Research Topics
Species | Tatsuki KoyamaSummaryAffiliation: Vanderbilt University Country: USA Publications
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Detail Information
Publications
A framework for two-stage adaptive procedures to simultaneously test non-inferiority and superiorityTatsuki Koyama
Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN 37232 6848, USA
Stat Med 24:2439-56. 2005..Based on the results at the end of stage I, the primary objective for stage II is chosen, and sample sizes and critical values for stage II are determined...- Decision-theoretic views on simultaneous testing of superiority and noninferiorityTatsuki Koyama
Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 6848, USA
J Biopharm Stat 15:943-55. 2005..We find that the simultaneous testing procedure generally provides smaller loss than Ng's method, except when the prior distribution allocates a large probability to equivalence of the two treatments... - Flexible design of two-stage adaptive procedures for phase III clinical trialsTatsuki Koyama
Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 6848, USA
Contemp Clin Trials 28:500-13. 2007..Furthermore, we show how to compute the P value, confidence interval and a reasonable point estimate for any design that can be placed under the proposed framework... - Proper inference from Simon's two-stage designsTatsuki Koyama
Department of Biostatistics, Vanderbilt University School of Medicine, 571 Preston Building, Nashville, TN 37232 6848, USA
Stat Med 27:3145-54. 2008..The conventional inference, however, may contradict the result of the corresponding hypothesis testing... 
Accuracy and reproducibility of a multiplex immunoassay platform: a validation studyJulie A Bastarache
Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, United States
J Immunol Methods 367:33-9. 2011..We sought to validate a specific multiplex cytokine immunoassay (Human 9-plex cytokine array on the Searchlight® platform by Thermoscientific) prior to use in a large clinical study...- Acute lung injury in patients with traumatic injuries: utility of a panel of biomarkers for diagnosis and pathogenesisRichard D Fremont
Division of Allergy, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 2650, USA
J Trauma 68:1121-7. 2010..The aims of this study were to develop a panel of plasma biomarkers to facilitate diagnosis of trauma-induced ALI and to enhance our understanding of the pathogenesis of human ALI... - Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injuryLorraine B Ware
DivisionAllergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232 2650, USA
Chest 137:288-96. 2010..We hypothesized that a combination of biologic and clinical markers would be superior to either biomarkers or clinical factors alone in predicting ALI/ARDS mortality and would provide insight into the pathogenesis of clinical ALI/ARDS... - Endoscopic ultrasound to guide the combined medical and surgical management of pediatric perianal Crohn's diseaseMichael J Rosen
Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Vanderbilt University School of Medicine, Nashville, TN 37232 0696, USA
Inflamm Bowel Dis 16:461-8. 2010.... - Ontogeny of FOXP3(+) regulatory T cells in the postnatal human small intestinal and large intestinal lamina propriaJörn Hendrik Weitkamp
Department of Pediatrics, Division of Neonatology, Monroe Carell Jr Children s Hospital at Vanderbilt, 2215 B Garland Avenue, 1125 MRB IV Light Hall, Nashville, TN 37232 0656, USA
Pediatr Dev Pathol 12:443-9. 2009..The frequency of FOXP3(+) cells and the ratios of FOXP3(+) to CD4(+) or CD8(+) cells do not change with increasing intrauterine development or postnatal age... - Use of fluoroscopy to study in vivo motility in mouse pupsKent Williams
Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
J Pediatr Gastroenterol Nutr 52:679-85. 2011..This study sought to determine whether digital fluoroscopy could be used to evaluate gastrointestinal motility in mouse pups as well as adult mice... 
Racial and ethnic differences in pediatric obesity-prevention counseling: national prevalence of clinician practicesChristopher M Branner
Department of Pediatric Gastroenterology, Vanderbilt University, Nashville, TN, USA
Obesity (Silver Spring) 16:690-4. 2008..To assess the frequency of clinician-reported delivery of obesity-prevention counseling (OPC) at well-child visits; evaluating for racial/ethnic discrepancies...- Calcaneal ultrasound bone densitometry is not a useful tool to screen patients with inflammatory bowel disease at high risk for metabolic bone diseaseDavid A Schwartz
Inflammatory Bowel Disease Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
Inflamm Bowel Dis 11:749-54. 2005..This would reduce the number of patients undergoing DXA testing unnecessarily. We tried to determine if calcaneal ultrasound bone densitometry is a useful tool in screening high-risk patients with IBD for metabolic bone disease... - Body mass index and blood pressure changes over the course of treatment of pediatric acute lymphoblastic leukemiaAdam J Esbenshade
Department of Pediatrics, Vanderbilt University School of Medicine and Monroe Carell Jr Children s Hospital at Vanderbilt, Nashville, Tennessee 37232, USA
Pediatr Blood Cancer 56:372-8. 2011..Obesity and hypertension are reported among survivors of pediatric acute lymphoblastic leukemia (ALL). However, little is known about the trajectory of body mass index (BMI) and blood pressure over the course of ALL therapy... - Impact of conditioning regimen in allogeneic hematopoetic stem cell transplantation for children with acute myelogenous leukemia beyond first complete remission: a pediatric blood and marrow transplant consortium (PBMTC) studyIndia Y Sisler
Vanderbilt University Medical Center, Nashville, Tennessee, USA
Biol Blood Marrow Transplant 15:1620-7. 2009..Our study provides no evidence of an advantage to using TBI in children with AML beyond CR1. A prospective, randomized study is needed to confirm these results... - Raf protects against colitis by promoting mouse colon epithelial cell survival through NF-kappaBKaren L Edelblum
Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA
Gastroenterology 135:539-51. 2008..This study addresses the role of Raf in epithelial cell survival in response to dextran sulfate sodium (DSS)-induced injury and inflammation... - Open-label pilot study of combination therapy with rosiglitazone and bexarotene in the treatment of cutaneous T-cell lymphomaJacob A Sepmeyer
Vanderbilt University School of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 5227, USA
J Am Acad Dermatol 56:584-7. 2007..After 16 weeks of combination therapy, skin score decreased in two patients. Pruritus was alleviated in 3 of 4 patients, whereas quality of life was unchanged. Adverse events included hyperlipidemia, anemia, neutropenia, and lymphopenia... - Chemokine markers predict biochemical recurrence of prostate cancer following prostatectomyDavid L Blum
Department of Urologic Surgery, Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37232, USA
Clin Cancer Res 14:7790-7. 2008..Inflammation has emerged as a mediator of prostate cancer metastatic progression. We hypothesized that chemokines can be biomarkers for distinguishing patients with high risk for biochemical recurrence of prostate cancer...