delirium and weakness--crossing the quality chasm
    Eduard E Vasilevskis
    Division of Pulmonary Sciences and Critical Care Medicine, Veterans Affairs, Tennessee Valley Healthcare System, Vanderbilt University Medical Center, 1215 21st Ave, S, 6006 Medical Center East, NT, Nashville, TN 37232 8300, USA
    Chest 138:1224-33. 2010
    ..This evidence-based bundle of practices will build a bridge across the current quality chasm from the "front end" to the "back end" of critical care and toward improved cognitive and functional outcomes for ICU survivors...
  19. pmc Prevalence and risk factors for development of delirium in burn intensive care unit patients
    Vivek Agarwal
    Vanderbilt School of Medicine, Nashville, Tennessee, USA
    J Burn Care Res 31:706-15. 2010
    ..Exposure to benzodiazepines was an independent risk factor for delirium, whereas opiates and methadone reduced the risk of developing delirium, possibly through reduction of pain in these patients...
  20. ncbi request reprint Apolipoprotein E4 polymorphism as a genetic predisposition to delirium in critically ill patients
    E Wesley Ely
    Department of Medicine, Saint Thomas Hospital, and Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Crit Care Med 35:112-7. 2007
    ..To test for an association between apolipoprotein E (APOE) genotypes and duration of intensive care unit delirium...
  21. pmc Cognitive and physical rehabilitation of intensive care unit survivors: results of the RETURN randomized controlled pilot investigation
    James C Jackson
    Department of Medicine, Center for Health Services Research, Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    Crit Care Med 40:1088-97. 2012
    ....
  22. pmc Presence of electroencephalogram burst suppression in sedated, critically ill patients is associated with increased mortality
    Paula L Watson
    Department of Medicine, Division of Allergy, Pulmonary, and Critical Care, Vanderbilt University Medical Center, Nashville, TN, USA
    Crit Care Med 36:3171-7. 2008
    ..Burst suppression has never been studied as a potential risk factor for death in patients without a known neurologic disorder or injury...
  23. doi request reprint Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial
    Timothy D Girard
    Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232 8300, USA
    Lancet 371:126-34. 2008
    ..Our aim was to assess a protocol that paired spontaneous awakening trials (SATs)-ie, daily interruption of sedatives-with spontaneous breathing trials (SBTs)...
  24. pmc Delirium and sedation in the intensive care unit: survey of behaviors and attitudes of 1384 healthcare professionals
    Rina P Patel
    School of Medicine RPP, Vanderbilt University School of Medicine, Nashville, TN, USA
    Crit Care Med 37:825-32. 2009
    ..Our objective was to assess beliefs and practices regarding ICU delirium and sedation management...
  25. pmc Intensive care unit delirium is an independent predictor of longer hospital stay: a prospective analysis of 261 non-ventilated patients
    Jason W W Thomason
    Division of Allergy Pulmonary Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
    Crit Care 9:R375-81. 2005
    ..The study objective was to determine the relationship between delirium and outcomes among non-ventilated ICU patients...