Research Topics
Genomes and GenesSpecies | Charles E MatthewsSummaryAffiliation: Vanderbilt University Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Physical activity and risk of endometrial cancer: a report from the Shanghai endometrial cancer studyCharles E Matthews
Division of General Internal Medicine, Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Medical Center East, Suite 6100, Nashville, TN 37232 8300, USA
Cancer Epidemiol Biomarkers Prev 14:779-85. 2005..These findings suggest that both lifestyle activities of lower intensity (e.g., walking and doing household chores) and intentional exercise can reduce endometrial cancer risk...
Development and testing of a short physical activity recall questionnaireCharles E Matthews
Division of General Internal Medicine, Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
Med Sci Sports Exerc 37:986-94. 2005..To develop and test two different short telephone activity recall (STAR) questionnaires, one with closed-ended and the other with open-ended response options, that assessed overall moderate and vigorous activity in a usual week...
Amount of time spent in sedentary behaviors in the United States, 2003-2004Charles E Matthews
Institute for Medicine and Public Health, Department of Medicine, School of Medicine, Vanderbilt University, Nashville, TN 37232 1738, USA
Am J Epidemiol 167:875-81. 2008..These data provide the first objective measure of the amount of time spent in sedentary behavior in the US population and indicate that Americans spend the majority of their time in behaviors that expend very little energy...
Physical activity, body size, and estrogen metabolism in womenCharles E Matthews
Vanderbilt Ingram Cancer Center, Center for Health Services Research, Vanderbilt University Medical Center, Medical Center East, Suite 6100, Nashville, TN 37232 8300, USA
Cancer Causes Control 15:473-81. 2004..We examined these relationships in cross-sectional analyses of 157 North American and Chinese women...
Calibration of accelerometer output for adultsCharles E Matthew
Department of Medicine, Division of General Internal Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA
Med Sci Sports Exerc 37:S512-22. 2005....
Evaluation of a 12-week home-based walking intervention for breast cancer survivorsCharles E Matthews
Department of Medicine, Division of General Internal Medicine and Public Health, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232 8300, USA
Support Care Cancer 15:203-11. 2007..To evaluate a 12-week home-based walking intervention among breast cancer survivors and to quantify changes in physical activity (PA) behaviors, body weight, and body composition in response to the intervention...
Influence of exercise, walking, cycling, and overall nonexercise physical activity on mortality in Chinese womenCharles E Matthews
Department of Medicine, Division of General Internal Medicine and Public Health, Vanderbilt Epidemiology Center, Vanderbilt University Medical School, Nashville, TN 37203 1738, USA
Am J Epidemiol 165:1343-50. 2007..62, 0.99). These findings add new evidence that overall physical activity levels are an important determinant of longevity, and that health benefit can be obtained through an active lifestyle, exercise, or combinations of both...
Patterns and correlates of physical activity: a cross-sectional study in urban Chinese womenAdriana L Jurj
Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37203, USA
BMC Public Health 7:213. 2007..The purpose of this study was to investigate the patterns and correlates of physical activity in middle-aged and elderly women from urban Shanghai...
Energy balance, insulin resistance biomarkers, and breast cancer riskAlecia Malin Fair
Meharry Medical College, School of Medicine, Department of Surgery, 1005 Dr D B Todd Jr Boulevard, Nashville, TN 37208 3599, USA
Cancer Detect Prev 31:214-9. 2007....
Racial differences in the association between body mass index and serum IGF1, IGF2, and IGFBP3Jay H Fowke
Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, 2525 West End Avenue, Nashville, Tennessee 37203 1738, USA
Endocr Relat Cancer 17:51-60. 2010..The effects of obesity throughout life on the IGF axis and racial differences in breast cancer risk require study...
HTR1B, ADIPOR1, PPARGC1A, and CYP19A1 and obesity in a cohort of Caucasians and African Americans: an evaluation of gene-environment interactions and candidate genesTodd L Edwards
Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37203, USA
Am J Epidemiol 175:11-21. 2012..A SNP in CYP19A1 interacted with dietary energy intake in African Americans, and another SNP in CYP191A had an independent association with BMI in Caucasians...
Energy balance and breast cancer riskAlecia Malin
Department of Surgery, Meharry Medical College, 1005 Dr D B Todd Boulevard, Nashville, Tennessee 37208, USA
Cancer Epidemiol Biomarkers Prev 14:1496-501. 2005..74; 95% confidence interval, 2.05-12.20). Our study suggests that promotion of behavior patterns that optimize energy balance (weight control and increasing physical activity) may be a viable option for breast cancer prevention...
Evaluation of a questionnaire to assess sedentary and active behaviors in the Southern Community Cohort StudyMaciej S Buchowski
Department of Medicine, Vanderbilt University, Nashville, TN, USA
J Phys Act Health 9:765-75. 2012..This study evaluated the PA questionnaire (PAQ) used in the Southern Cohort Community Study, a prospective investigation of health disparities between African-American and white adults...
Physical activity and obesity gap between black and white women in the southeastern U.SMaciej S Buchowski
Department of Medicine, Vanderbilt University, Nashville, Tennessee 37232, USA
Am J Prev Med 39:140-7. 2010..Differences between black and white women in the associations of sedentary and active behaviors and obesity are mostly unknown...
Reproducibility and validity of the Shanghai Women's Health Study physical activity questionnaireCharles E Matthews
Department of Medicine, Vanderbilt Ingram Cancer Center, Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN 37232 8300, USA
Am J Epidemiol 158:1114-22. 2003..88). These data indicate that the SWHS PAQ is a reproducible and valid measure of exercise behaviors and that it demonstrates utility in stratifying women by levels of important lifestyle activities (e.g., housework, walking, cycling)...
Physical activity and the incidence of type 2 diabetes in the Shanghai women's health studyRaquel Villegas
Department of Medicine, Vanderbilt Epidemiology Center Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
Int J Epidemiol 35:1553-62. 2006....
Relationship between smoking and obesity among womenKushal Patel
Prevention Research Unit, Department of Internal Medicine, School of Medicine, Meharry Medical College, Nashville, TN, USA
Am J Health Behav 35:627-36. 2011..To examine the relationship between smoking and weight status in adult women and whether this association differed by race...
Reproducibility and validity of the Shanghai Men's Health Study physical activity questionnaireAdriana L Jurj
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN 37232 8300, USA
Am J Epidemiol 165:1124-33. 2007..62-0.77). Results indicate that the Shanghai Men's Health Study PAQ has reasonable reproducibility and validity for classifying men by their level of exercise and nonexercise activities in this cohort...
Joint effects of body size, energy intake, and physical activity on breast cancer riskAesun Shin
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA
Breast Cancer Res Treat 113:153-61. 2009..76) and high total physical activity (>20.5 MET-h/day). We did not find a statistically significant multiplicative interaction between body size, caloric intake and total physical activity on breast cancer risk...
Evaluation of a questionnaire to assess sedentary and active behaviors in the southern community cohort studyMaciej S Buchowski
Dept of Medicine, Vanderbilt University, Nashville, TN
J Phys Act Health 9:765-75. 2012..This study evaluated the PA questionnaire (PAQ) used in the Southern Cohort Community Study, a prospective investigation of health disparities between African-American and white adults...
Exercise after diagnosis of breast cancer in association with survivalXiaoli Chen
Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA
Cancer Prev Res (Phila) 4:1409-18. 2011..An interaction between disease stage and hormone receptor status and total mortality was noted. Our study suggests that exercise after breast cancer diagnosis may improve overall and disease-free survival...
PSA and body composition by dual X-ray absorptiometry (DXA) in NHANESJay H Fowke
Division of Epidemiology, Vanderbilt University Medical Center, Nashville, Tennessee 37203, USA
Prostate 70:120-5. 2010..Several studies also report that obese men have lower blood PSA levels, suggesting that obesity may be interfering with the ability to detect early-stage prostate cancer...
Anterior cruciate ligament reconstruction autograft choice: bone-tendon-bone versus hamstring: does it really matter? A systematic reviewKurt P Spindler
Vanderbilt University Medical Center, Nashville, Tennessee, USA
Am J Sports Med 32:1986-95. 2004..With numbers available, failure rates were not significantly different between groups. These findings suggest that graft type may not be the primary determinant for successful outcomes after anterior cruciate ligament surgery...
Validation of accelerometer wear and nonwear time classification algorithmLeena Choi
Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN 37232 2260, USA
Med Sci Sports Exerc 43:357-64. 2011..A vital step in PA measurement is the classification of daily time into accelerometer wear and nonwear intervals using its recordings (counts) and an accelerometer-specific algorithm...
A small number of candidate gene SNPs reveal continental ancestry in African AmericansNuri Kodaman
Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA
Ann Hum Genet 77:56-66. 2013..Our results demonstrate that a small number of SNPs randomly selected from candidate genes can be used to estimate admixture proportions in African Americans reliably...
Effects of obesity and height on prostate-specific antigen (PSA) and percentage of free PSA levels among African-American and Caucasian menJay H Fowke
Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
Cancer 107:2361-7. 2006..The association between body mass index (BMI) and height on PSA and percentage of free PSA (%fPSA) was investigated within AA and CA men without a prior prostate cancer diagnosis...
Gender differences in predictors of body weight and body weight change in healthy adultsDavid E Chiriboga
Division of Preventive and Behavioral Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
Obesity (Silver Spring) 16:137-45. 2008..Analysis of naturally occurring changes in body weight can provide valuable insights in improving our understanding of the influence of demographic, lifestyle, and psychosocial factors on weight gain in middle-age adults...
Reading and reviewing the orthopaedic literature: a systematic, evidence-based medicine approachKurt P Spindler
Department of Orthopaedics and Rehabilitation, Vanderbilt University Medical School, Nashville, TN 37232-8774, USA
J Am Acad Orthop Surg 13:220-9. 2005..Sufficiently valid evidence-based information ultimately will help in making decisions regarding patient care...
Physical activity and reduced risk of incident sporadic colorectal adenomas: observational support for mechanisms involving energy balance and inflammation modulationKeith G Hauret
Directorate of Epidemiology and Disease Surveillance, US Army Center for Health Promotion and Preventive Medicine, Aberdeen Proving Ground, MD, USA
Am J Epidemiol 159:983-92. 2004..Furthermore, the results suggest indirectly that biologic mechanisms related to inflammation may play a role in the beneficial effect of physical activity on the risk of incident adenoma...
Effect of adiposity and fat distribution on endometrial cancer risk in Shanghai womenWang Hong Xu
Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China
Am J Epidemiol 161:939-47. 2005..05). Upper-body obesity was related to increased risk among women with low BMI. These results suggest that obesity, particularly upper-body fat deposition, is associated with an increased risk of endometrial cancer...
Body mass index, but not physical activity, is associated with C-reactive proteinEric S Rawson
Divisions of Preventive and Behavioral Medicine and Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
Med Sci Sports Exerc 35:1160-6. 2003....
Urban, rural, and regional variations in physical activitySarah Levin Martin
Centers for Disease Control and Prevention, Division of Nutrition and Physical Activity, Physical Activity and Health Branch, Atlanta, GA 30341, USA
J Rural Health 21:239-44. 2005..S. citizens met the recommended levels of PA across the United States. In addition, the association between PIA/PA and degree of urbanization in the 4 main U.S. regions (Northeast, Midwest, South, and West) was determined...
Comparison of pedometer and accelerometer measures of free-living physical activityCatrine Tudor-Locke
Department of Exercise and Wellness, Arizona State University East, 7001 E Williams Field Road, Mesa, AZ 85212, USA
Med Sci Sports Exerc 34:2045-51. 2002....
Sources of variance in daily physical activity levels as measured by an accelerometerCharles E Matthews
Department of Epidemiology and Biostatistics, Norman J Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA
Med Sci Sports Exerc 34:1376-81. 2002..To examine sources of variance in objective measures of physical activity in a group of healthy adults (N = 92) participating in a physical activity measurement study...
Association of physical activity with hormone receptor status: the Shanghai Breast Cancer StudySwann Arp Adams
The Cancer Prevention and Control Program and Department of Epidemiology and Biostatistics, University of South Carolina, Room 241, 2221 Devine Street, Columbia, SC 29208, USA
Cancer Epidemiol Biomarkers Prev 15:1170-8. 2006..58 and 0.28, respectively). These findings suggest that physical activity may reduce breast cancer risk through both hormonal and nonhormonal pathways...
The effect of social desirability and social approval on self-reports of physical activitySwann Arp Adams
Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC 29203, USA
Am J Epidemiol 161:389-98. 2005..30, 0.005). Body size was not associated with reporting bias in this study. The authors conclude that social desirability and social approval may influence self-reported physical activity on some survey instruments...
Systematic errors in middle-aged women's estimates of energy intake: comparing three self-report measures to total energy expenditure from doubly labeled waterJames R Hebert
Department of Epidemiology and Biostatistics and the Nutrition Research Center, University of South Carolina, Columbia, SC 29208, USA
Ann Epidemiol 12:577-86. 2002....
Accelerometer data reduction: a comparison of four reduction algorithms on select outcome variablesLouise C Masse
Health Promotion Research Branch, Behavioral Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20895 7335, USA
Med Sci Sports Exerc 37:S544-54. 2005..This paper a) reviews decision rules researchers have used in the past, b) compares the impact of using different decision rules on a common data set, and c) identifies issues to consider for accelerometer data reduction...
Moderate to vigorous physical activity and risk of upper-respiratory tract infectionCharles E Matthews
Department of Epidemiology and Biostatistics, Norman J Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA
Med Sci Sports Exerc 34:1242-8. 2002..This investigation examined differences in URTI risk between physically inactive and moderately active adults...
Reliability and validity of YRBS physical activity items among middle school studentsPhilip J Troped
Department of Health and Kinesiology, Purdue University, West Lafayette, IN 47907 2046, USA
Med Sci Sports Exerc 39:416-25. 2007..To assess test-retest reliability and validity of the Youth Risk Behavior Survey (YRBS) items for moderate and vigorous physical activity in middle school students...
Physical activity in the United States measured by accelerometer: commentCharles E Matthews
Med Sci Sports Exerc 40:1188; author reply 1189. 2008
Prediction of activity mode with global positioning system and accelerometer dataPhilip J Troped
Department of Health and Kinesiology, Purdue University, West Lafayette, IN 47907 2046, USA
Med Sci Sports Exerc 40:972-8. 2008..The primary aim of this pilot study was to assess how well the combination of global positioning system (GPS) and accelerometer data predicted different activity modes...
Reliability and validity of the Past Year Total Physical Activity QuestionnaireChristine M Friedenreich
Division of Population Health and Information, Alberta Cancer Board, Calgary, Alberta, Canada
Am J Epidemiol 163:959-70. 2006..37 and 0.32 at baseline and follow-up, respectively. In general, the PYTPAQ has acceptable reliability and validity for measurement of past-year physical activity that is comparable to that of similar questionnaires...
The role of measurement error in estimating levels of physical activityPietro Ferrari
Nutrition and Hormones Group, International Agency for Research on Cancer, Lyon, France
Am J Epidemiol 166:832-40. 2007....
Interventions to increase walking behaviorDavid M Williams
Brown Medical School and The Miriam Hospital, Centers for Behavioral and Preventive Medicine, Providence, RI 02903, USA
Med Sci Sports Exerc 40:S567-73. 2008..Incorporating individually tailored programs into broader mass media campaigns may be an important next step, and the Internet could be a useful vehicle...
Research Grants
- PHYSICAL ACTIVITY, ENERGY BALANCE, AND COLON CANCER RISKCharles Matthews; Fiscal Year: 2002..This work will extend our understanding of the biological mechanisms underlying these causal relationships. ..
- Energy Homeostasis and Cancer: Biomarkers and LifestylesCharles Matthews; Fiscal Year: 2007..This work will also serve as the basis for submission of competitive R01 proposals by the candidate in latter years of this award. ..
- Investigation of Measurement Error Correction Models for Physical ActivityCharles Matthews; Fiscal Year: 2007..Collectively, this research will extend our understanding of the influence of measurement errors in PA studies and indicate the next steps necessary to minimize these errors in future studies. ..
