Madan Jagasia

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. doi request reprint Extracorporeal photopheresis versus anticytokine therapy as a second-line treatment for steroid-refractory acute GVHD: a multicenter comparative analysis
    Madan Jagasia
    Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    Biol Blood Marrow Transplant 19:1129-33. 2013
  2. doi request reprint Palifermin for the reduction of acute GVHD: a randomized, double-blind, placebo-controlled trial
    M H Jagasia
    Hematology and Stem Cell Transplant, Vanderbilt Ingram Cancer Center, Nashville, TN, USA
    Bone Marrow Transplant 47:1350-5. 2012
  3. ncbi request reprint Genetic variation in donor CTLA-4 regulatory region is a strong predictor of outcome after allogeneic hematopoietic cell transplantation for hematologic malignancies
    Madan Jagasia
    Hematology and Stem Cell Transplantation Section, Division of Hematology Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Biol Blood Marrow Transplant 18:1069-75. 2012
  4. ncbi request reprint Outcome, toxicity profile and cost analysis of autologous stem cell mobilization
    M H Jagasia
    Division of Hematology Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 5505, USA
    Bone Marrow Transplant 46:1084-8. 2011
  5. ncbi request reprint Histology impacts the outcome of peripheral T-cell lymphomas after high dose chemotherapy and stem cell transplant
    Madan Jagasia
    Division of Hematology Oncology, Department of Internal Medicine, Vanderbilt University Medical Center, 2665 TVC, Nashville, TN 37232 5505
    Leuk Lymphoma 45:2261-7. 2004
  6. ncbi request reprint Incidence and outcome of chronic graft-versus-host disease using National Institutes of Health consensus criteria
    Madan Jagasia
    Division of Hematology Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Biol Blood Marrow Transplant 13:1207-15. 2007
  7. ncbi request reprint Geographic distance is not associated with inferior outcome when using long-term transplant clinic strategy
    Brittany Knick Ragon
    Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee
    Biol Blood Marrow Transplant 20:53-7. 2014
  8. pmc Tissue-specific regulatory T cells: biomarker for acute graft-vs-host disease and survival
    Brian G Engelhardt
    Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 2905, USA
    Exp Hematol 40:974-982.e1. 2012
  9. pmc Immunomodulatory nonablative conditioning regimen for B-cell lymphoid malignancies
    Wichai Chinratanalab
    Hematology and Stem Cell Transplantation Section, Division of Hematology Oncology, Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Exp Hematol 40:431-5. 2012
  10. doi request reprint Time to explore preventive and novel therapies for bronchiolitis obliterans syndrome after allogeneic hematopoietic stem cell transplantation
    Salyka M Sengsayadeth
    Section of Hematology and Stem Cell Transplantation, Division of Hematology Oncology, Department of Medicine, Vanderbilt Ingram Cancer Center, Nashville, TN 37232, USA
    Biol Blood Marrow Transplant 18:1479-87. 2012

Collaborators

Detail Information

Publications22

  1. doi request reprint Extracorporeal photopheresis versus anticytokine therapy as a second-line treatment for steroid-refractory acute GVHD: a multicenter comparative analysis
    Madan Jagasia
    Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    Biol Blood Marrow Transplant 19:1129-33. 2013
    ..Grade >II aGVHD at onset of salvage therapy (HR, 9.4; P < .001) and lack of response to therapy (HR, 3.09; P = .011) were associated with inferior survival. These findings require validation in a prospective randomized study...
  2. doi request reprint Palifermin for the reduction of acute GVHD: a randomized, double-blind, placebo-controlled trial
    M H Jagasia
    Hematology and Stem Cell Transplant, Vanderbilt Ingram Cancer Center, Nashville, TN, USA
    Bone Marrow Transplant 47:1350-5. 2012
    ..c. events such as rash, pruritus, and erythema. This exploratory study of acute GVHD after myeloablation and allo-SCT did not provide evidence of a treatment effect with this dosing regimen of palifermin...
  3. ncbi request reprint Genetic variation in donor CTLA-4 regulatory region is a strong predictor of outcome after allogeneic hematopoietic cell transplantation for hematologic malignancies
    Madan Jagasia
    Hematology and Stem Cell Transplantation Section, Division of Hematology Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Biol Blood Marrow Transplant 18:1069-75. 2012
    ..10-2.71, P = .017) and OS (HR = 1.84, 95% CI 1.13-3.0, P = .015). CTLA-4 SNPs can be used to identify high-risk patient subsets that may benefit from preemptive immunomodulation to decrease relapse rates and improve survival...
  4. ncbi request reprint Outcome, toxicity profile and cost analysis of autologous stem cell mobilization
    M H Jagasia
    Division of Hematology Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 5505, USA
    Bone Marrow Transplant 46:1084-8. 2011
    ..04). Although mobilization success is eventually realized with CY+G, it has a low rate of ideal outcome, associated with significant adverse events and costs...
  5. ncbi request reprint Histology impacts the outcome of peripheral T-cell lymphomas after high dose chemotherapy and stem cell transplant
    Madan Jagasia
    Division of Hematology Oncology, Department of Internal Medicine, Vanderbilt University Medical Center, 2665 TVC, Nashville, TN 37232 5505
    Leuk Lymphoma 45:2261-7. 2004
    ..ALCL histology confers better survival compared to non-ALCL and DLBCL histologies. ALK-positive ALCL is associated with the best EFS after relapse with HDC and SCT. The timing of SCT for non-ALCL histology remains to be determined...
  6. ncbi request reprint Incidence and outcome of chronic graft-versus-host disease using National Institutes of Health consensus criteria
    Madan Jagasia
    Division of Hematology Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Biol Blood Marrow Transplant 13:1207-15. 2007
    ..36, P = .0144) were significant independent predictors of survival. The OS with different NIH subtypes of GVHD after day 100 from SCT varies, and is superior for patients with classic cGVHD...
  7. ncbi request reprint Geographic distance is not associated with inferior outcome when using long-term transplant clinic strategy
    Brittany Knick Ragon
    Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee
    Biol Blood Marrow Transplant 20:53-7. 2014
    ..Our study suggests that geographic distance from the transplant center is not associated with inferior outcome when follow-up care is delivered via a dedicated LTTC incorporating well-coordinated multidisciplinary care...
  8. pmc Tissue-specific regulatory T cells: biomarker for acute graft-vs-host disease and survival
    Brian G Engelhardt
    Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 2905, USA
    Exp Hematol 40:974-982.e1. 2012
    ....
  9. pmc Immunomodulatory nonablative conditioning regimen for B-cell lymphoid malignancies
    Wichai Chinratanalab
    Hematology and Stem Cell Transplantation Section, Division of Hematology Oncology, Department of Medicine, Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Exp Hematol 40:431-5. 2012
    ....
  10. doi request reprint Time to explore preventive and novel therapies for bronchiolitis obliterans syndrome after allogeneic hematopoietic stem cell transplantation
    Salyka M Sengsayadeth
    Section of Hematology and Stem Cell Transplantation, Division of Hematology Oncology, Department of Medicine, Vanderbilt Ingram Cancer Center, Nashville, TN 37232, USA
    Biol Blood Marrow Transplant 18:1479-87. 2012
    ..Therapeutic trials continue to be needed for this orphan disease...
  11. pmc Predicting posttransplantation diabetes mellitus by regulatory T-cell phenotype: implications for metabolic intervention to modulate alloreactivity
    Brian G Engelhardt
    Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    Blood 119:2417-21. 2012
    ..1; P = .020). PTDM is associated with altered immune regulation after HSCT and could represent a target to modulate alloreactivity...
  12. doi request reprint New allergies after cord blood transplantation
    Leigh Ann Vaughan
    Hematology and Stem Cell Transplantation Section, Division of Hematology Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Cytotherapy 15:1259-65. 2013
    ..Late effects of CBT are not well described in the literature. In the present study, we present our experience of new-onset allergies in long-term survivors after CBT...
  13. pmc Risk factors for acute GVHD and survival after hematopoietic cell transplantation
    Madan Jagasia
    Vanderbilt University Medical Center, Nashville, TN 37232 5505, USA
    Blood 119:296-307. 2012
    ..Conditioning intensity, TBI and graft source have a combined effect on risk of AGVHD that must be considered in deciding on a treatment strategy for individual patients...
  14. doi request reprint Pathology of graft-versus-host disease in the gastrointestinal tract
    Kay Washington
    Department of Pathology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Hum Pathol 40:909-17. 2009
    ..This review summarizes the histopathologic features of GVHD in the GI tract and outlines recent recommendations for reporting of GI biopsies with suspected GVHD...
  15. doi request reprint Early lymphocyte reconstitution is associated with improved transplant outcome after cord blood transplantation
    Sara K Tedeschi
    Hematology and Stem Cell Transplantation Section, Division of Hematology Oncology, Department of Medicine, Vanderbilt University Medical Center and Veterans Affairs Medical Center, Nashville, TN 37232 5505, USA
    Cytotherapy 13:78-82. 2011
    ..No consistent association has been reported between lymphocyte recovery and transplant outcome after cord blood transplantation (CBT)...
  16. pmc Time to consider HPV vaccination after allogeneic stem cell transplantation
    Sara K Tedeschi
    Long Term Follow up Transplant Clinic LTTC, Hematology and Stem Cell Transplantation Section, Division of Hematology Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232 5505, USA
    Biol Blood Marrow Transplant 16:1033-6. 2010
    ..It is time to evaluate the immunogenicity and efficacy in preventing HPV-related squamous cell carcinoma in this population...
  17. pmc Cytotoxic T-lymphocyte antigen-4 single nucleotide polymorphisms are not associated with outcomes after unrelated donor transplantation: a center for international blood and marrow transplant research analysis
    Salyka Sengsayadeth
    Section of Hematology and Stem Cell Transplantation, Vanderbilt Ingram Cancer Center, Nashville, Tennessee Electronic address
    Biol Blood Marrow Transplant 20:900-3. 2014
    ..An exploratory analysis of other CTLA-4 SNPs, as well as studying the interaction with antithymocyte globulin, also demonstrated no significant associations. Our results indicate that CTLA-4 SNPs are not associated with HSCT outcomes. ..
  18. doi request reprint Diabetes mellitus after hematopoietic stem cell transplantation
    Michelle L Griffith
    Division of Diabetes, Endocrinology and Metabolism, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 8148, USA
    Endocr Pract 16:699-706. 2010
    ..To review the current literature on posttransplant diabetes mellitus after hematopoietic stem cell transplantation, including its epidemiologic features, transplant-related risk factors, and treatment...
  19. pmc Innovative analyses support a role for DNA damage and an aberrant cell cycle in myelodysplastic syndrome pathogenesis
    David R Head
    Vanderbilt University Medical Center, Nashville, TN 37232 5310, USA
    Bone Marrow Res 2011:950934. 2011
    ..Our results suggest that peripheral cytopenias in MDS are due to delayed cell cycle passage of marrow progenitors and that this delayed passage and leukemic progression derive from excessive DNA damage...
  20. ncbi request reprint Gastric graft-versus-host disease revisited: does proton pump inhibitor therapy affect endoscopic gastric biopsy interpretation?
    Derek C Welch
    Department of Pathology, Division of Gastroenterology, Vanderbilt Medical Center, Nashville, TN 37232 2561, USA
    Am J Surg Pathol 30:444-9. 2006
    ..A similar increase in apoptosis was not seen in fundic biopsies; biopsy of the gastric fundus rather than antrum may be preferable for the diagnosis of upper gastrointestinal GvHD...
  21. ncbi request reprint Erdheim-chester disease mimicking multiple meningiomas syndrome
    Mahlon D Johnson
    Department of Pathology, Vanderbilt Medical School, Nashville, TN 37232, USA
    AJNR Am J Neuroradiol 25:134-7. 2004
    ..Biopsy of one orbital mass revealed a non-Langerhans histiocytosis. Subsequently, soft tissue masses, a pericardial effusion, and bone lesions consistent with ECD were identified...
  22. ncbi request reprint Individual physician practice variation in hematopoietic cell transplantation
    Stephanie J Lee
    Division of Clinical Research, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, D5 290, Seattle, WA 98109, USA
    J Clin Oncol 26:2162-70. 2008
    ..Previous studies have evaluated practice variation in hematopoietic cell transplantation (HCT) among transplant centers and countries. There are no studies investigating individual physician practice variation in HCT...