Research Topics
Genomes and GenesSpecies | Thomas M MorganSummaryAffiliation: Vanderbilt University Country: USA Publications
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Publications
Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication studyThomas M Morgan
Department of Genetics, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Conn 06510, USA
JAMA 297:1551-61. 2007..Given the numerous, yet inconsistent, reports of genetic variants being associated with acute coronary syndromes (ACS), there is a need for comprehensive validation of ACS susceptibility genotypes...
Investigation of 89 candidate gene variants for effects on all-cause mortality following acute coronary syndromeThomas M Morgan
Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA
BMC Med Genet 9:66. 2008..Many candidate genes have been reported to be risk factors for acute coronary syndrome (ACS), but their impact on clinical prognosis following ACS is unknown...
Primate-specific evolution of noncoding element insertion into PLA2G4C and human preterm birthJevon Plunkett
Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
BMC Med Genomics 3:62. 2010..We hypothesize that higher primate-specific gene evolution may lead to these differences and target genes involved in human preterm birth, an area of global health significance...
Vaccines are not associated with metabolic events in children with urea cycle disordersThomas M Morgan
Department of Pediatrics Division of Genetics and Genomic Medicine, Vanderbilt University School of Medicine, DD 2205 Medical Center North, Nashville, TN 37232 2578, USA
Pediatrics 127:e1147-53. 2011..Patients with UCDs are subject to hyperammonemic episodes (HAEs) after infection, fever, or other stressors...
Investigation of 95 variants identified in a genome-wide study for association with mortality after acute coronary syndromeThomas M Morgan
Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA
BMC Med Genet 12:127. 2011..Genome-wide association studies (GWAS) have identified new candidate genes for the occurrence of acute coronary syndrome (ACS), but possible effects of such genes on survival following ACS have yet to be investigated...
Genetic risk score does not correlate with body mass index of Latina women in a clinical trialKimberly R Coenen
Department of Medicine, Division of Gastroenterology, Vanderbilt University Medical Center, Nashville, Tennessee, USA
Clin Transl Sci 4:323-7. 2011..We conclude that an eight locus GRS has no clinical utility for explaining obesity or predicting response to intervention in Latina women participating in a clinical trial...
Common polymorphisms in human lysyl oxidase genes are not associated with the adolescent idiopathic scoliosis phenotypeTracy L McGregor
Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
BMC Med Genet 12:92. 2011..We hypothesized that common polymorphisms in the five human lysyl oxidase genes (LOX, LOXL1, LOXL2, LOXL3, and LOXL4) may be associated with the phenotype of adolescent idiopathic scoliosis...
Molecular cytogenetic analysis and resequencing of contactin associated protein-like 2 in autism spectrum disordersBetul Bakkaloglu
Program on Neurogenetics, Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA
Am J Hum Genet 82:165-73. 2008....
