Research Topics
Species | Beth MalowSummaryAffiliation: Vanderbilt University Country: USA Publications
Research Grants
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Detail Information
Publications
Effects of a standardized pamphlet on insomnia in children with autism spectrum disordersKaren W Adkins
Vanderbilt University Medical Center, Nashville, Tennessee 37232
Pediatrics 130:S139-44. 2012..CONCLUSIONS A sleep education pamphlet did not appear to improve sleep latency in children with ASDs...- A practice pathway for the identification, evaluation, and management of insomnia in children and adolescents with autism spectrum disordersBeth A Malow
Burry Chair in Cognitive Childhood Development, Director, Vanderbilt Sleep Disorders Division, 1161 21st Avenue South, Room A 0116, Nashville, TN 37232
Pediatrics 130:S106-24. 2012.... 
Melatonin for sleep in children with autism: a controlled trial examining dose, tolerability, and outcomesBeth Malow
Sleep Disorders Division, Department of Neurology and Kennedy Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
J Autism Dev Disord 42:1729-37; author reply 1738. 2012..Our findings contribute to the growing literature on supplemental melatonin for insomnia in ASD and inform planning for a large randomized trial in this population...
The interaction between sleep and epilepsyBeth A Malow
Department of Neurology, Vanderbilt University, Medical Center North, Nashville, Tennessee 37232 2551, USA
Epilepsia 48:36-8. 2007..In this article, aspects related to the interrelationship of sleep and epilepsy will be discussed and the model of how sleep can interact with a neurological disorder will be illustrated...- Characterizing sleep in children with autism spectrum disorders: a multidimensional approachBeth A Malow
Sleep Disorders Division, Department of Neurology and Kennedy Center Vanderbilt University School of Medicine, Nashville, TN 37232 3375, USA
Sleep 29:1563-71. 2006..To relate parentally reported sleep concerns in autism spectrum disorders (ASD) to polysomnographic (PSG) findings and measures of daytime behavior and autism symptomatology... - Impact of treating sleep apnea in a child with autism spectrum disorderBeth A Malow
Department of Neurology and Kennedy Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Pediatr Neurol 34:325-8. 2006..Identification and treatment of sleep disorders, including obstructive sleep apnea, may improve daytime behavior in children with autism spectrum disorders... - Sleep and epilepsyBeth A Malow
Department of Neurology, Vanderbilt University School of Medicine, Nashville, TN 37212, USA
Neurol Clin 23:1127-47. 2005.... - Treating obstructive sleep apnea in adults with epilepsy: a randomized pilot trialB A Malow
Vanderbilt University, Department of Neurology, Medical Center North, Room A 0118, 1161 21st Avenue South, Nashville, TN 37232 2551, USA
Neurology 71:572-7. 2008..Prior to conducting a definitive randomized controlled trial, we addressed critical design issues in a pilot study... - Sleep disorders, epilepsy, and autismBeth A Malow
Vanderbilt Sleep Disorders Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37212, USA
Ment Retard Dev Disabil Res Rev 10:122-5. 2004..The article concludes with some practical suggestions for the evaluation and treatment of sleep disorders in this population of children with autism... - A sleep habits questionnaire for children with autism spectrum disordersBeth A Malow
Sleep Disorders Division, Department of Neurology and Kennedy Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
J Child Neurol 24:19-24. 2009..Age and socioeconomic status were not correlated with total score in either group. This preliminary work suggests that the Family Inventory of Sleep Habits is a valid and reliable measure of sleep hygiene in autism spectrum disorders... - Identification and treatment of obstructive sleep apnea in adults and children with epilepsy: a prospective pilot studyBeth A Malow
Michael S Aldrich Sleep Disorders Center, Department of Neurology, University of Michigan Medical Center, Ann Arbor, MI, USA
Sleep Med 4:509-15. 2003.... - Relationship of epileptic seizures to sleep stage and sleep depthDaniela Minecan
Department of Neurology, University of Michigan Medical School, USA
Sleep 25:899-904. 2002..To determine whether sleep influences seizures in a similar way to IEDs, we examined seizure rates in various stages of sleep in epilepsy patients undergoing overnight video-EEG-polysomnography (VPSG)... - Sleep disorders: a sometimes forgotten cause of nonepileptic spellsMihaela Mihaescu
Michael S. Aldrich Sleep Disorders Center, Department of Neurology, University of Michigan Medical Center, 2100 Pierce Avenue, 320 MCS, 37212-3375, Nashville, TN, USA
Epilepsy Behav 4:784-7. 2003..Sleep studies, including polysomnography and multiple sleep latency testing (MSLT), confirmed a sleep disorder, i.e., narcolepsy, which responded to specific therapy with resolution of the spells... - Obstructive sleep apnea is associated with seizure occurrence in older adults with epilepsyAnnette M Chihorek
Department of Neurology, Sleep Disorders Division, Vanderbilt University School of Medicine, Nashville, TN 37232 2551, USA
Neurology 69:1823-7. 2007..Our objective was to investigate whether OSA is associated with seizure exacerbation in older adults with epilepsy... - Analysis of the first night effect and sleep parameters in medically refractory epilepsy patientsMary L Marzec
Michael S Aldrich Sleep Disorders Center, Department of Neurology, University of Michigan Medical Center, 1500 E Medical Center Dr, Rm 8D 8702 Ann Arbor, MI 48109 0117, USA
Sleep Med 6:277-80. 2005..To assess the first night effect (FNE) and compare sleep stage proportions to normative values in a sample of medically refractory epilepsy patients... - Defining the sleep phenotype in children with autismSuzanne E Goldman
Sleep Disorders Division, Department of Neurology and Kennedy Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Dev Neuropsychol 34:560-73. 2009..Fragmentation was correlated with more restricted/repetitive behaviors. This work provides the foundation for focused studies of pathophysiology and targeted interventions to improve sleep in this population... - Paroxysmal events in sleepBeth A Malow
Michael S Aldrich Sleep Disorders Laboratory, University of Michigan, Ann Arbor, 48109 0117, USA
J Clin Neurophysiol 19:522-34. 2002..Essential historic elements that distinguish these events and the role of video-EEG-polysomnography in their differential diagnosis are emphasized... - A novel approach to treating morning sleep inertia in narcolepsyKanika Bagai
Vanderbilt Sleep Disorders Center, Nashville, TN, USA
J Clin Sleep Med 6:77-8. 2010..We present our experience with this unconventional treatment, which may benefit others with inability to awaken from sleep that is refractory to standard treatments... - Analysis of sleep parameters in patients with obstructive sleep apnea studied in a hospital vs. a hotel-based sleep centerKimberly N Hutchison
Department of Neurology, Vanderbilt University Medical Center, 1161 21st Avenue South, Room A 0106 MCN, Nashville, TN 37232 2551, USA
J Clin Sleep Med 4:119-22. 2008..In this study, we compared the sleep parameters of patients studied in our hotel-based and hospital-based sleep laboratories... - Evaluation of sleep disturbances in older adultsSumi Misra
Assistant Professor of Medicine and Geriatrics, Division of General Internal Medicine, Vanderbilt University Medical Center, Nashville Veteran s Affairs Hospital, 1310 24th Avenue South, Nashville, TN 37212, USA
Clin Geriatr Med 24:15-26, v. 2008..The clinical assessment of aging patients who have sleep complaints involves an in-depth multidisciplinary approach... - Sleep staging and respiratory events in refractory epilepsy patients: Is there a first night effect?Linda M Selwa
Department of Neurology, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0117, USA
Epilepsia 49:2063-8. 2008..We performed this analysis of possible first night effects (FNEs) on sleep and respiratory parameters in order to evaluate the need for two serial night polysomnograms (PSGs) to diagnose obstructive sleep apnea (OSA) in epilepsy patients... - Developmental and behavioral questionnaire for autism spectrum disordersSusan McGrew
Department of Pediatrics and Kennedy Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA
Pediatr Neurol 37:108-16. 2007..The Parental Concerns Questionnaire is a reliable screening instrument to assess parentally reported developmental and behavioral symptoms in children with autism spectrum disorders... - Vagal and sympathetic heart rate and blood pressure control in adult onset PHOX2B mutation-confirmed congenital central hypoventilation syndromeAndre Diedrich
Dept of Medicine, Division of Clinical Pharmacology, Autonomic Dysfunction Center, Vanderbilt University School of Medicine, Nashville, TN, USA
Clin Auton Res 17:177-85. 2007.... - PHOX2B mutation-confirmed congenital central hypoventilation syndrome: presentation in adulthoodNick A Antic
Adelaide Institute for Sleep Health, Repatriation General Hospital, Daw Park, South Australia, Australia, and Sleep Disorders Division, Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA
Am J Respir Crit Care Med 174:923-7. 2006..Report of these cases should lead to a more rapid identification of CCHS presenting in adulthood... - Subclinical rhythmic electrographic discharge of adults (SREDA) in REM sleepW Elon Fleming
Department of Neurology, University of Michigan, Michael S. Aldrich Sleep Disorders Center, UH Room 8D-8720, 1500 E. Medical Center Drive, Ann Arbor, MI 48109-0117, USA
Sleep Med 5:77-81. 2004..This uncommon paroxysmal electrographic pattern should not be mistaken for seizure activity and is now recognized to occur in all stages of sleep, including REM... - Sleep disturbances and diminished quality of life in postural tachycardia syndromeKanika Bagai
Paden Dysautonomia Center and Department of Neurology, Vanderbilt University, Nashville, TN, USA
J Clin Sleep Med 7:204-10. 2011..This study's objective was to assess the sleep quality and health-related quality of life in patients with POTS as compared with healthy control subjects... - Approaches to staging sleep in polysomnographic studies with epileptic activityMary L Marzec
Michael S. Aldrich Sleep Disorders Laboratory and the Epilepsy Program, Clinical Neurophysiology Section, Department of Neurology, University of Michigan Medical School, UH Room 8D-8702, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0117, USA
Sleep Med 4:409-17. 2003..These approaches to scoring PSGs of patients with epilepsy will require empirical testing... - Obstructive sleep apnea in epilepsy patients: the Sleep Apnea scale of the Sleep Disorders Questionnaire (SA-SDQ) is a useful screening instrument for obstructive sleep apnea in a disease-specific populationKevin J Weatherwax
Michael S Aldrich Sleep Disorders Center, Department of Neurology, University of Michigan Medical Center, University Hospital, 8D 8702, Box 0117, 1500 E Medical Center Drive, Ann Arbor, MI 48109 0117, USA
Sleep Med 4:517-21. 2003..To determine useful cutoffs on the Sleep Apnea scale of the Sleep Disorders Questionnaire (SA-SDQ) in an epilepsy population... - Obstructive sleep apnea is common in idiopathic pulmonary fibrosisLisa H Lancaster
Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232 5735, USA
Chest 136:772-8. 2009..Our goal was to analyze OSA in an outpatient population of stable patients with idiopathic pulmonary fibrosis (IPF)... - Parent-based sleep education workshops in autismHannah E Reed
Sleep Disorders Division, Department of Neurology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
J Child Neurol 24:936-45. 2009..Brief parent-based behavioral sleep workshops in children with autism spectrum disorders appear effective in improving subjective and objective measures of sleep, sleep habits, and daytime behavior... - Long-term outcome of nonsurgical candidates with medically refractory localization-related epilepsyLinda M Selwa
Department of Neurology, University of Michigan Medical School, 1500 East Medical Center Drive, 1914 0316 Taubman, Ann Arbor, MI 48109 0316, USA
Epilepsia 44:1568-72. 2003..In this study, we evaluated the outcome of medical treatment in patients with medically refractory partial epilepsy who were evaluated for possible epilepsy surgery but deemed to be inadequate surgical candidates... - Melatonin for insomnia in children with autism spectrum disordersIvy M Andersen
Sleep Disorders Division, Department of Neurology, Vanderbilt University School of Medicine, Nashville, TN 37232 2551, USA
J Child Neurol 23:482-5. 2008..The majority of children were taking psychotropic medications. Melatonin appears to be a safe and well-tolerated treatment for insomnia in children with autism spectrum disorders. Controlled trials to determine efficacy appear warranted... - Effects of vagus nerve stimulation on sleep-related breathing in epilepsy patientsMary Marzec
Michael S. Aldrich Sleep Disorders Laboratory and the Epilepsy Program, Clinical Neurophysiology Section, Department of Neurology, University of Michigan Medical School, Ann Arbor, Michigan, U.S.A
Epilepsia 44:930-5. 2003..The AHI after VNS treatment remained <5 in the majority of patients and was only mildly elevated (<12) in five patients. In one patient, CPAP resolved VNS-related respiratory events... - Interictal epileptiform discharges do not change before seizures during sleepAlamelu Natarajan
Department of Neurology, University of Michigan Medical School, Ann Arbor, Michigan, USA
Epilepsia 43:46-51. 2002..These results corroborate prior studies, while providing a more advanced analysis by adjusting for sleep depth and applying multivariate logistic regression analyses... - Blockade of endogenous growth hormone-releasing hormone receptors dissociates nocturnal growth hormone secretion and slow-wave sleepStacy K Jessup
Department of Internal Medicine, Division of Endocrinology and Metabolism, University of Michigan Medical Center, Ann Arbor, Michigan, USA
Eur J Endocrinol 151:561-6. 2004..Based on these data, a role for GHRH as an inducer of SWS was proposed. To test this hypothesis, we have performed the corollary experiment whereby the action of endogenous GHRH has been antagonized... - Partial epilepsy presenting as apneic seizures without posturingEdgard O Andrade
Department of Neurology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Pediatr Neurol 35:359-62. 2006..Polysomnography with extended electroencephalography and video is the gold standard tool to evaluate patients with apnea due to suspected seizures... - Sleep in children with autism spectrum disordersKyle P Johnson
Department of Psychiatry, Oregon Health and Science University, DC 7P, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
Curr Neurol Neurosci Rep 8:155-61. 2008..This article presents a discussion of the sleep problems experienced by children with one particular group of developmental disorders--the autism spectrum disorders...
Research Grants
- FACILITATION OF EPILEPTIC ACTIVITY BY SLEEP AND AROUSALBeth Malow; Fiscal Year: 2003..abstract_text> ..
- Effects of Treating Obstructive Sleep Apnea in EpilepsyBeth Malow; Fiscal Year: 2002..abstract_text> ..
- Effects of Treating Obstructive Sleep Apnea in EpilepsyBeth Malow; Fiscal Year: 2004..Develop quality control measures to ensure accurate and consistent data collection among sites in the RCT, including aspects related to remote data entry and standardization of performance and interpretation of PSG studies across sites...
- Melatonin for Sleep in Children with Autism: Safety, Tolerability, and DosingBeth Malow; Fiscal Year: 2009..We will determine the response of melatonin dose on sleep latency using polysomnography and actigraphy, a validated and non-intrusive measure of sleep onset and duration. Adverse events will also be captured. ..
- Melatonin for Sleep in Children with Autism: Safety, Tolerability, and DosingBeth Malow; Fiscal Year: 2009..We will determine the response of melatonin dose on sleep latency using polysomnography and actigraphy, a validated and non-intrusive measure of sleep onset and duration. Adverse events will also be captured. ..