Research Topics
Species | Harvey J MurffSummaryAffiliation: Vanderbilt University Country: USA Publications
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Publications
Dietary intake of PUFAs and colorectal polyp riskHarvey J Murff
Division of General Internal Medicine, Vanderbilt University School of Medicine, Nashville, TN 37203, USA
Am J Clin Nutr 95:703-12. 2012..Marine-derived n-3 (omega-3) PUFAs may reduce risk of developing colorectal cancer; however, few studies have investigated the association of n-3 PUFA intakes on colorectal polyp risk...- Colonoscopy screening in African Americans and Whites with affected first-degree relativesHarvey J Murff
Vanderbilt Epidemiology Center, Nashville, TN 37203 1738, USA
Arch Intern Med 168:625-31. 2008..Racial differences in colon cancer mortality could be related to variations in screening of increased-risk individuals... - A prospective study of dietary polyunsaturated fatty acids and colorectal cancer risk in Chinese womenHarvey J Murff
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
Cancer Epidemiol Biomarkers Prev 18:2283-91. 2009..03). These results suggest that dietary PUFA and the ratio of n-6 to n-3 PUFA intake may be positively associated with colorectal cancer risk, and this association may be mediated in part through PGE(2) production... - Dietary polyunsaturated fatty acids and breast cancer risk in Chinese women: a prospective cohort studyHarvey J Murff
Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203 1738, USA
Int J Cancer 128:1434-41. 2011..The relative amounts of n-6 PUFA to marine-derived n-3 PUFAs may be more important for breast cancer risk than individual dietary amounts of these fatty acids... - Nonsteroidal anti-inflammatory drug use and risk of adenomatous and hyperplastic polypsHarvey J Murff
Division of General Internal Medicine and Public Health, Vanderbilt University Medical Center, Nashville, TN, USA
Cancer Prev Res (Phila) 4:1799-807. 2011..The use of any NSAID regardless of type was associated with a reduced risk of adenomatous polyps; however, regular aspirin and COX-2 inhibitors use was not associated with hyperplastic polyp risk... 
Automated identification of postoperative complications within an electronic medical record using natural language processingHarvey J Murff
Tennessee Valley Healthcare System, Veterans Affairs Medical Center, Nashville, TN, USA
JAMA 306:848-55. 2011..Currently most automated methods to identify patient safety occurrences rely on administrative data codes; however, free-text searches of electronic medical records could represent an additional surveillance approach...- Glycemic and weight changes after persistent use of incident oral diabetes therapy: a Veterans Administration retrospective cohort studyMary Margaret Huizinga
Department of Medicine, Johns Hopkins University, Baltimore, MD, USA
Pharmacoepidemiol Drug Saf 19:1108-12. 2010..Data on comparative effectiveness of OADs in other populations is limited. The objective was to compare the effectiveness of incident OAD regimens in reducing A1C and to compare the effect of OADs on body mass index (BMI)... - Comparative effectiveness of sulfonylurea and metformin monotherapy on cardiovascular events in type 2 diabetes mellitus: a cohort studyChristianne L Roumie
Veterans Affairs Tennessee Valley Healthcare System, 1310 24th Avenue South, Geriatric Research Education Clinical Center, Nashville, TN 37212, USA
Ann Intern Med 157:601-10. 2012..The effects of sulfonylureas and metformin on outcomes of cardiovascular disease (CVD) in type 2 diabetes are not well-characterized... - Reweighted Mahalanobis distance matching for cluster-randomized trials with missing dataRobert A Greevy
VA Tennessee Valley Geriatric Research Education Clinical Center GRECC, Nashville, TN, USA
Pharmacoepidemiol Drug Saf 21:148-54. 2012..The method is illustrated in the context of a cluster-randomized trial. A Web application and an R package are introduced to implement the method and incorporate recent advances in the area... - Comparative effectiveness of incident oral antidiabetic drugs on kidney functionAdriana M Hung
VA Tennessee Valley, Clinical Science Research and Development, Geriatric Research Education Clinical Center GRECC, Department of Medicine, Nashville, TN, USA
Kidney Int 81:698-706. 2012..The risk associated with rosiglitazone was similar to metformin for both outcomes. Thus, compared to metformin, oral antidiabetic drug treatment with sulfonylureas increased the risk of a decline in eGFR, ESRD, or death... - The interaction of age and hormone replacement therapy on colon adenoma riskHarvey J Murff
Division of General Internal Medicine and Public Health, Vanderbilt University Medical Center, Nashville, TN, USA
Cancer Detect Prev 31:161-5. 2007..We re-evaluated this interaction and determined if this interaction may be explained by the longer duration of estrogen use in older, rather than younger, women... - Race and socioeconomic status are independently associated with benign prostatic hyperplasiaJay H Fowke
Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, Tennessee 37203 1738, USA
J Urol 180:2091-6; discussion 2096. 2008..We investigated racial differences in and surgical intervention for benign prostatic hyperplasia in a large and predominantly low income population... - Papanicolaou testing among women in the southern United StatesNeeraja B Peterson
Institute for Medicine and Public Health, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232 8300, USA
J Womens Health (Larchmt) 17:939-46. 2008..We examined Pap testing among southern women, mostly of low income and educational status, to determine if rates were similar to those reported nationally and to examine which factors were related to receipt of Pap tests... 
Colorectal cancer screening among men and women in the United StatesNeeraja B Peterson
Center for Health Services Research, Division of General Medicine and Public Health, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232 8300, USA
J Womens Health (Larchmt) 16:57-65. 2007..A few previous studies have shown that men were more likely than women to be screened for colorectal cancer (CRC)...- Early initiation of colorectal cancer screening in individuals with affected first-degree relativesHarvey J Murff
Division of General Internal Medicine and Public Health, Vanderbilt University Medical Center, Nashville, TN, USA
J Gen Intern Med 22:121-6. 2007..Several guidelines recommend initiating colorectal cancer screening at age 40 for individuals with affected first-degree relatives, yet little evidence exists describing how often these individuals receive screening procedures... - Impact of patient age on family cancer historyHarvey J Murff
Division of General Internal Medicine and Public Health, Vanderbilt University Medical Center, Nashville, Tennessee, USA
Genet Med 8:438-42. 2006..CONCLUSION: For colorectal and breast cancers, younger individuals reporting a family history of these cancers were more likely to report a pedigree with high-risk features than older individuals... - The comprehensiveness of family cancer history assessments in primary careHarvey J Murff
Division of General Internal Medicine, Vanderbilt University Medical Center, Nashville, TN 37212 2637, USA
Community Genet 10:174-80. 2007..Accurate family history information is required for adequate breast and colorectal cancer risk assessments. Few studies have examined the comprehensiveness of the family medical history interview in primary care... - The effect of incident antidiabetic regimens on lipid profiles in veterans with type 2 diabetes: a retrospective cohortChristianne L Roumie
VA Tennessee Valley Geriatric Research Education Clinical Center, HSR and D Targeted Research Enhancement Program for Patient Healthcare Behavior, Clinical Research Center of Excellence, Nashville, TN, USA
Pharmacoepidemiol Drug Saf 20:36-44. 2011..Effects of oral antidiabetic drugs (OADs) on lipids may influence cardiovascular outcomes. Our aim was to compare time to initiation of lipid lowering medication (LLM) and 12-month lipid profiles among new OAD users... - The association of plasma fatty acids with prostate cancer risk in African Americans and AfricansFlora A Ukoli
Dept of Surgery, Meharry Medical College, Nashville, TN 37208, USA
J Health Care Poor Underserved 21:127-47. 2010..These preliminary findings need to be further explored in a larger study that will include risk analysis of fatty-acid ratios to clarify their combined impact on PCa risk... - Detection of blood culture bacterial contamination using natural language processingMichael E Matheny
GRECC and Center for Health Services Research, Veterans Affairs Tennessee Valley Health System, Nashville, TN Division of General Internal Medicine and Public Health, Vanderbilt University MedicalCenter, Nashville, TN Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA
AMIA Annu Symp Proc 2009:411-5. 2009..0% for mapping the antibiotics and bacteria with appropriate sensitivity findings in the test data. The bacterial contamination detection algorithm had a sensitivity of 83.3% and a positive predictive value of 81.8%... - A study of prostaglandin pathway genes and interactions with current nonsteroidal anti-inflammatory drug use in colorectal adenomaTodd L Edwards
Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, TN, USA
Cancer Prev Res (Phila) 5:855-63. 2012..We also observed effect modification of the HPGD signal by NSAID exposure... - Cancer risk assessment: quality and impact of the family history interviewHarvey J Murff
Division of General Internal Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA
Am J Prev Med 27:239-45. 2004..When family history information does identify high-risk individuals, only the minority are referred for genetic services... - Race and family history assessment for breast cancerHarvey J Murff
Division of General Internal Medicine, Vanderbilt University Medical Center, and Department of Veterans Affairs, Nashville, TN 37212 2637, USA
J Gen Intern Med 20:75-80. 2005..The purpose of this study was to determine whether differences exist in the collection of family history information based on patient race... - Detecting adverse events for patient safety research: a review of current methodologiesHarvey J Murff
Department of Veterans Affairs, Tennessee Valley Healthcare System, GRECC, 1310 24th Avenue South, Nashville, TN 37212 2637, USA
J Biomed Inform 36:131-43. 2003..But these systems will perform optimally only if we improve our understanding of the fundamental nature of errors and the ways in which the human mind can naturally, but erroneously, contribute to the problems that we observe... - Understanding of drug indications by ambulatory care patientsStephen D Persell
Division of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611 2927, USA
Am J Health Syst Pharm 61:2523-7. 2004..Patients' knowledge of the indications of their prescription medications was studied and those medications that were most likely to be taken without patients understanding the correct indication were identified... - Who Said It? Establishing Professional Attribution among Authors of Veterans' Electronic Health RecordsRuth M Reeves
Health Services Research and Development, Tennessee Valley Healthcare System, Department of Veterans Affairs, 1310 24 Avenue South, Nashville, TN 37212, USA Department of Biomedical Informatics, Vanderbilt University Medical Center, 2209 Garland Avenue, Nashville, TN 37232, USA
AMIA Annu Symp Proc 2012:753-62. 2012..We evaluated and compared free form electronic signatures against LOINC note titles in categorizing the profession of EHR authors... - Assessment of adverse drug events among patients in a tertiary care medical centerPhilip E Johnston
Department of Pharmaceutical Services, Vanderbilt University Medical Center VUMC, Nashville, TN 37232, USA
Am J Health Syst Pharm 63:2218-27. 2006..Specific patient and clinical characteristics associated with an increased risk of sustaining an adverse event (AE) were identified... - Does this patient have a family history of cancer? An evidence-based analysis of the accuracy of family cancer historyHarvey J Murff
Division of General Internal Medicine, Vanderbilt University Medical Center, and Department of Veterans Affairs, Tennessee Valley Healthcare System, Research Education and Clinical Center, Nashville, Tenn 37212 2637, USA
JAMA 292:1480-9. 2004..A family history of certain cancers is associated with an increased risk of developing cancer. Both cancer screening and genetic services referral decisions are often based on self-reported pedigree information... - Research participant safety and systems factors in general clinical research centersHarvey J Murff
Department of Veterans Affairs, Tennessee Valley Healthcare System, GRECC, Nashville, TN, USA
IRB 28:8-14. 2006 - Patient satisfaction profiling of individual physicians: impact of panel statusHarvey J Murff
Vanderbilt University Medical Center, Division of General Internal Medicine, Nashville, TN, USA
J Eval Clin Pract 10:553-61. 2004..Further research is necessary to determine if panel status might also confound patient satisfaction... - Electronically screening discharge summaries for adverse medical eventsHarvey J Murff
Division of General Internal Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA
J Am Med Inform Assoc 10:339-50. 2003..Nonetheless, computerized clinical narrative screening methods could potentially offer researchers and quality managers a means to routinely detect adverse events... - The effect of incident antidiabetic regimens on lipid profiles in veterans with type 2 diabetes: a retrospective cohortChristianne L Roumie
VA Tennessee Valley Geriatric Research Education Clinical Center GRECC, HSR and D Targeted Research Enhancement Program for Patient Healthcare Behavior, Clinical Research Center of Excellence CRCoE, Nashville, TN, USA
Pharmacoepidemiol Drug Saf 20:36-44. 2011..Effects of oral antidiabetic drugs (OADs) on lipids may influence cardiovascular outcomes. Our aim was to compare time to initiation of lipid lowering medication (LLM) and 12-month lipid profiles among new OAD users... - The impact of family history of diabetes on glucose testing and counseling behavior in primary careHarvey J Murff
Division of General Internal Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA
Diabetes Care 27:2247-8. 2004 - Use of colonoscopy and flexible sigmoidoscopy among African Americans and whites in a low-income populationNeeraja B Peterson
Prev Chronic Dis 5:A28. 2008 - "I wish I had seen this test result earlier!": Dissatisfaction with test result management systems in primary careEric G Poon
Division of General Medicine and Primary Care, Brigham and Women s Hospital, Boston, Mass 02120, USA
Arch Intern Med 164:2223-8. 2004..Therefore, we sought to identify problems in current test result management systems and possible ways to improve these systems... - General clinical research center staff nurse perceptions and behaviors regarding informed consent: results of a national surveyHarvey J Murff
Department of Veterans' Affairs, USA
IRB 28:8-12. 2006
Research Grants
- Mechanisms and Management of Familial Colon CancerHarvey Murff; Fiscal Year: 2007..The experience gained from this career development award will ensure Dr. Murff's transition into an independent researcher in cancer epidemiology. ..
- Long-Chain Fatty Acids, Oxidative Stress and Colorectal Neoplasm RiskHarvey J Murff; Fiscal Year: 2010..The purpose of this study is to determine if omega-3 fatty acids reduce the risk of colorectal adenomas and diminishes the production of inflammatory and oxidative stress biomarkers. ..