Affiliation: Vanderbilt University
- Fluconazole for empiric antifungal therapy in cancer patients with fever and neutropeniaDonghui T Yu
Division of General Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
BMC Infect Dis 6:173. 2006..Our objective was to assess the frequency and resource utilization associated with treatment failure in cancer patients given empiric fluconazole antifungal therapy in routine inpatient care...
- Physicians' response to guided geriatric dosing: initial results from a randomized trialJosh F Peterson
Vanderbilt University School of Medicine, Department of Biomedical Informatics, Nashville, TN, USA
Stud Health Technol Inform 129:1037-40. 2007..0,4.0]) than the control group (median 3.0 interquartile range [1.5,5.0], p<0.001). While physicians selected the recommended dose less than a third of the time, guided geriatric dosing modestly improved compliance with guidelines...
- Guided prescription of psychotropic medications for geriatric inpatientsJosh F Peterson
Division of General Internal Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
Arch Intern Med 165:802-7. 2005..Inappropriate use or excessive dosing of psychotropic medications in the elderly is common and can lead to a variety of adverse drug events including falls, oversedation, and cognitive impairment...
- Delirium and its motoric subtypes: a study of 614 critically ill patientsJosh F Peterson
Division of General Internal Medicine, Center for Health Services Research, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
J Am Geriatr Soc 54:479-84. 2006..To describe the motoric subtypes of delirium in critically ill patients and compare patients aged 65 and older with a younger cohort...
- Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patientsPratik Pandharipande
Department of Anesthesia Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
Anesthesiology 104:21-6. 2006..Sedative and analgesic medications relieve anxiety and pain but may contribute to patients' transitioning into delirium...
- Identifying QT prolongation from ECG impressions using natural language processing and negation detectionJoshua C Denny
Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37232, USA
Stud Health Technol Inform 129:1283-8. 2007..We conclude that a natural language processing system can effectively identify QT prolongation and other cardiac diagnoses from ECG impressions for potential decision support and clinical research...
- Evaluation of a method to identify and categorize section headers in clinical documentsJoshua C Denny
Department of Biomedical Informatics, Vanderbilt UniversitySchool of Medicine, Eskind Biomedical Library, Room 442, 2209 Garland Ave, Nashville TN 37232, USA
J Am Med Inform Assoc 16:806-15. 2009..quot; The authors designed and evaluated an algorithm ("SecTag") to identify both labeled and unlabeled (implied) note section headers in "history and physical examination" documents ("H&P notes")...
- Development of inpatient risk stratification models of acute kidney injury for use in electronic health recordsMichael E Matheny
Geriatric Research Education Clinical Center, Tennessee Valley Health System, Veterans Health Administration, Nashville, TN, USA
Med Decis Making 30:639-50. 2010....
- Extracting timing and status descriptors for colonoscopy testing from electronic medical recordsJoshua C Denny
Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee, USA
J Am Med Inform Assoc 17:383-8. 2010..Further investigations must validate extension of NLP approaches for other types of CRC screening applications...
- A computerized provider order entry intervention for medication safety during acute kidney injury: a quality improvement reportAllison B McCoy
Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA
Am J Kidney Dis 56:832-41. 2010..Frequently, prescribers fail to account for changing kidney function when prescribing medications. We evaluated the use of a computerized provider order entry intervention to improve medication management during acute kidney injury...
- Medication administration discrepancies persist despite electronic orderingFern Fitzhenry
Department of Biomedical Informatics, Vanderbilt University Medical Center, 2525 West End Avenue, Nashville, TN 37203, USA
J Am Med Inform Assoc 14:756-64. 2007....
- Intensive care unit delirium is an independent predictor of longer hospital stay: a prospective analysis of 261 non-ventilated patientsJason W W Thomason
Division of Allergy/Pulmonary/Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
Crit Care 9:R375-81. 2005..55-2.98, p = 0.58). CONCLUSION: Delirium occurred in nearly half of the non-ventilated ICU patients in this cohort. Even after adjustment for relevant covariates, delirium was found to be an independent predictor of longer hospital stay...
- Large-scale implementation of sedation and delirium monitoring in the intensive care unit: a report from two medical centersBrenda Truman Pun
Department of Medicine, Division of Allergy Pulmonary Critical Care Medicine, and Center for Health Services Research, Vanderbilt University School of Medicine, Vanderbilt University School of Nursing, Nashville, TN 37232, USA
Crit Care Med 33:1199-205. 2005....
- Elevated urinary IL-18 levels at the time of ICU admission predict adverse clinical outcomesEdward D Siew
Division of Nephrology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
Clin J Am Soc Nephrol 5:1497-505. 2010..Its ability to predict AKI and provide prognostic information in broadly selected, critically ill adults remains unknown...
- Commonly used surrogates for baseline renal function affect the classification and prognosis of acute kidney injuryEdward D Siew
Division of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
Kidney Int 77:536-42. 2010..Our study found that commonly used surrogates for baseline serum creatinine result in bi-directional misclassification of the incidence and prognosis of acute kidney injury in a hospital setting...
- Electronically screening discharge summaries for adverse medical eventsHarvey J Murff
Division of General Internal Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA
J Am Med Inform Assoc 10:339-50. 2003..Nonetheless, computerized clinical narrative screening methods could potentially offer researchers and quality managers a means to routinely detect adverse events...
- Adverse drug events occurring following hospital dischargeAlan J Forster
Division of General Internal Medicine and Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada
J Gen Intern Med 20:317-23. 2005..To describe the incidence of adverse drug events (ADEs), preventable ADEs, and ameliorable ADEs occurring after hospital discharge and their associated risk factors...
- The incidence and severity of adverse events affecting patients after discharge from the hospitalAlan J Forster
University of Ottawa, F654-1053 Carling Avenue, Ottawa, Ontario K1Y 4E9, Canada
Ann Intern Med 138:161-7. 2003..CONCLUSION: Adverse events occurred frequently in the peridischarge period, and many could potentially have been prevented or ameliorated with simple strategies...
- Information Systems for Detecting and Managing Acute Kidney InjuryJosh F Peterson; Fiscal Year: 2010..The goal is to prevent AKI progression and the associated complications of hypokalemia, acidemia, and medication toxicity. ..