Zeljka Korade

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. ncbi Wnt signaling as a potential therapeutic target for frontotemporal dementia
    Zeljka Korade
    Department of Psychiatry and Vanderbilt Kennedy Center for Research on Human Development, Vanderbilt University, Nashville, TN 37232, USA
    Neuron 71:955-7. 2011
  2. ncbi NRIF is a regulator of neuronal cholesterol biosynthesis genes
    Zeljka Korade
    Department of Biochemistry, Vanderbilt University School of Medicine, 8124A MRB III, Nashville, TN 37232, USA
    J Mol Neurosci 38:152-8. 2009
  3. ncbi Molecular consequences of altered neuronal cholesterol biosynthesis
    Zeljka Korade
    Department of Biochemistry, Vanderbilt University, Nashville, Tennessee 37232, USA
    J Neurosci Res 87:866-75. 2009
  4. ncbi DHCEO accumulation is a critical mediator of pathophysiology in a Smith-Lemli-Opitz syndrome model
    Libin Xu
    Department of Chemistry and Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37235, USA
    Neurobiol Dis 45:923-9. 2012
  5. ncbi Biological activities of 7-dehydrocholesterol-derived oxysterols: implications for Smith-Lemli-Opitz syndrome
    Zeljka Korade
    Department of Chemistry and Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37235, USA
    J Lipid Res 51:3259-69. 2010
  6. ncbi p75 neurotrophin receptor-mediated apoptosis in sympathetic neurons involves a biphasic activation of JNK and up-regulation of tumor necrosis factor-alpha-converting enzyme/ADAM17
    Rajappa S Kenchappa
    Department of Biochemistry and Center for Molecular Neuroscience, Vanderbilt University Medical School, Nashville, Tennessee 37232, USA
    J Biol Chem 285:20358-68. 2010
  7. ncbi An oxysterol biomarker for 7-dehydrocholesterol oxidation in cell/mouse models for Smith-Lemli-Opitz syndrome
    Libin Xu
    Department of Chemistry and Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37235, USA
    J Lipid Res 52:1222-33. 2011
  8. ncbi Oxysterols from free radical chain oxidation of 7-dehydrocholesterol: product and mechanistic studies
    Libin Xu
    Department of Chemistry and Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37235, USA
    J Am Chem Soc 132:2222-32. 2010
  9. ncbi Lipid rafts, cholesterol, and the brain
    Zeljka Korade
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Neuropharmacology 55:1265-73. 2008
  10. ncbi Protein kinase A-induced phosphorylation of the p65 subunit of nuclear factor-kappaB promotes Schwann cell differentiation into a myelinating phenotype
    Choya Yoon
    Department of Biochemistry, Vanderbilt University Medical School, Nashville, Tennessee 37232, USA
    J Neurosci 28:3738-46. 2008

Collaborators

Detail Information

Publications10

  1. ncbi Wnt signaling as a potential therapeutic target for frontotemporal dementia
    Zeljka Korade
    Department of Psychiatry and Vanderbilt Kennedy Center for Research on Human Development, Vanderbilt University, Nashville, TN 37232, USA
    Neuron 71:955-7. 2011
    ..New data by Geschwind and colleagues in this issue of Neuron uncovered that the Wnt/FZD2 signaling pathway is an early and critical contributor to disease pathology...
  2. ncbi NRIF is a regulator of neuronal cholesterol biosynthesis genes
    Zeljka Korade
    Department of Biochemistry, Vanderbilt University School of Medicine, 8124A MRB III, Nashville, TN 37232, USA
    J Mol Neurosci 38:152-8. 2009
    ..Our combined in vitro and in vivo studies suggest that hippocampal neuronal cholesterol biosynthesis is regulated through the p75NTR interacting factor NRIF...
  3. ncbi Molecular consequences of altered neuronal cholesterol biosynthesis
    Zeljka Korade
    Department of Biochemistry, Vanderbilt University, Nashville, Tennessee 37232, USA
    J Neurosci Res 87:866-75. 2009
    ....
  4. ncbi DHCEO accumulation is a critical mediator of pathophysiology in a Smith-Lemli-Opitz syndrome model
    Libin Xu
    Department of Chemistry and Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37235, USA
    Neurobiol Dis 45:923-9. 2012
    ..The future studies will test if antioxidant supplementation will ameliorate some of the clinical symptoms associated with this devastating disease...
  5. ncbi Biological activities of 7-dehydrocholesterol-derived oxysterols: implications for Smith-Lemli-Opitz syndrome
    Zeljka Korade
    Department of Chemistry and Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37235, USA
    J Lipid Res 51:3259-69. 2010
    ....
  6. ncbi p75 neurotrophin receptor-mediated apoptosis in sympathetic neurons involves a biphasic activation of JNK and up-regulation of tumor necrosis factor-alpha-converting enzyme/ADAM17
    Rajappa S Kenchappa
    Department of Biochemistry and Center for Molecular Neuroscience, Vanderbilt University Medical School, Nashville, Tennessee 37232, USA
    J Biol Chem 285:20358-68. 2010
    ....
  7. ncbi An oxysterol biomarker for 7-dehydrocholesterol oxidation in cell/mouse models for Smith-Lemli-Opitz syndrome
    Libin Xu
    Department of Chemistry and Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37235, USA
    J Lipid Res 52:1222-33. 2011
    ..In a preliminary test, a pyrimidinol antioxidant was found to effectively suppress the formation of DHCEO in SLOS fibroblasts...
  8. ncbi Oxysterols from free radical chain oxidation of 7-dehydrocholesterol: product and mechanistic studies
    Libin Xu
    Department of Chemistry and Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37235, USA
    J Am Chem Soc 132:2222-32. 2010
    ....
  9. ncbi Lipid rafts, cholesterol, and the brain
    Zeljka Korade
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Neuropharmacology 55:1265-73. 2008
    ....
  10. ncbi Protein kinase A-induced phosphorylation of the p65 subunit of nuclear factor-kappaB promotes Schwann cell differentiation into a myelinating phenotype
    Choya Yoon
    Department of Biochemistry, Vanderbilt University Medical School, Nashville, Tennessee 37232, USA
    J Neurosci 28:3738-46. 2008
    ....