Robert Matusik

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. ncbi request reprint Use of tissue recombination to predict phenotypes of transgenic mouse models of prostate carcinoma
    Kenichiro Ishii
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN 37232 2765, USA
    Lab Invest 85:1086-103. 2005
  2. pmc Wnt/β-catenin activation promotes prostate tumor progression in a mouse model
    X Yu
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA
    Oncogene 30:1868-79. 2011
  3. pmc Candidate metastasis suppressor genes uncovered by array comparative genomic hybridization in a mouse allograft model of prostate cancer
    Yajun Yi
    Clinical Research Division, Fred Hutchinson Cancer Research Center and Department of Laboratories, Seattle Children s Hospital, WA, USA
    Mol Cytogenet 2:18. 2009
  4. pmc Human homolog of Drosophila Hairy and enhancer of split 1, Hes1, negatively regulates δ-catenin (CTNND2) expression in cooperation with E2F1 in prostate cancer
    Jian Ping Lu
    Department of Anatomy and Cell Biology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA
    Mol Cancer 9:304. 2010
  5. ncbi request reprint Prostate epithelial cell fate
    Robert J Matusik
    Department of Urologic Surgery, Vanderbilt University Medical Center, A 1302 Medical Center North, 1161 21st Ave South, Nashville, TN 37232 2765, USA
    Differentiation 76:682-98. 2008
  6. pmc Hepsin cooperates with MYC in the progression of adenocarcinoma in a prostate cancer mouse model
    Srinivas Nandana
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2765, USA
    Prostate 70:591-600. 2010
  7. ncbi request reprint The role of forkhead box A2 to restrict androgen-regulated gene expression of lipocalin 5 in the mouse epididymis
    Xiuping Yu
    Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Mol Endocrinol 20:2418-31. 2006
  8. ncbi request reprint Coupled analysis of gene expression and chromosomal location
    Yajun Yi
    Division of Genetic Medicine, Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TX 37232, USA
    Genomics 85:401-12. 2005
  9. pmc Molecular alterations in primary prostate cancer after androgen ablation therapy
    Carolyn J M Best
    Pathogenetics Unit, Laboratory of Pathology, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Clin Cancer Res 11:6823-34. 2005
  10. ncbi request reprint Murine androgen-independent neuroendocrine carcinoma promotes metastasis of human prostate cancer cell line LNCaP
    Kohsuke Uchida
    Department of Urologic Surgery and Andrology, Sapporo Medical University School of Medicine, Sapporo, Japan
    Prostate 66:536-45. 2006

Research Grants

  1. TRANSGENIC MOUSE MODEL FOR PROSTATE CANCER
    Robert Matusik; Fiscal Year: 1999
  2. Control of Prostate Growth and Tumor Progression
    Robert Matusik; Fiscal Year: 2005
  3. Control of Prostate Growth and Tumor Progression
    Robert Matusik; Fiscal Year: 2004
  4. Transgenic Animal Models for Prostate Cancer
    Robert Matusik; Fiscal Year: 2006
  5. CONTROL OF PROSTATE-SPECIFIC GENE EXPRESSION
    Robert Matusik; Fiscal Year: 2006
  6. Control of Prostate Growth and Tumor Progression
    Robert Matusik; Fiscal Year: 2006
  7. Transgenic Animal Models for Prostate Cancer
    Robert Matusik; Fiscal Year: 2007
  8. CONTROL OF PROSTATE-SPECIFIC GENE EXPRESSION
    Robert Matusik; Fiscal Year: 2007
  9. CONTROL OF PROSTATE-SPECIFIC GENE EXPRESSION
    Robert Matusik; Fiscal Year: 2009
  10. Transgenic Animal Models for Prostate Cancer
    Robert Matusik; Fiscal Year: 2009

Collaborators

Detail Information

Publications42

  1. ncbi request reprint Use of tissue recombination to predict phenotypes of transgenic mouse models of prostate carcinoma
    Kenichiro Ishii
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN 37232 2765, USA
    Lab Invest 85:1086-103. 2005
    ..This comparison of tissue recombination to existing models shows that this approach can elicit new information on well-characterized models...
  2. pmc Wnt/β-catenin activation promotes prostate tumor progression in a mouse model
    X Yu
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA
    Oncogene 30:1868-79. 2011
    ..Together, our findings indicate that Wnt/β-catenin signaling has an important role in the progression of mPIN to prostate adenocarcinoma...
  3. pmc Candidate metastasis suppressor genes uncovered by array comparative genomic hybridization in a mouse allograft model of prostate cancer
    Yajun Yi
    Clinical Research Division, Fred Hutchinson Cancer Research Center and Department of Laboratories, Seattle Children s Hospital, WA, USA
    Mol Cytogenet 2:18. 2009
    ..We performed high resolution array comparative genomic hybridization on the metastasizing and non-metastasizing allografts to identify chromosome imbalances that differed between the two groups of tumors...
  4. pmc Human homolog of Drosophila Hairy and enhancer of split 1, Hes1, negatively regulates δ-catenin (CTNND2) expression in cooperation with E2F1 in prostate cancer
    Jian Ping Lu
    Department of Anatomy and Cell Biology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA
    Mol Cancer 9:304. 2010
    ....
  5. ncbi request reprint Prostate epithelial cell fate
    Robert J Matusik
    Department of Urologic Surgery, Vanderbilt University Medical Center, A 1302 Medical Center North, 1161 21st Ave South, Nashville, TN 37232 2765, USA
    Differentiation 76:682-98. 2008
    ....
  6. pmc Hepsin cooperates with MYC in the progression of adenocarcinoma in a prostate cancer mouse model
    Srinivas Nandana
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2765, USA
    Prostate 70:591-600. 2010
    ..However, since the majority of human prostate tumors are adenocarcinomas, the contribution of hepsin in the progression of adenocarcinoma requires further investigation...
  7. ncbi request reprint The role of forkhead box A2 to restrict androgen-regulated gene expression of lipocalin 5 in the mouse epididymis
    Xiuping Yu
    Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Mol Endocrinol 20:2418-31. 2006
    ..We conclude that Foxa2 functions as a repressor that restricts AR regulation of Lcn5 to a segment-specific pattern in the epididymis...
  8. ncbi request reprint Coupled analysis of gene expression and chromosomal location
    Yajun Yi
    Division of Genetic Medicine, Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TX 37232, USA
    Genomics 85:401-12. 2005
    ..We conclude that DIGMAP is a powerful computational tool enabling the coupled analysis of microarray data with genome location...
  9. pmc Molecular alterations in primary prostate cancer after androgen ablation therapy
    Carolyn J M Best
    Pathogenetics Unit, Laboratory of Pathology, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Clin Cancer Res 11:6823-34. 2005
    ..The molecular mechanisms underlying progression are not well known in part due to the rarity of androgen-independent samples from primary and metastatic sites...
  10. ncbi request reprint Murine androgen-independent neuroendocrine carcinoma promotes metastasis of human prostate cancer cell line LNCaP
    Kohsuke Uchida
    Department of Urologic Surgery and Andrology, Sapporo Medical University School of Medicine, Sapporo, Japan
    Prostate 66:536-45. 2006
    ..We investigated the effect of an NE allograft (NE-10) and its cell line, NE-CS, which were established from the prostate of the LPB-Tag 12T-10 transgenic mouse, on human prostate cancer cell line LNCaP...
  11. ncbi request reprint Epididymis-specific promoter-driven gene targeting: a transcription factor which regulates epididymis-specific gene expression
    Kichiya Suzuki
    Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Mol Cell Endocrinol 250:184-9. 2006
    ..2 and 1.3 kb. Our finding provides a framework for further analysis of the epididymal lipocalin gene regulation and modulated control of epididymis-specific expression...
  12. ncbi request reprint Foxa1 and Foxa2 interact with the androgen receptor to regulate prostate and epididymal genes differentially
    Xiuping Yu
    Department of Urologic Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Ann N Y Acad Sci 1061:77-93. 2005
    ..Given that Foxa1 and Foxa2 proteins are expressed differentially in the prostate and epididymis, these data suggest that the Foxa proteins have distinct effects on AR-regulated genes in different male reproductive accessory organs...
  13. ncbi request reprint Molecular evolution of epididymal lipocalin genes localized on mouse chromosome 2
    Kichiya Suzuki
    Department of Urologic Surgery, Vanderbilt University School of Medicine, Room A 1302 MCN, 1161 21st Avenue South, Nashville, TN 37232, USA
    Gene 339:49-59. 2004
    ..The presence and conservation of a cluster of five genes encoding epididymal lipocalins, differently regulated and regionalized in the epididymis, strongly suggests that these proteins may play an important role for male fertility...
  14. ncbi request reprint Androgen-dependent prostate epithelial cell selection by targeting ARR(2)PBneo to the LPB-Tag model of prostate cancer
    Yongqing Wang
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN 37232 2765, USA
    Lab Invest 86:1074-88. 2006
    ..NeoTag cells grafted without rUGM developed undifferentiated adenocarcinoma demonstrating that prostatic stroma dictates the glandular architecture seen in the well-differentiated adenocarcinoma...
  15. pmc Directed differentiation of embryonic stem cells into bladder tissue
    Siam Oottamasathien
    Department of Urologic Surgery, Vanderbilt University Medical Center, and Division of Pediatric Urology, Vanderbilt Children s Hospital Nashville, TN 37232 2765, USA
    Dev Biol 304:556-66. 2007
    ..These approaches allow us to capture specific stages of stem cell differentiation and to better define stem cell hierarchies...
  16. ncbi request reprint Epididymis-specific lipocalin promoters
    Kichiya Suzuki
    Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, 1 1 Seiryo machi, Aoba ku, Sendai 980 8574, Japan
    Asian J Androl 9:515-21. 2007
    ..Our approach provides a basic strategy for further analysis of the epididymal lipocalin gene regulation and flexible control of epididymal function...
  17. ncbi request reprint Neuroendocrine differentiation in the 12T-10 transgenic prostate mouse model mimics endocrine differentiation of pancreatic beta cells
    Aparna Gupta
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2765, USA
    Prostate 68:50-60. 2008
    ....
  18. pmc Stromal transforming growth factor-beta signaling mediates prostatic response to androgen ablation by paracrine Wnt activity
    VERONICA R PLACENCIO
    Departments of Cancer Biology, Urologic Surgery, and Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee, USA
    Cancer Res 68:4709-18. 2008
    ..These studies reveal a novel TGF-beta, androgen, and Wnt paracrine signaling axis that enables prostatic regression of the distal ducts after androgen ablation while supporting proximal duct survival...
  19. doi request reprint Directed differentiation of bone marrow derived mesenchymal stem cells into bladder urothelium
    Govindaraj Anumanthan
    Department of Urologic Surgery, Vanderbilt University Medical Center and Division of Pediatric Urology, Vanderbilt Children s Hospital, Nashville, Tennessee, USA
    J Urol 180:1778-83. 2008
    ..We determined whether nonembryonic stem cells, specifically bone marrow derived mesenchymal stem cells, could serve as a source of pluripotent or multipotent progenitor cells...
  20. doi request reprint Temporal-spatial protein expression in bladder tissue derived from embryonic stem cells
    John C Thomas
    Department of Urologic Surgery, Vanderbilt University Medical Center, Division of Pediatric Urology, Monroe Carell Jr Vanderbilt Children s Hospital, Nashville, Tennessee 37232, USA
    J Urol 180:1784-9. 2008
    ..Differential and temporal expressions of the endodermal proteins known as forkhead box (Foxa1 and Foxa2) were observed. In the current study we further delineated these protein expression patterns...
  21. ncbi request reprint Expression and role of Foxa proteins in prostate cancer
    Janni Mirosevich
    Vanderbilt Prostate Cancer Center, AA 1302 Medical Center North, Nashville, Tennessee 37232 2765, USA
    Prostate 66:1013-28. 2006
    ..In particular, Foxa2 may be involved in progression of prostate cancer to androgen independence. As such, Foxa proteins may represent novel targets for therapeutic intervention...
  22. ncbi request reprint Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation
    Nan Gao
    Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232, USA
    Development 132:3431-43. 2005
    ..These data indicate that Foxa1 plays a pivotal role in controlling prostate morphogenesis and cell differentiation...
  23. ncbi request reprint Epididymal lipocalin-type prostaglandin D2 synthase: identification using mass spectrometry, messenger RNA localization, and immunodetection in mouse, rat, hamster, and monkey
    Sophie Fouchécourt
    Department of Obstetrics and Gynecology, Biochemistry, Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Biol Reprod 66:524-33. 2002
    ....
  24. ncbi request reprint Fibroblast growth factor 8 isoform B overexpression in prostate epithelium: a new mouse model for prostatic intraepithelial neoplasia
    Zhigang Song
    Department of Pathology, University of Southern California, Keck School of Medicine, Los Angeles, California 90033, USA
    Cancer Res 62:5096-105. 2002
    ..These transgenic mice represent a "natural" animal model for investigating the mechanism of development and progression of prostatic diseases, such as prostatic hyperplasia and preneoplastic lesions...
  25. ncbi request reprint Immortalized epididymal cell lines from transgenic mice overexpressing temperature-sensitive simian virus 40 large T-antigen gene
    Yoshihiko Araki
    Center for Reproductive Biology Research, The Department of Obstetrics and Gynecology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Androl 23:854-69. 2002
    ....
  26. ncbi request reprint The 5'-flanking region of the murine epididymal protein of 17 kilodaltons gene targets transgene expression in the epididymis
    Kichiya Suzuki
    Center for Reproductive Biology Research and Department of Obstetrics and Gynecology, Vanderbilt University, School of Medicine, Nashville, Tennessee 37232 2633, USA
    Endocrinology 144:877-86. 2003
    ..The 5.3mEP17 fragment will be useful to express a foreign gene of interest in the epididymis in an initial segment-specific manner...
  27. ncbi request reprint Identification, immunolocalization, regulation, and postnatal development of the lipocalin EP17 (epididymal protein of 17 kilodaltons) in the mouse and rat epididymis
    Sophie Fouchécourt
    Department of Obstetrics and Gynecology and Center for Reproductive Biology Research, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Endocrinology 144:887-900. 2003
    ..This suggests that these two related proteins exhibit distinct functions in the mouse epididymis...
  28. ncbi request reprint Elevated expression of 12/15-lipoxygenase and cyclooxygenase-2 in a transgenic mouse model of prostate carcinoma
    Scott B Shappell
    Department of Pathology, Vanderbilt Prostate Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2561, USA
    Cancer Res 63:2256-67. 2003
    ....
  29. ncbi request reprint The role of hepatocyte nuclear factor-3 alpha (Forkhead Box A1) and androgen receptor in transcriptional regulation of prostatic genes
    Nan Gao
    Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Mol Endocrinol 17:1484-507. 2003
    ..Taken together, these data support a model in which regulatory cues from the cell lineage and the extracellular environment coordinately establish the prostatic differentiated response...
  30. pmc The loss of TGF-beta signaling promotes prostate cancer metastasis
    William H Tu
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Neoplasia 5:267-77. 2003
    ..Our study demonstrates for the first time that a disruption of TGF-beta signaling in prostate cancer plays a causal role in promoting tumor metastasis...
  31. ncbi request reprint Prostate-specific antitumor activity by probasin promoter-directed p202 expression
    Yong Wen
    Department of Molecular and Cellular Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Mol Carcinog 37:130-7. 2003
    ..Together, our results suggest that p202 suppresses prostate tumor growth, and that a prostate-specific antitumor effect can be achieved by systemic administration of liposome-mediated delivery of ARR2PB-p202...
  32. ncbi request reprint An androgen-dependent upstream enhancer is essential for high levels of probasin gene expression
    Jianfeng Zhang
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2765, USA
    Endocrinology 145:134-48. 2004
    ..The PB promoter creates a model that contains six AR binding sites that function in a cooperative manner for maximum androgen-regulated prostate-specific gene transcription...
  33. ncbi request reprint An allograft model of androgen independent prostatic neuroendocrine carcinoma derived from a large probasin promoter-T antigen transgenic mouse line
    Naoya Masumori
    Department of Urologic Survey, Vanderbilt Prostate Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    J Urol 171:439-42. 2004
    ..Animal models that mimic this hormone refractory prostate cancer may be useful for developing and testing novel treatment strategies...
  34. ncbi request reprint Expression of Foxa transcription factors in the developing and adult murine prostate
    Janni Mirosevich
    Vanderbilt Prostate Cancer Center, Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232 2765, USA
    Prostate 62:339-52. 2005
    ..Currently, the developmental expression pattern of Foxa proteins in the murine prostate is unknown...
  35. ncbi request reprint Epididymis-specific promoter-driven gene targeting: a new approach to control epididymal function?
    Kichiya Suzuki
    Department of Obstetric and Gynecology, Vanderbilt Univerity School of Medicine, Nashville, TN 37232, USA
    Mol Cell Endocrinol 216:15-22. 2004
  36. ncbi request reprint Hepsin promotes prostate cancer progression and metastasis
    Olga Klezovitch
    Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Cancer Cell 6:185-95. 2004
    ..We provide in vivo evidence that upregulation of a cell surface serine protease in a primary tumor promotes cancer progression and metastasis...
  37. ncbi request reprint NE-10 neuroendocrine cancer promotes the LNCaP xenograft growth in castrated mice
    Ren Jie Jin
    Department of Urologic Surgery, Vanderbilt University Medical Center, A 1302 Medical Center North, Nashville, TN 37232 2765, USA
    Cancer Res 64:5489-95. 2004
    ....
  38. pmc Tissue-specific transcriptional targeting of a replication-competent retroviral vector
    Christopher R Logg
    Institute for Genetic Medicine, Keck School of Medicine, University of Southern California, 2250 Alcazar Street, Los Angeles, CA 90033, USA
    J Virol 76:12783-91. 2002
    ..Our results have thus identified promoter strength and positioning within the LTR as important determinants for achieving both high transduction efficiency and strict cell type specificity in transcriptionally targeted RCR vectors...
  39. ncbi request reprint Immortalization by large T-antigen of the adult epididymal duct epithelium
    Christiane Kirchhoff
    Division of Reproductive Sciences, IHF Institute for Hormone and Fertility Research, University of Hamburg, Germany
    Mol Cell Endocrinol 216:83-94. 2004
    ..In the second in vivo approach a tissue-specific promoter, the 5kb GPX5 promoter, was used to direct expression of the large T-antigen to the epididymal duct epithelium...
  40. pmc The nuclear factor-kappaB pathway controls the progression of prostate cancer to androgen-independent growth
    Ren Jie Jin
    Vanderbilt Prostate Cancer Center and Department of Urologic Surgery, Vanderbilt University Medical Center, A1329 MCN, 1161 21st Avenue South, Nashville, TN 37232 2765, USA
    Cancer Res 68:6762-9. 2008
    ..Thus, the NF-kappaB pathway may be a potential target for therapy against androgen-independent prostate cancer...
  41. doi request reprint Down-regulation of p57Kip2 induces prostate cancer in the mouse
    Ren Jie Jin
    Vanderbilt Prostate Cancer Center and Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tenessee, USA
    Cancer Res 68:3601-8. 2008
    ..Therefore, these results strongly suggest that p57(Kip2) is an important gene in prostate cancer tumorigenesis, and the p57(Kip2) pathway may be a potential target for prostate cancer prevention and therapy...
  42. pmc Role of nicotinic and estrogen signaling during experimental acute and chronic bladder inflammation
    Magaly Martinez-Ferrer
    Department of Urologic Surgery, Vanderbilt Ingram Cancer Center, Vanderbilt University, A 1302 Medical Center North, 1161 21st Ave South, Nashville, TN 37232, USA
    Am J Pathol 172:59-67. 2008
    ..These data suggest that 17 beta-estradiol and anabasine reduce chronic bladder inflammation through reduction of nuclear translocation of p65 to suppress cytokine expression...

Research Grants27

  1. TRANSGENIC MOUSE MODEL FOR PROSTATE CANCER
    Robert Matusik; Fiscal Year: 1999
    ..These new transgenic CaP models will facilitate the elucidation of molecular events from the early stages of prostatic carcinogenesis to the late stages of tumor progression. ..
  2. Control of Prostate Growth and Tumor Progression
    Robert Matusik; Fiscal Year: 2005
    ..abstract_text> ..
  3. Control of Prostate Growth and Tumor Progression
    Robert Matusik; Fiscal Year: 2004
    ..abstract_text> ..
  4. Transgenic Animal Models for Prostate Cancer
    Robert Matusik; Fiscal Year: 2006
    ....
  5. CONTROL OF PROSTATE-SPECIFIC GENE EXPRESSION
    Robert Matusik; Fiscal Year: 2006
    ..abstract_text> ..
  6. Control of Prostate Growth and Tumor Progression
    Robert Matusik; Fiscal Year: 2006
    ..abstract_text> ..
  7. Transgenic Animal Models for Prostate Cancer
    Robert Matusik; Fiscal Year: 2007
    ....
  8. CONTROL OF PROSTATE-SPECIFIC GENE EXPRESSION
    Robert Matusik; Fiscal Year: 2007
    ..abstract_text> ..
  9. CONTROL OF PROSTATE-SPECIFIC GENE EXPRESSION
    Robert Matusik; Fiscal Year: 2009
    ....
  10. Transgenic Animal Models for Prostate Cancer
    Robert Matusik; Fiscal Year: 2009
    ..Results from our animal studies will have a high-impact of explaining failure to androgen-ablation therapy and in defining new routes of therapeutic intervention. ..
  11. CONTROL OF PROSTATE-SPECIFIC GENE EXPRESSION
    Robert J Matusik; Fiscal Year: 2010
    ....
  12. CONTROL OF PROSTATE-SPECIFIC GENE EXPRESSION
    Robert Matusik; Fiscal Year: 2009
    ....
  13. CONTROL OF PROSTATE-SPECIFIC GENE EXPRESSION
    Robert Matusik; Fiscal Year: 2005
    ..abstract_text> ..
  14. Transgenic Animal Models for Prostate Cancer
    Robert Matusik; Fiscal Year: 2005
    ....
  15. Control of Prostate Growth and Tumor Progression
    Robert Matusik; Fiscal Year: 2004
    ..abstract_text> ..
  16. TRANSGENIC MOUSE MODEL FOR PROSTATE CANCER
    Robert Matusik; Fiscal Year: 2000
    ..These new transgenic CaP models will facilitate the elucidation of molecular events from the early stages of prostatic carcinogenesis to the late stages of tumor progression. ..
  17. CONTROL OF PROSTATE-SPECIFIC GENE EXPRESSION
    Robert Matusik; Fiscal Year: 2000
    ..The ultimate goal is to provide a basic understanding of prostatic epithelial cell gene expression that will lead to insight in male infertility and the mechanism that lead to prostatic disease. ..
  18. TRANSGENIC MOUSE MODEL FOR PROSTATE CANCER
    Robert Matusik; Fiscal Year: 2001
    ..These new transgenic CaP models will facilitate the elucidation of molecular events from the early stages of prostatic carcinogenesis to the late stages of tumor progression. ..
  19. CONTROL OF PROSTATE-SPECIFIC GENE EXPRESSION
    Robert Matusik; Fiscal Year: 2001
    ..The ultimate goal is to provide a basic understanding of prostatic epithelial cell gene expression that will lead to insight in male infertility and the mechanism that lead to prostatic disease. ..
  20. TRANSGENIC MOUSE MODEL FOR PROSTATE CANCER
    Robert Matusik; Fiscal Year: 2002
    ..These new transgenic CaP models will facilitate the elucidation of molecular events from the early stages of prostatic carcinogenesis to the late stages of tumor progression. ..
  21. CONTROL OF PROSTATE-SPECIFIC GENE EXPRESSION
    Robert Matusik; Fiscal Year: 2002
    ..The ultimate goal is to provide a basic understanding of prostatic epithelial cell gene expression that will lead to insight in male infertility and the mechanism that lead to prostatic disease. ..
  22. CONTROL OF PROSTATE-SPECIFIC GENE EXPRESSION
    Robert Matusik; Fiscal Year: 2003
    ..abstract_text> ..
  23. Transgenic Animal Models for Prostate Cancer
    Robert Matusik; Fiscal Year: 2003
    ....
  24. Control of Prostate Growth and Tumor Progression
    Robert Matusik; Fiscal Year: 2003
    ..abstract_text> ..
  25. CONTROL OF PROSTATE-SPECIFIC GENE EXPRESSION
    Robert Matusik; Fiscal Year: 2004
    ..abstract_text> ..
  26. Transgenic Animal Models for Prostate Cancer
    Robert Matusik; Fiscal Year: 2004
    ....
  27. Transgenic Animal Models for Prostate Cancer
    Robert J Matusik; Fiscal Year: 2010
    ..Results from our animal studies will have a high-impact of explaining failure to androgen-ablation therapy and in defining new routes of therapeutic intervention. ..