Nagathihalli S Nagaraj

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. doi request reprint Integrating genomics and proteomics-oriented biomarkers to comprehend lung cancer
    Nagathihalli S Nagaraj
    Vanderbilt University School of Medicine, Division of Surgical Oncology, Department of Surgery, 1161 21st Ave S, D2300 MCN, Nashville, TN 37232, USA 1 615 509 1565, 1 615 322 6174
    Expert Opin Med Diagn 3:167-80. 2009
  2. doi request reprint RAD51 as a potential biomarker and therapeutic target for pancreatic cancer
    Nagaraj S Nagathihalli
    Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232 6860, USA
    Biochim Biophys Acta 1816:209-18. 2011
  3. ncbi request reprint Src-mediated regulation of E-cadherin and EMT in pancreatic cancer
    Nagaraj S Nagathihalli
    Division of Surgical Oncology, Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232 6860, USA
    Front Biosci (Landmark Ed) 17:2059-69. 2012
  4. doi request reprint Evolving 'omics' technologies for diagnostics of head and neck cancer
    Nagathihalli S Nagaraj
    Department of Surgery, Division of Surgical Oncology, Vanderbilt University School of Medicine, 21st Ave S, Nashville, TN 37232, USA
    Brief Funct Genomic Proteomic 8:49-59. 2009
  5. doi request reprint Using genomics to develop novel antibacterial therapeutics
    Nagathihalli S Nagaraj
    Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Crit Rev Microbiol 36:340-8. 2010
  6. doi request reprint Proteomics: a strategy to understand the novel targets in protein misfolding and cancer therapy
    Nagathihalli S Nagaraj
    Department of Surgery, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Expert Rev Proteomics 7:613-23. 2010
  7. doi request reprint Diallyl disulfide causes caspase-dependent apoptosis in human cancer cells through a Bax-triggered mitochondrial pathway
    Nagathihalli S Nagaraj
    Division of Surgical Oncology, Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    J Nutr Biochem 21:405-12. 2010
  8. pmc Combined blockade of Src kinase and epidermal growth factor receptor with gemcitabine overcomes STAT3-mediated resistance of inhibition of pancreatic tumor growth
    Nagathihalli S Nagaraj
    Department of Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Clin Cancer Res 17:483-93. 2011
  9. pmc Targeted inhibition of SRC kinase signaling attenuates pancreatic tumorigenesis
    Nagathihalli S Nagaraj
    Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN, USA
    Mol Cancer Ther 9:2322-32. 2010
  10. pmc Targeting the transforming growth factor-beta signaling pathway in human cancer
    Nagathihalli S Nagaraj
    Vanderbilt University School of Medicine, Vanderbilt Ingram Cancer Center, Department of Surgery, Nashville, TN 37232, USA
    Expert Opin Investig Drugs 19:77-91. 2010

Collaborators

Detail Information

Publications11

  1. doi request reprint Integrating genomics and proteomics-oriented biomarkers to comprehend lung cancer
    Nagathihalli S Nagaraj
    Vanderbilt University School of Medicine, Division of Surgical Oncology, Department of Surgery, 1161 21st Ave S, D2300 MCN, Nashville, TN 37232, USA 1 615 509 1565, 1 615 322 6174
    Expert Opin Med Diagn 3:167-80. 2009
    ..Here the potential benefits and pitfalls of these methodologies are reviewed for the faster discovery of therapeutically valuable biomarkers for lung cancer...
  2. doi request reprint RAD51 as a potential biomarker and therapeutic target for pancreatic cancer
    Nagaraj S Nagathihalli
    Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232 6860, USA
    Biochim Biophys Acta 1816:209-18. 2011
    ..Finally, we speculate that targeting RAD51 in pancreatic cancer cells may be a novel approach for the treatment of pancreatic cancer...
  3. ncbi request reprint Src-mediated regulation of E-cadherin and EMT in pancreatic cancer
    Nagaraj S Nagathihalli
    Division of Surgical Oncology, Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232 6860, USA
    Front Biosci (Landmark Ed) 17:2059-69. 2012
    ..Here we highlight recent work that advances our understanding of Src signaling as it relates to E-cadherin associated regulation and EMT in PDAC...
  4. doi request reprint Evolving 'omics' technologies for diagnostics of head and neck cancer
    Nagathihalli S Nagaraj
    Department of Surgery, Division of Surgical Oncology, Vanderbilt University School of Medicine, 21st Ave S, Nashville, TN 37232, USA
    Brief Funct Genomic Proteomic 8:49-59. 2009
    ..This article provides a summary of technologies, potential clinical applications, and challenges of omics in head and neck cancer...
  5. doi request reprint Using genomics to develop novel antibacterial therapeutics
    Nagathihalli S Nagaraj
    Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Crit Rev Microbiol 36:340-8. 2010
    ..This article aims to discuss selected aspects of the bacterial genome, and advocates 'omics'-based techniques to advance the discovery of new therapeutic targets against extracellular bacterial pathogens...
  6. doi request reprint Proteomics: a strategy to understand the novel targets in protein misfolding and cancer therapy
    Nagathihalli S Nagaraj
    Department of Surgery, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Expert Rev Proteomics 7:613-23. 2010
    ..The possibility of targeting the targets to repair or degrade protein misfolding in cancer therapy is discussed...
  7. doi request reprint Diallyl disulfide causes caspase-dependent apoptosis in human cancer cells through a Bax-triggered mitochondrial pathway
    Nagathihalli S Nagaraj
    Division of Surgical Oncology, Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    J Nutr Biochem 21:405-12. 2010
    ..Therefore, the mitochondrial pathway might be the target for cancer chemoprevention and/or chemotherapy by DADS...
  8. pmc Combined blockade of Src kinase and epidermal growth factor receptor with gemcitabine overcomes STAT3-mediated resistance of inhibition of pancreatic tumor growth
    Nagathihalli S Nagaraj
    Department of Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Clin Cancer Res 17:483-93. 2011
    ..The purpose of this study was to translate the current understanding of complementary activated tyrosine kinase signaling pathways by targeting Src kinase and epidermal growth factor receptor (EGFR)...
  9. pmc Targeted inhibition of SRC kinase signaling attenuates pancreatic tumorigenesis
    Nagathihalli S Nagaraj
    Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN, USA
    Mol Cancer Ther 9:2322-32. 2010
    ..These results establish a mechanistic rationale for Src inhibition with dasatinib as a therapeutic target in the treatment of pancreatic cancer and identify potential biomarkers of resistance to Src inhibition...
  10. pmc Targeting the transforming growth factor-beta signaling pathway in human cancer
    Nagathihalli S Nagaraj
    Vanderbilt University School of Medicine, Vanderbilt Ingram Cancer Center, Department of Surgery, Nashville, TN 37232, USA
    Expert Opin Investig Drugs 19:77-91. 2010
    ..This report also examines the therapeutic intervention of TGF-ss signaling in human cancers...