Research Topics
| Michael E MathenySummaryAffiliation: Vanderbilt University Country: USA Publications
| Collaborators
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Detail Information
Publications
Hypoglycemia and clinical outcomes in patients with diabetes hospitalized in the general wardAlexander Turchin
Brigham and Women s Hospital, Boston, Massachusetts, USA
Diabetes Care 32:1153-7. 2009..In this study, we aimed to determine whether hypoglycemic episodes are associated with higher mortality in diabetic patients hospitalized in the general ward...- Evaluation of an automated safety surveillance system using risk adjusted sequential probability ratio testingMichael E Matheny
GRECC and Center for Health Services Research, Tennessee Valley Healthcare System, Veterans Administration, Nashville, TN, USA
BMC Med Inform Decis Mak 11:75. 2011..We compared risk-adjusted sequential probability ratio testing (RA-SPRT) implemented in an automated tool to Massachusetts public reports of 30-day mortality after isolated coronary artery bypass graft surgery... - Validation of an automated safety surveillance system with prospective, randomized trial dataMichael E Matheny
Department of Radiology, Division of General Medicine, Brigham and Women s Hospital, Boston, MA, USA
Med Decis Making 29:247-56. 2009..We sought to validate 3 methods for automated safety monitoring by evaluating clinical trials with elevated adverse events... 
Risk-adjusted sequential probability ratio test control chart methods for monitoring operator and institutional mortality rates in interventional cardiologyMichael E Matheny
Decision Systems Group, Department of Radiology, Brigham and Women s Hospital, MA, USA
Am Heart J 155:114-20. 2008....- Treatment intensification and blood glucose control among hospitalized diabetic patientsMichael E Matheny
Decision Systems Group, Brigham and Women s Hospital, Boston, MA 02115, USA
J Gen Intern Med 23:184-9. 2008..We evaluated the relationship between treatment intensification and changes in blood glucose in hospitalized diabetic patients... 
Development of inpatient risk stratification models of acute kidney injury for use in electronic health recordsMichael E Matheny
Geriatric Research Education Clinical Center, Tennessee Valley Health System, Veterans Health Administration, Nashville, TN, USA
Med Decis Making 30:639-50. 2010....- Occurrence of adverse, often preventable, events in community hospitals involving nephrotoxic drugs or those excreted by the kidneyBalthasar L Hug
Division of General Internal Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02120 1613, USA
Kidney Int 76:1192-8. 2009..Our study shows that ADEs were common in patients with impaired kidney function in community hospitals, and many appear potentially preventable with renal dose checking... - Estimating baseline kidney function in hospitalized patients with impaired kidney functionEdward D Siew
Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
Clin J Am Soc Nephrol 7:712-9. 2012..No consensus exists on how to optimally determine baseline kidney function when multiple preadmission creatinine measurements are available... - Automated identification of postoperative complications within an electronic medical record using natural language processingHarvey J Murff
Tennessee Valley Healthcare System, Veterans Affairs Medical Center, Nashville, TN, USA
JAMA 306:848-55. 2011..Currently most automated methods to identify patient safety occurrences rely on administrative data codes; however, free-text searches of electronic medical records could represent an additional surveillance approach... - Quantitative impact of cardiovascular risk factors and vascular closure devices on the femoral artery after repeat cardiac catheterizationKlaus A Tiroch
Department of Cardiovascular Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
Am Heart J 159:125-30. 2010..We evaluated the exact quantitative long-term impact of repeated catheterizations, vascular closure devices, and cardiovascular risk factors on the femoral artery after cardiac catheterization... - Automated surveillance to detect postprocedure safety signals of approved cardiovascular devicesFrederic S Resnic
BrighamandWomen s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
JAMA 304:2019-27. 2010..Automated surveillance of clinical registries may provide early warnings in the postmarket evaluation of medical device safety... - Clinical inertia of discharge planning among patients with poorly controlled diabetes mellitusMichelle L Griffith
Veterans Affairs Tennessee Valley Healthcare System, A 413 VA GRECC, 1310 24th Avenue South, Nashville, Tennessee 37212, USA
J Clin Endocrinol Metab 97:2019-26. 2012..We examined the effect of hospital admissions on the medical treatment of poorly controlled diabetes mellitus among Veterans Affairs (VA) patients... - Validation of long-term benefits of bivalirudin versus unfractionated heparin in routine clinical practice after percutaneous coronary interventionVenkatesan D Vidi
Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 106:1234-40. 2010.... - Detection of infectious symptoms from VA emergency department and primary care clinical documentationMichael E Matheny
Geriatrics Research, Education, and Clinical Care, Tennessee Valley Healthcare System, Veteran s Administration, Nashville, TN 37212, USA
Int J Med Inform 81:143-56. 2012.... - Analyses of longitudinal, hospital clinical laboratory data with application to blood glucose concentrationsJonathan S Schildcrout
Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN, USA
Stat Med 30:3208-20. 2011..To illustrate these points, we present a detailed analysis of the relationship between blood glucose levels and insulin doses on the basis of data from an intensive care unit... - Effects of SVM parameter optimization on discrimination and calibration for post-procedural PCI mortalityMichael E Matheny
Decision Systems Group, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
J Biomed Inform 40:688-97. 2007..The results were compared to those produced by logistic regression models optimized using the same indices. The choice of optimization parameters had a significant impact on performance in both SVM kernel types... - Commonly used surrogates for baseline renal function affect the classification and prognosis of acute kidney injuryEdward D Siew
Division of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
Kidney Int 77:536-42. 2010..Our study found that commonly used surrogates for baseline serum creatinine result in bi-directional misclassification of the incidence and prognosis of acute kidney injury in a hospital setting... - Detecting temporal expressions in medical narrativesRuth M Reeves
Geriatric Research Education and Clinical Center, Tennessee Valley Healthcare System, Department of Veterans Affairs, Nashville, TN, USA
Int J Med Inform 82:118-27. 2013..TTK was developed on newspaper articles. We extended TTK to support medical notes using veterans' affairs (VA) clinical notes and compared it to TTK... - Outpatient nephrology referral rates after acute kidney injuryEdward D Siew
Division of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA
J Am Soc Nephrol 23:305-12. 2012..Determining how to best identify survivors of AKI who are at highest risk for complications and progression of CKD could facilitate early nephrology-based interventions... - An evaluation of a distributed medical device safety surveillance system: the DELTA network studyVenkatesan D Vidi
Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Contemp Clin Trials 32:309-17. 2011.... - Vascular closure device failure in contemporary practiceVenkatesan D Vidi
Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
JACC Cardiovasc Interv 5:837-44. 2012..The goal of this study was to assess the frequency and predictors of vascular closure device (VCD) deployment failure, and its association with vascular complications of 3 commonly used VCDs... - Risk predictors of retroperitoneal hemorrhage following percutaneous coronary interventionKlaus A Tiroch
Brigham and Women s Hospital, Boston, MA, USA
Am J Cardiol 102:1473-6. 2008..VCD use was not independently associated with the development of RPH (p = 0.74). In conclusion, this large prospective cohort study identified CRI, but not VCD use, as an independent predictor for RPH and peripheral vascular disease... - Use of multiple imputation method to improve estimation of missing baseline serum creatinine in acute kidney injury researchEdward D Siew
Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, 116121st Avenue South, Nashville, TN 37232 2372, USA
Clin J Am Soc Nephrol 8:10-8. 2013..This study examined whether multiple imputation improved accuracy of estimating missing BCr beyond current recommendations to apply assumed estimated GFR (eGFR) of 75 ml/min per 1.73 m(2) (eGFR 75)... - Quantifying the learning curve in the use of a novel vascular closure device: an analysis of the NCDR (National Cardiovascular Data Registry) CathPCI registryFrederic S Resnic
Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
JACC Cardiovasc Interv 5:82-9. 2012..This study sought to quantify the learning curve for the safety and effectiveness of a newly introduced vascular closure device through evaluation of the NCDR (National Cardiovascular Data Registry) CathPCI clinical outcomes registry... - Prevalence and Clinical Significance of Discrepancies within Three Computerized Pre-Admission Medication ListsJosh F Peterson
Department of Biomedical Informatics, Vanderbilt University, Nashville, TN
AMIA Annu Symp Proc 2010:642-6. 2010..Potentially harmful medication discrepancies were found within all lists. The authors concluded no single list was sufficiently accurate to avoid serious medication errors... - Monitoring device safety in interventional cardiologyMichael E Matheny
Department of Radiology, Harvard Medical School, Boston, MA, USA
J Am Med Inform Assoc 13:180-7. 2006..S. Food and Drug Administration, but there are few systems to automate surveillance. Our objective was to develop a system to perform real-time monitoring of safety data using a variety of process control techniques... - Medication-error alerts for warfarin orders detected by a bar-code-assisted medication administration systemFern Fitzhenry
Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37212, USA
Am J Health Syst Pharm 68:434-41. 2011..Medication-error alerts for warfarin orders detected by a bar-code-assisted medication administration (BCMA) system were evaluated... - Prognosis in critical careLucila Ohno-Machado
Decision Systems Group, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Annu Rev Biomed Eng 8:567-99. 2006..We emphasize the importance of model calibration in this domain. In addition, we present a brief review of the statistical methodology, multiple logistic regression, which underlies most of the models currently used in critical care... - Who Said It? Establishing Professional Attribution among Authors of Veterans' Electronic Health RecordsRuth M Reeves
Health Services Research and Development, Tennessee Valley Healthcare System, Department of Veterans Affairs, 1310 24 Avenue South, Nashville, TN 37212, USA Department of Biomedical Informatics, Vanderbilt University Medical Center, 2209 Garland Avenue, Nashville, TN 37232, USA
AMIA Annu Symp Proc 2012:753-62. 2012..We evaluated and compared free form electronic signatures against LOINC note titles in categorizing the profession of EHR authors... - Detection of blood culture bacterial contamination using natural language processingMichael E Matheny
GRECC and Center for Health Services Research, Veterans Affairs Tennessee Valley Health System, Nashville, TN Division of General Internal Medicine and Public Health, Vanderbilt University MedicalCenter, Nashville, TN Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA
AMIA Annu Symp Proc 2009:411-5. 2009..0% for mapping the antibiotics and bacteria with appropriate sensitivity findings in the test data. The bacterial contamination detection algorithm had a sensitivity of 83.3% and a positive predictive value of 81.8%... - A propensity analysis of the risk of vascular complications after cardiac catheterization procedures with the use of vascular closure devicesNipun Arora
Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Am Heart J 153:606-11. 2007..The purpose of this study was to assess femoral arterial access-related vascular outcomes after invasive cardiology procedures with the routine use of VCDs... - Adverse drug event rates in six community hospitals and the potential impact of computerized physician order entry for preventionBalthasar L Hug
Division of General Internal Medicine, Brigham and Women s Hospital, Brigham Circle, 1620 Tremont St, 3rd Floor, Boston, MA, 02120 1613, USA
J Gen Intern Med 25:31-8. 2010..Medications represent a major cause of harm and are costly for hospitalized patients, but more is known about these issues in large academic hospitals than in smaller hospitals...