BJORN C contact KNOLLMANN

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. pmc Induced pluripotent stem cell-derived cardiomyocytes: boutique science or valuable arrhythmia model?
    Bjorn C Knollmann
    Department of Medicine, Division of Clinical Pharmacology, Vanderbilt University Medical School, Nashville, TN 37232 0575, USA
    Circ Res 112:969-76; discussion 976. 2013
  2. pmc Accelerated sinus rhythm prevents catecholaminergic polymorphic ventricular tachycardia in mice and in patients
    Michela Faggioni
    Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232 0575, USA
    Circ Res 112:689-97. 2013
  3. pmc Coordinated regulation of murine cardiomyocyte contractility by nanomolar (-)-epigallocatechin-3-gallate, the major green tea catechin
    Wei Feng
    Department of Molecular Biosciences, University of California, Davis, California, USA
    Mol Pharmacol 82:993-1000. 2012
  4. pmc Myofilament Ca sensitization increases cytosolic Ca binding affinity, alters intracellular Ca homeostasis, and causes pause-dependent Ca-triggered arrhythmia
    Tilmann Schober
    Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical School, Nashville, TN, USA
    Circ Res 111:170-9. 2012
  5. pmc Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia
    Bjorn C Knollmann
    Oates Institute for Experimental Therapeutics and Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232 0575, USA
    J Clin Invest 116:2510-20. 2006
  6. ncbi request reprint Action potential characterization in intact mouse heart: steady-state cycle length dependence and electrical restitution
    Bjorn C Knollmann
    Oates Institute for Experimental Therapeutics, Vanderbilt Univ School of Medicine, Division of Clinical Pharmacology, 1265 Medical Research Bldg IV, Nashville, TN 37232 0575, USA
    Am J Physiol Heart Circ Physiol 292:H614-21. 2007
  7. pmc New roles of calsequestrin and triadin in cardiac muscle
    Bjorn C Knollmann
    Depts of Medicine and Pharmacology, Vanderbilt Univ, Nashville, TN 37232, USA
    J Physiol 587:3081-7. 2009

Research Grants

  1. Troponin T mutations and Sudden Cardiac Death
    Bjorn Knollmann; Fiscal Year: 2003
  2. Calsequestrin in Ventricular Arrhythmia and Sudden Death
    Bjorn C Knollmann; Fiscal Year: 2010
  3. Arrhythmia Mechanisms in Sarcomeric Cardiomyopathies
    Bjorn Knollmann; Fiscal Year: 2009
  4. Calsequestrin in Ventricular Arrhythmia and Sudden Death
    Bjorn Knollmann; Fiscal Year: 2009
  5. Calsequestrin in Ventricular Arrhythmia and Sudden Death
    Bjorn Knollmann; Fiscal Year: 2007
  6. Troponin T mutations and Sudden Cardiac Death
    Bjorn Knollmann; Fiscal Year: 2005
  7. Troponin T mutations and Sudden Cardiac Death
    Bjorn Knollmann; Fiscal Year: 2006
  8. Troponin T mutations and Sudden Cardiac Death
    Bjorn Knollmann; Fiscal Year: 2005
  9. Troponin T mutations and Sudden Cardiac Death
    Bjorn Knollmann; Fiscal Year: 2004
  10. Arrhythmia Mechanisms in Sarcomeric Cardiomyopathies
    BJORN C contact KNOLLMANN; Fiscal Year: 2010

Collaborators

Detail Information

Publications7

  1. pmc Induced pluripotent stem cell-derived cardiomyocytes: boutique science or valuable arrhythmia model?
    Bjorn C Knollmann
    Department of Medicine, Division of Clinical Pharmacology, Vanderbilt University Medical School, Nashville, TN 37232 0575, USA
    Circ Res 112:969-76; discussion 976. 2013
    ....
  2. pmc Accelerated sinus rhythm prevents catecholaminergic polymorphic ventricular tachycardia in mice and in patients
    Michela Faggioni
    Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232 0575, USA
    Circ Res 112:689-97. 2013
    ..Sinoatrial node dysfunction associated with CPVT may increase the risk for ventricular arrhythmia (VA)...
  3. pmc Coordinated regulation of murine cardiomyocyte contractility by nanomolar (-)-epigallocatechin-3-gallate, the major green tea catechin
    Wei Feng
    Department of Molecular Biosciences, University of California, Davis, California, USA
    Mol Pharmacol 82:993-1000. 2012
    ....
  4. pmc Myofilament Ca sensitization increases cytosolic Ca binding affinity, alters intracellular Ca homeostasis, and causes pause-dependent Ca-triggered arrhythmia
    Tilmann Schober
    Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical School, Nashville, TN, USA
    Circ Res 111:170-9. 2012
    ..In mice, Ca sensitization causes ventricular arrhythmias, but the underlying mechanisms remain unclear...
  5. pmc Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia
    Bjorn C Knollmann
    Oates Institute for Experimental Therapeutics and Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232 0575, USA
    J Clin Invest 116:2510-20. 2006
    ....
  6. ncbi request reprint Action potential characterization in intact mouse heart: steady-state cycle length dependence and electrical restitution
    Bjorn C Knollmann
    Oates Institute for Experimental Therapeutics, Vanderbilt Univ School of Medicine, Division of Clinical Pharmacology, 1265 Medical Research Bldg IV, Nashville, TN 37232 0575, USA
    Am J Physiol Heart Circ Physiol 292:H614-21. 2007
    ..We conclude that mouse myocardium shows AP cycle length dependence and electrical restitution properties that are surprisingly similar to those of larger mammals and humans...
  7. pmc New roles of calsequestrin and triadin in cardiac muscle
    Bjorn C Knollmann
    Depts of Medicine and Pharmacology, Vanderbilt Univ, Nashville, TN 37232, USA
    J Physiol 587:3081-7. 2009
    ....

Research Grants12

  1. Troponin T mutations and Sudden Cardiac Death
    Bjorn Knollmann; Fiscal Year: 2003
    ..If validated by this research, the proposed mechanism of arrhythmogenesis may be applicable to other FHC mutations and diseases that increase myofilament Ca 2+ sensitivity. ..
  2. Calsequestrin in Ventricular Arrhythmia and Sudden Death
    Bjorn C Knollmann; Fiscal Year: 2010
    ....
  3. Arrhythmia Mechanisms in Sarcomeric Cardiomyopathies
    Bjorn Knollmann; Fiscal Year: 2009
    ..The proposed research focuses on discovering the underlying mechanism(s) responsible for the arrhythmias. Result from our studies may provide new therapeutic strategies for this presently incurable disease. ..
  4. Calsequestrin in Ventricular Arrhythmia and Sudden Death
    Bjorn Knollmann; Fiscal Year: 2009
    ....
  5. Calsequestrin in Ventricular Arrhythmia and Sudden Death
    Bjorn Knollmann; Fiscal Year: 2007
    ....
  6. Troponin T mutations and Sudden Cardiac Death
    Bjorn Knollmann; Fiscal Year: 2005
    ..If validated by this research, the proposed mechanism of arrhythmogenesis may be applicable to other FHC mutations and diseases that increase myofilament Ca 2+ sensitivity. ..
  7. Troponin T mutations and Sudden Cardiac Death
    Bjorn Knollmann; Fiscal Year: 2006
    ..If validated by this research, the proposed mechanism of arrhythmogenesis may be applicable to other FHC mutations and diseases that increase myofilament Ca 2+ sensitivity. ..
  8. Troponin T mutations and Sudden Cardiac Death
    Bjorn Knollmann; Fiscal Year: 2005
    ..If validated by this research, the proposed mechanism of arrhythmogenesis may be applicable to other FHC mutations and diseases that increase myofilament Ca 2+ sensitivity. ..
  9. Troponin T mutations and Sudden Cardiac Death
    Bjorn Knollmann; Fiscal Year: 2004
    ..If validated by this research, the proposed mechanism of arrhythmogenesis may be applicable to other FHC mutations and diseases that increase myofilament Ca 2+ sensitivity. ..
  10. Arrhythmia Mechanisms in Sarcomeric Cardiomyopathies
    BJORN C contact KNOLLMANN; Fiscal Year: 2010
    ..The proposed research focuses on discovering the underlying mechanism(s) responsible for the arrhythmias. Result from our studies may provide new therapeutic strategies for this presently incurable disease. ..