T Pincus

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. ncbi An index of the three core data set patient questionnaire measures distinguishes efficacy of active treatment from that of placebo as effectively as the American College of Rheumatology 20% response criteria (ACR20) or the Disease Activity Score (DAS) in
    T Pincus
    Division of Rheumatology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Arthritis Rheum 48:625-30. 2003
  2. ncbi A randomized, double-blind, crossover clinical trial of diclofenac plus misoprostol versus acetaminophen in patients with osteoarthritis of the hip or knee
    T Pincus
    Division of Rheumatology and Immunology, Vanderbilt University, Nashville, Tennessee 37232-4500, USA
    Arthritis Rheum 44:1587-98. 2001
  3. ncbi Databases of patients with early rheumatoid arthritis in the USA
    T Sokka
    Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Clin Exp Rheumatol 21:S146-53. 2003
  4. ncbi Work disability in early rheumatoid arthritis: higher rates but better clinical status in Finland compared with the US
    C P Chung
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-4500, USA
    Ann Rheum Dis 65:1653-7. 2006
  5. ncbi Declines in number of tender and swollen joints in patients with rheumatoid arthritis seen in standard care in 1985 versus 2001: possible considerations for revision of inclusion criteria for clinical trials
    T Pincus
    Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA, and Jyväskylä Central Hospital, Finland
    Ann Rheum Dis 65:878-83. 2006
  6. ncbi Preference for nonsteroidal antiinflammatory drugs versus acetaminophen and concomitant use of both types of drugs in patients with osteoarthritis
    T Pincus
    Division of Rheumatology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    J Rheumatol 27:1020-7. 2000
  7. ncbi Are American College of Rheumatology 50% response criteria superior to 20% criteria in distinguishing active aggressive treatment in rheumatoid arthritis clinical trials reported since 1997? A meta-analysis of discriminant capacities
    C P Chung
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennessee 37232 4500, USA
    Ann Rheum Dis 65:1602-7. 2006
  8. ncbi A proposed 30-45 minute 4 page standard protocol to evaluate rheumatoid arthritis (SPERA) that includes measures of inflammatory activity, joint damage, and longterm outcomes
    T Pincus
    Vanderbilt University School of Medicine, Department of Medicine, Nashville, TN 37232 4500, USA
    J Rheumatol 26:473-80. 1999
  9. ncbi A proposed approach to recognise "near-remission" quantitatively without formal joint counts or laboratory tests: a patient self-report questionnaire routine assessment of patient index data (RAPID) score as a guide to a "continuous quality
    T Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 4500, USA
    Clin Exp Rheumatol 24:S-60-5; quiz S-66-73. 2006
  10. ncbi Methotrexate as the "anchor drug" for the treatment of early rheumatoid arthritis
    T Pincus
    Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
    Clin Exp Rheumatol 21:S179-85. 2003

Detail Information

Publications55

  1. ncbi An index of the three core data set patient questionnaire measures distinguishes efficacy of active treatment from that of placebo as effectively as the American College of Rheumatology 20% response criteria (ACR20) or the Disease Activity Score (DAS) in
    T Pincus
    Division of Rheumatology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Arthritis Rheum 48:625-30. 2003
    ....
  2. ncbi A randomized, double-blind, crossover clinical trial of diclofenac plus misoprostol versus acetaminophen in patients with osteoarthritis of the hip or knee
    T Pincus
    Division of Rheumatology and Immunology, Vanderbilt University, Nashville, Tennessee 37232-4500, USA
    Arthritis Rheum 44:1587-98. 2001
    ..Acetaminophen was associated with fewer adverse events...
  3. ncbi Databases of patients with early rheumatoid arthritis in the USA
    T Sokka
    Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Clin Exp Rheumatol 21:S146-53. 2003
    ..Further observation of recent cohorts of patients with early RA over the next decade should be informative regarding whether aggressive intervention strategies and new DMARDs and biologic agents lead to improved long-term outcomes...
  4. ncbi Work disability in early rheumatoid arthritis: higher rates but better clinical status in Finland compared with the US
    C P Chung
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-4500, USA
    Ann Rheum Dis 65:1653-7. 2006
    ..Higher work disability rates with better clinical status was seen in the Finnish early rheumatoid arthritis cohort than in the US cohort...
  5. ncbi Declines in number of tender and swollen joints in patients with rheumatoid arthritis seen in standard care in 1985 versus 2001: possible considerations for revision of inclusion criteria for clinical trials
    T Pincus
    Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA, and Jyväskylä Central Hospital, Finland
    Ann Rheum Dis 65:878-83. 2006
    ....
  6. ncbi Preference for nonsteroidal antiinflammatory drugs versus acetaminophen and concomitant use of both types of drugs in patients with osteoarthritis
    T Pincus
    Division of Rheumatology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    J Rheumatol 27:1020-7. 2000
    ..To analyze results of treatment of osteoarthritis (OA) with acetaminophen and the nonsteroidal antiinflammatory drugs (NSAID) through a patient survey...
  7. ncbi Are American College of Rheumatology 50% response criteria superior to 20% criteria in distinguishing active aggressive treatment in rheumatoid arthritis clinical trials reported since 1997? A meta-analysis of discriminant capacities
    C P Chung
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennessee 37232 4500, USA
    Ann Rheum Dis 65:1602-7. 2006
    ....
  8. ncbi A proposed 30-45 minute 4 page standard protocol to evaluate rheumatoid arthritis (SPERA) that includes measures of inflammatory activity, joint damage, and longterm outcomes
    T Pincus
    Vanderbilt University School of Medicine, Department of Medicine, Nashville, TN 37232 4500, USA
    J Rheumatol 26:473-80. 1999
    ..The SPERA is feasible to acquire most known relevant measures of activity, damage, and outcomes in RA in 30-45 min in usual clinical settings, to provide a complete database for analyses of longterm outcomes...
  9. ncbi A proposed approach to recognise "near-remission" quantitatively without formal joint counts or laboratory tests: a patient self-report questionnaire routine assessment of patient index data (RAPID) score as a guide to a "continuous quality
    T Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 4500, USA
    Clin Exp Rheumatol 24:S-60-5; quiz S-66-73. 2006
    ....
  10. ncbi Methotrexate as the "anchor drug" for the treatment of early rheumatoid arthritis
    T Pincus
    Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
    Clin Exp Rheumatol 21:S179-85. 2003
    ..These data establish that methotrexate is the anchor drug and probably should be the first DMARD used in the majority of patients with RA at this time...
  11. ncbi Underestimation of the efficacy, effectiveness, tolerability, and safety of weekly low-dose methotrexate in information presented to physicians and patients
    T Pincus
    Department of Medicine, Division of Rheumatology, New York University School of Medicine and NYU Hospital for Joint Diseases, New York, NY 10003, USA
    Clin Exp Rheumatol 28:S68-79. 2010
    ....
  12. ncbi Patient Preference for Placebo, Acetaminophen (paracetamol) or Celecoxib Efficacy Studies (PACES): two randomised, double blind, placebo controlled, crossover clinical trials in patients with knee or hip osteoarthritis
    T Pincus
    Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
    Ann Rheum Dis 63:931-9. 2004
    ..However, survey and clinical trial data indicate greater efficacy for non-steroidal anti-inflammatory drugs and cyclo-oxygenase-2 specific inhibitors...
  13. ncbi A 3-page standard protocol to evaluate rheumatoid arthritis (SPERA): efficient capture of essential data for clinical trials and observational studies
    T Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Vanderbilt University School of Medicine, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
    Clin Exp Rheumatol 23:S114-9. 2005
    ....
  14. ncbi An Early Rheumatoid Arthritis Treatment Evaluation Registry (ERATER) in the United States
    T Sokka
    Vanderbilt University Medical Center, Vanderbilt University School of Medicine, 203 Oxford House, Box 5, Nashville, TN 37232-4500, USA
    Clin Exp Rheumatol 23:S178-81. 2005
    ..This essay describes the background regarding the identification of the cohort, methods for data collection, and observations to date...
  15. ncbi Uniform databases in early arthritis: specific measures to complement classification criteria and indices of clinical change
    T Pincus
    Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Clin Exp Rheumatol 21:S79-88. 2003
    ..However, the availability of an infrastructure of standard data in all RA databases would enhance clinical research in early RA...
  16. ncbi Rheumatology function tests: quantitative physical measures to monitor morbidity and predict mortality in patients with rheumatic diseases
    T Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Vanderbilt University School of Medicine, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
    Clin Exp Rheumatol 23:S85-9. 2005
    ..Physical measures of function also were significant predictors of mortality in two cohorts of patients with RA, one monitored between 1973 and 1988, and a second between 1985 and 1990...
  17. ncbi Quantitative joint assessment in rheumatoid arthritis
    T Sokka
    Vanderbilt University Medical Center, Vanderbilt University School of Medicine, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
    Clin Exp Rheumatol 23:S58-62. 2005
    ..This article reviews selected methods for the performance of joint counts, with discussion of their advantages and limitations in the assessment of patients with rheumatoid arthritis...
  18. ncbi Quantitative documentation of benefit/risk of new therapies for rheumatoid arthritis: patient questionnaires as an optimal measure in standard care
    T Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232-4500, USA
    Clin Exp Rheumatol 22:S26-33. 2004
    ..We suggest that quantitative measurement may be incorporated into standard clinical care most easily and effectively by asking each patient to complete a simple 1-page questionnaire at each visit to a rheumatologist...
  19. ncbi Relative versus absolute goals of therapies for RA: ACR 20 or ACR 50 responses versus target values for "near remission" of DAS or single measures
    T Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232-4500, USA
    Clin Exp Rheumatol 22:S50-6. 2004
    ..These findings suggest that absolute targets, including remission, may be realistic contemporary goals, with aggressive treatment strategies and more effective DMARDs and biologic agents...
  20. ncbi How can the risk of long-term consequences of rheumatoid arthritis be reduced?
    T Pincus
    Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, 203 Oxford House, Nashville, TN 37232, USA
    Best Pract Res Clin Rheumatol 15:139-70. 2001
    ..Patient self-report questionnaires appear to provide the least expensive and most effective measures toward this goal...
  21. ncbi Complexities in defining remission in rheumatic diseases
    T Pincus
    Division of Rheumatology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232 4500, USA
    Clin Exp Rheumatol 24:S-1-6. 2006
    ..Thus, the subject of remission remains under active discussion in the rheumatology community...
  22. ncbi Educational program for physicians to reduce use of non-steroidal anti-inflammatory drugs among community-dwelling elderly persons: a randomized controlled trial
    W A Ray
    Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Med Care 39:425-35. 2001
    ..Because NSAIDs frequently cause serious gastrointestinal (GI) and other complications among elderly patients, expert guidelines for osteoarthritis recommend acetaminophen-based regimens, which are safer and often as effective as NSAIDs...
  23. ncbi Should contemporary rheumatoid arthritis clinical trials be more like standard patient care and vice versa?
    T Pincus
    Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
    Ann Rheum Dis 63:ii32-ii39. 2004
    ....
  24. ncbi Benefit/risk of therapies for rheumatoid arthritis: underestimation of the "side effects" or risks of RA leads to underestimation of the benefit/risk of therapies
    T Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232-4500, USA
    Clin Exp Rheumatol 22:S2-11. 2004
    ..It appears that the benefit/risk ratio of therapies for RA has increased substantially over the last two decades, and the outlook for patients with RA is much better at this time than in previous years...
  25. ncbi The American College of Rheumatology (ACR) Core Data Set and derivative "patient only" indices to assess rheumatoid arthritis
    T Pincus
    Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
    Clin Exp Rheumatol 23:S109-13. 2005
    ....
  26. ncbi Quantitative target values of predictors of mortality in rheumatoid arthritis as possible goals for therapeutic interventions: an alternative approach to remission or ACR20 responses?
    T Pincus
    Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 4500, USA
    J Rheumatol 28:1723-34. 2001
    ..Better control of quantitative markers that predict early mortality could provide a valuable approach to improving outcomes in RA...
  27. ncbi Partial control of Core Data Set measures and Disease Activity Score (DAS) measures of inflammation does not prevent long-term joint damage: evidence from longitudinal observations over 5-20 years
    T Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232-4500, USA
    Clin Exp Rheumatol 20:S42-7. 2002
    ....
  28. ncbi Development of a multi-dimensional health assessment questionnaire (MDHAQ) for the infrastructure of standard clinical care
    T Pincus
    Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
    Clin Exp Rheumatol 23:S19-28. 2005
    ..The MDHAQ can be used in the infrastructure of rheumatology care to include quantitative data in standard care of all patients with all rheumatic diseases...
  29. ncbi A historical perspective concerning population-based and clinical studies of early arthritis and early rheumatoid arthritis
    T Sokka
    Vanderbilt University Medical Center, Nashville, TN, USA
    Clin Exp Rheumatol 21:S5-14. 2003
    ..These studies and others described elsewhere in this supplement have contributed to the foundations for the clinical approach to early arthritis in the 21st century...
  30. ncbi Most visits of most patients with rheumatoid arthritis to most rheumatologists do not include a formal quantitative joint count
    T Pincus
    Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
    Ann Rheum Dis 65:820-2. 2006
    ..To ask rheumatologists about the likelihood of performing a formal joint count at each visit of a patient with rheumatoid arthritis (RA) in standard clinical care...
  31. ncbi How useful are combinations of blood tests in "rheumatic panels" in diagnosis of rheumatic diseases?
    M J Lichtenstein
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232
    J Gen Intern Med 3:435-42. 1988
    ..A careful history and physical examination along with serial ordering of a few selected tests appear optimal to establish a clinical diagnosis of a rheumatic disease...
  32. ncbi Clinical evidence for osteoarthritis as an inflammatory disease
    T Pincus
    Division of Rheumatology, Vanderbilt University Medical Center, 203 Oxford House, Box 5, Nashville, TN 37232-4500, USA
    Curr Rheumatol Rep 3:524-34. 2001
    ..A recent crossover clinical trial indicated significantly greater efficacy of the NSAID, diclofenac/misoprostol, versus acetaminophen for most patients with OA...
  33. ncbi Eosinophilia-myalgia syndrome: patient status 2-4 years after onset
    T Pincus
    Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    J Rheumatol Suppl 46:19-24; discussion 24-5. 1996
    ....
  34. ncbi Complexities in the quantitative assessment of patients with rheumatic diseases in clinical trials and clinical care
    T Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Vanderbilt University School of Medicine, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
    Clin Exp Rheumatol 23:S1-9. 2005
    ....
  35. ncbi Evidence from clinical trials and long-term observational studies that disease-modifying anti-rheumatic drugs slow radiographic progression in rheumatoid arthritis: updating a 1983 review
    T Pincus
    Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University School of Medicine, 203 Oxford House, Nashville, TN 37232-4500, USA
    Rheumatology (Oxford) 41:1346-56. 2002
    ..Documentation of improved long-term outcomes requires long-term observational data over 5-20 yr to supplement data from randomized controlled clinical trials over 6-24 months...
  36. ncbi Most people over age 50 in the general population do not meet ACR remission criteria or OMERACT minimal disease activity criteria for rheumatoid arthritis
    T Sokka
    Jyvaskyla Central Hospital, 40620 Jyvaskyla, Finland
    Rheumatology (Oxford) 46:1020-3. 2007
    ....
  37. ncbi Should aggressive therapy for rheumatoid arthritis require early use of weekly low-dose methotrexate, as the first disease-modifying anti-rheumatic drug in most patients?
    T Pincus
    Rheumatology (Oxford) 45:497-9. 2006
  38. ncbi Quantitative measurement of patient status in the regular care of patients with rheumatic diseases over 25 years as a continuous quality improvement activity, rather than traditional research
    T Pincus
    New York University School of Medicine and NYU Hospital for Joint Diseases, New York, NY 10003, USA
    Clin Exp Rheumatol 25:69-81. 2007
    ..The latter cycles remain under study as ongoing CQI activities...
  39. ncbi Assessment of quality of rheumatoid arthritis care requires joint count and/or patient questionnaire data not found in a usual medical record: examples from studies of premature mortality, changes in clinical status between 1985 and 2000, and a QUEST-RA g
    T Sokka
    Jyvaskyla Central Hospital, Jyvaskyla, Finland
    Clin Exp Rheumatol 25:86-97. 2007
    ....
  40. ncbi An index of only patient-reported outcome measures, routine assessment of patient index data 3 (RAPID3), in two abatacept clinical trials: similar results to disease activity score (DAS28) and other RAPID indices that include physician-reported measures
    T Pincus
    NYU Hospital for Joint Diseases, 301 East 17th Street, New York, NY 10003, USA
    Rheumatology (Oxford) 47:345-9. 2008
    ....
  41. ncbi Reporting disease activity in clinical trials of patients with rheumatoid arthritis: EULAR/ACR collaborative recommendations
    D Aletaha
    Division of Rheumatology, Medical University of Vienna, Vienna, Austria
    Ann Rheum Dis 67:1360-4. 2008
    ..To make recommendations on how to report disease activity in clinical trials of rheumatoid arthritis (RA) endorsed by the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR)...
  42. ncbi Markers for work disability in rheumatoid arthritis
    T Sokka
    Jyvaskyla Central Hospital, Department of Medicine, Finland
    J Rheumatol 28:1718-22. 2001
    ..Improved work disability outcomes in RA will require attention to social, economic, and political issues, and wider physician and public education concerning RA, in addition to improved medical management of disease...
  43. ncbi How aggressive should initial therapy for rheumatoid arthritis be?
    T Pincus
    Rheumatology (Oxford) 44:133-4; author reply 135-6. 2005
  44. ncbi Long term safety of methotrexate in routine clinical care: discontinuation is unusual and rarely the result of laboratory abnormalities
    Y Yazici
    Brooklyn Heights Arthritis Associates, Long Island College Hospital, Brooklyn, NY, USA
    Ann Rheum Dis 64:207-11. 2005
    ..To analyse patients with rheumatoid arthritis, treated with methotrexate in a weekly academic rheumatology clinic over 13 years, for continuation of courses and reasons for discontinuation...
  45. ncbi Do rheumatology cost-effectiveness analyses make sense?
    F Wolfe
    Rheumatology (Oxford) 43:4-6. 2004
  46. ncbi A proposed treatment algorithm for rheumatoid arthritis: aggressive therapy, methotrexate, and quantitative measures
    J S Smolen
    University of Vienna and Krankenhaus Lainz, Division of Rheumatology, Internal Medicine III, Waehringer Guertel 18-20, A-1090 Vienna, Austria
    Clin Exp Rheumatol 21:S209-10. 2003
  47. ncbi Early arthritis. Introduction
    T Pincus
    Clin Exp Rheumatol 21:S1. 2003
  48. ncbi Further clues to recognition of patients with fibromyalgia from a simple 2-page patient multidimensional health assessment questionnaire (MDHAQ)
    D A DeWalt
    University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA
    Clin Exp Rheumatol 22:453-61. 2004
    ..CONCLUSION: A simple 1-page, 2-sided patient questionnaire provides quantitative information which may contribute to identify patients with fibromyalgia, including patients with RA who may also have coexistent fibromyalgia...
  49. ncbi Reporting disease activity in clinical trials of patients with rheumatoid arthritis: EULAR/ACR collaborative recommendations
    D Aletaha
    Medical University of Vienna, Vienna, Austria
    Arthritis Rheum 59:1371-7. 2008
    ..To make recommendations on how to report disease activity in clinical trials of rheumatoid arthritis (RA) endorsed by the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR)...
  50. ncbi Disparities in health according to socioeconomic status
    T Pincus
    Ann Rheum Dis 64:795; author reply 795. 2005
  51. ncbi Novel anti-rheumatic therapies challenge old views on ankylosing spondylitis and other spondyloarthritides
    J Braun
    Rheumazentrum Ruhrgebiet, St. Josefs-Krankenhaus, Herne, Germany
    Clin Exp Rheumatol 20:S1-2. 2002
  52. ncbi Chronic musculoskeletal pain rarely presents in a single body site: results from a UK population study
    D Carnes
    Centre for Health Sciences, Barts and The London, Queen Mary School of Medicine and Dentistry, 2 Newark St, London, E1 2AT, UK
    Rheumatology (Oxford) 46:1168-70. 2007
    ..To investigate the frequency and health impact of chronic multi-site musculoskeletal pain, in a representative UK sample...
  53. ncbi Mortality, course of disease and prognosis of patients with ankylosing spondylitis
    J Braun
    Rheumazentrum Ruhrgebiet, St. Josefs-Krankenhaus, Herne, Germany
    Clin Exp Rheumatol 20:S16-22. 2002
    ..This therapy has been largely abandoned nowadays. Elder rheumatologists report however that the clinical improvement of irradiated patients has been partly impressive...
  54. ncbi A genomewide screen in multiplex rheumatoid arthritis families suggests genetic overlap with other autoimmune diseases
    D Jawaheer
    Division of Biology and Human Genetics, North Shore University Hospital, Manhasset, NY 11030, USA
    Am J Hum Genet 68:927-36. 2001
    ..Therefore, genes in the HLA complex play a major role in RA susceptibility, but several other regions also contribute significantly to overall genetic risk...
  55. ncbi Prevalence and comparative troublesomeness by age of musculoskeletal pain in different body locations
    S Parsons
    Centre for Health Sciences, Barts and The London, Queen Mary s School of Medicine and Dentistry, UK
    Fam Pract 24:308-16. 2007
    ..Chronic pain has large health care costs and a major impact on the health of those affected. Few studies have also considered the severity of pain in different parts of the body across all age groups...