Christopher M Olsen

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. ncbi Microarray analysis reveals distinctive signaling between the bed nucleus of the stria terminalis, nucleus accumbens, and dorsal striatum
    Christopher M Olsen
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232 0615, USA
    Physiol Genomics 32:283-98. 2008
  2. pmc Natural rewards, neuroplasticity, and non-drug addictions
    Christopher M Olsen
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232 0615, USA
    Neuropharmacology 61:1109-22. 2011
  3. ncbi A method for single-session cocaine self-administration in the mouse
    Christopher M Olsen
    Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN 37232 0615, USA
    Psychopharmacology (Berl) 187:13-21. 2006
  4. pmc Operant sensation seeking requires metabotropic glutamate receptor 5 (mGluR5)
    Christopher M Olsen
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
    PLoS ONE 5:e15085. 2010
  5. pmc Operant sensation seeking engages similar neural substrates to operant drug seeking in C57 mice
    Christopher M Olsen
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232 0615, USA
    Neuropsychopharmacology 34:1685-94. 2009
  6. ncbi Extracellular-signal regulated kinase 1-dependent metabotropic glutamate receptor 5-induced long-term depression in the bed nucleus of the stria terminalis is disrupted by cocaine administration
    Brad A Grueter
    Department of Molecular Physiology, Center for Molecular Neuroscience, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Neurosci 26:3210-9. 2006
  7. ncbi Cocaine self-administration reduces excitatory responses in the mouse nucleus accumbens shell
    Nicole L Schramm-Sapyta
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232 0615, USA
    Neuropsychopharmacology 31:1444-51. 2006
  8. pmc Stimulus dynamics increase the self-administration of compound visual and auditory stimuli
    Christopher M Olsen
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232 0615, USA
    Neurosci Lett 511:8-11. 2012
  9. ncbi Prefrontal cortex D1 modulation of the reinforcing properties of cocaine
    Christopher M Olsen
    Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Brain Res 1075:229-35. 2006
  10. pmc Experience-dependent effects of cocaine self-administration/conditioning on prefrontal and accumbens dopamine responses
    Aiko Ikegami
    College of Pharmacy, Division of Pharmacology and Toxicology, University of Texas, Austin, TX 78712 1074, USA
    Behav Neurosci 121:389-400. 2007

Collaborators

Detail Information

Publications12

  1. ncbi Microarray analysis reveals distinctive signaling between the bed nucleus of the stria terminalis, nucleus accumbens, and dorsal striatum
    Christopher M Olsen
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232 0615, USA
    Physiol Genomics 32:283-98. 2008
    ..Furthermore, these studies provide a framework for future mouse-mouse comparisons of transcriptional profiles after behavioral/pharmacological manipulation...
  2. pmc Natural rewards, neuroplasticity, and non-drug addictions
    Christopher M Olsen
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232 0615, USA
    Neuropharmacology 61:1109-22. 2011
    ....
  3. ncbi A method for single-session cocaine self-administration in the mouse
    Christopher M Olsen
    Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN 37232 0615, USA
    Psychopharmacology (Berl) 187:13-21. 2006
    ..With the spectrum of genetically modified mice available, there is a need for well-designed drug self-administration studies tailored for rapid completion of studies in mice...
  4. pmc Operant sensation seeking requires metabotropic glutamate receptor 5 (mGluR5)
    Christopher M Olsen
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
    PLoS ONE 5:e15085. 2010
    ..In total, these data demonstrate a key role for mGluR5 in OSS, indicating an important role for this receptor in reinforcement-based behavior...
  5. pmc Operant sensation seeking engages similar neural substrates to operant drug seeking in C57 mice
    Christopher M Olsen
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232 0615, USA
    Neuropsychopharmacology 34:1685-94. 2009
    ..OSS may have predictive validity for screening compounds for use in the treatment of drug addiction. In addition, we also discuss the potential relevance of this animal model to the field of behavioral addictions...
  6. ncbi Extracellular-signal regulated kinase 1-dependent metabotropic glutamate receptor 5-induced long-term depression in the bed nucleus of the stria terminalis is disrupted by cocaine administration
    Brad A Grueter
    Department of Molecular Physiology, Center for Molecular Neuroscience, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Neurosci 26:3210-9. 2006
    ....
  7. ncbi Cocaine self-administration reduces excitatory responses in the mouse nucleus accumbens shell
    Nicole L Schramm-Sapyta
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232 0615, USA
    Neuropsychopharmacology 31:1444-51. 2006
    ..This reduction in glutamatergic signaling may be one mechanism by which cocaine exerts its long-term behavioral effects...
  8. pmc Stimulus dynamics increase the self-administration of compound visual and auditory stimuli
    Christopher M Olsen
    Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232 0615, USA
    Neurosci Lett 511:8-11. 2012
    ..We found that stimulus variability increased the amount of operant responding exhibited by mice, a phenomenon observed under both fixed- and progressive-ratio schedules...
  9. ncbi Prefrontal cortex D1 modulation of the reinforcing properties of cocaine
    Christopher M Olsen
    Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Brain Res 1075:229-35. 2006
    ..Current findings demonstrate that transient changes in PFC DA neurotransmission can specifically influence reinforced behaviors without affecting overall behavioral activation...
  10. pmc Experience-dependent effects of cocaine self-administration/conditioning on prefrontal and accumbens dopamine responses
    Aiko Ikegami
    College of Pharmacy, Division of Pharmacology and Toxicology, University of Texas, Austin, TX 78712 1074, USA
    Behav Neurosci 121:389-400. 2007
    ....
  11. ncbi Chronic D1 agonist and ethanol coadministration facilitate ethanol-mediated behaviors
    Manoranjan S D'Souza
    Division of Pharmacology and Toxicology, College of Pharmacy, University of Texas, 1 University Station A1915, Austin, TX 78712 0125, USA
    Pharmacol Biochem Behav 76:335-42. 2003
    ..These findings suggest that chronic D1 receptor activation combined with EtOH administration alters neural responsiveness to EtOH and support the notion that D1 activation is important to EtOH reward...
  12. ncbi Intravenous ethanol/cocaine self-administration initiates high intake of intravenous ethanol alone
    Aiko Ikegami
    College of Pharmacy, Division of Pharmacology Toxicology, PHR 5 224, The University of Texas, Austin, TX 78712 1074, USA
    Pharmacol Biochem Behav 72:787-94. 2002
    ..Further studies utilizing intravenous EtOH self-administration will allow identification of various long-term behavioral and neural consequences of voluntary high EtOH intake...